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The Journal of Bone & Joint Surgery British Volume
Vol. 66-B, Issue 5 | Pages 660 - 665
1 Nov 1984
Ogilvie-Harris D Jackson R

Three hundred and nineteen patients who had chondromalacia patellae and persistent patellofemoral pain after six months of conservative management underwent arthroscopy and arthroscopic surgery. The results in four aetiological groups were reviewed at one year and five years after operation. Morbidity was minimal. Lavage produced early remission in all groups. Shaving offered a particular advantage in the post-traumatic group. Lateral release plus shaving and lavage was beneficial in the group with maltracking patellae and in half of the idiopathic group. In the group with unstable patellae, lateral release produced good results in only one in four patients. In conclusion, we consider that arthroscopic surgery has a useful role to play in the management of chondromalacia patellae


The Journal of Bone & Joint Surgery British Volume
Vol. 49-B, Issue 3 | Pages 495 - 501
1 Aug 1967
Crooks LM

1. It is suggested that abruptness of the condylar ridges on the femur plays a major role in the etiology of chondromalacia patellae. The medial condylar ridge is always abrupt in these cases, and indeed in many knees with no evidence of chondromalacia patellae. The lateral condylar ridge is rarely abrupt. 2. The short-term results of forty operations for reduction of femoral ridges in thirty-eight patients, with preservation of the patella in thirty-two cases, are satisfactory


Bone & Joint Research
Vol. 1, Issue 8 | Pages 167 - 173
1 Aug 2012
Jack CM Rajaratnam SS Khan HO Keast-Butler O Butler-Manuel PA Heatley FW

Objectives. To assess the effectiveness of a modified tibial tubercle osteotomy as a treatment for arthroscopically diagnosed chondromalacia patellae. Methods. A total of 47 consecutive patients (51 knees) with arthroscopically proven chondromalacia, who had failed conservative management, underwent a modified Fulkerson tibial tubercle osteotomy. The mean age was 34.4 years (19.6 to 52.2). Pre-operatively, none of the patients exhibited signs of patellar maltracking or instability in association with their anterior knee pain. The minimum follow-up for the study was five years (mean 72.6 months (62 to 118)), with only one patient lost to follow-up. Results. A total of 50 knees were reviewed. At final follow-up, the Kujala knee score improved from 39.2 (12 to 63) pre-operatively to 57.7 (16 to 89) post-operatively (p < 0.001). The visual analogue pain score improved from 7.8 (4 to 10) pre-operatively to 5.0 (0 to 10) post-operatively. Overall patient satisfaction with good or excellent results was 72%. Patients with the lowest pre-operative Kujala score benefitted the most. Older patients benefited less than younger ones. The outcome was independent of the grade of chondromalacia. Six patients required screw removal. There were no major complications. Conclusions. We conclude that this modification of the Fulkerson procedure is a safe and useful operation to treat anterior knee pain in well aligned patellofemoral joints due to chondromalacia patellae in adults, when conservative measures have failed


The Journal of Bone & Joint Surgery British Volume
Vol. 44-B, Issue 3 | Pages 569 - 572
1 Aug 1962
Hodkinson HM

1. The occurrence of bilateral double-layer patellae in association with multiple epiphysial dysplasia is described in three siblings. 2. Twelve cases of bilateral double-layer patellae have been reported previously, and in all there was an accompanying skeletal dystrophy which, although not diagnosed as such, is likely to have been multiple epiphysial dysplasia. 3. It is suggested that although they occur only in a minority of cases, double-layer patellae when present are a feature of considerable diagnostic value in multiple epiphysial dysplasia. Lateral radiography of the knees may therefore be of assistance in the diagnosis of multiple epiphysial dysplasia


The Journal of Bone & Joint Surgery British Volume
Vol. 67-B, Issue 5 | Pages 769 - 774
1 Nov 1985
Bentley G

Full thickness samples of articular cartilage were removed from areas of chondromalacia on the medial and "odd" facets of the patellae of 21 adults and examined by histology, autoradiography and electron microscopy. Surface fibrillation, loss of superficial matrix staining and reduced 35SO4 labelling was seen, with little change in the deep zone. Ten cases showed "fibrous metaplasia" of the superficial cartilage with definite evidence of cell division and apparent smoothing of the surface. Scattered chondrocyte replication appeared to occur in the surrounding intact cartilage. The findings suggest that early lesions in chondromalacia patellae may heal either by cartilage or fibrous metaplasia and that this may account for the resolution of clinical symptoms


The Journal of Bone & Joint Surgery British Volume
Vol. 59-B, Issue 1 | Pages 58 - 63
1 Feb 1977
Edwards D Bentley G

Six cases of osteochondritis dissecans patellae have been studied in five patients in an attempt to clarify the aetiology and prognosis. Assessment of the results of treatment was performed using a standard protocol. The thirty-four previous case reports in the literature are reviewed. In four of the five patients symptoms began after flexing the knee under load and three showed patellar subluxation on tangential radiographs. Thus, repetitive shearing stress on the patellar surface is thought to be an important aetiological factor. The indication for operation is a loose osteochondral fragment either wholly or partly detached from the articular surface of the patella. Vertical excision of the affected area of articular cartilage with drilling of the underlying bone gave two "good" and two "excellent" results. Healing of the drilled area and maintenance of the cartilage space was seen in radiographs of all four cases so treated. This simple method of treatment, which probably causes filling of the defect in the surface by fibrocartilage, is recommended


The Journal of Bone & Joint Surgery British Volume
Vol. 60-B, Issue 1 | Pages 74 - 81
1 Feb 1978
Bentley G

Four methods of surgical treatment of chondromalacia patellae have been evaluated after periods ranging from two to thirty years (average seven years), to discover the success rate, complications and indications for each. A total of 140 operations had been performed in 98 patients. Overall, satisfactory results were achieved in 25 per cent after forty shavings of the patellar cartilage, 35 per cent after twenty cartilage excisions and drilling of the subchondral bone, 60 per cent after twenty medial transfers of the patellar tendon and 77 per cent after sixty patellectomies. Thirty-four primary patellectomies gave 82 per cent satisfactory results compared with 62 per cent after twenty-six patellectomies performed after a previously unsuccessful operation. The results were worst in patients below twenty years of age especially women and in those with Grade IV changes in the patellar cartilage. Weakness of the quadriceps after any procedure predisposed to an unsatisfactory result. Extensive late radiological degenerative changes in the knee were not seen. On the basis of the results in this report, patellar tendon transfer is recommended in adolescents and athletes with Grade I, II or III changes in the patellar cartilage. In adults over twenty years of age with Grade I and II changes cartilage excision and drilling is satisfactory. In adults with Grade III and adults or adolescents with Grade IV changes patellectomy is the treatment of choice


The Journal of Bone & Joint Surgery British Volume
Vol. 46-B, Issue 2 | Pages 179 - 190
1 May 1964
Outerbridge RE

1 . Current theories of the etiology of chondromalacia patellae do not explain satisfactorily either its great frequency or its common site of origin on the medial patellar facet. 2. The etiology can be more logically explained by the presence of a ridge on the upper anterior border of the cartilage of the medial femoral condyle, in most knees. This ridge, consisting of cartilage, or cartilage and bone, varies considerably in height and, in normal knee joint movement, causes considerable friction on the medial patellar facet. 3. The degenerative changes were found to be greater in the presence of the larger ridges, and–because of longer wear and tear–in the older patients. 4. This study indicates that chondromalacia was more severe in women than in men, and in patients overweight. Although the activity of the individual and the power of the quadriceps mechanism must play an extremely important part in this condition, it was not possible to assess this. 5. Two factors previously considered to be important in the etiology of this condition, namely, the length of the patellar tendon and Wiberg's Type III patellar shape, have not been confirmed in this study. 6. Resulting from the present investigation certain precautions are suggested in rehabilitation after operations on the knee, and a surgical method for discouraging the progress of this common, and sometimes disabling, condition has been devised


The Journal of Bone & Joint Surgery British Volume
Vol. 68-B, Issue 2 | Pages 297 - 300
1 Mar 1986
Dowd G Bentley G

Minor degrees of malalignment of the patella and anatomical abnormalities including a flattened sulcus angle and an increased ratio between patellar tendon length and patellar length (PT:P) have been suggested as predisposing factors in the causation of chondromalacia patellae, as well as patellar instability. In order to confirm or refute this hypothesis a prospective study has been performed comparing the congruence and sulcus angles and the PT:P ratio in a group of 35 patients with chondromalacia confirmed by arthroscopy and a group of 33 patients with instability, with those of a group of 50 knees in normal volunteers. While there was a statistically significant correlation between an increased sulcus and congruence angle and a high-riding patella in patients with instability, no correlation could be identified in patients with idiopathic chondromalacia


The Journal of Bone & Joint Surgery British Volume
Vol. 61-B, Issue 4 | Pages 435 - 442
1 Nov 1979
Sikorski J Peters J Watt I

A new radiological technique is presented in which serial axial radiographs of the patellofemoral joints are taken under conditions in which the muscles about the knee and hip are contracted in a manner similar to that during weight-bearing. A form of analysis has been developed whereby patellar rotation can be measured in two planes and femoral rotation about its long axis inferred. A population of asymptomatic adults and children was investigated in this way and their results (regarded as normal) compared with those in fifteen children with idiopathic chondromalacia patellae. In the normal child the femur rotates medially with the onset of muscle activity; by contrast the children with chondromalacia show a reversal of this mechanism


The Bone & Joint Journal
Vol. 105-B, Issue 6 | Pages 622 - 634
1 Jun 2023
Simpson CJRW Wright E Ng N Yap NJ Ndou S Scott CEH Clement ND

Aims

This systematic review and meta-analysis aimed to compare the influence of patellar resurfacing following cruciate-retaining (CR) and posterior-stabilized (PS) total knee arthroplasty (TKA) on the incidence of anterior knee pain, knee-specific patient-reported outcome measures, complication rates, and reoperation rates.

Methods

A systematic review of MEDLINE, PubMed, and Google Scholar was performed to identify randomized controlled trials (RCTs) according to search criteria. Search terms used included: arthroplasty, replacement, knee (Mesh), TKA, prosthesis, patella, patellar resurfacing, and patellar retaining. RCTs that compared patellar resurfacing versus unresurfaced in primary TKA were included for further analysis. Studies were evaluated using the Scottish Intercollegiate Guidelines Network assessment tool for quality and minimization of bias. Data were synthesized and meta-analysis performed.


The Bone & Joint Journal
Vol. 105-B, Issue 12 | Pages 1279 - 1285
1 Dec 2023
Baker JF Nadar AC Jouflas AC Smith LS Sachdeva S Yakkanti MR Malkani AL

Aims

The use of cementless total knee arthroplasty (TKA) components has increased during the past decade. The initial design of cementless metal-backed patellar components had shown high failure rates due to many factors. The aim of this study was to evaluate the clinical results of a second-generation cementless, metal-backed patellar component of a modern design.

Methods

This was a retrospective review of 707 primary TKAs in 590 patients from a single institution, using a cementless, metal-backed patellar component with a mean follow-up of 6.9 years (2 to 12). A total of 409 TKAs were performed in 338 females and 298 TKAs in 252 males. The mean age of the patients was 63 years (34 to 87) and their mean BMI was 34.3 kg/m2 (18.8 to 64.5). The patients were chosen to undergo a cementless procedure based on age and preoperative radiological and intraoperative bone quality. Outcome was assessed using the Knee Society knee and function scores and range of motion (ROM), complications, and revisions.


The Bone & Joint Journal
Vol. 105-B, Issue 12 | Pages 1235 - 1238
1 Dec 2023
Kader DF Jones S Haddad FS


The Journal of Bone & Joint Surgery British Volume
Vol. 43-B, Issue 4 | Pages 752 - 757
1 Nov 1961
Outerbridge RE

1. Chondromalacia of the patella starts most frequently on the medial facet.

2. The anatomy of the medial femoral condyle is described, including the rim at its superior border, and the different arrangement at the upper border of the lateral femoral condyle.

3. Rubbing of the medial patellar facet on the rim at the upper border of the medial femoral condyle can explain in part the etiology of chondromalacia.


The Journal of Bone & Joint Surgery British Volume
Vol. 64-B, Issue 2 | Pages 202 - 205
1 Apr 1982
Osborne A Fulford P


The Journal of Bone & Joint Surgery British Volume
Vol. 60-B, Issue 2 | Pages 205 - 210
1 May 1978
Abernethy P Townsend P Rose R Radin E

The articular cartilage of the patella was studied in 100 knees at necropsy. In twenty-one of these knees the cartilage changes were related to the trabecular architecture of the underlying bone. It would appear that the initiation and location of cartilage damage and its rate and degree of progression are related to the relative stiffness of the underlying cancellous bone. On the basis of our observations we suggest that the diagnosis "chondromalacia of the patella" should be reserved for patients with asymptomatic or transiently symptomatic fibrillation of the articular cartilage of the central medial patellar facet. Those patients with persistent patellofemoral pain should be considered to have some other syndrome.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 158 - 158
1 Mar 2008
Boldt DJ Keblish P Munzinger U
Full Access

The purpose of this prospective and randomized study was to objectively evaluate isokinetic strength, clinical, and radiographical outcome in bilateral TKA using the same prosthesis with and without patella resurfacing.

Bilateral TKA, one with, one without patella resurfacing was performed in 22 osteoarthritic patients, mean age was 68 years using the Low-Contact-Stress prosthesis. Minimum Follow-up was one year. Evaluation included clinical investigation, specific patella scores, radiographic analysis and isokinetic strength measurement of both knee flexion and extension at 60 degrees per second (Biodex). surement at 60 degrees per second (Biodex).

There was no significant clinical score difference, but mean isokinetic strength of knee extension was significantly (p< .0001) stronger in the non-resurfaced patella TKA (40.5 Nm) compared with the resurfaced TKA (38,5 Nm). Flexion was also significantly stronger in the patella non-resurfaced group with 22.4 Nm versus 19.5 Nm in the resurfaced group. Mean lateral deviation was significantly (p< .001) less ideal in the resurfaced group as was postoperative patellofemoral congruent contact (p< .001). However, there was no correlation between lateral patella deviation or congruent contact and iso-kinetic strength.

The results of this study indicate that mean isokinetic strength of both knee flexion and extension was significantly stronger in the non-resurfaced patella TKA. This study provides encouraging data for patella non-resurfacing. However, clinical scores or patient’s preference did not show any difference.


The Journal of Bone & Joint Surgery British Volume
Vol. 58-B, Issue 3 | Pages 291 - 299
1 Aug 1976
Goodfellow J Hungerford D Woods C

Two distinct lesions affect the articular cartilage of the patella. Surface degeneration occurs particularly on the odd facet; it is age dependent, often present in youth and it becomes more frequent with increasing age. It probably does not occasion patello-femoral pain in youth, but may predispose to degenerative arthritis in that joint in later years and is regarded as a consequence of habitual disuse. The term "basal degeneration" is used to describe a lesion in which there is a fasciculation of collagen in the middle and deep zones of cartilage without, at first, affecting the surface. It was found astride the ridge separating the medial from the odd facet in twenty-three adolescents who had complained of prolonged patello-femoral pain. They were treated by excision of the disc of affected cartilage, with relief of pain in most cases. The pathogenesis of basal degeneration is related to the functional anatomy of the patella.


The Journal of Bone & Joint Surgery British Volume
Vol. 77-B, Issue 5 | Pages 832 - 833
1 Sep 1995
Sandhu P Broughton N Menelaus M


Full Access

Lateralisation of the tuberosity tibia causes distal malalignment of the extensor mechanism of the knee and can lead to lateral tracking patella (LTP), resulting in anterior knee pain, or objective patellar instability (OPI), resulting in recurrent luxations. For a precise preoperative diagnosis the tuberositas tibia (TT) trochlear groove (TG) distance was measured on a CT scan. A distance of more than 15 mm was considered to be pathological.

In a prospective study, the clinical results of a subtle, CT-guided medial tuberosity transfer for LTP and OPI were evaluated. 30 Consecutive patients with LTP and 30 patients with OPI and an increased TT TG were included. Outcomes were documented at 3, 12 and 24 months follow-up using the Lysholm scale, the Kujala score, and a visual analogue pain score. Postoperatively all but one patient reported good improvement in stability (no persistent subluxations or luxations). All patients had a marked improvement in pain and functional scores at follow up. Complications seem to be related to the peroperative technique. CT-guided TT transfer appears to be satisfactory and safe method for treating patients with an increased TT TG leading to either LTP or OPI.


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_16 | Pages 31 - 31
17 Nov 2023
Warren J Cowie R Jennings L Wilcox R Fermor H
Full Access

Abstract. Objectives. The aim of this study was to develop an in vitro GAG-depleted patella model and assess the biomechanical effects following treatment with a SAP:CS self-assembling hydrogel. Methods. Porcine patellae (4–6 month old) were harvested and subject to 0.1% (w/v) sodium dodecyl sulfate (SDS) washes to remove GAGs from the cartilage. Patellae were GAG depleted and then treated by injection with SAP (∼ 6 mM) and CS (10 mg) in Ringer's solution through a 30G needle. Native, GAG depleted and SAP:CS treated patellae were tested through static indentation testing, using 15g load, 5mm indenter over 1hr period. The degree of deformation of each group was assessed and compared (Mann-Whitney, p<0.05). Native, GAG depleted, sham (saline only) and SAP:CS treated paired patellae and femurs were additionally characterized tribologically through sequential wear testing when undergoing a walking gait profile (n=6 per group). The cartilage surfaces were assessed and compared (Mann-Whitney, p<0.05) using the ICRS scoring system, surface damage was illustrated through the application of Indian ink. Results. Static indentation tests indicated significant increase in indentation deformation of GAG depleted group compared to native group (n=6, p<0.01) and significant reduction in deformation of SAP:CS treated group compared to GAG depleted group (n=6, p<0.05). Sequential wear tests indicated a significant increase in the cartilage damage on the both surfaces of the patellofemoral joint in the GAG depleted group, compared to the native group (n=6, p<0.001), Following SAP:CS treatment, significant protection from damage was observed on femoral surface (n=6, p<0.005), with some non-significant reduction in damage on the patella surface. Sham injections showed no significant increase in damage compared to the native and treated samples. Conclusions. The ∼50% reduction of GAGs represented a moderate osteoarthritic patella cartilage model. This same loss transferred to the dynamic wear tests with significant changes in the damage on the femoral counter face associated with the GAG loss. SAP:CS treatment showed promise in restoring cartilage stiffness to treat Chondromalacia patella in static indentation tests. Sequential wear tests showed that the SAP:CS treatment protects the cartilage layer of both surfaces in the patellofemoral joint from damage in an extreme degeneration model. The sham injections showed that injecting cartilage with a 30G and saline does not cause any significant damage to the cartilage layer. Declaration of Interest. (a) fully declare any financial or other potential conflict of interest


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 63 - 63
1 Feb 2020
Darwish O Langhorn J Van Citters D Metcalfe A
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Introduction. Patella implant research is often overlooked despite its importance as the third compartment in a total knee replacement. Wear and fracture of resurfaced patellae can lead to implant failure and revision surgeries. New simulation techniques have been developed to analyze the performance of patella designs as they interact with the trochlear groove in total knee components, and clinical validation is sought to ensure that these simulations are appropriate. The objective of this work was to subject several patellar designs to patient-derived deep knee bend (DKB) inputs on a 6 degree of freedom (DOF) simulator and compare the resultant wear scars to clinical retrievals. Materials and Methods. Previously reported DKB profiles were developed based on in vivo patellofemoral data and include a wide range of patient variability. The profiles chosen for this body of work were based on the stress in the patellar lateral facet; maximizing this stress whilst maintaining the ability to run the profile stably on the simulator. Load/kinematic profiles were run on three patellar designs (n=3 per group) for 220,000 cycles at 0.8Hz on an AMTI VIVO joint simulator. A comparison cohort of clinically retrieved devices of the same design was identified in an IRB-approved database. Exclusion criteria included gross delamination, cracking secondary to oxidation, and surgeon-reported evidence of malalignment leading to mal-tracking. 29 Patellae were included for analysis: PFC. ®. All Poly (n=14), ATTUNE. ®. Anatomic (n=6), and ATTUNE. ®. Medialized Dome (n=9). Mean in vivo duration was 70.1 months. Patellae were analyzed under optical microscope in large-depth-of-field mode to map the surface damage profile. Burnishing ‘heat-maps’ were generated for retrievals and simulated patellae by normalizing the patellar size and overlaying silhouettes from each component of the same type using a custom-developed MatLAB code. Results. Burnishing heat-map comparisons between retrievals and simulator specimens for each of the three designs were compared. Retrievals show more variation than simulator devices, however the general loci and relative area of burnished regions is closely aligned for each of the three designs. The retrieved and simulated burnishing scar heat-maps on all-poly PFC. ®. patellae are centered medio-laterally with a wider profile on the lateral aspect. The burnishing marks are continuous. A similar observation may be made of the ATTUNE. ®. medialized dome, retrievals and simulator specimens, though the contact areas appear to be more concentrated away from the apex. The anatomic patellae show two primary regions of contact, and minimal burnishing at the apex. The simulator specimens likewise show two principal regions of contact. Discussion. Wear scar analysis shows that joint simulation on AMTI VIVO yields clinically relevant wear patterns across a variety of device types. Clinically relevant damage provides insight that load and motion inputs to the simulator deliver results that may be used to interpret in vivo performance or analyze future designs and/or materials. This qualitative surface contact analysis will help to inform future quantitative mass loss and fatigue failure studies. For any figures or tables, please contact authors directly


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_16 | Pages 47 - 47
1 Dec 2021
Kayode O Day G Wijayathunga N Mengoni M Wilcox R
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Abstract. Introduction. Osteoarthritis (OA) is one of the lead causes of pain and disability in adults. Bone marrow lesions (BMLs) are one feature of subchondral bone involvement in OA. MRI images suggest changes in tissue content and properties in the affected regions however, it is not known if this alters the mechanical behavior of the bone, which could in turn affect OA progression. The aim of this study was to characterize the mechanical properties of BMLs, using a combined experimental and computational approach. Methods. Six human cadaveric patellae from donors aged 56–76 were used in this study; all exhibited BML regions under MRI. Bone plugs were taken from non-BML (n = 6) and BML (n = 7) regions within the patellae, with guidance from the MRI. The plugs were imaged at 82µm resolution using micro computed tomography (µCT) and tested under uniaxial compression. Finite element (FE) models were created for each plug from the µCT scans and morphological properties such as bone volume fraction (BV/TV) were also determined. The relationship between bone volume fraction and apparent modulus was investigated for both sample groups. Results. The BV/TV range was similar for the BML and non-BML groups (0.25–0.46 and 0.18–0.44) From the experimental tests, a moderate positive correlation was found between BV/TV and apparent modulus in the no BML group (r= 0.57) while no correlation was found in the BML group (r = −0.02). From the FE results, a different relationship between BV/TV and element elastic modulus was found for the BML and non-BML groups. Conclusions. The results of this study show that in regions of bone containing BMLs, bone volume fraction does not predict overall apparent modulus and has different relationship to local modulus, suggesting the BML associated tissue structural changes affect mechanical behavior. Funders: EPSRC


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_4 | Pages 28 - 28
1 Mar 2021
Amado I Mathavan N Cavanagh B Murphy C Kennedy O
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Osteoarthritis (OA) is a disease that affects both bone and cartilage. Typically, this disease leads to cartilage degradation and subchondral bone sclerosis but the link between the two is unknown. Also, while OA was traditionally thought of as non-inflammatory condition, it now seems that low levels of inflammation may be involved in the link between these responses. This is particularly relevant in the case of Post-Traumatic OA (PTOA), where an initial phase of synovial inflammation occurs after injury. The inflammatory mediator interleukin 1 beta (IL-1B) is central to this response and contributes to cartilage degradation. However, whether there is a secondary effect of this mediator on subchondral bone, via bone-cartilage crosstalk, is not known. To address this question, we developed a novel patellar explant model, to study bone cartilage crosstalk which may be more suitable than commonly used femoral head explants. The specific aim of this study was to validate this novel patellar explant model by using IL-1B to stimulate the inflammatory response after joint injury and the subsequent development of PTOA. Female Sprague Dawley rats (n=48) were used to obtain patellar explants, under an institutional ethical approval license. Patellae were maintained in high glucose media, under sterile culture conditions, with or without IL-1B (10ng/ml), for 7 days. Contralateral patellae served as controls. One group (n= 12) of patellae were assessed for active metabolism, using two both Live and Dead (L/D) staining and an Alamar Blue assay (AB). A second group (n=12) was used for tissue specific biochemical assays for both bone (Alkaline Phosphatase) and cartilage (sulfated proteoglycan and glycosaminoglycan (sGaG)). Finally, a third group (n=28) of explants were used for histologically analysis. Samples were decalcified, embedded in paraffin and sectioned to 7µm thickness, and then stained using H&E; and Safranin O with fast green. Additionally, toluidine blue and alkaline phosphatase staining were also performed. Our results demonstrate that our system can maintain good explant viability for at least 7 days, but that IL-1B reduces cell viability in patellar cartilage, as measured by both L/D and AB assays after 0, 2, 4 and 7 days in culture. In contrast, sGaG content in cartilage were increased by this treatment. Additionally, ALP, a marker of osteoblastic activity, was increased in IL-1B treated group 4 and 7 days, but was also showed some increase in control groups. Histological analyses showed that IL-1B treatment resulted in reduced proteoglycan staining, demonstrating the powerful effect of this factor in injury response over time. Thus, we conclude that IL-1B affects both bone and cartilage tissues independently in this system, which may have relevance in understanding bone-cartilage crosstalk after injury and how this is involved in PTOA development


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_6 | Pages 7 - 7
1 Apr 2018
Cowie R Briscoe A Fisher J Jennings L
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Introduction. Experimental wear simulation of an all-polymer knee implant has shown an equivalent rate of wear of UHMWPE tibial components against PEEK-OPTIMA™ and cobalt chrome femoral components of a similar initial geometry and surface topography. However, when the patella is resurfaced with an UHMWPE patella button, it is important to also ascertain the wear of the patella. Wear debris from the patella contributes to the total volume of wear debris produced by the implant which should be minimised to reduce the potential for osteolysis and subsequent implant loosening. The aim of this study was to investigate the wear of the patellofemoral joint in an all-polymer knee implant. The wear of UHMWPE patellae articulating against PEEK-OPTIMA™ femoral components was compared to UHMWPE articulating against cobalt chrome femoral components. Materials and Methods. Six mid-size (size C) PEEK-OPTIMA™ femoral components (Invibio Knee Ltd., UK) and six cobalt chrome femoral components of similar initial surface topography and geometry were coupled with 28mm all-polyethylene GUR1020 patellae (conventional, EO sterile) (Maxx Orthopaedics, USA). The implants were set up in a ProSim 6 station electromechanical knee simulator (Simulation Solutions, UK) which was modified for testing the patellofemoral joint. 3 million cycles (MC) of wear simulation was carried out under kinematics aiming to replicate a gait cycle adapted for an electromechanical simulator from previous work by Maiti et al. The simulator used has six degrees of freedom of which four were controlled; axial force up to 1200N, flexion/extension 22°, superior-inferior (SI) displacement (22mm) and Abduction-adduction (AA) (4°). The SI and AA were displacement controlled and driven through the patella. The medial-lateral displacement and tilt (internal/external rotation) of the patella were passive so the patella button was free to track the trochlear groove. The lubricant used was 25% bovine serum supplemented with 0.03% sodium azide to retard bacterial growth. The wear of patellae was determined gravimetrically with unloaded soak controls used to compensate for the uptake of moisture by the UHMWPE. The mean wear rate ± 95% confidence limits were calculated and statistical analysis was carried out using ANOVA with significance taken at p<0.05. Results. The mean wear rates of the UHMWPE patellae were 0.26±0.21 mm. 3. /MC and 0.35±0.17 mm. 3. /MC against PEEK-OPTIMA™ and cobalt chrome femoral components respectively. There was no significant difference in wear rate against the different femoral component materials (P=0.38). Against both femoral component materials, a ‘bow tie’ shaped wear scar was evident on the patellae typical of that seen in retrieval studies and reported in previous experimental wear simulation of the patellofemoral joint. Conclusion. The wear rate of the UHMWPE patellae was low against both PEEK-OPTIMA™ and cobalt chrome femoral components and comparable to previous work by Vanbiervliet et al. This study further shows that in terms of its wear performance, PEEK-OPTIMA™ has promise as an alternative bearing material to cobalt chrome in the femoral component of total knee replacements


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_2 | Pages 78 - 78
1 Mar 2021
Kandhari V Grasso S Twiggs J
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Abstract. Background. Accurate analysis of the patellar resurfacing is essential to better understand the etiology of patella-femoral problems and dissatisfaction following total knee arthroplasty (TKA). In the current published literature patellar resurfacing is analysed using 2D radiographs. With use of radiographs there is potential for error due to differences in limb positioning, projection, anatomic variability and difficulties in appreciating the cement-bone interface. So, we have developed a CT Scan based 3D modelled technique for accurate evaluation of patellar resurfacing. Methods. This technique for analyses of patellar resurfacing is based on the pre-operative and pos-operative CT Scan data of the patients who underwent TKA with patellar resurfacing. In the first step, accurately landmarked 3D models of pre-op patellae were created from pre-operative CT Scan data in ScanIP software. This model was imported in Geomagic design software and computational model of post-op patella was created. This was further analysed to determine the inclination of the patellar resection plane, patellar button positioning and articular volumetric restoration of the patella. Reliability and reproducibility of the technique was tested by comparing 3 sets of 10 measurements done by 2 independent investigators on 30 computational models of patellae derived from the data of randomly chosen 30 TKA patients. Results. The developed technique for analyses of patellar resurfacing is reliable and reproducible. The intraclass correlation co-efficient was >0.90 for the 10 measurements performed by two investigators. Conclusions. This technique can be used by surgeons and engineers for accurate analysis of the patellar resurfacing especially in patients with persistent patello-femoral problems after TKA. Declaration of Interest. (a) fully declare any financial or other potential conflict of interest


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_13 | Pages 26 - 26
1 Nov 2021
Amado I Hodgkinson T Murphy C Kennedy O
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Introduction and Objective. Traditionally, osteoarthritis (OA) has been associated mostly with degradation of cartilage only. More recently, it has been established that other joint tissues, in particular bone, are also centrally involved. However, the link between these two tissues remains unclear. This relationship is particularly evident in post-traumatic OA (PTOA), where bone marrow lesions (BMLs), as well as fluctuating levels of inflammation, are present long before cartilage degradation begins. The process of bone-cartilage crosstalk has been challenging to study due to its multi-tissue complexity. Thus, the use of explant model systems have been crucial in advancing our knowledge. Thus, we developed a novel patellar explant model, to study bone cartilage crosstalk, in particular related to subchondral bone damage, as an alternative to traditional femoral head explants or cylindrical core specimens. The commonly used osteochondral explant models are limited, for our application, since they involve bone damage during harvest. The specifics aim of this study was to validate this novel patellar explant model by using IL-1B to stimulate the inflammatory response and mechanical stimulation to determine the subsequent developments of PTOA. Materials and Methods. Lewis rats (n=48) were used to obtain patellar and femoral head explants which were harvested under an institutional ethical approval license. Explants were maintained in high glucose media (containing supplements), under sterile culture conditions. Initially, we characterised undamaged patellar explants and compared them with the commonly used femoral head. First, tissue viability was assessed using an assay of metabolic activity and cell damage. Second, we created chemical and mechanical damage in the form of IL-1B treatment, and mechanical stimulation, to replicate damage. Standard biochemical assays, histological assays and microstructural assays were used to evaluate responses. For chemical damage, explants were exposed to 10ng/ml of IL-1B for 24 hours at 0, 1, 3 and 7 days after harvesting. For mechanical damage, tissues were exposed to mechanical compression at 0.5 Hz, 10 % strain for 10 cycles, for 7 days. Contralateral patellae served as controls. In both groups, sGAG, ADAMTS4, and MMP-13 were measured as an assessment of representative cartilage responses while ALP, TRAP and CTSK were assessed as a representative of bone responses. In addition to this, histomorphometric, and immunohistochemical, evaluations of each explant system were also carried out. Results. Our results confirm that the patellar explant system is an excellent ex vivo model system to study bone-cartilage crosstalk, and one which does not induce any bone damage at the time of tissue harvest. We successfully established culture conditions to maintain viability in these explants for up to 28 days. Rat IL-1B treatment resulted in increased both proteoglycan content and bone metabolism markers after 7 days when compared with the controls. To confirm this finding, qualitative immunohistochemical staining showed chondrocytes increased expression of MMP13 after treatment with IL-1B. Furthermore, we observed that the levels of ADAMTS4 decreased in 48 hours after IL-1B exposure. Contrastingly IL-1B treatment had the opposite effect on CTSK markers when compared with the control. Mechanically compressed patellae showed a decrease in compressive moduli from day 3 to day 7, suggesting that tissue remodelling may have taken place as a compensatory mechanism in response to damage. In addition, MMP13 release decreased over 48 hours after mechanical compression, while TRAP levels were increased compared with the control. Conclusions. Thus, we successfully demonstrated that IL-1B and mechanical stimulation affects both bone and cartilage tissues independently in this system, which may have relevance in the understanding of bone-cartilage crosstalk after injury and how this is involved in PTOA development


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_8 | Pages 29 - 29
1 May 2016
Harris S Iranpour F Riyat H Cobb J
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Introduction. The trochlea of a typical patellofemoral replacement or anterior flange of a total knee replacement usually extends past the natural trochlea and continues onto the femoral anterior cortex. One reason for this is that it allows a simple patella button to be permanently engaged in the trochlea groove in an attempt to ensure stability. On the natural patella, the apex helps to guide it into the trochlea groove as the knee moves from full extension into flexion. The aim is to study whether a generalised patella can be created that is close in form to a healthy patella. Method. MRI scans were taken of 30 patellae. Characteristics of these patellae (height, width, thickness, apex angle) were measured. The apex angle was found to be similar between patellae (mean=126 degrees, sd = 8.8), as were the ratios between height and width (mean width/height = 1.05, sd = 0.07) and between thickness and width (mean width/thickness = 1.8, sd = 0.19). These patellae were then segmented to create a surface including cartilage, resulting in 30 STL (stereolithography) files in which the surfaces are represented by triangle meshes. To design the average patella the individual patellae were aligned to a standard frame of reference by placing a set of landmarks on the proximal/distal, medial/lateral and anterior/posterior extents of each (fig.1). The vertical axis was defined as passing parallel to the proximal/distal points and the horizontal as passing parallel to the medial/lateral points when looking along the computed vertical axis. The origin centre of the frame of reference was chosen to be mid-way between these points. The mean width was then computed and each patella scaled linearly around the origin to give them all equal width. All the aligned patellae were then averaged together to provide a composite cartilaginous patella. The averaging process was achieved by taking one patella as a seed. The patella chosen for seed was that whose parameters were closest to the average width, height and thickness. An approximately normal vector was passed a point ‘P’ on the seeds, and the points at which these intersected the other models were then determined. The closest intersection point to ‘P’ on each model was chosen and these averaged together. ‘P’ is then replaced in the model with this average point. The averaging process then continues with all the remaining points on the seed model in the same manner to build the average models. Results and Discussion. The mean patella was compared with individual patellae. This comparison was performed by taking each point on the mean patella and finding the closest point on individual patellae - a colour coded map of differences was obtained (fig.2) along with a mean of the absolute difference for each patella. The absolute mean difference ranged from 0.56mm to 1.33mm, averaging at 0.85mm. This shows a reasonable fit between the average patella and each individual example, raising the possibility of using the average shape in future research to develop anatomical patellofemoral replacements and for planning patella resurfacing


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_3 | Pages 18 - 18
23 Feb 2023
Grant M Zeng N Lin M Farrington W Walker M Bayan A Elliot R Van Rooyen R Sharp R Young S
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Joint registries suggest a downward trend in the use of uncemented Total Knee Replacements (TKR) since 2003, largely related to reports of early failures of uncemented tibial and patella components. Advancements in uncemented design such as trabecular metal may improve outcomes, but there is a scarcity of high-quality data from randomised trials. 319 patients <75 years of age were randomised to either cemented or uncemented TKR implanted using computer navigation. Patellae were resurfaced in all patients. Patient outcome scores, re-operations and radiographic analysis of radiolucent lines were compared. Two year follow up was available for 287 patients (144 cemented vs 143 uncemented). There was no difference in operative time between groups, 73.7 v 71.1 mins (p= 0.08). There were no statistical differences in outcome scores at 2 years, Oxford knee score 42.5 vs 41.8 (p=0.35), International Knee Society 84.6 vs 84.0 (p=0.76), Forgotten Joint Score 66.7 vs 66.4 (p=0.91). There were two revisions, both for infection one in each group (0.33%). 13 cemented and 8 uncemented knees underwent re-operation, the majority of these being manipulation under anaesthetic (85.7%), with no difference (8.3% vs 5.3%, 95% CI -2.81% to 8.89%, p = 0.31). No difference was found in radiographic analysis at 2 years, 1 lucent line was seen in the cemented group and 3 in the uncemented group (0.67% v 2.09%, 95%CI -4.1% to 1.24%, p = 0.29). We found no difference in clinical or radiographic outcomes between cemented and uncemented TKR including routine patella resurfacing at two years. Early results suggest there is no difference between cemented and uncemented TKR at 2 years with reference to survivorship, patient outcomes and radiological parameters


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_2 | Pages 35 - 35
1 Jan 2016
Hedley A
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Introduction. The metal-backed patella was originally designed to address shortcomings found with cemented, all-polyethylene patellae. However, complications relating to an all-polyethylene patella were reported to account for up to half of all knee revisions. At the same time, good fixation with bone ingrowth was observed in both titanium and cobalt chromium porous-coated patellae. The advantages provided by using a metal-backed patella, such as uniform load sharing, decreased polyethylene deformation, and potential for biological fixation, may be unjustly outweighed by the fear of patellar component failure; high rates of failure have not been inherent to all metal-backed patella designs. Over the past decade, we have used a metal-backed patella design with excellent results that may be due largely to the design features of the component. Also, we believe there are certain selection criteria that should be strictly adhered to when implanting metal-backed patellae. Correct selection criteria and improved component design strongly indicate the use of press-fit metal-backed patellae. Methods. This single-center study was designed to conduct clinical and independent radiographic review of primary metal-backed, press-fit patella patients with a minimum five-year follow-up. Potential patients were recruited from a group of existing metal-backed patella patients within the principal investigator's medical practice. All patients recruited for this study were required to have undergone primary knee replacement surgery at least five years prior to clinical and radiographic evaluation. Patients were included if they had a diagnosis of noninflammatory degenerative joint disease. Patients with a BMI >40 were excluded from this study. Radiographic analysis was conducted by an independent reviewer according to the current Knee Society Total Knee Arthroplasty Roentgenographic Evaluation and Scoring System. Any radiographs that the reviewer deemed questionable were shown to a second independent orthopaedic surgeon for review, comment, and validation of observations. Kaplan-Meier survivorship was determined for all metal-backed patellae. For survival analysis, only knees with radiographic data were included (74 knees). KSS, WOMAC, and SF-36 scores were calculated also. Results. Seventy-four patients (88 knees) were enrolled in the study, 31 women (41.2%) and 43 men (58.1%). At the time of surgery, the average age was 59.7 years (range, 40–86 years), and the average BMI was 30.6 (range, 19.1–39.6). The breakdown of patients who completed the study and those who were lost to follow-up is shown in Table 1. One metal-backed patella was revised at 49 months for loosening at the bone/implant interface. Survivorship of the metal-backed patellae at minimum five-year follow-up was estimated to be 93.95% with bounds of 73.61% and 98.74%. No radiolucencies greater than 1 mm were observed in any radiographs (Fig. 1), with the exception of the one revision case. Conclusion. Our experience with this metal-backed patella design has been excellent. Failure does not occur due to dissociation of the plastic. As the porous coating is almost under constant compression, biological fixation is assured in most instances, as confirmed by our minimum five-year radiological results. Improved component design and adherence to the correct patient selection criteria absolutely indicate the use of press-fit metal-backed patellae


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_8 | Pages 27 - 27
1 May 2019
Gustke K
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Total knee replacements are being more commonly performed in active younger and obese patients. Fifteen-year survivorship studies demonstrate that cemented total knee replacements have excellent survivorship, with reports of 85 to 97%. Cemented knee arthroplasties are doomed to failure due to loss of cement-bone interlock over time. Inferior survivorship occurs in younger patients and obese patients who would be expected to place increased stress on the bone-cement interfaces. Roentgen stereophotogrammetric analysis (RSA) studies have indicated that cementless fixation should perform better than cemented fixation. However, cementless fixation for total knee replacement has not gained widespread utilization due to the plethora of poor results reported in early series. The poor initial results with cementless total knee replacement have occurred due to poor implant designs such as cobalt chrome porous interfaces, poor initial tibial component stability, lack of continuous porous coating, poor polyethylene, and use of metal-backed patellae. I have used cementless fixation for total knee replacements for young, active, and heavy patients since 1986 when durability over 20 years is desirable. My series of over 1,300 cementless TKAs represents about 20% of the 6,500 total knees I have performed from 1986 to 2017. I have seen initial failures in my series due to the use of metal-backed patellae with thin polyethylene, older generation polyethylene, and use of screws with the tibial components which provide access to the metaphyseal bone for polyethylene wear debris. Overall implant fixation failures were still significantly low due to the use of a highly porous titanium surface on both the tibial and femoral components. With the advent of utilizing implants with continuous porous surfaces and highly crosslinked polyethylene, and elimination of use of metal-backed patellae and tibial screws, I have only had one revision due to aseptic loosening or osteolysis in the last 1,071 cases performed since 2002. Almost 50% of total knees are now performed on patients under the age of 65. A 55-year-old patient has a 30 year life expectancy. Modern total knee replacement design has made biological fixation predictable for young and heavy patients. Because it is a biological interface, it should respond better than cement to the increased stresses that will be applied over many years by our younger, more active and heavier total knee population


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_17 | Pages 25 - 25
1 Nov 2016
Gustke K
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Total knee replacements (TKRs) are being more commonly performed in active younger and obese patients. Fifteen year survivorship studies demonstrate that cemented total knee replacements have excellent survivorship, with reports of 85% to 97%. However, inferior survivorship occurs in younger patients and obese patients who would be expected to place increased stress on the bone cement interfaces. Cementless fixation for total knee replacement has not gained widespread utilization due to the plethora of poor results reported in early series. These poor results do not reflect that cementless fixation is not obtainable, since an almost universal acceptance of cementless fixation for total hip replacement has shown. A Cochrane database study of total knees with roentgen stereophotogrammetric analysis (RSA) demonstrated that the risk of future aseptic loosening should be 50% less with cementless fixation. The poor initial results with cementless total knee replacement have occurred due to poor implant designs such as cobalt chrome porous interfaces, poor initial tibial component fixation, lack of continuous porous coating, poor polyethylene, and use of metal-backed patellae. I have used cementless fixation for total knee replacements for young, active, and heavy patients since 1986 when durability over 20 years is desirable. My series of over 1,000 cementless TKRs represents about 20% of the total knees I have performed from 1986 to 2015. I have seen failures in my series due to the initial use of metal-backed patellae with thin polyethylene and use of screws and femoral and tibial components which provide access to the metaphyseal bone for polyethylene wear debris. Overall failures were still significantly low due to the use of highly porous titanium surfaces on the tibial and femoral components. Isolated aseptic loosening only occurred on one tibial component in my entire series. With the advent of utilizing implants with continuous porous surfaces and highly cross-linked polyethylene, and elimination of use of metal-backed patellae and tibial screws, I have only had one revision due to aseptic loosening or osteolysis in the last 760 cases performed since 2002. Almost 50% of total knees are now performed on patients under the age of 65. A 55-year-old patient has a 30-year life expectancy. Modern total knee replacement design has made biological fixation predictable for young and heavy patients. Because it is a biological interface, it should respond better than cement to the increased stresses that will be applied over many years by our younger, more active and heavier total knee population


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_4 | Pages 52 - 52
1 Mar 2021
Harris A O'Grady C Sensiba P Vandenneucker H Huang B Cates H Christen B Hur J Marra D Malcorps J Kopjar B
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Patients ≤ 55 years have a high primary TKA revision rate compared to patients >55 years. Guided motion knee devices are commonly used in younger patients yet outcomes remain unknown. In this sub-group analysis of a large multicenter study, 254 TKAs with a second-generation guided motion knee implant were performed between 2011–2017 in 202 patients ≤ 55 years at seven US and three European sites. Revision rates were compared with Australian Joint Registry (AOANJRR) 2017 data. Average age 49.7 (range 18–54); 56.4% females; average BMI 34 kg/m2; 67.1% obese; patellae resurfaced in 98.4%. Average follow-up 4.2 years; longest follow-up six years; 27.5% followed-up for ≥ five years. Of eight revisions: total revision (one), tibial plate replacements (three), tibial insert exchanges (four). One tibial plate revision re-revised to total revision. Revision indications were mechanical loosening (n=2), infection (n=3), peri-prosthetic fracture (n=1), and instability (n=2). The Kaplan-Meier revision estimate was 3.4% (95% C.I. 1.7% to 6.7%) at five years compared to AOANJRR rate of 6.9%. There was no differential risk by sex. The revision rate of the second-generation guided motion knee system is lower in younger patients compared to registry controls


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 9 - 9
1 Jan 2004
Burroughs B O’Connor D Sargent M Muratoglu O Rubash H Freiberg A Estok D Jasty M Harris W Deluzio K Krevolin J Wyss U Shen M
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A high proportion of complications following TKR occur at the patellofemoral articulation secondary to delami-nation and adhesive/abrasive wear. Electron beam cross-linking and melting has been shown to substantially reduce delamination and adhesive/abrasive wear in polyethylene tibial inserts. A series of in-vitro patella wear and fatigue tests were developed to explore the benefits of this material at the patellofemoral articulation. Patellae (NKII, Sulzer Orthopedics, Inc., Austin, TX) were tested on an AMTI (Watertown, MA) knee simulator articulating against the trochlear grove of the femoral component. The simulator controlled flexion/ extension and patellofemoral contact force. Each test included patellae manufactured from conventional and electron beam crosslinked and melted polyethylene. Three different simulations were created: i) normal gait (5 million cycles) with optimal component alignment, ii) stair climbing (2 million cycles) with optimal component alignment, iii) stair climbing (2 million cycles) with 4° of femoral component internal rotation to simulate a component malalignment condition. In the last two simulations all patellae were artificially aged for 35 days in 80°C air to simulate one aspect of the long term oxidative state of each material. In normal gait, the unaged conventional and highly cross-linked materials demonstrated similar behaviour. In stair climbing with optimal component alignment, the aged conventional patellae developed cracks by 2 million cycles. In stair climbing with component malalign-ment the aged conventional patellae developed cracks and delamination by 1 million cycles. None of the highly cross-linked components showed cracks or delamination. These results demonstrate the potential advantage of highly cross-linked polyethylene for the patella


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_7 | Pages 88 - 88
1 Apr 2017
Barrack R
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Resurfacing the patella is performed the majority of the time in the United States and in many regions it is considered standard practice. In many countries, however, the patella is left un-resurfaced an equal amount of the time or even rarely ever resurfaced. Patella resurfacing is not a simple or benign procedure. There are numerous negative sequelae of resurfacing including loosening, fragmentation, avascular necrosis, lateral facet pain, stress fracture, acute fracture, late fracture, and restricted motion. In a study by Berend, Ritter, et al, failures of the patella component were reported 4.2% of the time at an average of only 2.6 years. A study was undertaken at Washington University in recent years to determine rather more clinical problems were observed following total knee replacement with or without patella resurfacing. Records were maintained on all problem total knees cases with well localised anterior knee pain. The referral area for this clinic is St. Louis which is among the largest American cities, with the highest percentage of total knees that are performed without patella resurfacing. During 4 years of referrals of total knee patients with anterior knee pain, 47 cases were identified of which 36 had a resurfaced patella and 11 had a non-resurfaced patella. Eight of 36 resurfaced patellae underwent surgery while only 2 of 11 non-resurfaced patellae underwent subsequent surgery. More than 3 times as many painful total knees that were referred for evaluation had already had their patella resurfaced. In spite of the fact that approximately equal number of total knees were performed in this area without patella resurfacing, far more patients presented to clinic with painful total knee in which the patella had been resurfaced. The numerous pathologies requiring a treatment following patella resurfacing included patella loosening, fragmentation of the patella, avascular necrosis patella, late stress fracture, lateral facet pain, oblique resurfacing, and too thick of a patellar composite. In a large multi-center randomised clinical trial at 5 years from the United Kingdom in over 1700 knees from 34 centers and 116 surgeons, there was no difference in the Oxford Score, SF-12, EQ-5D, or need for further surgery or complications. The authors concluded, “We see no difference in any score, if there is a difference, it is too small to be of any clinical significance”. In a prospective of randomised clinical trial performed at Tulane University over 20 years ago, no differences were observed in knee score, a functional patella questionnaire, or the incidence of anterior knee pain between resurfaced and un-resurfaced patellae at time intervals of 2–4 years, 5–7 years, or greater than 10 years. Beyond 10 years the knee scores of total knee patients with a resurfaced patella had declined significantly greater than those with a non-resurfaced patella. There are numerous advantages of not resurfacing the patella including less surgical time, less expense, a lower risk of “major” complications (especially late complications), and if symptoms develop in an un-resurfaced patella, it is an easier salvage situation with more options available. A small percentage of total knee patients will be symptomatic whether or not their patella is resurfaced. Not resurfacing the patella retains more options and has fewer complications. The major determinant of clinical result and the presence of anterior knee pain after knee replacement is surgical technique and component design not whether or not the patella is resurfaced. Patella resurfacing is occasionally necessary for patients with inflammatory arthritis, a deformed or maltracking patella, or symptoms and pathology that are virtually restricted to the patellofemoral joint. For the vast majority of patients, however, patella resurfacing is not necessary


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 95 - 95
1 Mar 2006
Harman M Markovich G Banks S Hodge W
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Introduction: Patellar complications after total knee arthroplasty (TKA) remain a common reason for failure. Fully congruent patellar components, with larger contact areas and a polyethylene articular surface that is free to rotate in the frontal plane (LCS design), were designed to accommodate patellar mechanics and decrease wear. However, it remains to be determined whether the perceived advantages of a mobile-bearing, fully congruent patella design are realized in-vivo. The purpose of this study is correlate wear patterns on congruent mobile-bearing patellar components with patellar mechanics that existed after TKA. Methods: Uncemented metal-backed patellar components were retrieved at revision surgery from 26 knees with meniscal bearing (23 knees) and rotating platform (3 knees) LCS mobile bearing prostheses (DePuy Orthopaedics). Mean patient age and time in-situ was 75+11 years and 11+4 years, respectively. Revision reasons included bearing wear (11), patella wear (7), instability (2), pain (3), loosening (1), osteolysis (1), and unknown (1). Polyethylene damage was assessed using optical microscopy. Articular wear area was measured using digital image analysis and the % area, location and incidence of each damage mode was calculated. Results: The average damage area on the retrieved patella occupied 69%+15% of the surface. Burnishing, delamination and scratching modes occupied the largest areas. Delamination was noted on 58% of the retrieved patellae, predominantly located in the superior-medial quadrant. Nine (35%) patellae were fractured, with the fracture plane typically oriented in the medial-lateral direction or along the lateral edge. Twently one (81%) patellae had subsurface cracks oriented along the superior-inferior axis on the extreme lateral edge and along the medial-lateral axis. None of the patellae had embedded third body debris, but the embedded superior metal pin was exposed due to extreme damage in 4 patellas. The original femoral and tibial components were left in-situ in all knees at the time of revision, such that only the polyethylene tibial and patellar articulations were exchanged. Discussion: Despite severe wear of the components, there was only a 5% incidence of osteolysis noted intra-operatively. Cyclic compressive and tensile forces during knee flexion likely caused initiation and propagation of cracks resulting in patellar bearing fracture. The delami-nation patterns on the retrieved patellae are consistent with bearing rotation into an incongruent bearing position during knee flexion, with presumably high contact stresses occurring in the delaminated superior-medial quadrant. Fully congruent mobile-bearing patella components must maintain mobility between the articular surface and metal back so that areas of incongruent contact, and associated high contact stresses and delamination, do not occur during in-vivo function


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 124 - 124
1 Mar 2010
Rosenstein A Postak PD Greenwald S
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INTRODUCTION: Following Total Knee Arthroplasties, patellofemoral complications have shown to be responsible for approximately 50% of re-operations. Contemporary patellar designs employ both “onlay” and “inset” configurations. The latter promotes ease of placement, reduced bone removal and a heralded theoretic advantage of increased strength at the fixation interface. However, to date, no reports have compared the disassociation strengths of these two patellar component modes of fixation. The purpose of this study is to quantify the shear disassociation strength for both onlay and inset patellar fixation techniques. METHODS: Two sets of synthetic solid foam patellae were prepared using standard milling techniques for symmetrical, three-peg onlay and inset polyethylene cylinders of identical dimension. The use of synthetic bones in mechanical testing was validated in the past. The cylinders were cemented to the synthetic patellae, using standard cementing techniques. The fixation resistance of both groups was measured using an Instron Testing Machine. A compressive joint force simulating chair rise was applied perpendicular to the anterior surface of the patellar component model. A shearing displacement was then applied to the composite until patellar component disassociation. RESULTS: The mean shear strength of the onlay group was 2540 N SD 236 N, (n=7) and 3180 N SD 186 N, (n=6) for the inset group. The inset patellae was 25% (640 N) stronger than the onlay patellae, (p=0.0002, two-tailed student t-test). DISCUSSION/CONCLUSION: The results of the study demonstrated a significantly higher resistance of inset patellar fixation to shear stress compared to onlay patellar fixation. Although further in-vivo studies are indicated, the data suggests that the use of inset patella in total knee replacements may offer stronger fixation and consequently decreasing morbidity associated with patella implant loosening


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_17 | Pages 53 - 53
1 Nov 2016
Barrack R
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Resurfacing the patella is performed the majority of the time in the US and in many regions it is considered standard practice. In many countries, however, the patella is left unresurfaced an equal amount of the time or even rarely ever resurfaced. Patella resurfacing is not a simple or benign procedure. There are numerous negative sequelae of resurfacing including loosening, fragmentation, avascular necrosis, lateral facet pain, stress fracture, acute fracture, late fracture, and restricted motion. In a study by Berend, Ritter, et al, failures of the patella component were reported 4.2% of the time at an average of only 2.6 years. A study was undertaken at Washington University in recent years to determine whether more clinical problems were observed following total knee replacement with or without patella resurfacing. Records were maintained on all problem total knees cases with well localised anterior knee pain. The referral area for this clinic is St. Louis which is among the largest American cities, with the highest percentage of total knees that are performed without patella resurfacing. During 4 years of referrals of total knee patients with anterior knee pain, 47 cases were identified of which 36 had a resurfaced patella and 11 had a non-resurfaced patella. Eight of 36 resurfaced patellae underwent surgery while only 2 of 11 non-resurfaced patellae underwent subsequent surgery. More than 3 times as many painful total knees that were referred for evaluation had already had their patella resurfaced. In spite of the fact that approximately equal number of total knees were performed in this area without patella resurfacing, far more patients presented to clinic with painful total knee in which the patella had been resurfaced. The numerous pathologies requiring a treatment following patella resurfacing included patella loosening, fragmentation of the patella, avascular necrosis patella, late stress fracture, lateral facet pain, oblique resurfacing, and too thick of a patellar composite. In a large multi-center randomised clinical trial at 5 years from the United Kingdom in over 1700 knees from 34 centers and 116 surgeons, there was no difference in the Oxford Score, SF-12, EQ-5D, or need for further surgery or complications. The authors concluded, “We see no difference in any score, if there is a difference, it is too small to be of any clinical significance”. In a prospective randomised clinical trial performed at Tulane University over 20 years ago, no differences were observed in knee score, a functional patella questionnaire, or the incidence of anterior knee pain between resurfaced and unresurfaced patellae at time intervals of 2–4 years, 5–7 years, or greater than 10 years. Beyond 10 years the knee scores of total knee patients with a resurfaced patella had declined significantly greater than those with a non-resurfaced patella. There are numerous advantages of not resurfacing the patella including less surgical time, less expense, a lower risk of “major” complications (especially late complications), and if symptoms develop in an unresurfaced patella, it is an easier salvage situation with more options available. A small percentage of total knee patients will be symptomatic whether or not their patella is resurfaced. Not resurfacing the patella retains more options and has fewer complications. The major determinant of clinical result and the presence of anterior knee pain after knee replacement is surgical technique and component design not whether or not the patella is resurfaced. Patella resurfacing is occasionally necessary for patients with inflammatory arthritis, a deformed or maltracking patella, or symptoms and pathology that are virtually restricted to the patellofemoral joint. For the vast majority of patients, however, patella resurfacing is not necessary


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 457 - 457
1 Sep 2009
Green C Flavin R Fitzpatrick D Moran R
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Graft choices for revision anterior cruciate ligament (ACL) reconstruction and complex ligament reconstructions of the knee are controversial. The aim of our study was to analyze the biomechanical effect of harvesting bone plugs from both the distal and proximal poles of the patella, to simulate a simultaneous harvesting of a Bone – Patellar Tendon – Bone and Quadriceps Tendon – Bone grafts, in a transverse stress environment. Sixty Bovine Patellae were analysed. They were divided into 4 groups – based on the residual bone bridge (percentage of total length of patella) remaining after bone plug resection. 0 – 10%, 11 – 20%, 21 – 30% and > 30%. All patellae were tested in a modified 4 – point bending environment, to a maximum load of 10,000N, in a customized designed jig. This method simulates the axial bending stress on the patella during knee flexion. All dimensions of the patellae were recorded including Depth of patella at bone resection and wall thickness adjacent to plug resection site. All patellae with a 0% bone bridge fractured (Ultimate Tensile Strength/UTS) at a mean Tensile Force of 5863N (Range 3140 – 8730N). There was a subgroup of incomplete fractures – extra-articular fractures – which fractured at 6542N (Range 5085 – 9180N). The remaining specimens failed to fracture. Comparing the UTS and the patellar dimensions, using Weibull’s Statistical Analysis we demonstrated that less than 60% bone plug resection carried a very low probability of fracture. This study demonstrates the safe criteria for bone – tendon graft harvesting from both the proximal and distal poles of the patella. With regards to a normal human patella, a 40% bone – bridge is approximately a 20mm bone – bridge. We conclude that the simultaneous harvesting of Bone – Patellar Tendon – Bone and Quadriceps Tendon – bone grafts from a patella has no significant increase in the fracture risk of the patella


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 3 - 3
1 Jan 2004
Markel D Klein R Bushelow M Kester M
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Rotational mal-alignment of the patella-femoral interface will result in increased wear. Highly cross-linked polyethylene will decrease wear even if mal-aligned. A biomechanical model based on high load and flexion was used to measure wear of rotationally aligned and mal-aligned all-polyethylene patellae. The components were articulated against “aligned” and “mal-aligned” (60 internally rotated) femoral components. The patella were subjected to a constant 2224 N force and the femoral components rotated from 600 to 1200 at 1.33 Hz. Patellae of identical geometry made of conventional UHMWPE and highly crosslinked UHMWPE were tested to 1 000 000 cycles. Wear was determined by gravimetric measurement relative to cemented soak controls. Conventional UHMWPE: All samples demonstrated damage (burnishing and scratching) of the articulating surfaces. There was a significant increase in wear (p< .05) in the mal-aligned patella. Highly cross-linked patellae: All components fractured in the mal-aligned construct (gamma irradiated remelted n=6, gamma irradiated and annealed n=2). Failure first occurred at the cement interface then at the posts. Correct femoral rotation is important during TKA. The intertrochlear line, tibial cut, epicondylar axis and posterior condyles are helpful landmarks, but there is still eyeball control of rotation. It is clear from this study that rotational mal-alignment will result in increased polyethylene wear. Highly cross-linked polyethylene has decreased wear in THA. Unfortunately, the decrease in ductility and toughness may make the use of these materials unsuitable for TKA. Based on this study model, patellar components would need to be redesigned if highly cross-linked polyethylene were to be applied. The wear rate of conventional UHMWPE patellae is increased by rotational mal-alignment. Highly cross-linked components were a poor solution to problem. Use of highly cross-linked polyethylene resulted in component fracture


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 444 - 444
1 Apr 2004
Minns RJ Young S Bibb R Moliter P
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The purpose of this study was to characterise accurately, the extent and geometry, and produce representative rigid resin models of full thickness articular cartilage lesions of various types, shapes and sizes on the articular surface of pig patellae. Ten adult pig patellae and three adult Ox patellae were obtained and cleared of adhering tissue. Full thickness lesions were induced from oval shaped to “U” shaped scarifications by careful use of a hand held bur, and the geometry noted by taking appropriate dimensions with a Vernier cailper in the horizontal and vertical planes, and plan view photographs. MRI images using fat-suppressed weighted 1.5 mm thick slices scans in the horizontal plane, were produced in DICOM format for conversion to SLE files used in the reconstruction in the computer. The patellae were then held in a stone plaster mix to produce a male mould of the articular surface. The computer images were generated and the physical dimensions taken with the Vernier calliper were recorded from the reconstructed image in the computer using graphics software. The computer data was used to produce a rigid full scale model of the articular surface in resin using laser stereolithography which is using in the rapid prototyping industry. The resin models were matched with the male plaster moulds to confirm an accurate match of the 3-dimensional shape of the computer generated in all the types of lesions we produced. It is proposed to use the rigid models to produce sterile templates that could be used by surgeons to fashion an area around a lesion using a suitable reamer/bur using a predetermined criteria of cartilage thickness (say 2 mm), and the same geometrical data would be used to produce a suitable semi rigid scaffold shaped to the lesion. Our study has shown that very accurate 3 dimensional data can be quickly processed from MRI images to produce, using current rapid prototyping techniques, templates and implants to fit lesions accurately in the patella. There is no reason why this technology could not be applied to any joint surface that can be accessed by MRI


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_3 | Pages 52 - 52
1 Apr 2018
Huish E Coury J Ummel J Casey J Cohen J
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Introduction. Management of the patellofemoral surface in total knee arthroplasty (TKA) remains a topic of debate. Incidence of anterior knee pain and incidence of repeat operation have been the focus of several recent meta-analyses, however there is little recent data regarding patients” subjective ability to kneel effectively after TKA. The purpose of this study was to compare patient reported outcomes, including reported ability to kneel, after total knee arthroplasty with and without patellar resurfacing. Methods. Retrospective chart review of 84 consecutive patients who underwent primary TKA with patella resurfacing (56 knees) or without patella resurfacing (28 knees) having a minimum of 2.5 year follow up was performed. Oxford knee scores (OKS), visual analog pain scores (VAS), and questionnaires regarding ability to kneel were evaluated from both groups. Inability to kneel was defined as patients reporting inability or extreme difficulty with kneeling. Shapiro-Wilk test was used to determine normality of data. Mann Whitney U test was used to compare the OKS and VAS between groups. Chi square test was used to compare kneeling ability between groups. Statistical analysis was performed with SPSS version 23 (IBM, Aramonk, NY). Results. The 84 patients included 26 males and 58 females with average age 66.5 (range 46–91). Average follow up was 51 months (range 30–85). There was no significant difference in the percentage of female patients (64% vs 79%), age (67.8 vs 63.8), or reoperation rate (4% vs 7%) between the resurfaced and non-resurfaced groups. There was significantly longer follow up in the non-resurfaced group (57 vs 48 months). There was no statistically significant difference between the resurfacing and non-resurfacing group in terms of OKS (39 vs 38) or VAS (2.5 vs 3.0). However, those patients who did not have their patellofemoral joint resurfaced were more likely to report ability to kneel when compared to the resurfacing group (64% vs 39%, p=0.035). Kneeling ability was not correlated with duration of follow up, patient age or VAS. Kneeling ability was higher in female patients (57%) than males (27%), p=0.017. Discussion. There is concern for increased anterior knee pain and reoperation in patients whose patellae are not resurfaced. However, their failure to imnprove after revision to a resurfaced patella has left some room for depate as to whether or not the lack of resurfacing is the cause of their problems. This study did not show any increase in knee pain or reoperation between groups. There was an increased subjective ability to kneel in paients whose patellae were not resurfaced. This may have implications for the subset of paeitnts whose work or hobbies may require kneeling. There have been previous reports that subjective ability to kneel and actual ability may differ, and also that kneeling can be taught by a therapist. Our data also shows that female gender had a higher reported rate of kneeling


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 443 - 443
1 Nov 2011
Leszko F Zingde S Argenson J Mahfouz M Komistek R
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Previosuly, Komistek et al. have shown that the kinematics of the patellofemoral joint is altered after a TKA surgery. Specifically the implanted patella experiences significantly less rotation than the natural patella. Also, in early flexion, the patellofemoral contact positions differed significantly between implanted and non-implanted patellae. It was also found that some of TKA subjects experience patellofemoral separation. These kinematical differences may lead to adverse mechanical conditions and increase fatigue or cause loosening of the implant components. This study’s objective was to determine the three-dimensional patellofemoral kinematics and correlate it with the in vivo sound (vibrations) detected using accelerometers for subjects having a TKA and a non-implanted knee under in vivo, weight bearing conditions. The correlation of the knee mechanical conditions with the vibration data may indicate new parameters that may be used to diagnose the condition of the articular cartilage or implant components. Fifteen subjects (average age 71.8 ±7.4years) having one implanted knee (mobile bearing Hi-Flex PS) and the healthy contralateral knee, performed. deep knee bend to maximum flexion,. chair rise and. stair climb activities under fluoroscopic surveillance. Three miniature, piezoelectric, three-axial accelerometers were attached to the patella and femoral epicondyle. The study was approved by the Institutional Review Board and informed consent was obtained from all subjects. The sensors detected the vibration magnitudes and frequencies of the articulating patellofemoral joint surfaces. The signals were amplified and low-pass filtered at 5 kHz by a signal conditioner. The 3D tibiofemoral and patellofemoral kinematics were derived for both knees using a previously published 3D-to-2D registration technique. The 3D bone models were recovered from CT scans, while implant models were obtained from the manufacturer. The patellofemoral rotations were described using the Grood and Suntay convention. The kinematics and sound data were synchronized and recorded under fluoroscopic surveillance, for 10 patients. Then a subset of seven subjects having a TKA was re-analyzed for their contralateral (non-implanted) knee. The vibration signal was then converted to audible sound and correlated with the 3D kinematics. On average, the subjects achieved more flexion with their TKA (103.4°±15.9°) than with their contralateral knee (96.3°±18.3°). The patellofemoral kinematics varied between the TKA and nonimplanted patella groups; the resurfaced patella experienced less flexion, less medial rotation and less tilt than the contralateral patella. The patellar flexion results were consistent with previously reported literature for both TKA and non-implanted patellae. Also, the resurfaced patellae contacted the femur more proximally than healthy patellae. Audible signals were found for both groups of subjects. The frequency analysis demonstrated that specific frequencies were in similar range for both groups, but the magnitudes and variations were different for the TKA and contralateral knees. This study correlated 3D patellofemoral kinematics with sound under in vivo conditions for three different activities. Variable audible signals were detected for TKA and non-implanted knees. Vibration magnitude and frequency identification, under in vivo conditions, for TKA may lead to a better understanding of wear and failure modes with respect to the patellofemoral mechanics, more specifically, the patellar insert. Currently this initial study is being expanded to degenerated knee joints and failed TKAs for possible applications of the vibration analysis to the early diagnosis of knee arthritis, detection of implant loosening or wear and monitoring of implant osteointegration progress


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 118 - 119
1 Feb 2003
Gill P Keast-Butler O Parikh M Butler-Manuel A
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The aim of this study was to assess the outcome of patients who underwent ElmslieTrillat antero-medial tibial tubercle transfer for treatment of persistent symptomatic anterior knee pain due to chondromalacia patellae. We performed a prospective analysis of 23 patients who underwent Elmslie-Trillat antero-medial tibial tubercle transfers over a five year period for chronic anterior knee pain and an arthroscopic diagnosis of chondromalacia patellae. All patients who presented with anterior knee pain underwent an initial period of physiotherapy and all patients whose symptoms persisted following physiotherapy underwent arthroscopic assessment. Patients who continued to experience debilitating symptoms despite this initial treatment and who also had a diagnosis of chondromalacia patellae from arthroscopic assessment were listed for an Elmslie-Trillat tibial tubercle anteromedialisation. Patients who gave a history of instability or dislocation were excluded. The average age of patients undergoing surgery was 34 years (21–48 years) and the average time between arthroscopic diagnosis and surgery was 14 months. All patients who underwent surgery had pre and post operative KuJala patellofemoral scoring. The average pre-operative score was 54 (30–78) and post operative score 76 (46–100). The average post operative assessment was 25 months (6–62 months). Twenty one patients had improved post operative scores with one having a worse score and one score remaining unchanged following surgery. Nineteen patients felt that their symptoms had improved, three felt that there had been no change and one felt that they were worse after surgery. When asked if the improvement in symptoms had been worthwhile nineteen stated that they would undergo surgery again if in the same situation and four stated that they would not. The treatment of symptomatic chondromalacia patellae remains a challenge. Although a more selective approach to individuals with anterior knee pain is widely advocated in the literature this study demonstrates that good results can still be achieved in patients treated empirically with a tibial tubercle anteromedialisation


Bone & Joint 360
Vol. 1, Issue 5 | Pages 12 - 14
1 Oct 2012

The October 2012 Knee Roundup. 360. looks at: autologous chondrocytes and chondromalacia patellae; drilling the femoral tunnel at ACL reconstruction; whether we repair the radially torn lateral meniscus; factors associated with patellofemoral pain; mechanoreceptors and the allografted ACL; whether high tibial osteotomy can delay the need for knee replacement; return to sport after ACL reconstruction; tissue-engineered cartilage; and the benefits of yoga


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 468 - 468
1 Sep 2009
Sadoghi P Glehr M Schuster C Kränke B Schöllnast H Pechmann M Quehenberger F Windhager R
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Whereas thermography has already been used as an assessment of disease activity in some kinds of inflammatory arthritis, it is a new method for objektive pain evaluation in patients with joint prosthesis. To our knowledge, no study has tested the correlation between increase of temperature and anterior knee pain with total knee prosthesis yet. Thirteen patients were included in this study who suffered from anterior knee pain of the retinaculum patellae with total knee prosthesis. The patients were asked to walk 3 km before entering a room which was cooled down to 20 degrees Celsius. A black 1 cm times 4.5 cm square stripe was attached on the diameter of the patella and the patients rested for 20 minutes to cool down before thermographic fotos were taken from 90 degrees, 45 degrees, frontal medial and lateral. The evaluation of temperature difference of each side was performed by marking a 1cm times 2cm square field rectangular around the black stripe and comparing it with a reference point of the same size 3 cm distal of the field. The patients were compared with thirteen others, not suffering from anterior knee pain. Statistical analysis was performed using a t- test and a p value < 0.05 was considered to be significant. The temperature differences between the rectangular field and the reference point increased significantly on the medial (p= 0.00037) or lateral (p= 0.000002) pain side of the knee. The thirteen knees with knee pain had significantly higher temperature differences between medial and lateral temperature differences, than the knees without knee pain. We demonstrate a significant correlation between anterior knee pain and an increase of superficial skin temperature around the retinaculum patellae. To our knowledge, this is the first report of an objective assessment of pain of the retinaculum patellae with total knee prosthesis


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 96 - 96
1 Feb 2020
Harris A Christen B Malcorps J O'Grady C Sensiba P Vandenneucker H Huang B Cates H Hur J Marra D Kopjar B
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Introduction. Patients ≤ 55 years have a high primary TKA revision rate compared to patients >55 years. Guided motion knee devices are commonly used in younger patients yet outcomes remain unknown. Materials and Methods. In this sub-group analysis of a large multicenter study, 254 TKAs with a second-generation guided motion knee implant (Journey II Bi-Cruciate Stabilized Knee System, Smith & Nephew, Inc., Memphis) were performed between 2011–2017 in 202 patients ≤ 55 years at seven US and three European sites. Revision rates were compared with Australian Joint Registry (AOANJRR) 2017 data. Results. Average age 49.7 (range 18–54); 56.4% females; average BMI 34 kg/m. 2. ; 67.1% obese; patellae resurfaced in 98.4%. Average follow-up 4.2 years; longest follow-up six years; 27.5% followed-up for ≥ five years. Of eight revisions: total revision (one), tibial plate replacements (three), tibial insert exchanges (four). One tibial plate revision re-revised to total revision. Revision indications were mechanical loosening (n=2), infection (n=3), peri-prosthetic fracture (n=1), and instability (n=2). The Kaplan-Meier revision estimate was 3.4% (95% C.I. 1.7% to 6.7%) at five years compared to AOANJRR rate of 6.9%. There was no differential risk by sex. Discussion. Reasons for high TKA revision rates in younger patients remain unknown. Conclusion. The revision rate of the second-generation guided motion knee system is lower in younger patients compared to registry controls


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 249 - 249
1 Jul 2011
McWalter EJ Wilson DR Harvey WF Lamb KA McCree PI Hunter DJ
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Purpose: Patellar bracing is a common, mechanical-based treatment strategy for patellofemoral osteoarthritis (OA). It is thought that the brace corrects patellar tracking, however, this correction has not been quantified in the OA population. Through advances in magnetic resonance imaging (MRI), we can now assess patellar tracking in three-dimensions. Method: We assessed three-dimensional patellar tracking in ten subjects with symptomatic radiographic patellofemoral knee OA using a validated, quasi-static, MRI-based method. Four conditions were studied:. no knee brace, no load,. no knee brace, 15% bodyweight (BW) load,. knee brace, no load,. knee brace, 15% BW load. Patellar tracking (flexion, spin and tilt; proximal, lateral and anterior translation) was assessed. Comparisons were made at 1° increments over the coincidental range of knee flexion between the no-brace and brace conditions, at no load and 15% BW load, using a paired t-test with Bonferroni correction. Results: All subjects (7 female, 3 male, 60.9±1.3 yrs, 89.5±19.3 kg) had radiographic lateral patellofemoral OA and seven had concomitant tibiofemoral OA (KL grade≥2). Under no load, the brace extended (mean=2.7°, CI=[2.4°, 2.9°], P< 0.001) and medially tilted (mean=−1.4°, CI=[−1.6°, −1.2°], P< 0.001) the patellae and shifted them distally (mean=0.8mm, CI=[0.6mm, 0.9mm], P< 0.001), medially (mean=0.5mm, CI=[0.5mm, 0.6mm], P< 0.001) and posteriorly (mean=0.6mm, CI=[0.5mm, 0.6mm], P< 0.001). Under 15% BW load, the brace extended the patella (mean=2.4°, CI=[2.1°, 2.8°], P< 0.001) and shifted them distally (mean=1.3mm, CI=[1.1mm, 1.4mm], P< 0.001), medially (mean=0.8mm, CI=[0.7mm, 0.9mm], P< 0.001) and posteriorly (mean 0.6mm, CI=[0.5mm, 0.7mm], P< 0.001). Conclusion: The brace extended the patellae for both loading conditions, suggesting that patellar flexion/extension is restricted by the brace. The brace tilted the patellae medially under no load only, suggesting when the quadriceps are active (15% BW load) the brace has little effect for tilt. While the effect of bracing on patellar tracking may appear small, the differences are of similar magnitude to those observed between normals and patients with patellofemoral pain, suggesting that braces may produce clinically significant changes in patellar tracking


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 470 - 470
1 Apr 2004
Markel D
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Introduction A biomechanical model was developed to measure wear of all-polyethylene patellar components as it relates to femoral component mal-rotation. The model, based on high load and flexion activities such as stair climbing, was used to differentiate the effects of femoral mal-rotation and differing materials on a single patellar design. Methods The patellar components (Scorpio®, Stryker-Howmedica-Osteonics) were cemented onto metal fixtures and articulated against “aligned” and “mal-aligned” (six degrees internally rotated) femoral components. The patellar components were subjected to a constant force and articulated against femoral components flexing from 600 to 1200. Patellae of identical geometry, made of conventional and highly cross-linked ultra-high molecular weight polyethylene, were tested to 1x106 cycles. Following testing, patellar wear was determined by gravimetric measurement relative to soaked control specimens. Results All conventional polyethylene patellae demonstrated damage in the form of burnishing and scratching of the articular surface. The mal-aligned conventional ultra-high molecular weight patellae demonstrated increased weight loss or wear relative to the aligned components (p=.048). All rotationally mal-aligned highly cross-linked polyethylene components sustained polyethylene fracture or catastrophic failure of the cement-polyethylene construct. Conclusions Rotational mal-alignment of the femoral component will result in increased wear of polyethylene patellar components. The newer highly cross-linked materials failed to resolve this wear problem and sustained catastrophic failure when mal-aligned. Attention needs to be given to the patella-femoral articulation when implanting knee components and when developing new polyethylene as the forces in this articulation may result in polyethylene behaviour that varies dramatically from the femoraltibial articulation. In relation to the conduct of this study, one or more of the authors has received, or is likely to receive direct material benefits


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 256 - 256
1 Jul 2008
LECLERCQ S
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Purpose of the study: The stability of the patella over the femur depends on several factors, one being the rotatory freedom of the tibia. Femorotibial rotatory laxity of a total knee arthroplasty (TKA) can be:. dictated by the congruence of the polyethylene in an ultracongruent plateau;. completely free, depending solely on the ligament structures in a self-aligning prosthesis;. the consequence of a compromise between the two, using a semi-constrained prosthesis. With the OMNIA system, the unique femoral piece can be combined with a Wallaby ultracongruent plateau (WUC), a self-aligning mobile plateau (SAL), or a semiconstrained plateau with preservation of the posterior cruciate ligament (Wallaby 1, W1). A comparative study of these three prostheses was performed to evaluate the influence of femorotibial rotatory constraint on patellar stability. Material and methods: The series included 157 TKA: 68 SAL,44 WUC and 45 W1. The same surgeon operated all patients in three successive series. The operative technique was the same using the same instrument set. The femoral piece was inserted first with an automatic rotation systematically set at 5° with the posterior condyles. The knees were varus (71%), valgus (20%) and perfectly aligned (9%). A patellar prosthesis was used in only 10.8% due to excessive wear as assessed intraoperatively. A medial approach was used for the varus knees and a lateral approach for the valgus knees greater than 10°, independently of preoperative patellar stability. Radiological outcome was assessed on the 30° femoro-patellar views. Patellae tilted more than 3° and/or offset more than 5 mm were considered to be excentered. Results: In the SAL group, 55 patellae were centered and 13 off-centered. The ratio was 36 for 6 in the WUC group and 39 for 6 in the W1 group. The percentages of centered patellae were respectively 80, 85, and 86%. The difference was not significant (p=0.66. For knees with preoperative genu varum, the percentages of centered patella were 83, 84, and 86%; and for genu varum, 72, 0 and 75% (sample too small for statistical significance). Discussion: The use of rotatory constraint for TKA does not affect patellar stability. This was confirmed in a subpopulation of genu varum knees and not in genu valgum