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The Bone & Joint Journal
Vol. 96-B, Issue 12 | Pages 1706 - 1712
1 Dec 2014
Bus MPA Boerhout EJ Bramer JAM Dijkstra PDS

Peri-acetabular tumour resections and their subsequent reconstruction are among the most challenging procedures in orthopaedic oncology. Despite the fact that a number of different pelvic endoprostheses have been introduced, rates of complication remain high and long-term results are mostly lacking. . In this retrospective study, we aimed to evaluate the outcome of reconstructing a peri-acetabular defect with a pedestal cup endoprosthesis after a type 2 or type 2/3 internal hemipelvectomy. A total of 19 patients (11M:8F) with a mean age of 48 years (14 to 72) were included, most of whom had been treated for a primary bone tumour (n = 16) between 2003 and 2009. After a mean follow-up of 39 months (28 days to 8.7 years) seven patients had died. After a mean follow-up of 7.9 years (4.3 to 10.5), 12 patients were alive, of whom 11 were disease-free. Complications occurred in 15 patients. Three had recurrent dislocations and three experienced aseptic loosening. There were no mechanical failures. Infection occurred in nine patients, six of whom required removal of the prosthesis. Two patients underwent hindquarter amputation for local recurrence. The implant survival rate at five years was 50% for all reasons, and 61% for non-oncological reasons. The mean Musculoskeletal Tumor Society score at final follow-up was 49% (13 to 87). Based on these poor results, we advise caution if using the pedestal cup for reconstruction of a peri-acetabular tumour resection. Cite this article: Bone Joint J 2014;96-B:1706–12


Bone & Joint Research
Vol. 2, Issue 8 | Pages 140 - 148
1 Aug 2013
Gauthier L Dinh L Beaulé PE

Objectives. To quantify and compare peri-acetabular bone mineral density (BMD) between a monoblock acetabular component using a metal-on-metal (MoM) bearing and a modular titanium shell with a polyethylene (PE) insert. The secondary outcome was to measure patient-reported clinical function. Methods. A total of 50 patients (25 per group) were randomised to MoM or metal-on-polyethlene (MoP). There were 27 women (11 MoM) and 23 men (14 MoM) with a mean age of 61.6 years (47.7 to 73.2). Measurements of peri-prosthetic acetabular and contralateral hip (covariate) BMD were performed at baseline and at one and two years’ follow-up. The Western Ontario and McMaster Universities osteoarthritis index (WOMAC), University of California, Los Angeles (UCLA) activity score, Harris hip score, and RAND-36 were also completed at these intervals. Results. At two years, only zone 1 showed a loss in BMD (-2.5%) in MoM group compared with a gain in the MoP group (+2.2%). Zone 2 showed loss in both groups (-2.2% for MoM; -3.9% for MoP) and zones 3 and 4 a gain in both groups (+0.1% for MoM; +3.3% for MoP). No other between-group differences were detected. When adjusting for BMD of the contralateral hip, no differences in BMD were observed. The only significant differences in functional scores at two years were higher UCLA activity (7.3 (. sd. 1.2) vs 6.1 (. sd. 1.5); p = 0.01) and RAND-36 physical function (82.1 (. sd. 13.0) vs 64.5 (. sd. 26.4); p = 0.02) for MoM bearings versus MoP. One revision was performed in the MoM group, for aseptic acetabular loosening at 11 months. Conclusions. When controlling for systemic BMD, there were no significant differences between MoM and MoP groups in peri-acetabular BMD. However, increasing reports of adverse tissue reactions with large head MoM THR have restricted the use of the monoblock acetabular component to resurfacing only


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 3 | Pages 371 - 376
1 Mar 2008
Falkinstein Y Ahlmann ER Menendez LR

We report our early experience with a new peri-acetabular reconstruction endoprosthesis used for pelvic reconstruction after tumour resection. The outcome of 21 patients who underwent limb salvage following type II pelvic resection and reconstruction using the peri-acetabular reconstruction prosthesis between 2000 and 2006 was retrospectively reviewed. This prosthesis was designed to use the remaining part of the ilium to support a horizontally placed acetabular component secured with internal fixation and bone cement. Into this device a constrained acetabular liner is positioned which is articulates with a conventional femoral component to which a modular extension and modular head are attached. The mean follow-up was 20.5 months (1 to 77). The most common complications were deep infection, superficial wound infections, and dislocation. The mean musculoskeletal tumor society functional outcome score for the survivors was 20.1(11 to 27). We recommend the use of the peri-acetabular reconstruction prosthesis for reconstruction of large defects after type II pelvic resection, as this design has a greater inherent stability over other available prostheses


The Bone & Joint Journal
Vol. 96-B, Issue 9 | Pages 1155 - 1160
1 Sep 2014
Kosuge D Cordier T Solomon LB Howie DW

Peri-acetabular osteotomy is an established surgical treatment for symptomatic acetabular dysplasia in young adults. An anteroposterior radiograph of the pelvis is commonly used to assess the extent of dysplasia as well as to assess post-operative correction. Radiological prognostic factors include the lateral centre-edge angle, acetabular index, extrusion index and the acetabular version. Standing causes a change in the pelvis tilt which can alter certain radiological measurements relative to the supine position. This article discusses the radiological indices used to assess dysplasia and reviews the effects of patient positioning on these indices with a focus on assessment for a peri-acetabular osteotomy. Intra-operatively, fluoroscopy is commonly used and the implications of using fluoroscopy as a modality to assess the various radiological indices along with the effects of using an anteroposterior or posteroanterior fluoroscopic view are examined. Each of these techniques gives rise to a slightly different image of the pelvis as the final image is sensitive to the position of the pelvis and the projection of the x-ray beam. Cite this article: Bone Joint J 2014;96-B:1155–60


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 8 | Pages 1104 - 1110
1 Aug 2011
Ji T Guo W Yang R Tang S Sun X

We set out to determine the impact of surgery on quality of life and function in patients who had undergone surgery for symptomatic peri-acetabular metastases. From a prospective database we retrospectively reviewed 46 consecutive patients who had been treated operatively between June 2003 and June 2009. The mean age of the patients was 56.4 years (20 to 73) and the mean post-operative follow-up was 19.2 months (4 to 70). Functional evaluation and quality-of-life assessments were performed. At the most recent follow-up, 26 patients (56.5%) were alive. Their median survival time was 25.0 months. Ten major postoperative complications had occurred in eight patients (17.4%). The mean post-operative Musculoskeletal Tumor Society score (MSTS 93) was 56.3% (6.7% to 90.0%). Improvement in the Eastern Cooperative Oncology Group (ECOG) performance status was seen in 32 patients (69.6%). On the European Organisation for Research and Treatment of Cancer core quality-of-life questionnaire (QLQ-C30) measure of global health status there was a statistically significant improvement from the patients’ pre-operative status (42.8 (. sd. 13.7)) to that found at the latest follow-up (58.0 (. sd. 12.5)) (p = 0.001). The only statistically significant change in the nine symptom domains of the QLQ-C30 was a reduction in the mean level of pain (from 59.1 to 29.5 (out of 100)) (p < 0.001). Surgery for patients with peri-acetabular metastases reduces pain and improves their quality of life, and has a low rate of surgical complications


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 6 | Pages 732 - 737
1 Jun 2011
Kim K Cho Y Ramteke AA Yoo M

Reconstructive acetabular osteotomy is a well established and effective procedure in the treatment of acetabular dysplasia. However, the dysplasia is frequently accompanied by intra-articular pathology such as labral tears. We intended to determine whether a concomitant hip arthroscopy with peri-acetabular rotational osteotomy could identify and treat intra-articular pathology associated with dysplasia and thereby produce a favourable outcome. We prospectively evaluated 43 consecutive hips treated by combined arthroscopy and acetabular osteotomy. Intra-operative arthroscopic examination revealed labral lesions in 38 hips. At a mean follow-up of 74 months (60 to 97) the mean Harris hip score improved from 72.4 to 94.0 (p < 0.001), as did all the radiological parameters (p < 0.001). Complications included penetration of the joint by the osteotome in one patient, a fracture of the posterior column in another and deep-vein thrombosis in one further patient. This combined surgical treatment gave good results in the medium term. We suggest that arthroscopy of the hip can be performed in conjunction with peri-acetabular osteotomy to provide good results in patients with symptomatic dysplasia of the hip, and the arthroscopic treatment of intra-articular pathology may alter the progression of osteoarthritis


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 68 - 69
1 Jan 2004
Kapoor B Wynn-Jones C
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Introduction: Peri-acetabular rotational osteotomy is recognized as the non-arthroplastic treatment for Developmental Dysplasia of the Hip (DDH). This procedure has increased in popularity during the last decade. It aims to restore the acetabular cover over the femoral head and thus delay secondary osteoarthritic changes in the hip. Materials and methods: We reviewed 16 patients who underwent peri-acetabular rotational surgery at our hospital. The indication for surgery was DDH in all cases. Reinert’s approach was used for surgical exposure. Two patients underwent a valgus femoral osteotomy at the same time. Mean age was 40 years (range 15–49). The mean follow-up was 46.5 months (range 4–108). The results of the surgery were assessed with radiological indices and a patient satisfaction survey. The radiological indices recorded were Wiberg’s angle, acetabular inclination angle, femoral head extrusion index and Tonnis osteoarthritis grading. Results: The intervention failed to benefit two patients who subsequently required a total hip arthroplasty. Both patients had Tonnis grade 3 osteoarthritis. One patient developed a necrotic skin flap requiring skin grafting. The mean pre-operative Wiberg’s angle was 11 degrees (range −7 to 25) which was corrected to 35 degrees (range 17 to 58). Mean pre-operative acetabular index was 25 degrees (range 14 to 40) which was corrected to 11 degrees (range of 2 to 21). Mean pre-operative femoral head extrusion index was 37 degrees (range 18–50) which was reduced to 14 degrees (range 0–32). In all but the two patients in whom the surgery had failed, patients reported reduction in hip pain. Conclusions: Peri-acetabular rotational osteotomy is a challenging but worthwhile procedure for young patients with DDH. The early results from the procedure are encouraging providing patient selection is appropriate. We would like to initiate a debate to identify the ideal patient for this procedure


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XIV | Pages 38 - 38
1 Apr 2012
Jansen J Dijkstra P Taminiau A
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Aim. The saddle prosthesis was originally developed for reconstruction of large acetabular defects in hip revision arthroplasty. Later on the saddle prosthesis was also used for hip reconstruction after resection of peri-acetabular tumours. In case of patient survival a long-term good hip function is required of the saddle prosthesis. The goal of this study is the measurement of long-term clinical results of saddle prosthesis after reconstruction of peri-acetabular tumours. Method. Between 1987 and 2003 a total of 17 patients were treated in the Leiden University Medical Center with saddle prosthesis after resection of peri-acetabular tumours (12 chondrosarcoma, 3 osteosarcoma, 1 malignant fibrous histiocytoma, 1 metastasis). 11 of the 17 patients died, the mean survival was 37 months (range 2-59 months), and 6 patients were still alive (follow-up 12.1 year, range 8.3–16.8 year). The outcome was measured with the SF-36 questionnaire, the Toronto Extrimity Salvage Score (TESS) and the Musculo Skeletal Tumour Society (MSTS) score. In 1 patient the saddle prosthesis was removed already after 3 months because of luxation and infection. Results. In 13 of the 17 patients the use of walking devices was known: 54% required two crutches, 38% one crutch, and 8% no walking aids. The mean hip flexion was 60 degrees (range 40-100 degrees). Local complications were seen in 14 of the 17 patients: 9 wound infections, 7 luxations, and 2 leg length discrepancies requiring additional surgery. In the 5 surviving patients the MSTS score at long-term follow up was 47%, the mean TESS score was 53%, the mean composite SF-36 physical and mental scores were 43.92 and 50.64 respectively. Conclusion. Reconstruction with saddle prosthesis after peri-acetabular tumour surgery has a high risk of complications, and poor long term functional outcome with limited flexion of the hip


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 9 | Pages 1222 - 1227
1 Sep 2008
Jaiswal PK Aston WJS Grimer RJ Abudu A Carter S Blunn G Briggs TWR Cannon S

We treated 98 patients with peri-acetabular tumours by resection and reconstruction with a custom-made pelvic endoprosthesis. The overall survival of the patients was 67% at five years, 54% at ten years and 51% at 30 years. One or more complications occurred in 58.1% of patients (54), of which infection was the most common, affecting 30% (28 patients). The rate of local recurrence was 31% (29 patients) after a mean follow-up of 71 months (11 to 147). Dislocation occurred in 20% of patients (19). Before 1996 the rate was 40.5% (17 patients) but this was reduced to 3.9% (two patients) with the introduction of a larger femoral head. There were six cases of palsy of the femoral nerve with recovery in only two. Revision or excision arthroplasty was performed in 23.7% of patients (22), principally for uncontrolled infection or aseptic loosening. Higher rates of death, infection and revision occurred in men. This method of treatment is still associated with high morbidity. Patients should be carefully selected and informed of this pre-operatively


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 467 - 468
1 Apr 2004
Stamenkov R Howie D Taylor J Findlay D McGee M Kourlis G Callary S Pannach S
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Introduction Peri-acetabular osteolysis is a serious complication of total hip arthroplasty (THA). The aim of this study was to determine, using quantitative computed tomography (CT), the location, volume and rate of progression of peri-acetabular osteolytic lesions, and to determine the validity of this CT technique with intra-operative measurements. Methods High-resolution spiral multislice CT scan (Somatom Volume Zoom, Siemens, Munich, Germany), with metal-artefact suppression protocol, was used to measure the volume of osteolytic lesions around 47 cementless THAs in 36 patients (median age 73 years, duration 14 years, range five to 24 years). In vitro validation was undertaken. CT scans were taken from the top of sacroiliac joint down to two centimetres below the end of the prosthesis. Reconstruction images were analysed by two different observers and progression of osteolysis with time was determined. In some patients, subsequently revised, in-vivo CT measurements were compared to intra-operative measurements. The rate of progression of osteolytic lesions was calculated. The technique was optimised and validated by extensive in-vitro studies, using bovine and human pelves. Results The incidence of lesions located in each site was: the ilium, 65%; around fixation screws, 20%; in the anterior column, nine percent; and in the medial wall, six percent. Some lesions were shown to be relatively quiescent, while others were aggressively osteolytic. Intra and inter-observer error for the CT measurement technique was four percent and 2.8%, respectively. In vitro volumetric measurements of simulated bone defects adjacent to the acetabular component and fixation screw were accurate to within 96% and precise to 98%. In addition, preliminary data obtained intra-operatively indicate the accuracy of CT in identifying the sites of osteolysis. Conclusions CT is thus a valid and reliable technique for investigating the natural history of osteolysis and the factors that may influence its progression. It will also enable assessment of non-surgical treatments of osteolysis. In relation to the conduct of this study, one or more of the authors is in receipt of a research grant from a non-commercial source


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 245 - 246
1 May 2006
Yeung E Rahman A Witt J
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Pelvic and acetabular surgery may be associated with significant blood loss because of the vascularity and anatomy of the pelvis. Concerns continue in relation to blood transfusion because of the potential for disease transmission and because of the increasing cost of providing safe blood products. The purpose of this study was to examine in a retrospective fashion the blood transfusion requirements in a consecutive series of patients undergoing peri-acetabular osteotomy for hip dysplasia. Surgery was performed under general anaesthesia with an epidural in place in the majority of cases. A cell saver was not used and no pre operative autologous blood donation was performed. In seven cases one unit of blood was drawn off immediately prior to the operation in the anaesthetic room and re-infused towards the end of the operation. This practice was discontinued when one of these units clotted and could not be re-infused. A post-operative transfusion policy was adopted where an haemoglobin (Hb) concentration of < 7.5 g/dl was an indication for transfusion. There were 19 females and 2 males. The average age was 26.6 (range 14 – 40). The average duration of surgery was 233mins (range 180 – 285min). Pre-operatively the average Hb concentration was 13.68 g/dl (range 12.3 – 16.2 g/dl). Overall 16 patients did not require any cross-matched transfusion. Two patients received one unit of blood and three received two units. If the transfusion policy had been correctly followed, 4 of these patients would not have received cross-matched blood. The average post-op Hb in those not receiving transfusion was 8.6 g/dl (range 7.3 – 9.9 g/dl). This study shows that it is possible to safely perform peri-acetabular osteotomies in most cases without blood transfusion which is important in this group of patients who are generally young and female


The Bone & Joint Journal
Vol. 97-B, Issue 12 | Pages 1604 - 1607
1 Dec 2015
Wassilew GI Perka C Janz V Krämer M Renner L

We have investigated the effect of using tranexamic acid (TXA) during peri-acetabular osteotomy (PAO) on peri-operative blood loss and blood transfusion requirements. In addition we analysed whether the use of TXA was associated with an increased risk of venous thromboembolism (VTE) following this procedure. A consecutive series of 96 PAOs, performed by a single surgeon, were reviewed. A total of 48 patients received TXA and 48 did not. The TXA group received a continuous infusion of TXA at a rate of 10 mg/kg/h. The primary outcome measure was the requirement for blood transfusion. Secondary outcomes included total blood loss, the decrease in the level of haemoglobin in the blood, the length of hospital stay, and the complications of this treatment. The mean rate of transfusion was significantly lower in the TXA group (62.5% vs 12.5%, p < 0.001). The mean blood loss was also significantly reduced in the TXA group (1.9 L (standard deviation (. sd. ) 0.9) vs 1.5 L (. sd. 0.7), p < 0.01). No post-operative episodes of VTE were identified in either group. . The use of TXA reduced the blood loss and the rate of transfusion after PAO significantly, without adverse effects such as an increased rate of VTE. Cite this article: Bone Joint J 2015;97-B:1604–7


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_3 | Pages 5 - 5
1 Apr 2015
Al Fakayh O Marsh A Patil S
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Ganz peri-acetabular osteotomy is commonly used to treat symptomatic hip dysplasia. It aims to increase the load bearing contact area of the hip to reduce the risk of subsequent osteoarthritis. In this study we assess the radiographic and clinical results of the procedure since its introduction to our unit. All patients undergoing Ganz osteotomies at our unit were followed up prospectively. Data collected included patient demographics and pre- and post-operative functional scores (Harris and Non-arthritic hip scores). In addition, acetabular correction was evaluated on pre-and post-operative radiographs (using Centre-Edge angle and Tonnis angle). Complications were also noted. Overall 50 procedures were performed between 2007 and 2013 with median follow-up of 3 years (1 – 7 years). The majority of patients (90%) were female. Average age at time of surgery was 29 years (16–49). There were significant improvements in pre- and post-operative median functional scores (Modified Harris Hip Score = 49 versus 64, p=0.001), Non-arthritic Hip Score = 42 versus 56, p=0.007). Median Centre Edge Angle improved from 16 degrees pre-operatively (range = 7–31 degrees) to 30 degrees post-operatively (18–33) degrees), p<0.0001. Similarly, pre-operative Tonnis angle improved from 18 degrees (9–38) to 7 degrees (2–14), p<0.0001. Five patients developed post-operative complications: 2 superficial wound infection, 1deep infection requiring hip washout and antibiotic treatment and 2 patients subsequently requiring total hip replacements. We have shown that the Ganz peri-acetabular osteotomy can be effective for the treatment of painful hip dysplasia improving both functional and radiographic outcomes. However, patient selection is a key factor


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_14 | Pages 11 - 11
1 Oct 2014
Marsh A Al Fakayh O Patil S
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Ganz peri-acetabular osteotomy is commonly used to treat symptomatic hip dysplasia. It aims to increase the load bearing contact area of the hip to reduce the risk of subsequent osteoarthritis. In this study we assess the radiographic and clinical results of the procedure since its introduction to our unit. All patients undergoing Ganz osteotomies at our unit were followed up prospectively. Data collected included patient demographics and pre- and post-operative functional scores (Harris and Non-arthritic hip scores). In addition, acetabular correction was evaluated on pre-and post-operative radiographs (using Centre-Edge angle and Tonnis angle). Complications were also noted. Overall 50 procedures were performed between 2007 and 2013 with median follow-up of 3 years (1–7 years). The majority of patients (90%) were female. Average age at time of surgery was 32 years (17–39). There were significant improvements in pre- and post-operative median functional scores (Modified Harris Hip Score = 52 versus 63, p=0.001), Non-arthritic Hip Score = 49 versus 60, p=0.01). Median Centre Edge Angle improved from 15 degrees pre-operatively (range = 8–19 degrees) to 29 degrees post-operatively (22–36 degrees), p=0.02. Similarly, pre-operative Tonnis angle improved from 19 degrees (16–38) to 7 degrees (2–14), p=0.01. Four patients developed post-operative complications: 1 superficial wound infection, 1deep infection requiring hip washout and antibiotic treatment and 2 patients subsequently requiring total hip replacements. We have shown that the Ganz peri-acetabular osteotomy can be effective for the treatment of painful hip dysplasia improving both functional and radiographic outcomes. However, patient selection is a key factor


The Journal of Bone & Joint Surgery British Volume
Vol. 67-B, Issue 3 | Pages 413 - 415
1 May 1985
Nielsen H Veth R Oldhoff J Koops H Scales J

We report a patient with a peri-acetabular chondrosarcoma which was treated by resection of part of the pelvis and the femoral head. This was followed by replacement with a custom-made titanium alloy pelvic portion and a conventional total hip prosthesis. The operation was carried out in two stages, and yielded a good functional and cosmetic result


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 97 - 97
1 Jan 2013
James C Hasan K Shah Z Wong F Bankes M
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Aims. To determine whether there is any benefit using a minimally invasive trans-sartorial approach as described by Professor Søballe compared to the ilio-femoral for peri-acetabular osteotomy. Methods. 30 consecutive patients were operated on by a single surgeon. The first 15 underwent an ilio-femoral (I-F) approach whilst the following 15 had a trans-sartorial (T-S) approach. Fixation was achieved with 3 or 4 screws. All other aspects of surgery and rehabilitation were the same. Data was collected prospectively and included operation time, intra-operative blood loss and length of stay. Acetabular correction was measured using the sourcil and centre edge angle (CEA) on pre and post-operative radiographs. Results. Both groups had acceptable radiographic corrections with CEA improving from mean 14.5 to 38.7 degrees (T-S) and 14 to 39 degrees (I-F). The sourcil angle improved from mean 17.8 to 2 degrees (T-S) and 19.5 to −1.5 (I-F). Minimally invasive surgery reduced anaesthetic time by 62 minutes. Haemoglobin loss was reduced by 1 gram/L and there was no requirement for transfusion. Hospital stay reduced by 0.8 days. There were no major adverse complications although two partial femoral neurapraxias were noted early in the series. These fully resolved. Conclusion. We have found significant benefit from changing to minimally invasive PAO. Our patients have smaller wounds, a shorter operative time, reduced bleeding and a shorter length of stay. We found no adverse effects. The time savings have also corresponded to a cost saving for our institution. We recommend this technique although recognise that it has a learning curve and should be initiated by surgeons with previous PAO experience


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 7 - 7
1 Jan 2004
Wixson R
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Since acetabular osteolytic lesions following total hip arthroplasty (THA) may be asymptomatic until extensive bone loss occurs, early detection and monitoring the progression of these lesions is important. The purpose of this study was to use high resolution helical CT to determine the progression of the osteolytic lesions over time by comparing serial studies. Fifty patients (Fifty-eight hips) with primary, cementless THA done between 1984–1996 were evaluated as part of an ongoing prospective study. These patients had a history of a high level of activity that was believed to place them at increased risk for accelerated polyethylene wear. The mean age was 51 yrs, 55% male:45% female. The average time from date of surgery to initial scan was 8.0 years (4.7–16.6). If an acetabular lytic lesion was identified, the patients were offered Alendronate for potential suppression of bone resorption with a repeat CT scan for follow-up. The area of the maximum size osteolytic lesions on axial images were measured on the initial scan and compared at the same level on the subsequent study. The interval between scans averaged 15 months (10 – 27). Progression was noted on 87% hips. The mean initial area was 328 mm2 (40–1084) with the follow-up area of 386 mm2 (46–1344) with a mean of progression of 15.7%. Once established, peri-acetabular lysis appears to be a slowly progressive, relentless process. Analysis of changes on serial CT, along with an assessment of the degree and location of lysis, provides an additional tool to evaluate the need for surgical intervention


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_22 | Pages 55 - 55
1 Dec 2016
Padgett D
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Periacetabular osteolysis is seen in response to particles (polyethylene, ceramic, metal or cement), at times in the presence of an unstable implant, and perhaps made worse by the unique host response to the particle burden. The impact of wear modes: due to either the primary bearing surface (MOP, MOM, COC) or unintended surfaces as seen in impingement, as well as the quality of the bearing counterface all influence the extent of the osteolytic response. The final common pathway appears to be via macrophage stimulation, an upregulation of cytokines leading to a resorption of bone.

The patterns of lysis range from linear resorption at the implant interface to more expansile patterns which can be more dramatic in size and may place the implant at jeopardy for loosening. Assessment of implant fixation as well as extent of the lytic process employs the use of plain radiographs (including oblique views), computerised tomography and magnetic resonance imaging. The utility of MRI for the quantification of bone loss as well as the newer phenomena of associated soft tissue lesions (pseudotumors, adverse tissue reactions) has turned out to be a valuable tool in helping determine timing and need for revision.

The basic principles in determining need for revision surgery revolve around: degree of lysis, integrity of the soft tissues, fixation of the implant, track record of the implant, as well as patient factors including symptoms, age and activity.

In cemented sockets, progressive bone loss, pain with or without overt loosening is indication for revision which is generally accomplished using an uncemented hemispherical acetabular component with bone graft and screw augmentation.

In the uncemented socket, the decision to revise is based upon a) implant stability, 2) the integrity of the locking mechanism, 3) degree of bone loss. With stable implants, polyethylene exchange and “lesional” treatment is appropriate. Well fixed implants with extensive lysis can be successfully managed with liner exchange and bone grafting as necessary. If the liner locking mechanism is compromised, cementing a liner into place is an excellent strategy. Removing a well fixed cup with extensive lysis runs the risk of encountering a large acetabular defect which may be difficult to reconstruct. Loose implants clearly require revision.

In the era of “hard bearings”, progressive soft tissue expansion leading to damage of the abductor and other soft tissue constraints about the hip is an indication for revision. Revision of MOM THR's may be performed by maintaining the femoral component and performing an isolated acetabular revision or in some instances of modular acetabular components, maintaining the shell and inserting a new liner. In all instances of implant retention, it is critical to confirm that the components are in optimised position: implants retained in suboptimal position are at risk for early failure.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_6 | Pages 3 - 3
1 May 2019
Thiagarajah S Verhaegen J Balijepalli P Bingham J Grammatopoulos G Witt J
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Introduction

The periacetabular osteotomy (PAO) improves hip joint mechanics in patients with symptomatic dysplasia. As a consequence of the multi-planar acetabular re-orientation, the course of the iliopsoas tendon over the hip may be affected, potentially resulting in iliopsoas tendon-related pain. At present, little information regarding the incidence of iliopsoas-related pathology following PAO exists.

We aimed to identify the incidence of iliopsoas-related pain following PAO. Secondarily, we aimed to identify any risk factors associated with this pathology.

Methods

We retrospectively reviewed the PAO's performed from 2014–2017, for symptomatic dysplasia in our unit (single-surgeon, minimum 1-year follow-up). All patients with adequate pelvic radiographs were included. Radiographic parameters of dysplasia were measured from pre- and post-operative AP pelvic radiographs using a validated software (SHIPS)1. The degree of pubis displacement was classified according to our novel system. Cases were defined as those with evidence of iliopsoas-related pain post PAO (positive response to iliopsoas tendon-sheath steroid/local anaesthetic injection).


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_13 | Pages 103 - 103
1 Nov 2015
Maloney W
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With cementless porous-coated acetabular replacements, extensive bone loss can occur without effecting implant stability. As a result, the surgeon is frequently faced with re-operating on a well-fixed cementless acetabular component with osteolysis and must decide whether or not to remove a well-fixed porous coated socket. A classification system and treatment algorithm has been developed to aid in management decisions regarding re-operation for polyethylene wear and pelvic osteolysis.

Cases are classified into one of 3 possible categories depending on the radiographic stability of the porous coated shell and the ability to replace the polyethylene liner. Type I case; stable porous coated shell, liner replaceable; Type II case; socket stable, liner not replaceable;

Type III case; socket loose, not osseointegrated.

Treatment Algorithms - Retain well-fixed shell in Type I cases and replace the liner. Debride accessible lytic lesions and graft with allograft chips. Remove the well-fixed shell in Type II case. Assess defect once the shell is removed. Reconstruction based on the bony defect present. The vast majority can be revised with a larger porous coated socket. Remove loose socket in Type III cases. Assess defect and reconstruct based on the defect. There is a greater need for more extensive grafting and the use of reconstruction rings with Type III cases.

This treatment algorithm has helped the authors successfully evaluate and treat a large series of patients with polyethylene wear and pelvic osteolysis in association with porous coated acetabular components. The stability of the acetabular component and appropriate knowledge of the implant are important factors that impact surgical management.