Aims.
Introduction. Maintaining posterior stability in total knee arthroplasty (TKA) may be achieved by using a posterior stabilized TKA, retaining and balancing the posterior cruciate ligament (PCL) using a traditional cruciate-retaining design (CR), or by increasing the
Bicruciate-stabilised total knee replacement (TKR) aims to restore normal kinematics by replicating the function of both cruciate ligaments. We performed a prospective, randomised controlled trial in which bicruciate- and posterior-stabilised TKRs were implanted in 13 and 15 osteo-arthritic knees, respectively. The mean age of the bicruciate-stabilised group was 63.9 years ( At near full extension during step-up, the bicruciate-stabilised TKR produced a higher mean PTA than the posterior-stabilised TKR, indicating that the bicruciate design at least partially restored the kinematic role of the anterior cruciate ligament. The bicruciate-stabilised TKR largely restored the pre-operative kinematics, whereas the posterior-stabilised TKR resulted in a consistently lower PTA at all activities. The PTA in the pre-operative knees was higher than in the control group during the step-up and at near full knee extension. Overall, both groups generated a more normal PTA than that seen in previous studies in high knee flexion. This suggested that both designs of TKR were more effective at replicating the kinematic role of the posterior cruciate ligament than those used in previous studies.
Objectives. Unicompartmental knee arthroplasty (UKA) is one surgical option for treating symptomatic medial osteoarthritis. Clinical studies have shown the functional benefits of UKA; however, the optimal alignment of the tibial component is still debated. The purpose of this study was to evaluate the effects of tibial coronal and
Aims. Porous metaphyseal cones can be used for fixation in revision total knee arthroplasty (rTKA) and complex TKAs. This metaphyseal fixation has led to some surgeons using shorter cemented stems instead of diaphyseal engaging cementless stems with a potential benefit of ease of obtaining proper alignment without being beholden to the diaphysis. The purpose of this study was to evaluate short term clinical and radiographic outcomes of a series of TKA cases performed using 3D-printed metaphyseal cones. Methods. A retrospective review of 86 rTKAs and nine complex primary TKAs, with an average age of 63.2 years (SD 8.2) and BMI of 34.0 kg/m. 2. (SD 8.7), in which metaphyseal cones were used for both femoral and tibial fixation were compared for their knee alignment based on the type of stem used. Overall, 22 knees had cementless stems on both sides, 52 had cemented stems on both sides, and 15 had mixed stems. Postoperative long-standing radiographs were evaluated for coronal and
Aims. Mid-level constraint designs for total knee arthroplasty (TKA) are intended to reduce coronal plane laxity. Our aims were to compare kinematics and ligament forces of the Zimmer Biomet Persona posterior-stabilized (PS) and mid-level designs in the coronal, sagittal, and axial planes under loads simulating clinical exams of the knee in a cadaver model. Methods. We performed TKA on eight cadaveric knees and loaded them using a robotic manipulator. We tested both PS and mid-level designs under loads simulating clinical exams via applied varus and valgus moments, internal-external (IE) rotation moments, and anteroposterior forces at 0°, 30°, and 90° of flexion. We measured the resulting tibiofemoral angulations and translations. We also quantified the forces carried by the medial and lateral collateral ligaments (MCL/LCL) via serial sectioning of these structures and use of the principle of superposition. Results. Mid-level inserts reduced varus angulations compared to PS inserts by a median of 0.4°, 0.9°, and 1.5° at 0°, 30°, and 90° of flexion, respectively, and reduced valgus angulations by a median of 0.3°, 1.0°, and 1.2° (p ≤ 0.027 for all comparisons). Mid-level inserts reduced net IE rotations by a median of 5.6°, 14.7°, and 17.5° at 0°, 30°, and 90°, respectively (p = 0.012). Mid-level inserts reduced anterior tibial translation only at 90° of flexion by a median of 3.0 millimetres (p = 0.036). With an applied varus moment, the mid-level insert decreased LCL force compared to the PS insert at all three flexion angles that were tested (p ≤ 0.036). In contrast, with a valgus moment the mid-level insert did not reduce MCL force. With an applied internal rotation moment, the mid-level insert decreased LCL force at 30° and 90° by a median of 25.7 N and 31.7 N, respectively (p = 0.017 and p = 0.012). With an external rotation moment, the mid-level insert decreased MCL force at 30° and 90° by a median of 45.7 N and 20.0 N, respectively (p ≤ 0.017 for all comparisons). With an applied anterior load, MCL and LCL forces showed no differences between the two inserts at 30° and 90° of flexion. Conclusion. The mid-level insert used in this study decreased coronal and axial plane laxities compared to the PS insert, but its stabilizing benefit in the
Introduction. Porous metaphyseal cones are increasingly used for fixation in revision total knee arthroplasty (RTKA). Both cemented shorter length stems and longer diaphyseal engaging stems are currently utilized with metaphyseal cones with no clear evidence of superiority. The purpose of this study was to evaluate our experience with 3D printed titanium metaphyseal cones with both short cemented and longer cementless stems from a clinical and radiographic perspective. Methods. In total 136 3D printed titanium metaphyseal cones were implanted. The mean patient age was 63 and 48% were female. The mean BMI was 33 and the mean ASA class was 2.5. There were 42 femoral cones in which 28 cemented and 14 cementless stems were utilized. There were 94 tibial cones in which 67 cemented and 27 cementless stems were utilized. The choice for stem fixation was surgeon dependent and in general cones were utilized for AORI type 2 and 3 bone defects on the femur and tibia. The most common fixation scenario was short cemented stems on both the femur and tibia followed by cemented stem fixation on the tibia and cementless fixation on the femur. Clinical data such as revision, complication, and PRO was collected at last follow-up (minimum follow-up 1 year). Radiographic analysis included cone bony ingrowth and coronal and sagittal alignment on long-standing radiographs. Descriptive statistics were used to compare demographics between patients who had malalignment (HKA beyond +/− 3 degrees and flexion/extension beyond +/− 3 degrees). Adjusted logistic regression models were run to assess malalignment risk by stem type. Results. Patient reported outcomes demonstrated modest improvements with Pre-op KOOS improving from 44 pre-op to 59 post -op and PF-CAT improving from 33 to 37 post-op. PROMIS pain scores decreased significantly from 54 to 44 post-op. 36% of patients had malalignment in either the coronal or
We conducted a meta-analysis, including randomised
controlled trials (RCTs) and cohort studies, to examine the effect
of patient-specific instruments (PSI) on radiological outcomes after
total knee replacement (TKR) including: mechanical axis alignment
and malalignment of the femoral and tibial components in the coronal,
sagittal and axial planes, at a threshold of >
3º from neutral.
Relative risks (RR) for malalignment were determined for all studies
and for RCTs and cohort studies separately. Of 325 studies initially identified, 16 met the eligibility criteria,
including eight RCTs and eight cohort studies. There was no significant
difference in the likelihood of mechanical axis malalignment with
PSI versus conventional TKR across all studies
(RR = 0.84, p = 0.304), in the RCTs (RR = 1.14, p = 0.445) or in
the cohort studies (RR = 0.70, p = 0.289). The results for the alignment
of the tibial component were significantly worse using PSI TKR than conventional
TKR in the coronal and
Aims. The aim of this study was to report patient and clinical outcomes following robotic-assisted total knee arthroplasty (RA-TKA) at multiple institutions with a minimum two-year follow-up. Methods. This was a multicentre registry study from October 2016 to June 2021 that included 861 primary RA-TKA patients who completed at least one pre- and postoperative patient-reported outcome measure (PROM) questionnaire, including Forgotten Joint Score (FJS), Knee Injury and Osteoarthritis Outcomes Score for Joint Replacement (KOOS JR), and pain out of 100 points. The mean age was 67 years (35 to 86), 452 were male (53%), mean BMI was 31.5 kg/m. 2. (19 to 58), and 553 (64%) cemented and 308 (36%) cementless implants. Results. There were significant improvements in PROMs over time between preoperative, one- to two-year, and > two-year follow-up, with a mean FJS of 17.5 (SD 18.2), 70.2 (SD 27.8), and 76.7 (SD 25.8; p < 0.001); mean KOOS JR of 51.6 (SD 11.5), 85.1 (SD 13.8), and 87.9 (SD 13.0; p < 0.001); and mean pain scores of 65.7 (SD 20.4), 13.0 (SD 19.1), and 11.3 (SD 19.9; p < 0.001), respectively. There were eight superficial infections (0.9%) and four revisions (0.5%). Conclusion. RA-TKA demonstrated consistent clinical results across multiple institutions with excellent PROMs that continued to improve over time. With the ability to achieve target alignment in the coronal, axial, and
Intra-articular resection of bone with soft-tissue balancing and total knee replacement (TKR) has been described for the treatment of patients with severe osteoarthritis of the knee associated with an ipsilateral malunited femoral fracture. However, the extent to which deformity in the
We scanned 25 left knees in healthy human subjects
using MRI. Multiplanar reconstruction software was used to take
measurements of the inferior and posterior facets of the femoral
condyles and the trochlea. A ‘basic circle’ can be defined which, in the
We have investigated the benefits of patient
specific instrument guides, applied to osteotomies around the knee. Single,
dual and triple planar osteotomies were performed on tibias or femurs
in 14 subjects. In all patients, a detailed pre-operative plan was
prepared based upon full leg standing radiographic and CT scan information.
The planned level of the osteotomy and open wedge resection was
relayed to the surgery by virtue of a patient specific guide developed
from the images. The mean deviation between the planned wedge angle
and the executed wedge angle was 0° (-1 to 1, . sd. 0.71)
in the coronal plane and 0.3°
(-0.9 to 3, . sd. 1.14) in the
Aims. This prospective randomised controlled trial was designed to
evaluate the outcome of both the MRI- and CT-based patient-specific
matched guides (PSG) from the same manufacturer. Patients and Methods. A total of 137 knees in 137 patients (50 men, 87 women) were
included, 67 in the MRI- and 70 in the CT-based PSG group. Their
mean age was 68.4 years (47.0 to 88.9). Outcome was expressed as
the biomechanical limb alignment (centre hip-knee-ankle: HKA-axis)
achieved post-operatively, the position of the individual components
within 3° of the pre-operatively planned alignment, correct planned
implant size and operative data (e.g. operating time and blood loss). Results. The patient demographics (e.g. age, body mass index), correct
planned implant size and operative data were not significantly different
between the two groups. The proportion of outliers in the coronal
and
Introduction. Total knee arthroplasty (TKA) reliably improves pain and function in patients with knee osteoarthritis (OA), though a substantial percentage of patients remain unsatisfied. Reasons include the presence of complications, persistent pain, and unmet expectations. The aim of this study was to determine whether the sequential addition of accelerometer-based navigation of the distal femoral cut and sensor-assisted soft tissue balancing changed complication rates, radiographic alignment, or patient-reported outcomes (PROs) compared to TKA performed with conventional instrumentation. Methods. This retrospective cohort study included 371 TKAs in 319 patients. All surgeries were performed by a single surgeon in sequential fashion using a measured resection technique with a goal of mechanical alignment. The historical control group, utilizing intramedullary guides for distal femoral resection and surgeon-guided soft tissue balancing, was compared to group 1 (accelerometer-based navigation for distal femoral resection, surgeon-guided balancing) and group 2 (navigated femoral resection, sensor-guided balancing). Primary outcome measures were PROMIS scores including physical function computerized adaptive test (PF CAT), and the Global 10 health assessment (including physical, mental, and pain scores), and Knee Injury Osteoarthritis and Outcome Score (KOOS), measured preoperatively and at 6 weeks and 12 months postoperatively. Radiographic measurements included component position and overall mechanical alignment of the limb and were made at 6 weeks by a single examiner from hip to ankle standing films. Charts were reviewed for pre- and postoperative ROM at 6 weeks, polyethylene insert morphology, and postoperative hematocrit change. Complications were recorded, including manipulation under anesthesia and reoperation. Our study was powered to detect a difference of 1 standard deviation in PF CAT score with 100 patients. Statistical analysis was performed by a statistician including t-tests, multivariate regression, and time series plot analyses. Results. There were 194 patients in the control group, 103 in group 1, and 74 in group 2. There was no difference in baseline patient demographics. Patients in group 2 had higher baseline mental health subscores than control and group 1 patients (53.2 vs 50.2 vs 50.2, p=0.04). There were no differences in 6-week and one-year postop PF CAT, physical or mental subscores, pain scores, or KOOS scores (all p>0.05). There were 8 total complications in the control group (4.1%), 4 in group 1 (3.8%), and 1 in group 2 (1.4%) (p>0.4). The postoperative mechanical axis of the limb was within 3 degrees of neutral in 71.6% of control patients, 74.8% in group 1, and 85.1% in group 2 (p=0.1). There was no difference in femoral component coronal alignment between groups (p=0.91), though controls had a small but significantly higher degree of flexion in the
Introduction. Robotic technology has been applied to unicompartmental knee arthroplasty (UKA) in order to improve surgical precision in prosthetic component placement, restore knee anatomic surfaces, and provide a more physiologic ligament tensioning throughout the knee range of motion. Recent literature has demonstrated the reliability of robotic assisted UKA over manual UKA in component placement and executing a soft-tissue tensioning plan. The purpose of this multicenter study was to determine the correlation between 3D component positioning and soft-tissue tensioning with short-term clinical results following robotic assisted medial UKA. Methods. Between 2013 and 2016, 349 patients (381 knees) underwent robotic assisted fixed bearing metal backed medial UKAs at two centres. Follow-up was performed at 12 months minimum. Pre- and post-operatively, patients were administered Knee Injury and Osteoarthritis Score (KOOS), Forgotten Joint Score 12 (FJS), and Short-Form summary scale (SF-12) surveys. Clinical results for every score were stratified as ‘excellent’, ‘mild’ and ‘insufficient’. Post-operative complications were recorded. Failure mechanisms, reoperations and post-operative knee pain were also assessed. Intra-operative robotic data relative to femoral and tibial component placement in the coronal, sagittal and horizontal plane, as well as femoro-tibial gaps at different knee flexion angles were also collected. Results. A total of 338 robotic assisted medial UKAs (309 patients) were assessed at an average follow-up of 33.5 months post-operatively (89% follow-up rate). Three implants were revised, resulting in a survivorship of 99.0% (C.I. 97.0%–99.7%), one for prosthetic joint infection and two for tibial aseptic loosening. All clinical post-operative scores were significantly improved from the pre-operative scores. The following statistically significant correlations were found between intra-operative robotic data and outcomes considered individually: femoral component coronal alignment influenced KOOS Symptoms, Pain and Quality of Life (p<0.05), sagittal alignment influenced KOOS Symptoms and Pain (p<0.05), and femoro-tibial gaps at 20°–30° knee flexion influenced KOOS Pain and Function in Activities of Daily Living (p<0.05). Both, tibial sagittal alignment and femoro-tibial gaps at 80°–90° knee flexion were found to correlate with SF-12 Physical Status and presence of post-operative pain (p<0.01). ‘Excellent’ clinical outcomes were reported by those patients who, on average, had the femur placed in neutral alignment in the coronal and horizontal planes (0.2°±1.5 and 0.6°±1.4 respectively) as well as avoided excessive flexion in the
This prospective study used magnetic resonance imaging to record
This study aimed to evaluate if total knee arthroplasty (TKA) femoral components aligned in either mechanical alignment (MA) or kinematic alignment (KA) are more biomimetic concerning trochlear sulcus orientation and restoration of trochlear height. Bone surfaces from 1,012 CT scans of non-arthritic femora were segmented using a modelling and analytics system. TKA femoral components (Triathlon; Stryker) were virtually implanted in both MA and KA. Trochlear sulcus orientation was assessed by measuring the distal trochlear sulcus angle (DTSA) in native femora and in KA and MA prosthetic femoral components. Trochlear anatomy restoration was evaluated by measuring the differences in medial, lateral, and sulcus trochlear height between native femora and KA and MA prosthetic femoral components.Aims
Methods
We performed a prospective, randomised trial of 44 patients to compare the functional outcomes of a posterior-cruciate-ligament-retaining and posterior-cruciate-ligament-substituting total knee arthroplasty, and to gain a better understanding of the in vivo kinematic behaviour of both devices. At follow-up at five years, no statistically significant differences were found in the clinical outcome measurements for either design. The prevalence of radiolucent lines and the survivorship were the same. In a subgroup of 15 knees, additional image-intensifier analysis in the horizontal and
The goal was to evaluate tibiofemoral knee joint kinematics during stair descent, by simulating the full stair descent motion in vitro. The knee joint kinematics were evaluated for two types of knee implants: bi-cruciate retaining and bi-cruciate stabilized. It was hypothesized that the bi-cruciate retaining implant better approximates native kinematics. The in vitro study included 20 specimens which were tested during a full stair descent with physiological muscle forces in a dynamic knee rig. Laxity envelopes were measured by applying external loading conditions in varus/valgus and internal/external direction.Aims
Methods
We performed a CT-based computer simulation study
to determine how the relationship between any inbuilt posterior
slope in the proximal tibial osteotomy and cutting jig rotational
orientation errors affect tibial component alignment in total knee
replacement. Four different posterior slopes (3°, 5°, 7° and 10°),
each with a rotational error of 5°, 10°, 15°, 20°, 25° or 30°, were
simulated. Tibial cutting block malalignment of 20° of external
rotation can produce varus malalignment of 2.4° and 3.5° with a
7° and a 10° sloped cutting jig, respectively. Care must be taken in
orientating the cutting jig in the