Advertisement for orthosearch.org.uk
Results 1 - 20 of 70
Results per page:
Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_3 | Pages 77 - 77
23 Feb 2023
Bolam S Konar S Gamble G Paine S Dalbeth N Monk A Coleman B Cornish J Munro J Musson D
Full Access

Traumatic rotator cuff injuries can be a leading cause of prolonged shoulder pain and disability, and contribute to significant morbidity and healthcare costs. Previous studies have shown evidence of socio-demographic disparities with these injuries. The purpose of this nationwide study was to better understand these disparities based on ethnicity, sex, and socio-economic status, in order to inform future healthcare strategies.

Accident Compensation Corporation (ACC) is a no-fault comprehensive compensation scheme encompassing all of Aotearoa/New Zealand (population in 2018, 4.7 million). Using the ACC database, traumatic rotator cuff injuries were identified between January 2010 and December 2018. Injuries were categorized by sex, ethnicity, age and socioeconomic deprivation index of the claimant.

During the 9-year study period, there were 351,554 claims accepted for traumatic rotator cuff injury, which totalled over $960 million New Zealand Dollars. The greatest proportion of costs was spent on vocational support (49.8%), then surgery (26.3%), rehabilitation (13.1%), radiology (8.1%), general practitioner (1.6%) and “Other” (1.1%). Asian, Māori (Indigenous New Zealanders), and Pacific peoples were under-represented in the age-standardized proportion of total claims and had lower rates of surgery than Europeans. Māori had higher proportion of costs spent on vocational support and lower proportions spent on radiology, rehabilitation and surgery than Europeans. Males had higher number and costs of claims and were more likely to have surgery than females. There were considerably fewer claims from areas of high socio-economic deprivation.

This large nation-wide study demonstrates the important and growing economic burden of rotator cuff injuries. Indirect costs, such as vocational supports, are a major contributor to the cost suggesting improving treatment and rehabilitation protocols would have the greatest economic impact. This study has also identified socio-demographic disparities which need to be addressed in order to achieve equity in health outcomes.


The Bone & Joint Journal
Vol. 106-B, Issue 10 | Pages 1182 - 1189
1 Oct 2024
Nisar S Lamb J Johansen A West R Pandit H

Aims

To determine if patient ethnicity among patients with a hip fracture influences the type of fracture, surgical care, and outcome.

Methods

This was an observational cohort study using a linked dataset combining data from the National Hip Fracture Database and Hospital Episode Statistics in England and Wales. Patients’ odds of dying at one year were modelled using logistic regression with adjustment for ethnicity and clinically relevant covariates.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 44 - 44
1 Feb 2017
Bischoff J Brownhill S Snyder S Rippstein P Philbin T Coetzee J
Full Access

Introduction/Purpose

Total ankle replacement (TAR) success has improved since first-generation implants, but patient satisfaction continues to be less than knee and hip replacements. Little is known about variations in distal tibia anatomy between genders and across ethnicities; therefore it is unclear the extent to which current TAR prostheses accommodate variability in patient size and shape. This study quantified distal tibia morphometrics relevant to TAR design, and assessed differences between ethnicities and genders. The hypotheses were: (1) The anterior-posterior (AP) location of the dwell point of the tibia is centralized; (2) The sagittal radius of curvature of the tibial articulation increases with bone size; (3) Differences in dwell point location or sagittal radii between genders and ethnicities can be attributed to size differences between those populations.

Methods

Tibial CT scans were obtained from cadavers or individuals of various ethnicities (Table 1). Landmarks were defined on digital models created from the scans, including medial and lateral edges of the distal tibial articulation (Figure 1a), and sagittal contours of the articulation (Figure 1b). The articulation center was defined as the average center point of all contours (Figure 1c). The AP center and AP length at the level of a distal tibial resection for TAR were determined, and the AP offset of the articulation center was calculated (Figure 1c). Differences in metrics for each ethnic and gender group were determined using a one-way Anova (P<.05) with Tukey's method for differentiating groups. Regression fits of AP offset, average medial radius, and average lateral radius were determined. Utilizing AP length as a covariate, ANCOVA was utilized to assess differences in AP offset and sagittal radii between gender and ethnic groups (P<.05).


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 137 - 137
1 Feb 2020
Dessinger G Argenson J Bizzozero P LaCour M Komistek R
Full Access

Introduction

Numerous fluoroscopic studies have been conducted to investigate kinematic variabilities of total knee arthroplasty (TKA). In those studies, subjects having a posterior stabilized (PS) TKA experience greater weightbearing knee flexion and posterior femoral rollback of the lateral condyle. In those same studies, subjects did experience a high incidence of variable medial condyle motion and reverse axial rotation, especially occurring when the cam engaged the post. More recently, a PS TKA was designed to accommodate both gender and ethnicity. Therefore, the objective of this study was to assess in vivo kinematics for subjects having this TKA type to determine if subjects having this PS TKA experienced more optimal knee kinematics.

Methods

Twenty-five subjects in this study were asked to perform a deep knee bend to maximum knee flexion and a step-up maneuver while under fluoroscopic surveillance. All subjects were patients of one experienced surgeon and received the same PS TKA. Using a 3D-2D registration technique, the CAD models, supplied by the sponsoring company, were superimposed over x-ray images at specified increments throughout the fluoroscopic footage. The kinematics were then analyzed to evaluate lateral anterior/posterior (LAP) and medial anterior/posterior (MAP) condyle translation as well as axial rotation of the femur with respect to the tibia.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 193 - 193
1 Mar 2010
Mangelson JJ Osadebe UC Noble PC Harrington M Parsley P
Full Access

Introduction: There is an increasing appreciation of the potential impact of ethnic and gender diversity on access to healthcare. Previous studies have shown that both race and gender are important confounding factors. In this study we isolate the influence of ethnicity on the functional outcome of total knee replacement by examining outcomes in female patients.

Materials and Methods: We reviewed a data-base of 412 female patients (518 knees) who had undergone primary TKA performed by a single surgeon between 1990 and 2008. Eighty-seven of these patients (25 African-American, 23 Hispanic and 26 Caucasian patients) were case-matched for age and BMI at the time of surgery. The average patient age was 67.0 years with a BMI of 32.0. The groups showed no statistical different in age (p=0.99) or BMI (p=0.90). Preoperative and postoperative Knee Society scores were available on all patients in addition to marital status. Outcome measures of all three groups were compared using ANOVA statistical methods with post hoc analysis.

Results: Post-op Knee Society Scores were Significantly lower in the African-American patients (76.2, p=0.02) than the Hispanic (85.1) and Caucasian (87.9) groups. There was also a Significant difference in post-op pain scores for African-American, Hispanic, and Caucasian patients were 32.2, 40.3, and 42.8 respectively, (p=0.02) showing a statistically Significant difference between groups. The average Function Score was also lower in both African-American (61.1) and Hispanic (63.3) groups when compared to Caucasian (72.1) but this difference was not statistically Significant (p=0.09, p=0.25). There was no Significant difference in preoperative knee scores, post-op ROM or stability, or marital status among the three groups (p > .05).

Discussion:

Within the female population, ethnicity was shown to have a Significant influence on the outcome of TKA as inferior results were reported by both Hispanic and African-American patients when compared to Caucasians. This effect is particularly marked in African-American women whose Knee Society Scores were 13% lower at follow-up compared to Caucasians.

The differences in the perception of pain noted by the various ethnic groups proved to be a principal factor for outcomes following TKA among women.

This study demonstrates that the ethnicity must be considered in assessing outcomes. Within the female population TKA appears to be less successful in Hispanic and African-American patients.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 451 - 451
1 Nov 2011
Leszko F Hovinga K Mahfouz M Lerner A Anderle M Komistek R
Full Access

Previous in vivo studies have not documented if ethnicity or gender influence knee kinematics for the healthy knee joint. Other measurements, such as hip-knee-ankle alignment have been previously shown to be significantly different between females and males, as well as Japanese and Caucasian populations in the young healthy knee [1]. Differences in knee kinematics in high flexion positions may relate to both etiology of osteoarthritis and success in knee replacement designs. Although differences in knee anatomy have been identified, their significance in knee function has not yet been clarified. Therefore, the objective of this study was to determine the 3D, in vivo normal knee kinematics for various subjects from different gender and ethnic backgrounds, and to identify significant differences, if any, between populations.

The 3D, in vivo, weight bearing normal knee kinematics was determined for 79 healthy subjects, including 48 Caucasians, 24 Japanese, 42 males, and 37 females. Each participant performed deep knee bend activity from a standing (full extension) to squatting to a lunge motion, until maximum knee flexion was reached. The study was approved by the Institutional Review Board and informed consent form was obtained from all subjects. The 3D bone models, created by segmentation from MR images, were used to recreate the 3D knee kinematics using the previously described fluoroscopic and 3D-to-2D registration techniques (Fig. 1) [2,3]. Tibiofemoral rotations were described using the ISB recommended Grood and Suntay convention [4,5]. Anterior-posterior translations of the centers of the posterior femoral condyles were normalized due to significantly different anthropometry in the subjects. Anterior cruciate ligament (ACL) laxity was also measured using a KT-1000 device for 72 of these subjects. Statistical analysis was performed using the Student’s t-test, set at the 95% confidence interval.

Most subjects achieved very high flexion, however substantial variability occurred in all groups. Range of motion (ROM) varied from 117° to 177°, while average external rotation was 31°± 9.9° for all subjects. Japanese and female subjects achieved greater ROM than Caucasian (p=0.048) and male (p=0.014) subjects. From full extension to 140° of flexion (which 87% of subjects achieved), few significant differences between any of the populations were observed. At deeper flexion, the external rotation was higher for female than for male subjects, however not statistically significant (p=0.0564 at 155°). Also at deep flexion, the adduction was significantly higher for female subjects. The translations of the lateral condyle were very similar between respective groups, but at deep flexion, the medial condyle remained significantly more anterior for females, leading to greater axial rotation and ROM. As ACL laxity increased, flexion/extension ROM significantly increased (r2=0.184, p< 0.001). In addition, ACL laxity was also higher for females (6.8 mm) compared to males (5.6 mm, p=0.011), as well as Japanese (7.5 mm) compared to Caucasian (5.6 mm, p=0.0002) subjects.

High variability and ROM in knee kinematics were similar to those seen in previous studies of healthy subjects during a deep knee bending activity [6]. Subjects in this study achieved much greater axial rotation and ROM than previously analyzed TKA patients. A relationship was found between greater axial rotation and increased ROM, and may be related in part to increased ACL laxity in the knee. Significant differences in ROM and laxity were identified between genders and ethnic groups. Also the medial condyle remaining significantly more anterior for females than for males in deep flexion may explain higher external rotation and consequently higher flexion experienced by women. However, understanding the causes for variability within each group may be the key to improved implant design.


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_8 | Pages 8 - 8
10 May 2024
Sim K Schluter D Sharp R
Full Access

Introduction. Acetabular component loosening with associated bone loss is a challenge in revision hip arthroplasty. Trabecular Metal (TM) by Zimmer Biomet has been shown to have greater implant survivorship for all-cause acetabular revision in small cohort retrospective studies. Our study aims to review outcomes of acetabular TM implants locally. Method. This is a retrospective observational study using data from Auckland City and North Shore Hospitals from 1st of January 2010 to 31st of December 2020. Primary outcome is implant survivorship (re-revision acetabular surgery for any cause) demonstrated using Kaplan-Meier analysis. Secondary outcome is indication for index revision and re-revision surgery. Multivariate analysis used to identify statistically significant factors for re-revision surgery. Results. 225 cases used acetabular TM implants (shells and/or augments) over 10 years. Indications include aseptic loosening (63%), instability (15%) and infection (13%). Of these, 12% (n=28) had further re-revision for infection (54%) and instability (21%). Median time to re-revision was 156 days (range 11 – 2022). No cases of re-revision were due to failure of bony ingrowth or acetabular component loosening. Ethnicity, smoking status, and age were not risk factors for re-revision procedures. Additionally, previous prosthetic joint infection, ethnicity, sex and age were not significant risk factors for re-revision due to infection. Implant survivorship was 80% at 1 year, 71% at 5 years and 64% at 10 years. Discussion. Main indications for re-revision were infection and instability. Demographic factors and co-morbidities did not correlate with increased re-revision risk. Survivorship is poorer compared to cumulative survivorship reported by the New Zealand Joint Registry (NZJR). Explanations are multifactorial and possibly contributed by underestimation of true revision rates by registry data. Conclusions. We need to identify alternate causes for poorer survivorship and review the role of TM implants in acetabular revision within our specified population


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_15 | Pages 16 - 16
7 Aug 2024
Ridgway L Koushesh S Tachrount M Probert F Martin K Scott W Crombez G Price C Robinson C Clare S Fairbank J Baskozos G Schmid A
Full Access

Background. FORECAST is a prospective longitudinal cohort study exploring mechanism-based prognostic factors for pain persistence in sciatica. Here, we share an update on this largest deeply-phenotyped primary care sciatica cohort. Methods/results. Our cohort includes 180 people with sciatica (score >4 on Stynes’ Sum Score), aged 18–85, within 3 months of symptom onset. Psychosocial factors, self-reported sensory profiling, clinical examination, quantitative sensory testing (QST), biological samples (blood and skin samples), and Magnetic Resonance Neurography of lumbar nerve roots were collected at baseline. Pain persistence was determined at three and twelve months with the Sciatica Bothersomeness Index (SBI) and a numeric pain rating scale (NRS) as primary outcomes. Recruitment nears completion, with 160 participants enrolled to date. 127 and 96 participants have completed 3 and 12 months follow-up respectively. Overall, 56% of our cohort are female, with a mean age (SD) of 54.14yrs (16.57). Ethnicity data approximates local populations. SBI at baseline was (median [IQR]) 13[10-17], and interim longitudinal data shows stepwise improvement at 3 and 12 months. Baseline ‘average’ pain intensity was 5.56 (2.15) for leg pain, and 4.14(2.82) for low back pain (LBP). Overall, pain scores decreased at 3 and 12 months, with greater reductions in leg pain than LBP at 12 months. However, around 55–80% and 40–65% of people reported persistent pain at 3 and 12 months respectively. Conclusion. Leg pain severity was moderate and higher than LBP at baseline. All primary outcome measures demonstrate improvement over time, however 40–65% of patients report persistent pain at 12 months. Conflicts of interest. LR: Paid facilitation of post-graduate courses internationally. SK, MT, FP, KM, WS, CP, CR, SC: No conflicts of interest. GC: Editor in Chief of Health Psychology Review. Director of board of directors, MentalCHealth Care setting NoordWestVlaanderen. JF: Copyright holder of ODI (Oswestry Disability Index). Served on a data monitoring committee for a clinical trial of 2 different surgical approaches to cervical disc herniation (FORVAD). Member of HTA Prioritisation Committee B: Inside hospital Care from 2015-February 2019. Member of HTA Interventional Procedures Panel from 2010–2015. Trustee and board member of 3 spine related charities – Back to Back; British Scoliosis Research Foundation and BackCare. Expert instructed by both claimant and defendant solicitors in negligence and person injury cases. GB: Paid consultancy (RNA-seq) with Ivy Farm and Coding.bio. ABS: Paid post-graduate lecturing internationally. Co-chair NeupSig sciatica working group (unpaid). Sources of funding. This project is funded by UKRI and Versus Arthritis as part of the UKRI Strategic Priorities Fund (SPF) Advanced Pain Discovery Platform (APDP), a co-funded initiative by UKRI (MRC, BBSRC, ESRC), Versus Arthritis, the Medical Research Foundation and Eli Lilly and Company Ltd (Grant MR/W027003/1). Additional funding has been received from the back to back charity to expand longitudinal components of the study. LR has received support with PhD fees from the CSP charitable trust. ABS is supported by a Wellcome Trust Clinical Career Development Fellowship. (222101/Z/20/Z). WS is partly funded through the National Institute for Health and Care Research (NIHR) Biomedical Research Centre at the South London and Maudsley NHS Foundation Trust and King's College London. FP is funded by a Dorothy Hodgkin Career Development Fellowship in Chemistry in association with Somerville College. GB is supported by the Wellcome Trust (223149/Z/21/Z) and Diabetes UK (19/0005984). GC and KRM are partly funded by UKRI and Versus Arthritis as part of the Advanced Pain Discovery Platform (APDP) PAINSTORM (MR/W002388/1). The UKRI and Versus Arhthritis (APDP) are the major funders of FORECAST. All other funders provided either some people support, or funded projects with legacy data that we reuse


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_23 | Pages 52 - 52
1 Dec 2016
McBride S Mowbray J Caughey W Wong E Luey C Siddiqui A Alexander Z Playle V Askelund T Hopkins C Quek N Ross K Holland D
Full Access

Aim. To describe the epidemiology, clinical features and outcomes of native joint septic arthritis in adults admitted to Middlemore Hospital in Auckland, New Zealand. Method. Single-centre retrospective cohort study from 2009 to 2014. Patients ≥16 years of age were identified using ICD-10AM coding data. Electronic records were reviewed for demographic, clinical, laboratory, treatment and outcome data. Total and hemi-arthroplasty infections were excluded. Results. 543 episodes in 521 patients were included, with 90% fulfilling Modified Newman's criteria. Septic arthritis incidence was 26/100,000 patient years and was unchanged over the study period. Incidence correlated strongly with age (R. 2. =0.79) and socioeconomic deprivation (R. 2. =0.76). Median age was 49 years, and gender 70% male. Ethnicity was Pacific Island in 36% (22.8% of catchment population). The most commonly involved joints were hand interphalangeal (19%), knee (19%), metacarpophalangeal (17%) and glenohumeral (11%). Arthritis was monoarticular in 93%. Underlying conditions included current smoking (42%), osteoarthritis (29%), diabetes (22%) and gout (15%). Rheumatoid and seronegative arthritis were uncommon (each 2%). Skin/soft tissue infection occurred within 3 months prior in 38%. Osteomyelitis occurred in 26%. Sources of infection included haematogenous (42%), traumatic (34%), and iatrogenic (17%). Causative organism(s) were isolated in 80% of episodes, most commonly Staphylococcus aureus (53%, 13% of which were MRSA) then Streptococcus pyogenes (15%). 28% of culture-positive episodes were polymicrobial. Median antibiotic duration was 4 weeks, with 38% having definitive therapy orally. A median of 1 surgical procedure was undertaken during treatment. Mortality at 30 days was 3%, at 90 days 5% and treatment failure (defined as any of: death <90 days; relapse; reinfection; or ongoing joint infection leading to readmission, amputation, arthrodesis or excision arthroplasty) occurred in 17%. Treatment failure was significantly more common in cases involving large joints (23%, (69/302) vs. 11%, (26/241), p=0.0002) and in haematogenous episodes versus traumatic episodes (21% (47/229) vs. 10% (19/168), p=0.0045). Conclusions. This is the largest series of adult native joint septic arthritis currently available. The extremely high observed septic arthritis incidence (26/100,000 person years) may relate to high rates of skin and soft tissue infection in Auckland, particularly among Pacific people. Small joint infection, often excluded from previous studies, is associated with significantly better outcomes than large-joint infection. Mortality is lower in this cohort than previously reported, possibly due to the inclusion of small joint infections and exclusion of prosthetic joint infections. Acknowledgements. No additional funding was received for this work


Bone & Joint Open
Vol. 5, Issue 8 | Pages 697 - 707
22 Aug 2024
Raj S Grover S Spazzapan M Russell B Jaffry Z Malde S Vig S Fleming S

Aims

The aims of this study were to describe the demographic, socioeconomic, and educational factors associated with core surgical trainees (CSTs) who apply to and receive offers for higher surgical training (ST3) posts in Trauma & Orthopaedics (T&O).

Methods

Data collected by the UK Medical Education Database (UKMED) between 1 January 2014 and 31 December 2019 were used in this retrospective longitudinal cohort study comprising 1,960 CSTs eligible for ST3. The primary outcome measures were whether CSTs applied for a T&O ST3 post and if they were subsequently offered a post. A directed acyclic graph was used for detecting confounders and adjusting logistic regression models to calculate odds ratios (ORs), which assessed the association between the primary outcomes and relevant exposures of interest, including: age, sex, ethnicity, parental socioeconomic status (SES), domiciliary status, category of medical school, Situational Judgement Test (SJT) scores at medical school, and success in postgraduate examinations. This study followed STROBE guidelines.


The Bone & Joint Journal
Vol. 106-B, Issue 11 | Pages 1312 - 1320
1 Nov 2024
Hamoodi Z Sayers A Whitehouse MR Rangan A Kearsley-Fleet L Sergeant J Watts AC

Aims

The aim of this study was to review the provision of total elbow arthroplasties (TEAs) in England, including the incidence, the characteristics of the patients and the service providers, the types of implant, and the outcomes.

Methods

We analyzed the primary TEAs recorded in the National Joint Registry (NJR) between April 2012 and December 2022, with mortality data from the Civil Registration of Deaths dataset. Linkage with Hospital Episode Statistics-Admitted Patient Care (HES-APC) data provided further information not collected by the NJR. The incidences were calculated using estimations of the populations from the Office for National Statistics. The annual number of TEAs performed by surgeons and hospitals was analyzed on a national and regional basis.


The Bone & Joint Journal
Vol. 106-B, Issue 3 | Pages 232 - 239
1 Mar 2024
Osmani HT Nicolaou N Anand S Gower J Metcalfe A McDonnell S

Aims

To identify unanswered questions about the prevention, diagnosis, treatment, and rehabilitation and delivery of care of first-time soft-tissue knee injuries (ligament injuries, patella dislocations, meniscal injuries, and articular cartilage) in children (aged 12 years and older) and adults.

Methods

The James Lind Alliance (JLA) methodology for Priority Setting Partnerships was followed. An initial survey invited patients and healthcare professionals from the UK to submit any uncertainties regarding soft-tissue knee injury prevention, diagnosis, treatment, and rehabilitation and delivery of care. Over 1,000 questions were received. From these, 74 questions (identifying common concerns) were formulated and checked against the best available evidence. An interim survey was then conducted and 27 questions were taken forward to the final workshop, held in January 2023, where they were discussed, ranked, and scored in multiple rounds of prioritization. This was conducted by healthcare professionals, patients, and carers.


The Bone & Joint Journal
Vol. 106-B, Issue 2 | Pages 174 - 181
1 Feb 2024
Mandalia KP Brodeur PG Li LT Ives K Cruz Jr. AI Shah SS

Aims

The aim of this study was to characterize the influence of social deprivation on the rate of complications, readmissions, and revisions following primary total shoulder arthroplasty (TSA), using the Social Deprivation Index (SDI). The SDI is a composite measurement, in percentages, of seven demographic characteristics: living in poverty, with < 12 years of education, single-parent households, living in rented or overcrowded housing, households without a car, and unemployed adults aged < 65 years.

Methods

Patients aged ≥ 40 years, who underwent primary TSA between 2011 and 2017, were identified using International Classification of Diseases (ICD)-9 Clinical Modification and ICD-10 procedure codes for TSA in the New York Statewide Planning and Research Cooperative System database. Readmission, reoperation, and other complications were analyzed using multivariable Cox proportional hazards regression controlling for SDI, age, ethnicity, insurance status, and Charlson Comorbidity Index.


Bone & Joint Open
Vol. 4, Issue 3 | Pages 168 - 181
14 Mar 2023
Dijkstra H Oosterhoff JHF van de Kuit A IJpma FFA Schwab JH Poolman RW Sprague S Bzovsky S Bhandari M Swiontkowski M Schemitsch EH Doornberg JN Hendrickx LAM

Aims

To develop prediction models using machine-learning (ML) algorithms for 90-day and one-year mortality prediction in femoral neck fracture (FNF) patients aged 50 years or older based on the Hip fracture Evaluation with Alternatives of Total Hip arthroplasty versus Hemiarthroplasty (HEALTH) and Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trials.

Methods

This study included 2,388 patients from the HEALTH and FAITH trials, with 90-day and one-year mortality proportions of 3.0% (71/2,388) and 6.4% (153/2,388), respectively. The mean age was 75.9 years (SD 10.8) and 65.9% of patients (1,574/2,388) were female. The algorithms included patient and injury characteristics. Six algorithms were developed, internally validated and evaluated across discrimination (c-statistic; discriminative ability between those with risk of mortality and those without), calibration (observed outcome compared to the predicted probability), and the Brier score (composite of discrimination and calibration).


The Bone & Joint Journal
Vol. 104-B, Issue 10 | Pages 1156 - 1167
1 Oct 2022
Holleyman RJ Khan SK Charlett A Inman DS Johansen A Brown C Barnard S Fox S Baker PN Deehan D Burton P Gregson CL

Aims

Hip fracture commonly affects the frailest patients, of whom many are care-dependent, with a disproportionate risk of contracting COVID-19. We examined the impact of COVID-19 infection on hip fracture mortality in England.

Methods

We conducted a cohort study of patients with hip fracture recorded in the National Hip Fracture Database between 1 February 2019 and 31 October 2020 in England. Data were linked to Hospital Episode Statistics to quantify patient characteristics and comorbidities, Office for National Statistics mortality data, and Public Health England’s SARS-CoV-2 testing results. Multivariable Cox regression examined determinants of 90-day mortality. Excess mortality attributable to COVID-19 was quantified using Quasi-Poisson models.


Bone & Joint Open
Vol. 5, Issue 1 | Pages 53 - 59
19 Jan 2024
Bialaszewski R Gaddis J Laboret B Bergman E Mulligan EP LaCross J Stewart A Wells J

Aims

Social media is a popular resource for patients seeking medical information and sharing experiences. periacetabular osteotomy (PAO) is the gold-standard treatment for symptomatic acetabular dysplasia with good long-term outcomes. However, little is known regarding the perceived outcomes of PAO on social media. The aims of this study were to describe the perceived outcomes following PAO using three social media platforms: Facebook, Instagram, and X (formerly known as Twitter).

Methods

Facebook, Instagram, and X posts were retrospectively collected from 1 February 2023. Facebook posts were collected from the two most populated interest groups: “periacetabular osteotomy” and “PAO Australia.” Instagram and X posts were queried using the most popular hashtags: #PAOwarrior, #periacetabularosteotomy, #periacetabularosteotomyrecovery, #PAOsurgery, and #PAOrecovery. Posts were assessed for demographic data (sex, race, location), perspective (patient, physician, professional organization, industry), timing (preoperative vs postoperative), and perceived outcome (positive, negative, neutral).


The Bone & Joint Journal
Vol. 106-B, Issue 6 | Pages 582 - 588
1 Jun 2024
Bertram W Howells N White SP Sanderson E Wylde V Lenguerrand E Gooberman-Hill R Bruce J

Aims

The aim of this study was to describe the prevalence and patterns of neuropathic pain over one year in a cohort of patients with chronic post-surgical pain at three months following total knee arthroplasty (TKA).

Methods

Between 2016 and 2019, 363 patients with troublesome pain, defined as a score of ≤ 14 on the Oxford Knee Score pain subscale, three months after TKA from eight UK NHS hospitals, were recruited into the Support and Treatment After Replacement (STAR) clinical trial. Self-reported neuropathic pain and postoperative pain was assessed at three, nine, and 15 months after surgery using the painDETECT and Douleur Neuropathique 4 (DN4) questionnaires collected by postal survey.


The Bone & Joint Journal
Vol. 104-B, Issue 11 | Pages 1202 - 1208
1 Nov 2022
Klasan A Rice DA Kluger MT Borotkanics R McNair PJ Lewis GN Young SW

Aims

Despite new technologies for total knee arthroplasty (TKA), approximately 20% of patients are dissatisfied. A major reason for dissatisfaction and revision surgery after TKA is persistent pain. The radiological grade of osteoarthritis (OA) preoperatively has been investigated as a predictor of the outcome after TKA, with conflicting results. The aim of this study was to determine if there is a difference in the intensity of pain 12 months after TKA in relation to the preoperative radiological grade of OA alone, and the combination of the intensity of preoperative pain and radiological grade of OA.

Methods

The preoperative data of 300 patients who underwent primary TKA were collected, including clinical information (age, sex, preoperative pain), psychological variables (depression, anxiety, pain catastrophizing, anticipated pain), and quantitative sensory testing (temporal summation, pressure pain thresholds, conditioned pain modulation). The preoperative radiological severity of OA was graded according to the Kellgren-Lawrence (KL) classification. Persistent pain in the knee was recorded 12 months postoperatively. Generalized linear models explored differences in postoperative pain according to the KL grade, and combined preoperative pain and KL grade. Relative risk models explored which preoperative variables were associated with the high preoperative pain/low KL grade group.


Bone & Joint Open
Vol. 4, Issue 11 | Pages 873 - 880
17 Nov 2023
Swaby L Perry DC Walker K Hind D Mills A Jayasuriya R Totton N Desoysa L Chatters R Young B Sherratt F Latimer N Keetharuth A Kenison L Walters S Gardner A Ahuja S Campbell L Greenwood S Cole A

Aims

Scoliosis is a lateral curvature of the spine with associated rotation, often causing distress due to appearance. For some curves, there is good evidence to support the use of a spinal brace, worn for 20 to 24 hours a day to minimize the curve, making it as straight as possible during growth, preventing progression. Compliance can be poor due to appearance and comfort. A night-time brace, worn for eight to 12 hours, can achieve higher levels of curve correction while patients are supine, and could be preferable for patients, but evidence of efficacy is limited. This is the protocol for a randomized controlled trial of ‘full-time bracing’ versus ‘night-time bracing’ in adolescent idiopathic scoliosis (AIS).

Methods

UK paediatric spine clinics will recruit 780 participants aged ten to 15 years-old with AIS, Risser stage 0, 1, or 2, and curve size (Cobb angle) 20° to 40° with apex at or below T7. Patients are randomly allocated 1:1, to either full-time or night-time bracing. A qualitative sub-study will explore communication and experiences of families in terms of bracing and research. Patient and Public Involvement & Engagement informed study design and will assist with aspects of trial delivery and dissemination.


The Bone & Joint Journal
Vol. 105-B, Issue 4 | Pages 382 - 388
15 Mar 2023
Haque A Parsons H Parsons N Costa ML Redmond AC Mason J Nwankwo H Kearney RS

Aims

The aim of this study was to compare the longer-term outcomes of operatively and nonoperatively managed patients treated with a removable brace (fixed-angle removable orthosis) or a plaster cast immobilization for an acute ankle fracture.

Methods

This is a secondary analysis of a multicentre randomized controlled trial comparing adults with an acute ankle fracture, initially managed either by operative or nonoperative care. Patients were randomly allocated to receive either a cast immobilization or a fixed-angle removable orthosis (removable brace). Data were collected on baseline characteristics, ankle function, quality of life, and complications. The Olerud-Molander Ankle Score (OMAS) was the primary outcome which was used to measure the participant’s ankle function. The primary endpoint was at 16 weeks, with longer-term follow-up at 24 weeks and two years.