Prosthetic Hip dislocations remain one of the most common major complications after total hip arthroplasty procedures, which has led to much debate and refinement geared to the optimization of implant and bearing options, surgical approaches, and technique. The implementation of larger femoral heads has afforded patients a larger excursion distance and primary arc range motion before impingement, leading to lowered risk of hip dislocation. However, studies suggest that while the above remains true, the use of larger heads may contribute to increased volumetric wear, trunnion related corrosion, and an overall higher prevalence of loosening, pain, and patient dissatisfaction, which may require revision hip arthroplasty. More novel designs such as the dual mobility hip have been introduced into the United States to optimize stability and range of motion, while possibly lowering the frictional torque and modes of failure associated with larger fixed bearing articulations. Therefore, the aim of this study is to compare the effect of bearing design and anatomic angles on frictional torque using a clinically relevant model8. Two bearing designs at various anatomical angles were used; a fixed and a mobile acetabular component at anatomical angles of 0°,20°,35°,50°, and 65°. The fixed design consisted of a 28/56mm inner diameter/outer diameter acetabular hip insert that articulated against a 28mm CoCr femoral head (n=6). The mobile design consisted of a 28mm CoCr femoral head into a 28/56mm inner diameter/outer diameter polyethylene insert that articulates against a 48mm metal shell (n=6). The study was conducted dynamically following a physiologically relevant frictional model8. A statistical difference was found only between the anatomical angles comparison of 0vs65 degrees in the mobile bearing design. In the fixed bearing design, a statistical difference was found between the anatomical angles comparison of 20vs35 degrees, 20vs50 degrees, and 35vs65 degrees. No anatomical angle effect on frictional torque between each respective angle or bearing design was identified. Frictional torque was found to decrease as a function of anatomical angle for the fixed bearing design (R2=0.7347), while no difference on frictional torque as a function of anatomical angle was identified for the mobile bearing design. (R2=0.0095). These results indicate that frictional torque for a 28mm femoral head is not affected by either anatomical angle or bearing design. This data suggests that mobile design, while similar to the 28mm fixed bearing, may provide lower frictional torque when compared to larger fixed bearings >or= 32mm8. Previous work by some of the authors [8] show that frictional torque increases as a function of femoral head size. Therefore, this option may afford surgeons the ability to achieve optimal hip range of motion and stability, while avoiding the reported complications associated with using larger fixed bearing heads8. It is important to understand that frictional behavior in hip bearings may be highly sensitive to many factors such as bearing clearance, polyethylene thickness/stiffness, polyethylene thickness/design, and host related factors, which may outweigh the effect of bearing design or cup abduction angle. These factors were not considered in this study

Introduction. Total-knee-arthroplasty (TKA) is a well-established method to restore the joint function of the human knee. Different types of TKA designs are clinically available which can be divided in two main groups, the posterior-cruciate- ligament (PCL) sacrificing and retaining group. However, pre-operatively it is often difficult to plan for one or the other. Therefore, the research question was: Is it possible to develop a TKA bearing design which works for both the cruciate sacrificing and retaining technique? A medial-congruent (MC) bearing design was developed, characterized by a high medial sagittal conformity and lower lateral sagittal conformity, which can be used for both cruciate ligament states. This study compares the laxity and kinematics of this MC design to a contemporary PS design for the cruciate sacrificing technique and to a contemporary CR design for the cruciate retaining technique. Methods. Four specimen-specific computer models of the human knee, consisting of a femur, tibia and fibula bone as well as the contribution of the ligaments and capsule, were virtually implanted with three TKA designs in four constellations: 1) MC without PCL, 2) MC with PCL, 3) contemporary PS without PCL and 4) contemporary CR with PCL following the design specific surgical technique and tibia slopes. Laxity tests in internal-external rotation (moment ± 4 Nm) were performed with the implanted models for a weight bearing case (500N compression). In addition, a high demanding activity (lunge) was simulated. The resulting averaged laxities and kinematics were analysed and compared to each other. Results. When sacrificing the PCL, MC showed lower medial laxity throughout flexion and higher lateral laxity above 60° flexion compared to the PS design. When retaining the PCL, the MC resulted in lower medial laxity throughout flexion, lower lateral laxity in extension and similar lateral laxity in flexion compared to the CR design. When sacrificing the PCL in the lunge activity, the MC design had a more posterior position throughout flexion on both condyles until deep flexion when the engagement of the cam/spine occurred for the PS design and posterior motion of the medial condyle during mid-flexion as opposed to anterior motion for the PS design. When retaining the PCL in the lunge-activity, the MC design had a more posterior position throughout the activity, and similar medial and lateral condyle motion throughout flexion compared to the CR design. Conclusion. When sacrificing the PCL, MC behaved similar to a contemporary PS design with more medial stability, more lateral laxity in deep flexion, and a posterior position during a lunge activity that did not depend on a cam/spine mechanism. When retaining the PCL, MC behaved similar to a contemporary CR design with more medial stability, similar lateral laxity in deep flexion, and a posterior position during a lunge activity demonstrating that the increased medial conformity did not cause a kinematic conflict with the retained PCL. These findings illustrate the concept that the MC design can be used for both the PCL sacrificing and retaining technique

Total knee arthroplasty using navigation system is known to be more effective than conventional methods in achieving more accurate bone resection and neutral alignment. Mobile bearing is also known to reduce wear and automatically correct rotational mal-alignment of the tibia but the long-term follow-up results of more than 10 years are extremely rare. The purpose of this study is to investigate the results of clinical and radiologic long-term follow-up and complications of total knee arthroplasty using navigation and multi-directional mobile bearing. From 2003 to 2006, a total of 111 navigation TKAs using multi-directional mobile bearing design were carried out and reviewed retrospectively. TKAs were performed by two experienced surgeons at one institute. Of the 111 patients, 102 were women and 9 were men. The mean duration of follow-up was 11.4 ± 1.0 years (range, 10.1 to 14.08 years). Clinical outcomes were evaluated in terms of Knee Society Score, Hospital for Special Surgery score, Western Ontario and McMaster University (WOMAC) score, range of motion and complications. Long-term radiological outcomes and survival rates were evaluated at least 10 years. Average preoperative HSS score was 66.5 ± 9.8 and KSS pain and function score were 25.0 ± 11.8 and 44.5 ± 12.3, respectively. Scores improved to 94.1 ± 8.2, 46.6 ± 11.6 and 88.2 ± 14.6 at the last follow up, respectively. Mean preoperative WOMAC scores of 75.8 ± 16.5 improved to 13.8 ± 16.0 at last follow-up. Five knees required re-operation, two for liner breakage for liner wear, one for distal femoral fracture and one for infection. The estimated 10-year prosthesis survival rates for any reason and for prosthesis-related problems were 95.5% and 97.4%, respectively. TKAs using each techniques resulted in similar good clinical outcomes and post-operative leg alignments. Robotic and navigation TKA appeared to reduce the number of postoperative leg alignment outliers and revision rate compared to conventional TKA

INTRODUCTION

Wear and polyethylene damage have been implicated in up to 22% of revision surgeries after unicompartmental knee replacement. Two major design rationales to reduce this rate involve either geometry and/or material strategies. Geometric options involve highly congruent mobile bearings with large contact areas; or moderately conforming fixed bearings to prevent bearing dislocation and reduce back-side wear, while material changes involve use of highly crosslinked polyethylene. This study was designed to determine if a highly crosslinked fixed-bearing design would increase wear resistance.

INTRODUCTION

The intact, healthy human knee joint is stable under anterior-posterior (AP) loading but allows for substantial internal-external (IE) laxity. In vivo clinical studies of the intact knee consistently demonstrate femoral rollback with flexion (Hill et al., 2000, Dennis et al., 2005). A tri-condylar, posterior stabilized (PS) total knee arthroplasty (TKA) with a rotating platform bearing (TKA-A) has been designed to address these characteristics of the intact knee. The third condyle is designed to guide the femoral component throughout the entire flexion arc (AP stability and femoral rollback with flexion), while the rotating platform bearing allows for IE rotation.

This study used a computer model to compare the AP and IE laxity of a new TKA-A to that of two clinically established TKAs (TKA-B: rotating PS TKA, TKA-C: fixed PS TKA) and to demonstrate improvements in AP stability, IE rotation, and femoral rollback.

Introduction. In an effort to provide a TKA bearing material that balances resistance to wear, mechanical failure and oxidation, manufacturers introduced antioxidant polyethylene. In many designs, this is accomplished through pre-blending the polymer with the antioxidant before consolidation and radiation crosslinking. This study reports the wear performance (in terms of thickness change) of a hindered phenol (PBHP) UHMWPE from analysis of an early series of knee retrievals and explores these questions: 1) What is early-time performance of this new bearing material? 2) Is there a difference in performance between fixed and mobile bearings in this design? 3) How does quantitative surface analysis help understand performance at the insert-tray modular interface?. Methods. A series of 100 consecutive Attune™ knee inserts (DePuy Synthes, Warsaw, IN) received at revision by an IRB approved retrieval laboratory between September 2014 and March 2019 were investigated. In vivo duration was 0–52 months. Both the fixed bearing design (n=74) and the rotating platform mobile bearing design (n=26) were included. Dimensional change was determined by measurement of each insert and compared to the as-manufactured dimensions, provided by the manufacturer. The insert-tray interfaces under the loaded bearing zones were analyzed with light interferometry using an optical surface profiler (NewView™ 7300, Zygo, Middlefield, CT). Statistical analyses to explore relationships between measured variables were conducted using SPSS. Results. Mean total through-thickness change of the inserts was 0.052 mm. Mean rate of thickness change for all inserts having in vivo duration > 12 months was 0.038 mm/year (fixed bearing 0.042, mobile bearing 0.029 mm/year). The rate of thickness change for all inserts showed a decreasing trend with duration that was not statistically significant, (rho -.244, p=.094); however, the mobile bearing cohort alone showed a significant decrease in thickness change rate with duration (rho= −.659; p=.014). Surface roughness (Sa) of the distal surface of the UHMWPE inserts under the bearing areas averaged 1.24 µm (range 0.12 – 8.53) and peak-to-valley height (PV) averaged 27.1 µm (range 4 – 95). Sa and PV both showed a decreasing trend with duration in vivo in the mobile bearing inserts, but that trend did not reach statistical significance (p= 0.05 criterion). Neither Sa nor PV showed correlation with measured thickness change. Discussion. This study indicates that the rate of thickness change of a relatively new antioxidant cross-linked bearing material is very similar to other reported wear rates of crosslinked knee inserts. Lower wear rate of mobile bearing inserts compared to fixed bearings also is consistent with earlier published studies. Direct comparison between quantitative thickness change and objective, quantitative surface metrology on the same series brings new information to the arena of measuring and reporting “wear” of UHMWPE and underscores the importance of the distinction between visual damage and actual thinning of the bearing. The systematic surface analysis of the modular interfaces showing that surface roughness (Sa) and total damage feature topography (PV) trend downward with in vivo duration of mobile bearings supports the hypothesis that relative motion at that interface may ‘polish out’ the surface topography over time. For any figures or tables, please contact authors directly

Introduction. In total knee arthroplasty, the alignment of leg depends on the alignment of the component. In unicompartmental knee arthroplasty, it is determined by the thickness of the implant relative to the bone excised mostly. After initial scepticism, UKA is increasingly accepted as a reliable procedure for unicompartmental knee osteoarthritis with the improvements in implant design, surgical technique and appropriate patient selection. Recently, computer assisted UKA is helpful in accuracy and less invasive procedure. But, fixed bearing or mobile bearing in UKA is still controversy. We compared the early clinical and radiological results of robot-assisted unicompartmental knee arthroplasty using a fixed bearing design versus a mobile type bearing design. Materials and Methods. A data set of 50 cases of isolated compartmental degenerative disease that underwent robot-assisted UKA using a fixed bearing design were compared to a data set of 50 cases using a mobile bearing type design. The operations were performed by one-senior author with the same robot system. The clinical evaluations included the Knee Society Score (knee score, functional score) and postoperative complications. The radiological evaluations was assessed by 3-foot standing radiographs using the technique of Kennedy and White to determine the mechanical axis and femoro-tibial angle for knee alignment. Operative factors were evaluated including length of skin incision, operation time, blood loss, hospital stay and intraoperative complications. Results. There were no statistically significant differences in operation time, skin incision size, blood loss and hospital stay. (p > 0.05) There were no significant differences in Knee Society Scores at last follow up. An average preoperative femorotibial alignment was varus alignment of −1° in both groups. Postoperative patients with fixed-bearing implants had an average +2.1° valgus and the patients with mobile bearing implants had +5.4° valgus in femorotibial alignment, which was different.(p<0.05) There was one case of medial tibia plateau fracture in fixed bearing group in 3 months postoperatively. And there were one case of liner dislocation with unstable knee in 6 weeks postoperatively and one case of femoral component loosening in 1 year postoperatively in mobile bearing group. There was no intraoperative complication. The average preoperative knee score was 45.8, which improved to 89.5 in fixed bearing group and 46.5, which improved to 91.2 in mobile bearing group at last followup. The average preoperative function score was 62.4 which improved to 86.5 in fixed bearing group and 60.7 which improved to 88.2 in mobile bearing group at last followup. Conclusion. In ourearly experience, two types of bearing of robot-assisted UKA groups showed no statistical differences in clinical assessment but there was statistical difference in postoperative radiological corrected alignment. But in aspect of early complications, we think that mobile bearing seems to be requiring more attention in surgery

Introduction. Total-knee-arthroplasty (TKA) is used to restore knee function and is a well-established treatment of osteoarthritis. Along with the widely used fixed bearing TKA design, some surgeons opt to use mobile bearing designs. The mobile-bearing TKA is believed to allow for more freedom in placement of the tibial plate, greater range of motion in internal-external (IE) rotation and greater constraint through the articular surface. This current study evaluates 1) the kinematics of a high constraint three condyle mobile bearing TKA, 2) the insert rotation relative to the tibia, and 3) compares them with the intact knee joint kinematics during laxity tests and activities-of-daily-living (lunge, level walking, stairs down). We hypothesize that 1) in contrast to the intact state the anterior-posterior (AP) stability of the implanted joint increases when increasing compression level while 2) maintaining the IE mobility, and that 3) the high constraint does not prevent differential femorotibial rollback during lunge. Methods. Six fresh-frozen human cadaveric knee joints with a mean donor age of 64.5 (±2.4) years and BMI of 23.3 (±7.3) were tested on a robot (KR140, KUKA) in two different states: 1) intact, 2) after implantation of a three condyle mobile bearing TKA. The tibia plateau and the insert of each tested specimen were equipped with a sensor to measure the insert rotation during testing. Laxity tests were done at extension and under flexion (15°, 30°, 45°, 60° 90°, 120°) by applying subsequent forces in AP and medial-lateral (ML) of ±100N and moments in IE and varus-valgus (VV) rotation (6Nm/4Nm, 12 Nm/-). Testing was performed under low (44N) and weight bearing compression (500N). Loading during the lunge, level walking and stairs descent activity was based on in-vivo data. Resulting data was averaged and compared with the kinematics of the intact knee. Results. Increasing the joint compression resulted in a 90% reduced AP laxity (increased stability) for the implanted case while the intact knee laxity stayed similar. In high compression the implanted IE mobility was reduced by 45% for low and mid flexion angles and by 20% for high flexion angles, while the intact knee IE mobility was reduced by 30% at low and mid flexion and 20% at high flexion. The trend of the rollback behaviour was similar for the implanted and intact joints and showed higher lateral than medial rollback (Figure 3 A). The average insert-rotation was highest during level walking (+ 5° to −2.5°) and lowest during lunge (−3.5° to 2.5° over flexion). Conclusion. The established hypotheses were supported by the above listed results. Increasing the joint compression in the mobile bearing design stabilized the knee in the AP direction and maintained the IE mobility similar to the intact knee. This can be directly related to the design of the TKA articular surface, which has a high impact on constraint as soon as the joint is loaded. However, the high constraint of the TKA did not prevent differential rollback

Introduction. Special high-flexion prosthetic designs show a small increase in postoperative flexion compared to standard designs and some papers show increased anterior knee pain with these prosthesis. However, no randomised controlled trails have been published which investigate difference in postoperative complaints of anterior knee pain. To assess difference in passive and active postoperative flexion and anterior knee pain we performed a randomized clinical trial including the two extremes of knee arthroplasty designs, being a high flex posterior stabilized rotating platform prosthesis versus a traditional cruciate retaining fixed bearing prosthesis. We hypothesised that the HF-PS design would allow more flexion, due to increased femoral rollback with less anterior knee pain than the CR design. We specifically assessed the following hypotheses:. Patients have increased flexion after HF-PS TKA compared to CR TKA, both passive and active. Patients show an increased femoral rollback in the HF-PS TKA as compared to the CR TKA. Patients receiving a HF-PS TKA design report reduced anterior knee pain relative to those receiving the CR TKA. Methods. In total 47 patients were randomly allocated to a standard cruciate retaining fixed bearing design (CR) in 23 patients and to a high-flexion posterior stabilized mobile bearing design (HF-PS) in 24 patients. Preoperative and one year postoperative we investigated active and passive maximal flexion. Furthermore, we used the VAS pain score at rest and during exercise and the Feller score to investigate anterior knee pain. A lateral roentgen photograph was used to measure femoral rollback during maximal flexion. Results. The HF-PS did show a significantly higher passive postoperative flexion; 120.8° (SD 10.3°) vs. 112.0° (SD 9.5°) for the CR group (p=0.004). The active postoperative flexion, VAS-pain score and Feller score did not show significant differences between both groups. Sub analysis with the HF-PS group showed a higher VAS-pain for the patients achieving ≥130° of flexion; 30.5 (SD 32.2) vs. 12.2 (SD 12.5) (p=0.16). The rollback was significantly lower in the CR group compared to the HF-PS group; 4.4 (SD 3.0) vs. 8.4 (SD 2.1). Conclusion. The present study showed a significant higher passive flexion in the Posterior Stabilised-High Flexion mobile bearing compared to a Cruciate Retaining fixed bearing prosthesis. However, this difference disappeared when comparing active flexion. The difference in passive flexion was probably related to a significantly lower rollback causing impingement in the CR prosthesis. No difference in anterior knee pain was found between both groups. However, a suggestion is raised that achieving high-flexion might lead to more patellofemoral complaints/anterior knee pain

There is ongoing debate on the benefits of fixed versus mobile bearing Unicompartmental Knee Replacement (UKR). We report the results from a randomised controlled trial comparing fixed and mobile bearing of the same UKR prosthesis. Forty patients were randomized to receive identical femoral components and either a fixed or mobile bearing tibial component. At 6.5 years follow-up 37% of the mobile bearing design had been revised and 14% for the fixed bearing design. The main reasons for revision were pain and loosening. These results were compared with data from The Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) that show a cumulative percent revision of 24.2% for the mobile bearing Preservation UKR at 6.5 years. All locally explanted mobile bearings were examined microscopically, and 83% demonstrated significant backside wear. Constraint on the undersurface of the bearing coupled with a congruent upper surface may have contributed to the excessive revision rate. This is the first randomised controlled trial examining mobile and fixed variations of the same UKR prosthesis and shows this design of UKR with the mobile bearing has an unacceptably high revision rate and patients with this knee design should be closely monitored

Introduction. The mobile-bearings were introduced in total knee arthroplasty (TKA) to improve the knee performance by simulating more closely ‘normal’ knee kinematics, and to increase the longevity of TKA by reducing the polyethylene wear and periprosthetic osteolysis. However, the superiority between posterior-stabilized mobile-bearing and fixed-bearing designs still remains controversial. The objective of the present study was to compare the mid-term results of Scorpio + Single Axis system (Stryker Howmedica Osteonics, Allendale, New Jersey) for the mobile-bearing knees and Duracon system (Stryker Howmedica Osteonics, Allendale, New Jersey) for the fixed bearing design with regard to clinical and roentgenographic outcome with special reference to any complications and survivorship. Methods. Prospective, randomized, double-blinded controlled study was carried out on 56 patients undergoing primary, unilateral total knee arthroplasty for osteoarthritis, who were divided into two groups. Group I received mobile-bearing knee prosthesis (29 patients) and Group 2 received fixed-bearing prosthesis (27 patients). The patients were assessed by a physical examination and knee scoring systems preoperatively, at a follow-up of three months, six months, and one year after surgery by independent researcher who was not part of the operating team, and was blinded as to the type of implant inserted. We used the Oxford knee score (OKS) and Knee society score (KSS), with Knee Society Knee Score (KSKS) and Knee Society Functional Score (KSFS) being the subsets. The questionnaire for OKS was printed in our national language, and handed over to the patient at each visit. Results. The Knee Society knee scores, pain scores, functional scores and Oxford knee scores were not statistically different (P > 0.05) between the two groups. Mean postoperative range-of-motion of mobile-bearing knees was significantly greater than that of fixed-bearing knees (127º versus 111º, P = 0.011). 72% of patients could sit cross legged, 48% could sit on the floor, and 17% could squat. Kaplan–Meier survival rate was 100%. No spin-out of mobile bearing was observed. The radiological analysis showed no osteolysis or implant loosening. Conclusion. Mobile-bearing, and fixed-bearing knees demonstrated no statistically significant difference in the Oxford knee score, Knee society score, and radiological outcome with 100% survivorship, at 4 to 6.5 years (mean: 5.5 years) follow up. However, the post-operative range-of-motion of mobile-bearing knees was significantly higher than the fixed-bearing designs (mean, 127° versus 111°; range, 95° to 145° versus 80° to 125°)

INTRODUCTION. Aseptic loosening is the most common failure mode for Total Elbow Arthroplasty (TEA) and is considered to be associated with accelerated polyethylene bearing wear [1, 2]. This study aimed to evaluate three commercially available implant designs under loads associated with daily living. The hypothesis was that more recent designs (Discovery and Nexel) provide greater articular contact areas resulting in lower polyethylene stresses compared to the Coonrad/Morrey (CM). METHODS. Motion tracking was performed on a healthy volunteer during elbow flexion at 0, 45, and 90° shoulder abduction because most daily activities occur with some shoulder abduction [3] resulting in varus stress about the elbow. This kinematic data was used in an OpenSim upper extremity musculoskeletal model [4] to estimate muscle and joint reaction loads with 5lb in hand, consistent with the common clinical restrictions following TEA. Computer aided assemblies of the smallest size implants for each system were imported to ANSYS for finite element analysis. Metallic components were treated as rigid and polyethylene components were modeled using a nonlinear elastoplastic constitutive model calibrated to material data. Articular contacts were frictional. Physiologic joint reaction forces and moments quantified in OpenSim were applied and the resulting peak articular contact area and peak bearing von Mises stresses were assessed. RESULTS. Simulated deformation patterns of CM bearings corresponded well to those reported in retrievals studies [1, 2] supporting the clinical relevance of the modeling approach. Peak stresses for CM and Nexel were consistently found in the central and side bearings respectively. The central bearing stresses remained 2–2.6 times lower in Nexel compared to CM. Peak stress for all three TEA systems increased with shoulder abduction (Fig.1, 2). Highest peak stresses (Fig.2) were obtained in CM and consistently exceeded the polyethylene yield limit; CM showed the lowest contact area (Fig.3). Nexel and Discovery experienced peak polyethylene stresses 26–34% and 17–39% lower than CM respectively (Fig.2). DISCUSSION. Our results support the hypothesis that newer TEA systems provide increased articular contact area and reduced bearing stresses during physiological loading. The cylindrical CM central bearing carries both the joint reaction force and moment leading to edge loading and high stresses (Fig.1). The design of the Nexel central bearing provides limited resistance to varus-valgus moment, thus transferring the moment to the side bearings and reducing central bearing stresses. The hemispherical Discovery bearing design was confirmed to offer a large articular contact area. However, non-concentricity of the contact spheres can lead to edge loading and high polyethylene stresses under off-axis forces. CM and Discovery utilize conventional polyethylene, whereas Nexel utilizes highly cross-linked Vitamin-E polyethylene. This study does not account for the increased wear resistance of Vitamin-E as compared to conventional polyethylene [5]. Long term clinical data are needed to demonstrate how these wear properties, as well as the geometric design which has been shown to impact stresses and contact patterns, translate to in vivo performance. For figures, please contact authors directly

Introduction. Complications related to the patellofemoral joint continue to be a substantial source of patient morbidity, causing anterior knee pain, instability, and dysfunction following total knee arthroplasty. One of the principle factors affecting patellofemoral outcomes may be trochlear design. The optimal design is currently unknown. The purpose of the present study was to study patellofemoral joint contact by analysing areas of wear in retrieved femoral components of three modern designs. Materials and Methods. Eighteen retrieved femoral components featuring three different designs (constant radius of rotation, multiple radii of rotation, and multiple radii of rotation with built-in external rotation design) were matched on the basis of time-in-vivo, age, BMI and gender. All implants were cobalt chrome, posterior stabilized, cemented components with fixed bearing design with a resurfaced patella. Trochlear wear and surface damage were assessed using visual inspection, low-magnification light microscopy, and light profilometry. Results. Six implants from each group were successfully matched and were used for the topographical analysis. The femoral components were closely matched on the basis of time-in-vivo (TIV) (2.4 years±1.2), age (71.6 years±11.3), and BMI (33.0 kg/m. 2. ±7.0). There were 9 males and 9 females in the sample. Infection was the most common reason for revision (n=14) followed by instability (n=3) and loosening (n=1). There were no significant differences in TIV, age, and BMI between the groups (p=0.366, p=0.829, and p=0.586, respectively). When compared with unused, reference components, both the retrieved constant radius implants (p<0.05) and multiple radii implants (p<0.05) were significantly rougher than the new components. The retrieved components with multiple radii and built-in external rotation were not substantially rougher than the reference component (p>0.05). Visual inspection of the femoral components showed evidence of damage in all implant types. Modes of damage included scratches, striation, pitting, and delamination. No significant differences between the groups were found with respect to overall damage and wear on visual inspection (p=0.480). However, light profilometry analysis showed significantly increased roughness of multiple radii components compared to constant radius or multiple radii components with built-in external rotation (p<0.05). This was particularly significant in the proximal middle (p=0.045) and medial zones of the trochlea (p=0.017). Conclusions. All retrieved femoral components show evidence of damage in the trochlear area. While retrieved constant radius and multiple radii components showed increased wear compared to new components, retrieved components with multiple radii and built-in external rotation did not differ significantly from their new state. Retrieved multiple radii components appeared to have increased roughness compared with constant radius or multiple radii with built-in external rotation, particularly in the proximal zones of the trochlea. The long term effects of increased trochlear roughness requires further investigation and correlation with clinical outcomes. As the volume and patient demands for total knee arthroplasty increase, a greater understanding of the effect of trochlear design on clinical outcomes is warranted

Aim. The aim of the study was to assess the impact of a self aligning unidirectional mobile tibial bearing and the use of a patella button on lateral patella release rates within a knee system using a common femoral component for both the fixed and mobile variants. Methods and results. A total of 347 patients undergoing TKR were included in the study and randomly allocated to receive either a Mobile Bearing (171 knees) or a Fixed Bearing (176 knees) PS PFC Sigma TKR. Further sub-randomisation into patella resurfacing or retention was performed for both designs. The need for lateral patella release was assessed during surgery using the ‘no thumbs’ technique. The lateral release rate was similar for fixed bearing (9.65%) and mobile bearing (9.94%) implants (p=0.963). Patella resurfacing resulted in lower lateral release rates when compared to patella retention (5.8% vs 13.8%; p=0.0131). This difference was most marked in the mobile bearing group where the lateral release rate was 16.3% with patella retention compared to 3.5% with patella resurfacing (p=0.005). Conclusion. The addition of a rotating platform tibial component had no impact on the lateral release rate in this study. Optimising patella geometry by patella resurfacing appears more important than tibial bearing deisgn per se. The combination of a mobile bearing design and patella resurfacing appears to optimise the lateral release rate and patello-femoral tracking in the PS PFC Sigma design which has a deeply radiused trochlea on the femoral component. The results with a patella resurfacing confirm the results with this prosthesis reported by Pagnano et al in Clin Orthop 428 pp221-227

Background. Previous in vivo fluoroscopic studies have documented that subjects having a PS TKA experience a more posterior condylar contact position at full extension, a high incidence of reverse axial rotation and mid flexion instability. More recently, a PS TKA was designed with a Gradually Reducing Radius (Gradius) curved condylar geometry to offer patients greater mid flexion stability while reducing the incidence of reverse axial rotation and maintaining posterior condylar rollback. Therefore, the objective of this study was to assess the in vivo kinematics for subjects implanted with a Gradius curved condylar geometry to determine if these subjects experience an advantage over previously designed TKA. Methods. In vivo kinematics for 30 clinically successful patients all having a Gradius designed PS fixed bearing TKA with a symmetric tibia were assessed using mobile fluoroscopy. All of the subjects were scored to be clinically successful. In vivo kinematics were determined using a 3D-2D registration during three weight-bearing activities: deep-knee-bend (DKB), gait, and ramp down (RD). Flexion measurements were recorded using a digital goniometer while ground reaction forces were collected using a force plate as well. The subjects then assessed for range of motion, condyle translation and axial rotation and ground reaction forces. Results. During a DKB, subjects implanted a Gradius designed, PS fixed bearing TKA design exhibited an average of 3.35 mm of posterior femoral rollback of the lateral condyle and 2.73 mm of the medial condyle with an average axial rotation of 4.90° in the first 90° of flexion. The average max flexion was 111.4°. From full extension to maximum flexion, the average axial rotation was 4.73°, while the subjects experienced 5.34 and 1.97 mm on the lateral and medial condyle rollback, respectively. During mid flexion from 30 to 60 degrees of flexion, the subjects experienced 1.34° of axial rotation, −1.13 and −0.11 mm of lateral and medial condyle motion. Conclusions. Subjects in this study did experience good weight-bearing flexion and magnitudes of axial rotation and posterior femoral rollback similar to previous PS TKA designs. During mid flexion, subjects in this study did experience less mid flexion paradoxical sliding than other PS TKA, leading to greater mid flexion stability for the patients

Background. Several studies have reported that tibial component in varus alignment can worsen the survivorship of medial unicompartmental knee arthroplasty (UKA). On the other hand, Varus/valgus inclination of the tibial component can affect the location of the contact point between femoral and tibial component especially in round on flat bearing surface design. Along with the tibial component inclination, changes in the contact point may also alter the tibial condylar bone stress, which would affect the longevity or complications after UKA. Method. We constructed a validated three-dimensional finite element model of the tibia with a medial component and assessed stress concentrations by changing the tibial component coronal inclinations (squale inclination, 3° and 6° varus, 3° and 6° valgus inclination). We evaluated the Von Mises stress on the medial tibial metaphyseal cortex and the proximal resected surface when a load of 900N was applied on the tibial component surface by two conditions in each inclination models; one is that the loading site is fixed at the mediolateral center of the tibial component (fixed model), and the other is that the loading site is variable depending on the tibial component inclination (variable model) (Fig.1). Result. In variable models, the loading site moved medially 22.8% of the tibial component width as the tibial component inclination changed from 6°varus to 6°valgus. The Von Mises stress concentrations were observed on the medial tibial metaphyseal cortices and on the anterior and posterior corner of the resected surface in all models (Fig.2). Stress concentration was also observed along the medial cortical rim of the resected surface in valgus tibial component inclination of the fixed model and varus inclination of the variable model (Fig.2). The stress on the medial tibial metaphyseal cortices did not markedly change in any inclination of fixed models, but increased in variable models as the tibial component inclination changed from varus to valgus (Fig.3A). The stress on the medial cortical rim of the resected surface increased with varus inclination in the fixed model and decreased with varus inclination in the variable model (Fig.3B). Changes in the Von Mises stress on the anterior and posterior corner of the resected surfaces did not differ between the fixed and variable model. Discussion. Varus inclination of the tibial component has been considered to increase the bone stress in previous studies. However, in the current study, bone stress on the medial metaphyseal cortex and the medial cortical rim of the resected surface conversely decreased in varus inclination when the change of the femorotibial contact point was taken into consideration. Recent opinion has advocated that restoring the constitutive patient's anatomy by compensating cartilage wear is critical in producing the excellent clinical outcome after UKA. Therefore, three to five degrees of anatomical varus inclination of the tibial component would reduce the tibial condylar bone stress and protective against complications such as unknown postoperative pain or tibial component migration. For figures/tables, please contact authors directly.

INTRODUCTION. Highly cross-linked polyethylene (XLPE) inserts have shown significant improvements in decreasing wear and osteolysis in total hip arthroplasty [1]. In contrast to that, XLPE has not shown to reduce wear or aseptic loosening in total knee arthroplasty [2,3,4]. One major limitation is that current wear testing in vitro is mainly focused on abrasive-adhesive wear due to level walking test conditions and does not reflect “delamination” as an essential clinical failure mode [5,6]. The objective of our study was to use a highly demanding daily activities wear simulation to evaluate the delamination risk of polyethylene materials with and without vitamin E stabilisation. MATERIALS & METHODS. A cruciate retaining fixed bearing TKA design (Columbus® CR) with artificially aged polyethylene knee bearings (irradiation 30 & 50 kGy) blended with and without 0.1% vitamin E was used under medio-lateral load distribution and soft tissue restrain simulation. Daily patient activities measured by Bergmann et al. [7] in vivo, were applied for 5 million knee wear cycles in a combination of 40% stairs up, 40 % stairs down, 10% level walking, 8% chair raising and 2% deep squatting with up to 100° flexion [8] (Fig. 1). The specimens were evaluated for gravimetric wear and analysed for abrasive-adhesive and delamination wear modes. RESULTS. The total amount of gliding surface wear was 28.7±1.9 mg for the vitamin E stabilised polyethylene irradiated with 30 kGy and 26.5±5.7 mg with 50 kGy irradiation, compared to 355.9±119.8 mg for the standard material. The combination of artificial ageing and high demanding knee wear simulation leads to visible signs of delamination in the articulating standard polyethylene bearing areas in vitro. Delamination began after 2 million test cycles for the standard polyethylene, indicated by the transition between linear and exponential slope in Fig. 2. Delamination was not found in the Vitamin E blended gliding surfaces. CONCLUSION. To evaluate moderately or highly cross-linked polyethylenes in regard to ageing and wear behaviour in vitro, conditions are simulated to create clinical relevant failure modes given in total knee arthroplasty. With the applied test protocol it is possible to discriminate between the polyethylene bearing materials with and without Vitamin E stabilisation. To view tables/figures, please contact authors directly

Background. Wear and fatigue damage to polyethylene components remain major factors leading to complications after total knee and unicompartmental arthroplasty. A number of wear simulations have been reported using mechanical test equipment as well as computer models. Computational models of knee wear have generally not replicated experimental wear under diverse conditions. This is partly because of the complexity of quantifying the effect of cross-shear at the articular interface and partly because the results of pin-on-disk experiments cannot be extrapolated to total knee arthroplasty wear. Our premise is that diverse experimental knee wear simulation studies are needed to generate validated computational models. We combined five experimental wear simulation studies to develop and validate a finite-element model that accurately predicted polyethylene wear in high and low crosslinked polyethylene, mobile and fixed bearing, and unicompartmental (UKA) and tricompartmental knee arthroplasty (TKA). Methods. Low crosslinked polyethylene (PE). A finite element analysis (FEA) of two different experimental wear simulations involving TKA components of low crosslinked polyethylene inserts, with two different loading patterns and knee kinematics conducted in an AMTI knee wear simulator: a low intensity and a high intensity. Wear coefficients incorporating contact pressure, sliding distance, and cross-shear were generated by inverse FEA using the experimentally measured volume of wear loss as the target outcome measure. The FE models and wear coefficients were validated by predicting wear in a mobile bearing UKA design. Highly crosslinked polyethylene (XLPE). Two FEA models were constructed involving TKA and UKA XLPE inserts with different loading patterns and knee kinematics conducted in an AMTI knee wear simulator. Wear coefficients were generated by inverse FEA. Results. Predicted wear rates were within 5% of experimental wear rates during validation tests. Unicompartmental mobile bearing back-side wear accounted for 46% of the total wear in the mobile bearing. Wear during the swing phase was 38% to 44% of total wear. Discussion & Conclusions. Crosslinking polyethylene primarily decreased (by nearly 10-fold) the wear generated by cross-shear. This result can be explained by the reduced propensity of crosslinked polyethylene molecules to orient in the dominant direction of sliding. A highly crosslinked fixed-bearing polyethylene insert can provide high wear performance without the increased risk for mobile bearing dislocation. Finite element analysis can be a robust and efficient method for predicting experimental wear. The value of this model is in rapidly conducting screening studies for design development, assessing the effect of varying patient activity, and assessing newer biomaterials. This FEA model was experimentally validated but requires clinical validation