The purpose of this study was to assess whether
the use of a joint-sparing technique such as curettage and grafting was
successful in eradicating
Aims.
Aims. To investigate the benefits of denosumab in combination with nerve-sparing surgery for treatment of sacral
We investigated whether the presence of a pathological
fracture increased the risk of local recurrence in patients with
a
Aims.
A
Aims. Tenosynovial
Introduction: Following intralesional resection of
Aims. We performed a systematic literature review to define features of patients, treatment, and biological behaviour of multicentric
Aims. The present study investigated receptor activator of nuclear factor kappa-Β ligand (RANKL), osteoprotegerin (OPG), and Runt-related transcription factor 2 (RUNX2) gene expressions in
Aims. Local recurrence remains a challenging and common problem following curettage and joint-sparing surgery for
Aims.
Background. Tenosynovial
Introduction:
We retrospectively studied local recurrence of
Objectives: Development a
Purpose. Secondary degenerative changes of the knee are a well recognized complication of
Because of the lack of a suitable in vivo model for
Aims. Tenosynovial
Following intralesional resection of
AIM. To present our experience in patients treated under primary diagnosis
Aim: To investigate the outcome of our management of patients with
Aims. There is a lack of evidence about the risk factors for local recurrence of a
It has become standard practice in our unit to treat large
Introduction:
Aims. The aim of this paper was to investigate the prognostic factors for local recurrence in patients with pathological fracture through
Aims. The aim of this study was to evaluate health-related quality of life (HRQoL) and joint function in tenosynovial
Objective: To report the use of a pedicled patellar transplant (d’ Aubigne procedure) in the reconstruction of femoral condyle for unicondylar
Introduction:
Introduction and Aims: The treatment of
Introduction:
Introduction:
Goals: Sarcomatous degeneration of
Background.
Background: Giant-cell tumour (GCT) of bone is a benign but aggressive tumour, usually treated by radical surgical curettage. Surgical treatment of GCT involving the ischium is associated with a high local recurrence rate. We describe a case in which serial arterial embolisation and bisphosphonate treatment resulted in radiological healing of the tumour. So far we have avoided surgical treatment. Case Report: A 40-year-old lady was referred to the bone tumour unit following a fall. A plain radiograph of the pelvis revealed a lytic lesion in the ischium, extending into the posterior column of the acetabulum and associated with a pathological fracture. Biopsy confirmed a diagnosis of GCT. Given the anatomic location, the tumour was treated with serial arterial embolisation and intravenous zoledronate infusions. Follow up at one-year shows healing of the lesion, with no radiological evidence of recurrence. The patient has so far avoided surgery. Discussion: Serial arterial embolisation has been described in the treatment of
The
Benign aggressive tumors are common and can be debilitating for patients especially if they are in peri-articular regions or cause pathological fracture as is common for
Introduction: The confocal laser-scanning microscope (CSLM) was recently introduced. We have invented a new transmission type of double pass CSLM. This study is the first report of valuable pathological information related to bone tumor being derived using such microscopy. Methods: The most remarkable characteristic of this microscope is the use of two laser beams twice passing through the specimen. This laser microscope can detect signals from coloring sources such hematoxylin eosin (HE) stain and obtain clear images of the organelles. The images presented here were built up as electronic signals, processed by computer analysis, and stored in frame memory. Specimens of the
Introduction. Local recurrence of
Tartrate-resistant acid phosphatase is contained in multinucleated giant cells of
We report a case of benign
Purpose: