INTRODUCTION. Implant wear testing is traditionally undertaken using standardized inputs set out by ISO or ASTM. These inputs are based on a single individual performing a single activity with a specific implant. Standardization helps ensure that implants are tested to a known set of parameters from which comparisons may be drawn but it has limitations as patients perform varied activities, with different implant sizes and designs that produce different kinematics/kinetics. In this study, wear performance has been evaluated using gait implant specific loading/kinematics and comparing to a combination deep knee bend (DKB), step down (SD) and gait implant specific loading on cruciate retaining (CR) rotating platform (RP) total knee replacements (TKR). This combination activity profile better replicates patient activities of daily living (ADL). METHODS. Two sets of three ATTUNE. ®. size 5 right leg CR RP TKRs (DePuy Synthes, Warsaw, IN) were used in a study to evaluate ADL implant wear. Implant specific loading profiles were produced via a validated finite element lower limb model [1] that uses activity data such as gait (K1L_110108_1_86p), SD (K1L_240309_2_144p), and DKB (K9P_2239_0_9_I1) from the Orthoload database [2] to produce external boundary conditions. Each set of components were tested using a VIVO joint simulator (AMTI, Watertown, MA, Figure 1) for a total of 4.5 million cycles (Mcyc). All cycles were conducted at 0.8Hz in force-control with flexion driven in displacement control. Bovine calf serum lubricant was prepared to a total protein concentration of 18g/L and maintained at 37°±2°C. Wear of the tibial inserts was quantified via gravimetric methods per ISO14243–2:2009(E). Polyethylene tibial insert weights were taken prior to testing and every 0.5Mcyc there after which corresponded to serum exchange intervals. The multi-activity test intervals were split into10 loops of 1,250 DKB, 3,000 SD, and 45,750 gait cycles in series. Based on activity data presented by Wimmer et al. the number of cycles per activity and activities used is sufficient for a person that is considered active [3]. A loaded soak control was used to compensate for fluid absorption in wear rate calculations. Wear rates were calculated using linear regression. RESULTS SECTION. The wear rate for the gait-only activity test was calculated to be 0.20±0.04mg/Mcyc conversely the wear rate for the multi-activity test was 2.65±0.67mg/Mcyc (Figure 2). Wear scars can be found in Figure 3. Using a two-sided t-test of unequal variance, it was found that there was a significant difference between the two wear rates (p=0.004). DISCUSSION. Adding activities to the wear simulation test significantly increased the average wear rate of the test samples, confirming that changes in cross shear from different activities will tend to increase the wear of an implant. The results of this study prove that single activity wear testing may not be the most clinically severe wear testing that can be used for pre-clinical wear assessment. For any figures or tables, please contact the authors directly

Posterior stabilized (PS) total knee arthroplasty (TKA), wherein mechanical engagement of the femoral cam and tibial post prevents abnormal anterior sliding of the knee, is a proven surgical technique. However, many patients complain about abnormal clicking sensation, and several reports of severe wear and catastrophic failure of the tibial post have been published. In addition to posterior cam-post engagement during flexion, anterior engagement with femoral intercondylar notch can also occur during extension. The goal of this study was to use dynamic simulations to explore sensitivity of tibial post loading to implant design and alignment, across different activities. LifeModeler KneeSIM software was used to calculate tibial post contact forces for four contemporary PS implants (Triathlon PS, Stryker; Journey BCS and Legion PS, Smith & Nephew; LPS Flex, Zimmer Biomet). An average model of the knee, including cartilage and soft tissue insertion locations, created from MRI data of 40 knees was used to mount and align the component. The Triathlon femoral component was mounted with posterior and distal condylar tangency at: a) both medial and lateral condylar cartilage (anatomic alignment), b) at the medial condylar cartilage and perpendicular to mechanical axis (mechanical alignment with medial tangency), and c) at lateral condylar cartilage and perpendicular to mechanical axis (mechanical alignment with lateral tangency). The influence of implant design was assessed via simulations for the other implant systems with the femoral components aligned perpendicular to mechanical axis with lateral tangency. Five different activities were simulated. The anterior contact force was significantly smaller than the posterior contact force, but it varied noticeably with tibial insert slope and implant design. For Triathlon PS, during most activities anatomic alignment of the femoral component resulted in greater anterior contact force compared to mechanical alignment, but absolute magnitude of forces remained small (<100N). Mechanical alignment with medial tangency resulted in greater posterior contact force for deep knee bend and greater anterior force for chair sit activity. For all implants, peak posterior contact forces were greater for activities with greater peak knee flexion. The magnitude of posterior contact forces for the various implants was comparable to other reports in literature. Overall activity type, implant design and slope had greater impact on post loading than alignment method. Tibial insert slope was shown to be important for anterior post loading, but not for posterior post loading. Anatomic alignment could increase post loading with contemporary TKA systems. In the case of the specific design for which effect of alignment was evaluated, the changes in force magnitude with alignment were modest (<200N). Nonetheless, results of this study highlight the importance of evaluating the effect of different alignment approaches on tibial post loading

Background. Distal femoral replacements (DFR) are used in children for limb-salvage procedures after bone tumor surgery. These are typically modular devices involving a hinged knee axle that has peripheral metal-on-polyethylene (MoP) and central metal-on-metal (M-M) articulations. While modular connections and M-M surfaces in hip devices have been extensively studied, little is known about long-term wear or corrosion mechanisms of DFRs. Retrieved axles were examined to identify common features and patterns of surface damage, wear and corrosion. Methods. The cobalt chromium alloy axle components from 13 retrieved DFRs were cleaned and examined by eye and with a stereo microscope up to 1000× magnification. Each axle was marked into 6 zones for visual inspection: the proximal and distal views, and the middle (M-M) and 2 peripheral (MoP) zones. The approximate percentage of the following features were recorded per zone: polishing, abrasion or scratching, gouges or detectable wear, impingement wear (i.e. from non- intentional articulation), discoloration and pitting. Results. In each case, the middle M-M zones showed more damage features compared with peripheral MoP zones. Brown discoloration, presumably due to tribofilm deposits, was the predominant M-M area feature, particularly at the junction between the MoP and M-M zones. Higher magnification showed areas of polishing underlying the discoloration, suggesting repetitive removal of the surface metal and re-deposition of tribofilms (Fig 2B). 9 cases demonstrated reflective patches resembling “thumbprint” or “fish scale” markings, which, under higher magnification, showed signs of scratching and grooving in a radial pattern (Figs 2D, 3A). Pits were occasionally present but appeared to be from third-body damage as signs of corrosion were absent. Features that resembled carbides, sometimes with associated “comet” patterns of scratching were apparent under higher magnification in some areas. The MoP zones showed variable scratching, abrasion and wear polishing. The MoP to M-M junctional areas were demarcated by a distinct band corresponding, in some cases, to a narrow wear groove or gouge. 3 axles showed evidence of severe impingement wear on one proximal end. Discussion. This study of retrieved axle components demonstrated varying types of surface wear damage but no clear evidence of corrosion. This is presumably because these parts are in nearly constant motion during gait. Third-body damage may have resulted from the breakdown of surface carbides, leading to scratching, abrasion and wear polishing under high contact stress. Severe impingement wear presumably occurred after catastrophic damage to the polyethylene bushings, allowing eccentric loading and extensive metal wear. The components were revised for a range of clinical reasons including aseptic loosening and the need to expand the prosthesis during growth. With the exception of the few cases with severe impingement, it is unlikely that the wear features seen here contributed to the need for revision. While it was reassuring that corrosion was not a prominent feature of these modular M-M articulations, retrieval analysis of DFR components should be continued to confirm this finding, better document the in vivo wear processes and point to design features that might be improved for future patients. For any figures or tables, please contact the authors directly

Two big problems exist with the all polyethylene cemented tibial component; the polyethylene and the cement. The polyethylene is too weak and flexible to bear high tibial load, so it deforms and loosens. The interface stresses are too high when two flexible structures are poorly bonded and heavily loaded. Modularity between the polyethylene tibial component and the metal-backed tray was introduced in the mid-80's for versatility and to facilitate screw fixation for cementless implants. These designs allow exchange of various polyethylene thicknesses, and aids the addition of stems and wedges. Other advantages include the reduction of inventory, and the potential for isolated tibial polyethylene exchanges as a simpler revision procedure. Several studies have documented the high failure rate of isolated polyethylene exchange procedures, because technical problems related to the original components are left uncorrected. However, revision for wear is the simplest revision ever!. Since the late 1980's the phenomena of polyethylene wear and osteolysis have been observed much more frequently when compared with earlier eras. The reasons for this increased prevalence of synovitis, progressive osteolysis, and severe polyethylene wear remain unclear. There is some association with the widespread use of both cementless and cemented modular tibial designs. Improved polyethylene attachment is the answer even if a screw, a wire, or a pin is needed. Do not abandon the modular tibia

Introduction. Titanium nitride (TiN) coatings are used in total hip arthroplasty to reduce friction of bearing couples or to decrease the allergic potential of orthopaedic alloys. Little is known about performance of currently manufactured implants, since only few retrieval studies were performed, furthermore they included a small number of implants manufactured over 15 years ago. Aim of study. To examine wear and degradation of retrieved TiN coated femoral heads articulating with ultra-high molecular weight polyethylene (UHMWPE). Methods. We included eight femoral heads with a made od TiAl6V4 alloy and coated with TiN using Physical Vapour Deposition (PVD). All heads (28 and 32 mm) were retrieved after at least 12 months of use (range 12–56). The reason for revision was aseptic loosening in 6 cases, septic loosening in one case and recurrent dislocations (five episodes) in one uncemented prosthesis. One unused head was included as reference sample. All implants were evaluated with light microscopy, Scanning Electron Microscopy (SEM) with Energy-Dispersive X-ray Spectroscopy (EDS). 30 SEM images from each implant were digitally analysed using ImageJ software to compare damage in loaded and non weight-bearing parts of the heads. Results. Studies with light microscopy revealed severe damage to the dislocated femoral head, with multiple metallic scratches. SEM studies indicated presence of multiple scratches and pinholes with a diameter of 1–10 µm (Fig1a,b,). Residue from the manufacturing process was present in all implants in form of pure Ti droplets found in round voids. In all implants we found irregular areas (diam. 20–50 µm, Fig 1c,d) where the coating was delaminated from the substrate metal with cracks arising from coating defects (Fig1e-h). Some of these debonded fragments were embedded into the PVD layer in weight-bearing parts of all heads. In one head, which was subjected to dislocations we observed deposits of titanium alloy from the acetabular shell (Fig 2a,b). The deposits were accompanied by large patches of delaminated coating as well as multiple cracks (Fig 2c,d). Small fragments of the acetabular titanium alloy damaged the coating in third body mechanism. Surprisingly in three implants we EDS analysis revealed similar spheres (diam. 1–10 µm) containing Niobium (Nb), although this element is not a part of any of the components used in the implants(Fig 2e,f). Interestingly presence of Nb droplets were associated with a higher number of other defect in these heads both in weight-baring and non weight-bearing parts of the heads suggesting inferior coating quality in these cases (Fig 2 g,h; Fig3, cases H2,H5,H8). Conclusions. Compared to previous studies we did not observe severe wear or the coating, however we observed some degradation of the film in vivo. Our results indicate that dislocation can lead to severe failure of the coating in vivo. Moreover presence of Nb residues and coexisting defects in some implants suggests inferior coating quality in these implants and indicates the need for strict monitoring of the production process. This study was funded by a grant from the National Science Centre nr 2012/05/D/NZ5/01840

Introduction. Due to the predictability of outcomes achieved with reverse shoulder arthroplasty (rTSA), rTSA is increasingly being used in patients where glenoid fixation is compromised due to presence of glenoid wear. There are various methods to achieve glenoid fixation in patients with glenoid wear, including the use of bone grafting behind the glenoid baseplate or the use of augmented glenoid baseplates. This clinical study quantifies clinical outcomes achieved using both techniques in patients with severe glenoid wear at 2 years minimum follow-up. Methods. 80 patients (mean age: 71.6yrs) with 2 years minimum follow-up were treated by 7 fellowship trained orthopaedic surgeons using rTSA with bone graft behind the baseplate or rTSA with an augmented glenoid baseplate in patients with severe posterior glenoid wear. 39 rTSA patients (14 female, avg: 73.1 yrs; 25 male, avg: 71.5 yrs) received an augmented glenoid (cohort composed of 24 patients with an 8° posterior augment baseplate and 15 patients with a 10° superior augment baseplate) for treatment of CTA, RCT, and OA with a medially eroded scapula. 41 rTSA patients (27 female, avg: 73.0 yrs; 14 male, avg: 66.9 yrs) received glenoid bone graft (cohort composed of 5 patients with allograft and 36 patients with autograft) for treatment of CTA, RCT, and OA with a medially eroded scapula. Outcomes were scored using SST, UCLA, ASES, Constant, and SPADI metrics; active abduction, forward flexion, and internal/external rotation were also measured to quantify function. Average follow-up was 31.2 months (augment 28.3; graft 34.1). A two-tailed, unpaired t-test identified differences (p<0.05) in pre-operative, post-operative, and pre-to-post improvements. Results. A comparison of pre-operative, post-operative, and pre-to-post improvement in outcomes are presented in Tables 1–3, respectively. No difference was noted in pre-operative, post-operative, and pre-to-post improvement in outcomes between cohorts. The augmented glenoid baseplate rTSA cohort had 0 complications for a complication rate of 0%; whereas, the rTSA glenoid bone graft cohort had 6 complications (including 2 glenoid loosenings/graft failures) for a complication rate of 14.6%. Additionally, radiographic follow-up information was available for 30 of 39 augmented baseplate patients (76.9%) and 27 of 41 bone graft patients (65.9%); where the augmented baseplate rTSA cohort had a scapular notching rate of 10.0% with an average scapular notching grade of 0.1; whereas, the rTSA glenoid bone graft cohort had a scapular notching rate of 18.5% with an average scapular notching grade of 0.19. Conclusions. These results demonstrate positive outcomes can be achieved at 2 years minimum follow-up in patients with severe glenoid wear using either augmented glenoid baseplates or bone graft behind the glenoid baseplate with rTSA. While no statistical difference was noted between pre-operative, post-operative, and pre-to-post improvement in outcomes between rTSA cohorts, a substantial difference in the complication rate was noted between cohorts which may factor into the surgeon's decision of the choice of treatment technique for these patients. Additional and longer-term follow-up is needed to confirm these outcomes and trends

One of serious issues in total hip arthroplasty (THA) is the osteolysis which results in aseptic loosening caused by the wear particles from a polyethylene (PE) acetabular cup. In addition, oxidation degradation of PE cup resulting in the fracture or the severe wear caused by the reduction of mechanical properties in vivo is also the issue. The oxidation degradation is considered to be induced by residual free radicals generated by gamma-ray irradiation for cross-linking to reduce wear or for sterilization. In this study, (1) wear property, (2) oxidation degradation of retrieved PE and highly cross-linked PE (CLPE) cups against alumina ceramic femoral heads, and (3) the correlation between those properties were evaluated. The radiographic wear of six conventional PE cups with the mean follow-up of 19.1–23.3 years and 60 CLPE cups with the mean follow-up of 3.1–9.1 years were measured by a non-radiostereometric analysis method (Vectorworks. ®. 10.5 software package). As a retrieval analysis, 26 retrieved acetabular cups were evaluated; 16 cups were ethylene oxide gas-sterilized conventional PE cups with clinical use for 16.0–24.9 years and 10 cups were gamma-ray-sterilized CLPE cups with clinical use for 0.9–6.7 years. The linear and the volumetric wear were measured using a three-dimensional (3D) coordinate measurement machine. The shapes of unworn and worn surfaces with 15- and 30-point intervals, respectively, were measured. Oxidation degradation of the surface, sub-surface and inner for both worn and unworn parts of the retrieved cups was measured using a Fourier-transform infrared (FT-IR) spectroscopy. Oxidation indices were calculated using the peak at 1740 cm. −1. and 1370 cm. −1. according to ASTM F2012. In the radiographic analysis, the linear wear rate of CLPE cups was significantly lower than that of conventional PE cups [Fig. 1]. In the retrieval analysis, the linear wear rate of CLPE cups (mean: 0.07 mm/year) showed a 51% reduction (p = 0.002) compared to conventional PE cups (mean: 0.14 mm/year) [Fig. 2]. The retrieval and the radiographic analysis for both conventional PE and CLPE cups showed similar results (p = 0.7 and 0.1, respectively). Maximum oxidation indices for CLPE cups were similar to those of conventional PE cups regardless of the difference of clinical duration [Fig. 3]. This result is different from in vivo wear, which increases as the clinical duration. For both conventional PE and CLPE cups, the oxidation indices of subsurface were higher than those for surface. The worn parts showed higher oxidation indices than those for unworn parts. From the results, even when the free radicals were so few or absent, the oxidation degradation would be induced in vivo. In conclusion, the wear resistance for CLPE cups was greater than that for conventional PE cups from both radiographic and retrieval analyses. The in vivo oxidation degradation might not be caused by only residual free radicals. It was found that oxidation degradation of PE cups when used with alumina ceramic femoral heads is not correlated to their wear properties

Purpose. In an effort to increase the durability of cemented total hip arthroplasties (THA), femoral stems were precoated using polymethlymethacrylate (PMMA). One such design is Harris precoat plus and centralign design (Zimmer, Warsaw, Indiana). The reports on these particular designs are variable, ranging from good survival to early failures, studied over short to medium term. Early failures have been attributed, most of the time to debonding at cement-bone interface. In view of lack of long term and variable results, we reviewed the results of primary hybrid THA performed during October 1990 to December 1995, using a PMMA coated, cemented femoral prosthesis and contemporary cementing techniques. Materials and Methods. 121 patients (136 hips) underwent primary THA using one of the precoated femoral stems during the study period. Thirty-five patients (36 hips) died and 23 patients (23 hips) were lost to follow-up due to some reasons. Two hips (2 patients) were revised for postoperative infection and hence, not included in study. Collectively, 75 hips (61 patients) were available for clinical and radiological reviews until the last follow-up, with an average follow-up period of 15.5 years (range, 14 to 18.3 years). The average age of the patients at the time of the index surgery was 53.6 years (range, 24 to 82 years). There were 43 males (55 hips) and 18 females (20 hips). Acetabular components used in these 75 hips were Harris Galante porous (HGP) cups in 69 hips and CLS Expansion cup (Protek, AG, Bern) in six hips. The mean age of 61 patients (75 hips) who were available for latest follow-up at December 2009, was 46 years (range, 22-65 years). Third generation cementing techniques and distal cement plug but no centralizer was used in all cases. All surgeries were performed by same surgeon at a single institute. Results. 23 femoral stems were revised, 20 for aseptic loosening (8 Precoat plus and 12 Centralign) and 3 for periprosthetic fracture with loosening (1 Precoat plus and 2 Centralign). The cementing of the femoral stem was grade A in 29 hips (39%), grade B in 16 (21%), C1 in 6 (8%) and grade C2 in 24 (32%). 21 of 24 hips which showed definitive loosening in radiogram had had cement grade C2 cementing. There were 22 acetabular revisions. 11 hips underwent isolated liner exchange for severe wear and osteolysis and in remaining 11 hips, complete acetabular component revision was performed. Indications for acetabular component revisions were aseptic loosening in five, severe lysis in four, extensive wear and metallosis in one, and liner dissociation in one. In one hip, with a fractured acetabular component due to severe pelvic bone defect, both the components were revised. Conclusion. Our results suggest that an early failure of the precoated femoral stem was mainly precipitated due to insufficient cementing technique (a thin cement mantle). Inherent flaws of the stem design may also accelerate the mechanism of failure

Two big problems exist with the all-polyethylene cemented tibial component; the polyethylene and the cement. The polyethylene is too weak and flexible to bear high tibial load, so it deforms and loosens. The interface stresses are too high when two flexible structures are poorly bonded and heavily loaded. Modularity between the polyethylene tibial component and the metal-backed tray was introduced in the mid-80's for versatility and to facilitate screw fixation for cementless implants. These designs allow exchange of various polyethylene thicknesses, and aids the addition of stems and wedges. Other advantages include the reduction of inventory, and the potential for isolated tibial polyethylene exchanges as a simpler revision procedure. Several studies have documented the high failure rate of isolated polyethylene exchange procedures, because technical problems related to the original components are left uncorrected. However, revision for wear is the simplest revision ever!. Since the late 1980's the phenomena of polyethylene wear and osteolysis has been observed much more frequently when compared with earlier eras. The reasons for this increased prevalence of synovitis, progressive osteolysis, and severe polyethylene wear remain unclear. There is some association with the widespread use of both cementless and cemented modular tibial designs. Improved polyethylene attachment is the answer even if a screw, a wire, or a pin is needed. Do not abandon the module tibia

Testing wear durability of UHMWPE joint replacement bearings under abrasive conditions (mimicking in vivo conditions when metallic components become scratched from bone or cement debris) is useful in screening new bearing materials or alternative processing methods. Adding third body particle debris in testing brings the complications of minimal (if any) increase in wear with particles lodging into the plastic bearings potentially causing unknown errors for gravimetric wear measurements. Alternatively, testing those bearings against already scratched metallic components may provide a cleaner route without such complications. This requires a method to reproducibly create scratches resembling the damage seen on retrievals. This study introduces such a method, and investigates wear of UHMWPE bearings against metallic femoral hip components that have been intentionally scratched. In this technique, femoral hip heads were pressed and sunk into a bed of abrasive beads under a known load (712N, one body weight), and this created longitudinal scratches. Latitudinal scratches were generated by rotating the sunken femoral heads ± 90° about their polar axis while under the same load. This process (pressing into the abrasive beads and then turning ± 90°) was repeated 10 times on each femoral component which resulted in thousands of random scratch patterns, but with statistically repeatable overall severity and similar visually to retrievals (Fig. 1). We then evaluated the technique through a hip wear study. Twelve UHMWPE liners (40 mm I.D.) were tested against CoCrMo femoral heads on a 12-station hip simulator (AMTI). Liners were three materials: a) Three conventional (GUR1020, gamma-sterilized 3.5 Mrad), b) Three highly cross-linked (HXL) (GUR1020, 10 Mrad, annealed, EtO-sterilized, artificially aged), and c) Six HXL w/vitamin-E (GUR1020, 12 Mrad, annealed, EtO-sterilized, aged). The test comprised three phases. Phase-I: standard clean (non-abrasive, non-scratched) test for 5 Mc; Phase-II: Pulverized PMMA was added to serum at 700 mg/L (to introduce abrasive conditions); however, effects were minimal after 2 Mc (7 Mc total). Phase-III: Femoral heads were scratched using our method. Phase-III lasted for 1 Mc, for a testing total of 8 Mc (ISO-14242-1 waveforms). All specimens were lubricated with bovine serum (37°C, 30g/L protein). Plastic liners were cleaned and weighed at standard intervals, and wear was corrected with active loaded soak controls. The wear results are shown in Fig. 2. The conventional liners showed the highest wear (Phase-I: 55.7 ± 3.00 mg/Mc, Phase-II: 49.2 ± 0.520 mg/Mc, Phase-III: 124 ± 28.9 mg/Mc) while HXL liners displayed much lower wear (Phase-I: 2.58 ± 0.969 mg/Mc; Phase-II: 4.93 ± 1.22 mg/Mc; Phase-III: 9.92 ± 4.64 mg/Mc). Vitamin-E HXL liners also showed very low wear (Phase-I: 5.97 ± 0.50 mg/Mc, Phase-II: 8.89 ± 1.40 mg/Mc, Phase-III: 11.9 ± 2.70 mg/Mc). Addition of the PMMA powder during Phase-II increased liner wear, but the surfaces did not appear damaged like retrievals. Wear rates between Phase-I and Phase-III doubled due to scratching the femoral heads for all material types, a statistically significant increase (p < 0.05). Our results confirm that the scratching procedure successfully created a severe wear situation for the bearings. Future work will involve abrasive testing on knee components to determine if the method is successful there too

Background. Use of a baseplate with a smaller diameter in reverse shoulder arthroplasty has been recommended, especially in patients with a small glenoid or insufficient bony stock due to severe glenoid wear. However, effect of a smaller baseplate on stability of the glenoid component has not been evaluated. The purpose of this study was to determine whether a smaller baseplate (25 mm) is beneficial to the initial primary stability of the glenoid component compared to that with a baseplate of a commonly used size (29 mm) by finite element analysis. Methods. Computed tomography (CT) scans of fourteen scapulae were acquired from cadavers with no apparent deformity or degenerative change. Glenoid diameter corresponding to the diameter of the inferior circle of glenoid was measured using a caliper and classified into the small and large glenoid groups based on 25mm diameter. CT slices were used to construct 3-dimensional models with Mimics (Materialise, Leuven, Belgium). A corresponding 3D Tornier Aequalis® Reversed Shoulder prosthesis model was generated by laser scanning (Rexcan 3D Laser Scanner, Solutionix, Seoul, Korea). Glenoid components with 25mm and 28mm diameter of the baseplate were implanted into the scapular of small and large glenoid group, respectively. Finite element models were constructed using Hypermesh 11.0 (Altair Engineering, Troy, MI, USA) and a reverse engineering program (Rapidform 3D Systems, Inc., Rock Hill, SC, USA). Abaqus 6.10 (Dassault Systemes, Waltham, MA) was used to simulate 30. o. , 60. o. , and 90. o. glenohumeral abduction in the scapular plane. Single axial loads of 686N (1 BW) at angles of 30. o. , 60. o. , and 90. o. abduction were applied to the center of the glenosphere parallel to the long axis of the humeral stem. Relative micromotion at the middle and inferior thirds bone–glenoid component interface, and distribution of bone stress under the glenoid component and around the screws were analyzed. Wilcoxon's rank-sum test was used for statistical comparison and p < 0.05 was considered as a minimum level of statistical significance. Results. In small glenoid group, micromotion at the middle and inferior thirds of the glenoid-glenosphere interface at angles of 30. o. and 60. o. abduction were significantly greater in the 29mm baseplate than in the 25mm baseplate. There was no significant difference in micromotion at angle of 90. o. abduction between 25mm and 29mm baseplate. In large glenoid group, there was no statistically significant difference in micromotion between 25mm and 29mm baseplate at all angles of abduction. In small glenoid group, maximum bone stress was measured at the point of cortical engagement of the inferior screw and was statistically greater in the 29mm baseplate than in the 25mm baseplate. In large glenoid group, there was no statistically significant difference of maximum bone stress around the inferior screw between 25mm and 29mm baseplates. Conclusions. Use of a baseplate with a smaller diameter (25 mm) in reverse shoulder arthroplasty is suitable for improving the primary stability of the glenoid component, especially in small glenoid

Two big problems exist with the all-polyethylene cemented tibial component; the polyethylene and the cement. The polyethylene is too weak and flexible to bear tibial load, so it deforms and loosens. The interface stresses are too high when two flexible structures are poorly bonded and heavily loaded. Modularity between the polyethylene tibial component and the metal-backed tray was introduced in the mid-1980s for versatility and to facilitate screw fixation for cementless implants. These designs allow exchange of various polyethylene thicknesses, and aid the addition of stems and wedges. Other advantages include the reduction of inventory, and the potential for isolated tibial polyethylene exchanges as a simpler revision procedure. Several studies have documented the high failure rate of isolated polyethylene exchange procedures, because technical problems related to the original components are left uncorrected. However, revision for wear is the simplest revision ever!. Since the late 1980s the phenomena of polyethylene wear and osteolysis have been observed much more frequently when compared with earlier eras. The reasons for this increased prevalence of synovitis, progressive osteolysis, and severe polyethylene wear remain unclear. There is some association with the widespread use of both cementless and cemented modular tibial designs. Improved polyethylene attachment is the answer even if a screw, a wire, or a pin is needed. Do not abandon the modular tibia on any patient

Total knee replacement (TKR) is one of the most successful procedures in orthopaedic surgery. Although originally limited to more elderly and less active individuals, the inclusion criteria for TKR have changed, with ever younger, more active and heavier patients receiving TKR. Currently, wear debris related osteolysis and associated prosthetic loosening are major modes of failure for TKR implants of all designs. Initially, tibial components were cemented all polyethylene monoblock constructs. Subsequent long-term follow-up studies of these implants have demonstrated excellent durability in survivorship studies out to twenty years. Aseptic loosening of the tibial component was one of the main causes of failure in these implants. Cemented metal-backed nonmodular tibial components were subsequently introduced to allow for improved tibial load distribution and to protect osteoporotic bone. Long-term studies have established that many one-piece nonmodular tibial components have maintained excellent durability. Eventually, modularity between the polyethylene tibial component and the metal-backed tray was introduced in the mid-80s mainly to facilitate screw fixation for cementless implants. These designs also provided intraoperative versatility by allowing interchange of various polyethylene thicknesses, and to also aid the addition of stems and wedges. Other advantages included the reduction of inventory, and the potential for isolated tibial polyethylene exchanges as a simpler revision procedure. However, several studies have documented the high failure rate of isolated polyethylene exchange procedures, probably because technical problems related to the original components are left uncorrected. Since the late 1980s, the phenomena of polyethylene wear and osteolysis have been observed much more frequently when compared with earlier eras. The reasons for this increased prevalence of synovitis, progressive osteolysis, and severe polyethylene wear remain unclear, but there is no question that it was associated with the widespread use of both cementless and cemented modular tibial designs. Mayo Data. The study population included 10,601 adult patients with 14,524 primary TKA procedures performed at our institution between 1/1/1988 and 12/31/2005. Mean age was 68.7 years and 55% were female. Overall revision rates and revisions for loosening, wear/osteolysis were compared across different designs. Over an average 9 year follow-up, a total of 865 revisions, including 252 tibia revisions were performed, corresponding to overall survival of 89% (Confidence intervals (CI): 88%, 90%) at 15 years. In comparison to metal modular designs, risk of tibial revision was significantly lower with all-poly tibias (HR 0.3, 95% CI: 0.2, 0.5). Overall, posterior cruciate-retaining designs performed better than the posterior-stabilised designs (p=0.002). With any revision as the endpoint, there were no significant differences across the 18 designs examined. Similarly, there were no significant differences across the 18 designs when we considered revisions for aseptic loosening, wear, and osteolysis. Among patient characteristics, male gender, younger age, and higher BMI were all significantly associated with higher risk of revisions (p<0.008). Summary. Available data support the use of nonmodular tibial designs in TKA in order to prevent or reduce the chance of backside wear, third body particles from resulting metallic debris and associated polyethylene induced osteolysis. In all patients, (not just older individuals) use of an all polyethylene tibial component is an attractive and more cost effective alternative, and is associated with the best survivorship and lowest risk of revision

Introduction. Posterior glenoid wear is common with glenohumeral osteoarthritis. To correct posterior wear, surgeons may eccentrically ream the anterior glenoid to restore version. However, eccentric reaming undermines prosthesis support by removing unworn anterior glenoid bone, compromises cement fixation by increasing the likelihood of peg perforation, and medializes the joint line which has implications on joint stability. To conserve bone and preserve the joint line when correcting glenoid version, manufacturers have developed posterior augment glenoids for aTSA and rTSA applications. This clinical study quantifies outcomes achieved using posteriorly augmented aTSA/rTSA glenoid implants in patients with severe posterior glenoid wear at 2 years minimum follow-up. Methods. 47 patients (mean age: 68.7yrs) with 2 years minimum follow-up were treated by 5 fellowship trained orthopaedic surgeons using either 8° posteriorly augmented aTSA/rTSA glenoid components in patients with severe posterior glenoid wear. 24 aTSA patients received posteriorly augmented glenoids (65.8 yrs; 7F/17M) for OA and 23 rTSA patients received posteriorly augmented glenoids (71.8 yrs; 9F/14M) for treatment of CTA and OA. Outcomes were scored using SST, UCLA, ASES, Constant, and SPADI metrics; active abduction, forward flexion, and external rotation were also measured to quantify function. Average follow-up was 27.5 months (aTSA 29.4; rTSA 25.5). A two-tailed, unpaired t-test identified differences (p<0.05) in pre-operative, post-operative, and pre-to-post improvements. Results. A comparison of pre-operative, post-operative, and pre-to-post improvement in outcomes are presented in Tables 1–3, respectively. As described in Table 1, pre-operative outcomes were similar for patients receiving posterior augment aTSA and posterior augment rTSA implants, with only active abduction being significantly less in rTSA patients. Additionally, rTSA patients were noted to be significantly older (p=0.0434) and have significantly longer follow-up (p=0.0358) though no difference was noted in mean patient height, weight, or BMI between cohorts. As described in Table 2, at 2 years minimum follow-up posterior augment aTSA patients were associated with significantly greater SST scores and also had significantly more active abduction and active external rotation than posterior augment rTSA patients. However, as described in Table 3, no significant difference was observed in pre-to-post improvement of outcome scoring metrics and only improvement in active external rotation was observed to be significantly different between the two cohorts. No complications were reported for either posterior augment implant cohort. Conclusions. These results demonstrate positive outcomes can be achieved at 2 years minimum follow-up in patients with severe posterior wear using either posteriorly augmented aTSA/rTSA glenoid implants. While relative differences in outcomes were noted, these mean differences are expected due to differing indications and associated differences in rotator cuff status. Due to the aforementioned concerns of aseptic glenoid loosening in patients with severe posterior glenoid wear, some have recommend treating patients with posterior glenoid wear using only rTSA regardless of the status of the patient's rotator cuff. The results of this study demonstrate that patients with posterior glenoid wear and a functioning rotator cuff can be successfully treated with posterior augmented aTSA as well. Additional and longer-term follow-up is needed to confirm these positive outcomes

Total knee replacement (TKR) is one of the most successful procedures in orthopaedic surgery. Although originally limited to more elderly and less active individuals, the inclusion criteria for TKR have changed, with ever younger, more active and heavier patients receiving TKR. Initially, tibial components were cemented all-polyethylene monoblock constructs. Subsequent long-term follow-up studies of these implants have demonstrated excellent durability in survivorship studies out to 20 years. Aseptic loosening of the tibial component was one of the main causes of failure in these implants. Polyethylene wear with osteolysis around well-fixed implants was rarely (if ever) observed. Cemented metal-backed nonmodular tibial components were subsequently introduced to allow for improved tibial load distribution and to protect osteoporotic bone. Long-term studies have established that many one-piece nonmodular tibial components have maintained excellent durability. Eventually, modularity between the polyethylene tibial component and the metal-backed tray was introduced in the mid-80s mainly to facilitate screw fixation for cementless implants. These designs also provided intra-operative versatility by allowing interchange of various polyethylene thicknesses, and also aided the addition of stems and wedges. Other advantages included the reduction of inventory, and the potential for isolated tibial polyethylene exchanges. Since the late 1980's, the phenomena of polyethylene wear and osteolysis have been observed much more frequently when compared with earlier eras. The reasons for this increased prevalence of synovitis, progressive osteolysis, and severe polyethylene wear remain unclear, but there is no question that it was associated with the widespread use of both cementless and cemented modular tibial designs. Mayo Data: Modular versus All Polyethylene Tibial Components in Primary TKA: The study population included 10,601 adult (>18 years) patients with 14,524 primary TKR procedures performed at our institution between 1/1/1988 and 12/31/2005. Mean age was 68.7 years and 55% were female. Overall revision rates and revisions for loosening, wear/osteolysis were compared across different designs using Cox proportional hazards regression models adjusting for age, sex, calendar year and body mass index (BMI). Over an average 9 years follow-up, a total of 865 revisions, including 252 tibia revisions were performed, corresponding to overall survival of 89% (Confidence intervals (CI): 88%, 90%) at 15 years. In comparison to metal modular designs, risk of tibial revision was significantly lower with all-poly tibias (HR 0.3, 95% CI: 0.2, 0.5). Overall, posterior cruciate-retaining (CR) designs performed better than the posterior-stabilised (PS) designs (p=0.002). With any revision as the endpoint, there were no significant differences across the 18 designs examined. Similarly, there were no significant differences across the 18 designs when we considered revisions for aseptic loosening, wear, and osteolysis. Among patient characteristics, male gender, younger age, higher BMI were all significantly associated with higher risk of revisions (p<0.008). Available data support the use of nonmodular tibial designs in TKR in order to prevent or reduce the chance of backside wear, third body particles from resulting metallic debris and associated polyethylene induced osteolysis. In all patients, (not just older individuals) use of an all polyethylene tibial component is an attractive and more cost effective alternative, and is associated with the best survivorship and lowest risk of revision

Total knee replacement is one of the most successful procedures in orthopaedic surgery. Although originally limited to more elderly and less active individuals, the inclusion criteria for TKA have changed, with ever younger, more active and heavier patients receiving TKA. Currently, wear debris related osteolysis and associated prosthetic loosening are major modes of failure for TKA implants of all designs. Initially, tibial components were cemented all-polyethylene monoblock constructs. Subsequent long-term follow up studies of these implants have demonstrated excellent durability in survivorship studies out to twenty years. Aseptic loosening of the tibial component was one of the main causes of failure in these implants. Polyethylene wear with osteolysis around well fixed implants was rarely (if ever) observed. Cemented metal-backed nonmodular tibial components were subsequently introduced to allow for improved tibial load distribution and to protect osteoporotic bone. Long-term studies have established that many one-piece nonmodular tibial components have maintained excellent durability. Eventually, modularity between the polyethylene tibial component and the metal-backed tray was introduced in the mid-80s mainly to facilitate screw fixation for cementless implants. These designs also provided intra-operative versatility by allowing interchange of various polyethylene thicknesses, and to also aid the addition of stems and wedges. Other advantages included the reduction of inventory, and the potential for isolated tibial polyethylene exchanges as a simpler revision procedure. However, since the late 1980's, the phenomena of polyethylene wear and osteolysis have been observed much more frequently when compared with earlier eras. The reasons for this increased prevalence of synovitis, progressive osteolysis, and severe polyethylene wear remain unclear, but it is likely associated with the widespread use of both cementless and cemented modular tibial designs. Backside wear between the metal tray and polyethylene has been implicated. Recent RSA studies comparing fixation of all-polyethylene to modular components has shown that their RSA migration patterns are superior and fixation is in fact better with the all-polyethylene construct. Further, in a recent meta-analysis, all-polyethylene components were equivalent to metal-backed components regarding revision rates and clinical scores. The promise of modular tibial components affording a simple liner exchange to revise a knee has not borne out in the literature. Several studies have revealed that the effectiveness of isolated tibial insert exchange in revision TKR is of limited value. Isolated tibial insert exchange led to a surprisingly high rate of early failure. Tibial insert exchange as an isolated method of total knee revision should therefore be undertaken with caution even in circumstances for which the modular insert was designed and believed to be of greatest value. Because of the modularity, extra materials, and extra processing, modular tibial components are significantly more expensive than all-polyethylene components

Total knee replacement is one of the most successful procedures in orthopaedic surgery. Although originally limited to more elderly and less active individuals, the inclusion criteria have changed, with ever younger, more active and heavier patients receiving TKA. Currently, wear debris related osteolysis and associated prosthetic loosening are major modes of failure for TKA implants of all designs. Initially, tibial components were cemented all polyethylene monoblock constructs. Subsequent long-term follow-up studies of these implants have demonstrated excellent durability in survivorship studies out to twenty years. Aseptic loosening of the tibial component was one of the main causes of failure in these implants. Polyethylene wear with osteolysis around well fixed implants was rarely (if ever) observed. Cemented metal-backed nonmodular tibial components were subsequently introduced to allow for improved tibial load distribution and to protect osteoporotic bone. Long-term studies have established that many one-piece nonmodular tibial components have maintained excellent durability. Eventually, modularity between the polyethylene tibial component and the metal-backed tray was introduced in the mid-80s mainly to facilitate screw fixation for cementless implants. These designs also provided intraoperative versatility by allowing interchange of various polyethylene thicknesses, and also aided the addition of stems and wedges. Since the late 1980's, the phenomena of polyethylene wear and osteolysis have been observed much more frequently when compared with earlier eras. The reasons for this increased prevalence of synovitis, progressive osteolysis, and severe polyethylene wear remain unclear, but there is no question that it was associated with the widespread use of both cementless and cemented modular tibial designs. Mayo Data: Modular versus All Polyethylene Tibial Components in Primary TKA. The study population included 10,601 adult (>18 years) patients with 14,524 primary TKA procedures performed at our institution between 1/1/1988 and 12/31/2005. Mean age was 68.7 years and 55% were female. Overall revision rates and revisions for loosening, wear/osteolysis were compared across different designs using Cox proportional hazards regression models adjusting for age, sex, calendar year and body mass index (BMI). Over an average 9 years follow-up, a total of 865 revisions, including 252 tibia revisions were performed, corresponding to overall survival of 89% (Confidence intervals (CI): 88%, 90%) at 15 years. In comparison to metal modular designs, risk of tibial revision was significantly lower with all-poly tibias (HR 0.3, 95% CI: 0.2, 0.5). Overall, posterior cruciate-retaining (CR) designs performed better than the posterior-stabilised (PS) designs (p=0.002). With any revision as the endpoint, there were no significant differences across the 18 designs examined. Similarly, there were no significant differences across the 18 designs when we considered revisions for aseptic loosening, wear, osteolysis. Among patient characteristics, male gender, younger age, higher BMI were all significantly associated with higher risk of revisions (p<0.008). Summary: Available data support the use of nonmodular tibial designs in TKA in order to prevent or reduce the chance of backside wear, third body particles from resulting metallic debris and associated polyethylene induced osteolysis. In all patients, (not just older individuals) use of an all polyethylene tibial component is an attractive and more cost effective alternative, and is associated with the best survivorship and lowest risk of revision

Revision of fractured ceramic-on-ceramic total hip replacements with a cobalt-chromium (CoCr) alloy-on-polyethylene articulation can facilitate metallosis and require further expensive revision surgery [1–3]. In the present study, a fifty-two year old male patient suffered from fatal cardiomyopathy after undergoing revision total hip arthroplasty. The patient had received a polyethylene-ceramic acetabular liner and a ceramic femoral head as his primary total hip replacement. The polyethylene-ceramic sandwich acetabular liner fractured in vivo after 58 months and the patient underwent his first revision surgery where he received a Vitamin E stabilized acetabular Polyethylene (PE) liner and a CoCr alloy femoral head with documented synovectomy at that time. After 15 months, the patient was admitted to hospital in cardiogenic shock, with retrieval of the bearing components. Before the second revision surgery, peak serum cobalt levels measured 6,521 μg/L, 78-times greater than serum cobalt levels of 83μg/L associated with cobalt poisoning [4]. Serum titanium levels found in the patient measured 17.5 μg/L) normal, healthy range 0–1.4 μg/L). The retrieved CoCr alloy femoral head had lost a total of 28.3g (24% or an estimated amount of 102 × 10. −9. wear particles (∼2 μm diameter) [1]) within 16 months of in vivo service. Despite initiating a cobalt chelating therapy, the patients' cardiac left ventricular ejection fraction remained reduced at 6%. This was followed by multi-organ failure, and ultimately the patient passed away shortly after being taken off life support. Embedded ceramic particles were found on the backside and articular surfaces of the Vitamin E-stabilized PE acetabular liner. Evidence of fretting wear on the titanium (Ti) alloy acetabular shell was present, possibly explaining the increased serum Ti levels. Scanning electron microscopy and energy dispersive X-ray analyses confirmed Ti alloy transfer on the embedded ceramic particles on the backside PE liner surface and CoCr alloy transfer on the embedded ceramic particles on the articular PE liner surface. A fractured ceramic-on-ceramic total hip replacement should not be revised to a CoCr alloy-on-polyethylene articulation irrespective of concurrent synovectomy [5] as it can cause severe, third-body wear to the CoCr alloy femoral head that can lead to metallosis with fatal, systemic consequences

There is a consensus that impingement, subluxation, and dislocation are major risks that can lead to failure in total hip arthroplasty (1). As well as producing edge-wear, such clinical events also may create additional loads of particulate debris (2). It has been suggested that the release of metal debris with collateral damage on metal-on-metal (MOM) bearings creates a particularly severe abrasive wear, hitherto not understood, and recently termed ‘micro-grooving’ (3,4). Perhaps related to this micro-grooving, large surface depressions have also been observed. These we labeled ‘Dongas’, from the South African term for a steep-sided gully created by erosion. The goal of this study was to examine Dongas found on retrieved MOM bearings and to correlate factors such as cause of revision, MOM diameter and Donga locations with respect to regions of normal and stripe wear. Our hypotheses were: (1) Dongas will be most visible in non-wear zones (NWZ) adjacent to the main-wear zone boundary (MWZ), (2) the 28 mm MOM, being inherently less stable compared to large-diameter MOM, will show a higher Donga frequency and (3) patients with subluxation or dislocation complaints will reveal a higher Donga frequency. Five cases with 28 mm MOM, five of 34–38 mm, and five of 50–56 mm diameter were studied (N = 15). The MWZ was measured in each MOM head and the number of NWZ and MWZ Dongas recorded. Bearing damage was examined using a white-light interferometer (Zygo; 5x lens). Dongas were mainly elliptical in shape, but sometimes highly irregular. They were commonly circumscribed by raised lips (Fig. 1). Donga “trails” were also found, appearing as a linear series of similar-sized Dongas (Fig. 2). Donga trails exhibited some variability with raised lips either lining only the opposite sides or circumscribing most of the perimeter. The Dongas were commonly found in NWZ, with less than 20% found in MWZ. For this set of 15 MOM bearings, large-diameter bearings showed the largest number of Dongas and the greatest frequency of Dongas resulted from either loose or migrating cups. The high occurrence of dongas in the non-wear zone (supporting hypothesis-1) may be a result of particles swept into the bearing interface (2,5). The size of the Dongas and their frequent association to local micro-grooves indicated that these were the impact sites of circulating particles. Such large surface depressions (40–200 μm) have not been described previously and may be unique to MOM bearings (3,4). The observation that Dongas were most prevalent in cases with loose or migrating cups left hypothesis-2 unsatisfied. The much higher incidence of Dongas in the large-diameter MOM was surprising and negated hypothesis-3. Overall these new data relating Dongas and micro-grooves gives new credence to a hitherto unsuspected 3. rd. -body abrasive wear mechanism due to repetitive subluxation or impingement

Introduction. The wrist arthroscopy has been performed since 1979. With the advances in technology and surgical expertise, wrist arthroscopy has become third commonest procedure after knee and shoulder joint. Wrist arthroscopy has become a gold standard for diagnosing TFCC pathologies and other intercarpal disorders. Our aim was to compare the clinical, MRI and arthroscopic findings while treating various wrist pathologies. Materials/Method. In retrospective trial, 30 patients (19 male and 11 female) with clinical evidence of wrist lesions were evaluated with MRI followed by wrist arthroscopy. The mean age of the patients at the time of outpatient appointment was 44 years with an average waiting time of 6.6 months. Inclusion criteria: all patients undergoing wrist surgery. Exclusion criteria: septic arthritis, acute distal radius fractures. Kappa analysis was used to compare the three methods of wrist pathology assessment. The total 30 patients were assessed for clinical findings, MRI report and corresponding arthroscopic findings. Results. According to the clinical findings, 22 patients (68% of all patients) were diagnosed with suspected TFCC injury. In 21 patients, the MRI showed TFCC tear (partial to complete) and this was confirmed by arthroscopy in 22 patients. There was a correlation of clinical, MRI and arthroscopy in detecting TFCC lesions in 95% cases. Sensitivity 93%, specificity 90%, positive predictive value 89% and negative predictive value 94%. The Scapho-lunate ligament tear was suspected in 8 (28% of all patients). In 6 patients, MRI showed scapho-lunate tear and this was confirmed by wrist arthroscopy in 10 patients. Correlation with wrist arthroscopy was 80%, sensitivity 94%, specificity 92%, positive predictive value 90% and negative predictive value 93%. 15 patients (50% of all patients) showed signs of moderate to severe cartilage wear and 12 patients had confirmation with MRI. Correlation with wrist arthroscopy was 75%, Sensitivity 90%, Specificity 91%, positive predictive value 89% with negative predictive value 92%. However clinical examination and MRI had poor correlation with wrist arthroscopy in diagnosing synovitis. Discussion. The MRI and wrist arthroscopy has fair correlation, though MRI sensitivity approaches that of arthroscopy, it cannot replace it at the moment. However, it is a potent additional tool for wrist diagnosis if intra-articular contrast is used. It can facilitate diagnosis and indications for surgery of the wrist. It may make arthroscopic and more invasive interventions for diagnostic purposes avoidable in future. Our results showed clinical examination is crucial for diagnosing wrist pathologies, MRI can be used as an adjunct but the wrist arthroscopy still remains the gold standard tool for diagnosis and therapeutic interventions