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Bone & Joint Open
Vol. 5, Issue 8 | Pages 681 - 687
19 Aug 2024
van de Graaf VA Shen TS Wood JA Chen DB MacDessi SJ

Aims. Sagittal plane imbalance (SPI), or asymmetry between extension and flexion gaps, is an important issue in total knee arthroplasty (TKA). The purpose of this study was to compare SPI between kinematic alignment (KA), mechanical alignment (MA), and functional alignment (FA) strategies. Methods. In 137 robotic-assisted TKAs, extension and flexion stressed gap laxities and bone resections were measured. The primary outcome was the proportion and magnitude of medial and lateral SPI (gap differential > 2.0 mm) for KA, MA, and FA. Secondary outcomes were the proportion of knees with severe (> 4.0 mm) SPI, and resection thicknesses for each technique, with KA as reference. Results. FA showed significantly lower rates of medial and lateral SPI (2.9% and 2.2%) compared to KA (45.3%; p < 0.001, and 25.5%; p < 0.001) and compared to MA (52.6%; p < 0.001 and 29.9%; p < 0.001). There was no difference in medial and lateral SPI between KA and MA (p = 0.228 and p = 0.417, respectively). FA showed significantly lower rates of severe medial and lateral SPI (0 and 0%) compared to KA (8.0%; p < 0.001 and 7.3%; p = 0.001) and compared to MA (10.2%; p < 0.001 and 4.4%; p = 0.013). There was no difference in severe medial and lateral SPI between KA and MA (p = 0.527 and p = 0.307, respectively). MA resulted in thinner resections than KA in medial extension (mean difference (MD) 1.4 mm, SD 1.9; p < 0.001), medial flexion (MD 1.5 mm, SD 1.8; p < 0.001), and lateral extension (MD 1.1 mm, SD 1.9; p < 0.001). FA resulted in thinner resections than KA in medial extension (MD 1.6 mm, SD 1.4; p < 0.001) and lateral extension (MD 2.0 mm, SD 1.6; p < 0.001), but in thicker medial flexion resections (MD 0.8 mm, SD 1.4; p < 0.001). Conclusion. Mechanical and kinematic alignment (measured resection techniques) result in high rates of SPI. Pre-resection angular and translational adjustments with functional alignment, with typically smaller distal than posterior femoral resection, address this issue. Cite this article: Bone Jt Open 2024;5(8):681–687


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 23 - 23
1 Oct 2019
Meding JB Meding LK Meneghini RM Malinzak RA
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Introduction. Maintaining posterior stability in total knee arthroplasty (TKA) may be achieved by using a posterior stabilized TKA, retaining and balancing the posterior cruciate ligament (PCL) using a traditional cruciate-retaining design (CR), or by increasing the sagittal plane conformity of the tibial insert. In the latter case, stability is achieved by the addition of an anterior buildup on the tibial polyethylene creating the so-called “anterior stabilized” (AS) design. We hypothesized that using an AS tibial insert would provide similar function and survivorship as compared to using a more traditional CR bearing when the PCL is either recessed or balanced. Methods. Between 2004 and 2016, 1,731 modular CR TKAs were implanted in 1,509 patients using the same CR TKA design. The diagnosis was osteoarthritis in 98%. 58% of patients were female. Average age of 64.9 years. Within this group, 868 TKAs (50.1%) had a standard CR tibial bearing (3-degree posterior slope and no posterior lip) implanted (CR-S). 480 TKAs (27.8%) had a lipped CR modular tibial bearing (2.5 mm elevated posterior lip) implanted (CR-L). Starting in 2013, 383 TKAs (22.1%) were implanted with an AS modular tibial bearing (9–11 mm anterior lip and a 5 mm posterior lip). If the PCL was considered non-functional or absent, an AS bearing was placed. If the PCL was considered functional, a standard bearing or lipped bearing was used. Clinical and radiographic analysis was performed according to the Knee Society (KS) grading system. The most recent clinical and radiographic evaluation was used for post-operative analysis. The average follow-up in the entire cohort of TKAs was 5.5 years (range 2 to 14.3 years). Kaplan-Meier analysis was used to determine prosthesis survivorship with failure defined as aseptic loosening of the prosthesis (with or without revision) or tibial insert exchange. Results. At final follow-up, there were no significant differences in knee flexion, pain, function, or stair scores. Walking scores were significantly lower in the AS group. Posterior instability was higher in the CR-S group, whereas the manipulation rate was highest in the CR-L group (1.7% versus 1.3% and 0% in the CR-S and AS groups, respectively). Kaplan-Meier survivorship at five years, excluding infection, demonstrated no significant difference between the three groups (CR-S, CR-L, and AS tibial insert groups, 99% 100% and 99% respectively). Conclusion. When the PCL is considered non-functional at operation, the AS insert provided similar final flexion, function, stair score, and five-year survivorship when compared to using the standard and lipped CR tibial insert when the PCL was balanced. Using an ultra-congruent AS dished tibial component appears to be a reasonable option when the PCL is completely released or found deficient at operation. For figures, tables, or references, please contact authors directly


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 7 | Pages 907 - 913
1 Jul 2011
Ward TR Burns AW Gillespie MJ Scarvell JM Smith PN

Bicruciate-stabilised total knee replacement (TKR) aims to restore normal kinematics by replicating the function of both cruciate ligaments. We performed a prospective, randomised controlled trial in which bicruciate- and posterior-stabilised TKRs were implanted in 13 and 15 osteo-arthritic knees, respectively. The mean age of the bicruciate-stabilised group was 63.9 years (sd 10.00) and that of the posterior-stabilised group 63.2 years (sd 6.7). A control group comprised 14 normal subjects with a mean age of 67.9 years (sd 7.9). The patellar tendon angle (PTA) was measured one week pre-operatively and at seven weeks post-operatively during knee extension, flexion and step-up exercises.

At near full extension during step-up, the bicruciate-stabilised TKR produced a higher mean PTA than the posterior-stabilised TKR, indicating that the bicruciate design at least partially restored the kinematic role of the anterior cruciate ligament. The bicruciate-stabilised TKR largely restored the pre-operative kinematics, whereas the posterior-stabilised TKR resulted in a consistently lower PTA at all activities. The PTA in the pre-operative knees was higher than in the control group during the step-up and at near full knee extension. Overall, both groups generated a more normal PTA than that seen in previous studies in high knee flexion. This suggested that both designs of TKR were more effective at replicating the kinematic role of the posterior cruciate ligament than those used in previous studies.


Bone & Joint Research
Vol. 8, Issue 3 | Pages 126 - 135
1 Mar 2019
Sekiguchi K Nakamura S Kuriyama S Nishitani K Ito H Tanaka Y Watanabe M Matsuda S

Objectives. Unicompartmental knee arthroplasty (UKA) is one surgical option for treating symptomatic medial osteoarthritis. Clinical studies have shown the functional benefits of UKA; however, the optimal alignment of the tibial component is still debated. The purpose of this study was to evaluate the effects of tibial coronal and sagittal plane alignment in UKA on knee kinematics and cruciate ligament tension, using a musculoskeletal computer simulation. Methods. The tibial component was first aligned perpendicular to the mechanical axis of the tibia, with a 7° posterior slope (basic model). Subsequently, coronal and sagittal plane alignments were changed in a simulation programme. Kinematics and cruciate ligament tensions were simulated during weight-bearing deep knee bend and gait motions. Translation was defined as the distance between the most medial and the most lateral femoral positions throughout the cycle. Results. The femur was positioned more medially relative to the tibia, with increasing varus alignment of the tibial component. Medial/lateral (ML) translation was smallest in the 2° varus model. A greater posterior slope posteriorized the medial condyle and increased anterior cruciate ligament (ACL) tension. ML translation was increased in the > 7° posterior slope model and the 0° model. Conclusion. The current study suggests that the preferred tibial component alignment is between neutral and 2° varus in the coronal plane, and between 3° and 7° posterior slope in the sagittal plane. Varus > 4° or valgus alignment and excessive posterior slope caused excessive ML translation, which could be related to feelings of instability and could potentially have negative effects on clinical outcomes and implant durability. Cite this article: K. Sekiguchi, S. Nakamura, S. Kuriyama, K. Nishitani, H. Ito, Y. Tanaka, M. Watanabe, S. Matsuda. Bone Joint Res 2019;8:126–135. DOI: 10.1302/2046-3758.83.BJR-2018-0208.R2


The Bone & Joint Journal
Vol. 103-B, Issue 6 Supple A | Pages 150 - 157
1 Jun 2021
Anderson LA Christie M Blackburn BE Mahan C Earl C Pelt CE Peters CL Gililland J

Aims. Porous metaphyseal cones can be used for fixation in revision total knee arthroplasty (rTKA) and complex TKAs. This metaphyseal fixation has led to some surgeons using shorter cemented stems instead of diaphyseal engaging cementless stems with a potential benefit of ease of obtaining proper alignment without being beholden to the diaphysis. The purpose of this study was to evaluate short term clinical and radiographic outcomes of a series of TKA cases performed using 3D-printed metaphyseal cones. Methods. A retrospective review of 86 rTKAs and nine complex primary TKAs, with an average age of 63.2 years (SD 8.2) and BMI of 34.0 kg/m. 2. (SD 8.7), in which metaphyseal cones were used for both femoral and tibial fixation were compared for their knee alignment based on the type of stem used. Overall, 22 knees had cementless stems on both sides, 52 had cemented stems on both sides, and 15 had mixed stems. Postoperative long-standing radiographs were evaluated for coronal and sagittal plane alignment. Adjusted logistic regression models were run to assess malalignment hip-knee-ankle (HKA) alignment beyond ± 3° and sagittal alignment of the tibial and femoral components ± 3° by stem type. Results. No patients had a revision of a cone due to aseptic loosening; however, two had revision surgery due to infection. In all, 26 (27%) patients had HKA malalignment; nine (9.5%) patients had sagittal plane malalignment, five (5.6%) of the tibia, and four (10.8%) of the femur. After adjusting for age, sex, and BMI, there was a significantly increased risk for malalignment when a cone was used and both the femur and tibia had cementless compared to cemented stems (odds ratio 3.19, 95% confidence interval 1.01 to 10.05). Conclusion. Porous 3D-printed cones provide excellent metaphyseal fixation. However, these central cones make the use of offset couplers difficult and may generate malalignment with cementless stems. We found 3.19-times higher odds of malalignment in our TKAs performed with metaphyseal cones and both femoral and tibial cementless stems. Cite this article: Bone Joint J 2021;103-B(6 Supple A):150–157


Bone & Joint Open
Vol. 4, Issue 6 | Pages 432 - 441
5 Jun 2023
Kahlenberg CA Berube EE Xiang W Manzi JE Jahandar H Chalmers BP Cross MB Mayman DJ Wright TM Westrich GH Imhauser CW Sculco PK

Aims. Mid-level constraint designs for total knee arthroplasty (TKA) are intended to reduce coronal plane laxity. Our aims were to compare kinematics and ligament forces of the Zimmer Biomet Persona posterior-stabilized (PS) and mid-level designs in the coronal, sagittal, and axial planes under loads simulating clinical exams of the knee in a cadaver model. Methods. We performed TKA on eight cadaveric knees and loaded them using a robotic manipulator. We tested both PS and mid-level designs under loads simulating clinical exams via applied varus and valgus moments, internal-external (IE) rotation moments, and anteroposterior forces at 0°, 30°, and 90° of flexion. We measured the resulting tibiofemoral angulations and translations. We also quantified the forces carried by the medial and lateral collateral ligaments (MCL/LCL) via serial sectioning of these structures and use of the principle of superposition. Results. Mid-level inserts reduced varus angulations compared to PS inserts by a median of 0.4°, 0.9°, and 1.5° at 0°, 30°, and 90° of flexion, respectively, and reduced valgus angulations by a median of 0.3°, 1.0°, and 1.2° (p ≤ 0.027 for all comparisons). Mid-level inserts reduced net IE rotations by a median of 5.6°, 14.7°, and 17.5° at 0°, 30°, and 90°, respectively (p = 0.012). Mid-level inserts reduced anterior tibial translation only at 90° of flexion by a median of 3.0 millimetres (p = 0.036). With an applied varus moment, the mid-level insert decreased LCL force compared to the PS insert at all three flexion angles that were tested (p ≤ 0.036). In contrast, with a valgus moment the mid-level insert did not reduce MCL force. With an applied internal rotation moment, the mid-level insert decreased LCL force at 30° and 90° by a median of 25.7 N and 31.7 N, respectively (p = 0.017 and p = 0.012). With an external rotation moment, the mid-level insert decreased MCL force at 30° and 90° by a median of 45.7 N and 20.0 N, respectively (p ≤ 0.017 for all comparisons). With an applied anterior load, MCL and LCL forces showed no differences between the two inserts at 30° and 90° of flexion. Conclusion. The mid-level insert used in this study decreased coronal and axial plane laxities compared to the PS insert, but its stabilizing benefit in the sagittal plane was limited. Both mid-level and PS inserts depended on the MCL to resist anterior loads during a simulated clinical exam of anterior laxity. Cite this article: Bone Jt Open 2023;4(6):432–441


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_9 | Pages 55 - 55
1 Oct 2020
Mahan C Blackburn B Anderson LA Peters CL Pelt CE Gililland JM
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Introduction. Porous metaphyseal cones are increasingly used for fixation in revision total knee arthroplasty (RTKA). Both cemented shorter length stems and longer diaphyseal engaging stems are currently utilized with metaphyseal cones with no clear evidence of superiority. The purpose of this study was to evaluate our experience with 3D printed titanium metaphyseal cones with both short cemented and longer cementless stems from a clinical and radiographic perspective. Methods. In total 136 3D printed titanium metaphyseal cones were implanted. The mean patient age was 63 and 48% were female. The mean BMI was 33 and the mean ASA class was 2.5. There were 42 femoral cones in which 28 cemented and 14 cementless stems were utilized. There were 94 tibial cones in which 67 cemented and 27 cementless stems were utilized. The choice for stem fixation was surgeon dependent and in general cones were utilized for AORI type 2 and 3 bone defects on the femur and tibia. The most common fixation scenario was short cemented stems on both the femur and tibia followed by cemented stem fixation on the tibia and cementless fixation on the femur. Clinical data such as revision, complication, and PRO was collected at last follow-up (minimum follow-up 1 year). Radiographic analysis included cone bony ingrowth and coronal and sagittal alignment on long-standing radiographs. Descriptive statistics were used to compare demographics between patients who had malalignment (HKA beyond +/− 3 degrees and flexion/extension beyond +/− 3 degrees). Adjusted logistic regression models were run to assess malalignment risk by stem type. Results. Patient reported outcomes demonstrated modest improvements with Pre-op KOOS improving from 44 pre-op to 59 post -op and PF-CAT improving from 33 to 37 post-op. PROMIS pain scores decreased significantly from 54 to 44 post-op. 36% of patients had malalignment in either the coronal or sagittal plane. Patients with malalignment were more likely to be female (66.7% vs 40.4%, p-value=0.02). After adjusting for age, sex and BMI, there was a significantly increased risk for coronal plane malalignment when both the femur and tibia had cementless compared to cemented stems (odds ratio=5.54, 95%CI=1.15, 26.80). There was no significantly increased risk when comparing patients with mixed stems to patients with cemented stems. Sagittal plane malalignment was more common with short cemented stems although both coronal plane and sagittal plane malalignment with either stem type was not associated with inferior clinical outcome. Overall cone survivorship was excellent with only two cones removed for infection. Conclusion. Metaphyseal titanium cones provide reliable fixation in revision TKA. However, PROs in this complex patient population show only modest improvement consistent with other variables such as co-morbidities and poor baseline physical function. Small cone inner diameter may adversely influence cementless stem position leading to coronal plane malalignment. Short cemented stems are subject to greater sagittal plane malalignment with no apparent influence on clinical outcome


The Bone & Joint Journal
Vol. 96-B, Issue 8 | Pages 1052 - 1061
1 Aug 2014
Thienpont E Schwab PE Fennema P

We conducted a meta-analysis, including randomised controlled trials (RCTs) and cohort studies, to examine the effect of patient-specific instruments (PSI) on radiological outcomes after total knee replacement (TKR) including: mechanical axis alignment and malalignment of the femoral and tibial components in the coronal, sagittal and axial planes, at a threshold of > 3º from neutral. Relative risks (RR) for malalignment were determined for all studies and for RCTs and cohort studies separately. Of 325 studies initially identified, 16 met the eligibility criteria, including eight RCTs and eight cohort studies. There was no significant difference in the likelihood of mechanical axis malalignment with PSI versus conventional TKR across all studies (RR = 0.84, p = 0.304), in the RCTs (RR = 1.14, p = 0.445) or in the cohort studies (RR = 0.70, p = 0.289). The results for the alignment of the tibial component were significantly worse using PSI TKR than conventional TKR in the coronal and sagittal planes (RR = 1.75, p = 0.028; and RR = 1.34, p = 0.019, respectively, on pooled analysis). PSI TKR showed a significant advantage over conventional TKR for alignment of the femoral component in the coronal plane (RR = 0.65, p = 0.028 on pooled analysis), but not in the sagittal plane (RR = 1.12, p = 0.437). Axial alignment of the tibial (p = 0.460) and femoral components (p = 0.127) was not significantly different. We conclude that PSI does not improve the accuracy of alignment of the components in TKR compared with conventional instrumentation. Cite this article: Bone Joint J 2014; 96-B:1052–61


Bone & Joint Open
Vol. 3, Issue 7 | Pages 589 - 595
1 Jul 2022
Joo PY Chen AF Richards J Law TY Taylor K Marchand K Clark G Collopy D Marchand RC Roche M Mont MA Malkani AL

Aims. The aim of this study was to report patient and clinical outcomes following robotic-assisted total knee arthroplasty (RA-TKA) at multiple institutions with a minimum two-year follow-up. Methods. This was a multicentre registry study from October 2016 to June 2021 that included 861 primary RA-TKA patients who completed at least one pre- and postoperative patient-reported outcome measure (PROM) questionnaire, including Forgotten Joint Score (FJS), Knee Injury and Osteoarthritis Outcomes Score for Joint Replacement (KOOS JR), and pain out of 100 points. The mean age was 67 years (35 to 86), 452 were male (53%), mean BMI was 31.5 kg/m. 2. (19 to 58), and 553 (64%) cemented and 308 (36%) cementless implants. Results. There were significant improvements in PROMs over time between preoperative, one- to two-year, and > two-year follow-up, with a mean FJS of 17.5 (SD 18.2), 70.2 (SD 27.8), and 76.7 (SD 25.8; p < 0.001); mean KOOS JR of 51.6 (SD 11.5), 85.1 (SD 13.8), and 87.9 (SD 13.0; p < 0.001); and mean pain scores of 65.7 (SD 20.4), 13.0 (SD 19.1), and 11.3 (SD 19.9; p < 0.001), respectively. There were eight superficial infections (0.9%) and four revisions (0.5%). Conclusion. RA-TKA demonstrated consistent clinical results across multiple institutions with excellent PROMs that continued to improve over time. With the ability to achieve target alignment in the coronal, axial, and sagittal planes and provide intraoperative real-time data to obtain balanced gaps, RA-TKA demonstrated excellent clinical outcomes and PROMs in this patient population. Cite this article: Bone Jt Open 2022;3(7):589–595


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 10 | Pages 1392 - 1396
1 Oct 2010
Wang J Chen W Lin P Hsu C Wang C

Intra-articular resection of bone with soft-tissue balancing and total knee replacement (TKR) has been described for the treatment of patients with severe osteoarthritis of the knee associated with an ipsilateral malunited femoral fracture. However, the extent to which deformity in the sagittal plane can be corrected has not been addressed. We treated 12 patients with severe arthritis of the knee and an extra-articular malunion of the femur by TKR with intra-articular resection of bone and soft-tissue balancing. The femora had a mean varus deformity of 16° (8° to 23°) in the coronal plane. There were seven recurvatum deformities with a mean angulation of 11° (6° to 15°) and five antecurvatum deformities with a mean angulation of 12° (6° to 15°). The mean follow-up was 93 months (30 to 155). The median Knee Society knee and function scores improved from 18.7 (0 to 49) and 24.5 (10 to 50) points pre-operatively to 93 (83 to 100) and 90 (70 to 100) points at the time of the last follow-up, respectively. The mean mechanical axis of the knee improved from 22.6° of varus (15° to 27° pre-operatively to 1.5° of varus (3° of varus to 2° of valgus) at the last follow-up. The recurvatum deformities improved from a mean of 11° (6° to 15°) pre-operatively to 3° (0° to 6°) at the last follow-up. The antecurvatum deformities in the sagittal plane improved from a mean of 12° (6° to 16°) pre-operatively to 4.4° (0° to 8°) at the last follow-up. Apart from varus deformities, TKR with intra-articular bone resection effectively corrected the extra-articular deformity of the femur in the presence of antecurvatum of up to 16° and recurvatum of up to 15°


The Bone & Joint Journal
Vol. 96-B, Issue 12 | Pages 1623 - 1630
1 Dec 2014
Monk AP Choji K O’Connor JJ Goodfellow† JW Murray DW

We scanned 25 left knees in healthy human subjects using MRI. Multiplanar reconstruction software was used to take measurements of the inferior and posterior facets of the femoral condyles and the trochlea. A ‘basic circle’ can be defined which, in the sagittal plane, fits the posterior and inferior facets of the lateral condyle, the posterior facet of the medial condyle and the floor of the groove of the trochlea. It also approximately fits both condyles in the coronal plane (inferior facets) and the axial plane (posterior facets). The circle fitting the inferior facet of the medial condyle in the sagittal plane was consistently 35% larger than the other circles and was termed the ‘medial inferior circle’. There were strong correlations between the radii of the circles, the relative positions of the centres of the condyles, the width of the condyles, the total knee width and skeletal measurements including height. There was poor correlation between the radii of the circles and the position of the trochlea relative to the condyles. In summary, the condyles are approximately spherical except for the inferior facet medially, which has a larger radius in the sagittal plane. The size and position of the condyles are consistent and change with the size of the person. However, the position of the trochlea is variable even though its radius is similar to that of the condyles. This information has implications for understanding anterior knee pain and for the design of knee replacements. Cite this article: Bone Joint J 2014;96-B:1623–30


The Bone & Joint Journal
Vol. 95-B, Issue 11_Supple_A | Pages 153 - 158
1 Nov 2013
Victor J Premanathan A

We have investigated the benefits of patient specific instrument guides, applied to osteotomies around the knee. Single, dual and triple planar osteotomies were performed on tibias or femurs in 14 subjects. In all patients, a detailed pre-operative plan was prepared based upon full leg standing radiographic and CT scan information. The planned level of the osteotomy and open wedge resection was relayed to the surgery by virtue of a patient specific guide developed from the images. The mean deviation between the planned wedge angle and the executed wedge angle was 0° (-1 to 1, . sd. 0.71) in the coronal plane and 0.3° (-0.9 to 3, . sd. 1.14) in the sagittal plane. The mean deviation between the planned hip, knee, ankle angle (HKA) on full leg standing radiograph and the post-operative HKA was 0.3° (-1 to 2, . sd. 0.75). It is concluded that this is a feasible and valuable concept from the standpoint of pre-operative software based planning, surgical application and geometrical accuracy of outcome. . Cite this article: Bone Joint J 2013;95-B, Supple A:153–8


The Bone & Joint Journal
Vol. 98-B, Issue 6 | Pages 786 - 792
1 Jun 2016
Schotanus MGM Sollie R van Haaren EH Hendrickx RPM Jansen EJP Kort NP

Aims. This prospective randomised controlled trial was designed to evaluate the outcome of both the MRI- and CT-based patient-specific matched guides (PSG) from the same manufacturer. Patients and Methods. A total of 137 knees in 137 patients (50 men, 87 women) were included, 67 in the MRI- and 70 in the CT-based PSG group. Their mean age was 68.4 years (47.0 to 88.9). Outcome was expressed as the biomechanical limb alignment (centre hip-knee-ankle: HKA-axis) achieved post-operatively, the position of the individual components within 3° of the pre-operatively planned alignment, correct planned implant size and operative data (e.g. operating time and blood loss). Results. The patient demographics (e.g. age, body mass index), correct planned implant size and operative data were not significantly different between the two groups. The proportion of outliers in the coronal and sagittal plane ranged from 0% to 21% in both groups. Only the number of outliers for the posterior slope of the tibial component showed a significant difference (p = 0.004) with more outliers in the CT group (n = 9, 13%) than in the MRI group (0%). . Conclusion. The post-operative HKA-axis was comparable in the MRI- and CT-based PSGs, but there were significantly more outliers for the posterior slope in the CT-based PSGs. Take home message: Alignment with MRI-based PSG is at least as good as, if not better, than that of the CT-based PSG, and is the preferred imaging modality when performing TKA with use of PSG. Cite this article: Bone Joint J 2016;98-B:786–92


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 24 - 24
1 Oct 2019
Livermore AT Erickson J Hickerson M Peters CL
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Introduction. Total knee arthroplasty (TKA) reliably improves pain and function in patients with knee osteoarthritis (OA), though a substantial percentage of patients remain unsatisfied. Reasons include the presence of complications, persistent pain, and unmet expectations. The aim of this study was to determine whether the sequential addition of accelerometer-based navigation of the distal femoral cut and sensor-assisted soft tissue balancing changed complication rates, radiographic alignment, or patient-reported outcomes (PROs) compared to TKA performed with conventional instrumentation. Methods. This retrospective cohort study included 371 TKAs in 319 patients. All surgeries were performed by a single surgeon in sequential fashion using a measured resection technique with a goal of mechanical alignment. The historical control group, utilizing intramedullary guides for distal femoral resection and surgeon-guided soft tissue balancing, was compared to group 1 (accelerometer-based navigation for distal femoral resection, surgeon-guided balancing) and group 2 (navigated femoral resection, sensor-guided balancing). Primary outcome measures were PROMIS scores including physical function computerized adaptive test (PF CAT), and the Global 10 health assessment (including physical, mental, and pain scores), and Knee Injury Osteoarthritis and Outcome Score (KOOS), measured preoperatively and at 6 weeks and 12 months postoperatively. Radiographic measurements included component position and overall mechanical alignment of the limb and were made at 6 weeks by a single examiner from hip to ankle standing films. Charts were reviewed for pre- and postoperative ROM at 6 weeks, polyethylene insert morphology, and postoperative hematocrit change. Complications were recorded, including manipulation under anesthesia and reoperation. Our study was powered to detect a difference of 1 standard deviation in PF CAT score with 100 patients. Statistical analysis was performed by a statistician including t-tests, multivariate regression, and time series plot analyses. Results. There were 194 patients in the control group, 103 in group 1, and 74 in group 2. There was no difference in baseline patient demographics. Patients in group 2 had higher baseline mental health subscores than control and group 1 patients (53.2 vs 50.2 vs 50.2, p=0.04). There were no differences in 6-week and one-year postop PF CAT, physical or mental subscores, pain scores, or KOOS scores (all p>0.05). There were 8 total complications in the control group (4.1%), 4 in group 1 (3.8%), and 1 in group 2 (1.4%) (p>0.4). The postoperative mechanical axis of the limb was within 3 degrees of neutral in 71.6% of control patients, 74.8% in group 1, and 85.1% in group 2 (p=0.1). There was no difference in femoral component coronal alignment between groups (p=0.91), though controls had a small but significantly higher degree of flexion in the sagittal plane (6.5 degrees) than groups 1 and 2 (5.4 degrees in both, p=0.003). There was no difference in postoperative ROM or blood loss. Conclusions. The sequential addition of imageless navigation of the distal femoral cut and sensor-guided ligament balancing did not confer any benefit to short term PROs, radiographic outcomes, or complication rates over conventional techniques. While overall mechanical alignment of the limb was improved in groups 1 and 2 compared to controls, this did not reach statistical significance. The additive costs of navigation and soft-tissue balancing technologies may not be justified. For figures, tables, or references, please contact authors directly


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 3 - 3
1 Oct 2018
Catani F Zambianchi F Marcovigi A Franceschi G Nardacchione R
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Introduction. Robotic technology has been applied to unicompartmental knee arthroplasty (UKA) in order to improve surgical precision in prosthetic component placement, restore knee anatomic surfaces, and provide a more physiologic ligament tensioning throughout the knee range of motion. Recent literature has demonstrated the reliability of robotic assisted UKA over manual UKA in component placement and executing a soft-tissue tensioning plan. The purpose of this multicenter study was to determine the correlation between 3D component positioning and soft-tissue tensioning with short-term clinical results following robotic assisted medial UKA. Methods. Between 2013 and 2016, 349 patients (381 knees) underwent robotic assisted fixed bearing metal backed medial UKAs at two centres. Follow-up was performed at 12 months minimum. Pre- and post-operatively, patients were administered Knee Injury and Osteoarthritis Score (KOOS), Forgotten Joint Score 12 (FJS), and Short-Form summary scale (SF-12) surveys. Clinical results for every score were stratified as ‘excellent’, ‘mild’ and ‘insufficient’. Post-operative complications were recorded. Failure mechanisms, reoperations and post-operative knee pain were also assessed. Intra-operative robotic data relative to femoral and tibial component placement in the coronal, sagittal and horizontal plane, as well as femoro-tibial gaps at different knee flexion angles were also collected. Results. A total of 338 robotic assisted medial UKAs (309 patients) were assessed at an average follow-up of 33.5 months post-operatively (89% follow-up rate). Three implants were revised, resulting in a survivorship of 99.0% (C.I. 97.0%–99.7%), one for prosthetic joint infection and two for tibial aseptic loosening. All clinical post-operative scores were significantly improved from the pre-operative scores. The following statistically significant correlations were found between intra-operative robotic data and outcomes considered individually: femoral component coronal alignment influenced KOOS Symptoms, Pain and Quality of Life (p<0.05), sagittal alignment influenced KOOS Symptoms and Pain (p<0.05), and femoro-tibial gaps at 20°–30° knee flexion influenced KOOS Pain and Function in Activities of Daily Living (p<0.05). Both, tibial sagittal alignment and femoro-tibial gaps at 80°–90° knee flexion were found to correlate with SF-12 Physical Status and presence of post-operative pain (p<0.01). ‘Excellent’ clinical outcomes were reported by those patients who, on average, had the femur placed in neutral alignment in the coronal and horizontal planes (0.2°±1.5 and 0.6°±1.4 respectively) as well as avoided excessive flexion in the sagittal plane (3.7°±3.2). When considering the tibia, better results were reported by patients with the tibial component placed in slight external rotation (2.2°±1.7), varus coronal alignment (1.5°±1.7) and no more than 5° of posterior slope (5.0°±1.0). Regarding femoro-tibial gaps, ‘excellent’ clinical outcomes were reported by patients who were slightly loose between 20°–30° and 80°–90° of knee flexion. Conclusion. In the present study, survivorship and clinical outcomes of a large cohort of 309 patients with medial robotic assisted UKA were contacted with at a mean 3-years. The overall survivorship was found to be 99%, with tibial component failure as the most common reason for UKA revision. The significant difference between pre- and post-operative clinical scores highlights the efficacy of robotic assisted UKA in restoring knee function and relieving pain. Differences in components’ positioning and soft-tissue tensioning demonstrated significant correlation with post-operative clinical outcomes


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 3 | Pages 324 - 330
1 Mar 2006
Scarvell JM Smith PN Refshauge KM Galloway HR Woods KR

This prospective study used magnetic resonance imaging to record sagittal plane tibiofemoral kinematics before and after anterior cruciate ligament reconstruction using autologous hamstring graft. Twenty patients with anterior cruciate ligament injuries, performed a closed-chain leg-press while relaxed and against a 150 N load. The tibiofemoral contact patterns between 0° to 90° of knee flexion were recorded by magnetic resonance scans. All measurements were performed pre-operatively and repeated at 12 weeks and two years. Following reconstruction there was a mean passive anterior laxity of 2.1 mm (. sd. 2.3), as measured using a KT 1000 arthrometer, and the mean Cincinnati score was 90 (. sd. 11) of 100. Pre-operatively, the medial and lateral contact patterns of the injured knees were located posteriorly on the tibial plateau compared with the healthy contralateral knees (p = 0.014), but were no longer different at 12 weeks (p = 0.117) or two years postoperatively (p = 0.909). However, both reconstructed and healthy contralateral knees showed altered kinematics over time. At two years, the contact pattern showed less posterior translation of the lateral femoral condyle during flexion (p < 0.01)


The Bone & Joint Journal
Vol. 106-B, Issue 8 | Pages 817 - 825
1 Aug 2024
Borukhov I Ismailidis P Esposito CI LiArno S Lyon J McEwen PJ

Aims

This study aimed to evaluate if total knee arthroplasty (TKA) femoral components aligned in either mechanical alignment (MA) or kinematic alignment (KA) are more biomimetic concerning trochlear sulcus orientation and restoration of trochlear height.

Methods

Bone surfaces from 1,012 CT scans of non-arthritic femora were segmented using a modelling and analytics system. TKA femoral components (Triathlon; Stryker) were virtually implanted in both MA and KA. Trochlear sulcus orientation was assessed by measuring the distal trochlear sulcus angle (DTSA) in native femora and in KA and MA prosthetic femoral components. Trochlear anatomy restoration was evaluated by measuring the differences in medial, lateral, and sulcus trochlear height between native femora and KA and MA prosthetic femoral components.


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 5 | Pages 646 - 655
1 May 2005
Victor J Banks S Bellemans J

We performed a prospective, randomised trial of 44 patients to compare the functional outcomes of a posterior-cruciate-ligament-retaining and posterior-cruciate-ligament-substituting total knee arthroplasty, and to gain a better understanding of the in vivo kinematic behaviour of both devices. At follow-up at five years, no statistically significant differences were found in the clinical outcome measurements for either design. The prevalence of radiolucent lines and the survivorship were the same. In a subgroup of 15 knees, additional image-intensifier analysis in the horizontal and sagittal planes was performed during step-up and lunge activity. Our analysis revealed striking differences. Lunge activity showed a mean posterior displacement of both medial and lateral tibiofemoral contact areas (roll-back) which was greater and more consistent in the cruciate-substituting than in the cruciate-retaining group (medial p < 0.0001, lateral p = 0.011). The amount of posterior displacement could predict the maximum flexion which could be achieved (p = 0.018). Forward displacement of the tibiofemoral contact area in flexion during stair activity was seen more in the cruciate-retaining than in the cruciate-substituting group. This was attributed mainly to insufficiency of the posterior cruciate ligament and partially to that of the anterior cruciate ligament. We concluded that, despite similar clinical outcomes, there are significant kinematic differences between cruciate-retaining and cruciate-substituting arthroplasties


Bone & Joint Research
Vol. 12, Issue 4 | Pages 285 - 293
17 Apr 2023
Chevalier A Vermue H Pringels L Herregodts S Duquesne K Victor J Loccufier M

Aims

The goal was to evaluate tibiofemoral knee joint kinematics during stair descent, by simulating the full stair descent motion in vitro. The knee joint kinematics were evaluated for two types of knee implants: bi-cruciate retaining and bi-cruciate stabilized. It was hypothesized that the bi-cruciate retaining implant better approximates native kinematics.

Methods

The in vitro study included 20 specimens which were tested during a full stair descent with physiological muscle forces in a dynamic knee rig. Laxity envelopes were measured by applying external loading conditions in varus/valgus and internal/external direction.


The Bone & Joint Journal
Vol. 95-B, Issue 9 | Pages 1201 - 1203
1 Sep 2013
Tsukeoka T Tsuneizumi Y Lee TH

We performed a CT-based computer simulation study to determine how the relationship between any inbuilt posterior slope in the proximal tibial osteotomy and cutting jig rotational orientation errors affect tibial component alignment in total knee replacement. Four different posterior slopes (3°, 5°, 7° and 10°), each with a rotational error of 5°, 10°, 15°, 20°, 25° or 30°, were simulated. Tibial cutting block malalignment of 20° of external rotation can produce varus malalignment of 2.4° and 3.5° with a 7° and a 10° sloped cutting jig, respectively. Care must be taken in orientating the cutting jig in the sagittal plane when making a posterior sloped proximal tibial osteotomy in total knee replacement. Cite this article: Bone Joint J 2013;95-B:1201–3