The anterior pelvic plane (APP) angle is often used as a reference to decide pelvic alignment for hip surgeons. However, Rousseau criticised the validness of the APP angles because the APP angles in standing position measured on conventional standing X-ray films never showed correlation with the other pelvic alignment parameters, such as sacral slope (SS). We measured the APP angles, SS and pelvic tilt (PT) on the non-distorted anteroposterior (AP) and lateral digitally reconstructed radiography (DRR) images in supine position (with CT scans) and AP and lateral X-ray images in standing position (with EOS X-ray machine [EOS imaging, Paris, France]) by using of the same EOS software. Our data showed that the pre- and post-operative APP angles correlated with SS and PT in both supine and standing positions. Our non-distorted high quality images and the EOS software revealed these correlations. Therefore, we can still use the APP angles to decide pelvic alignment for patients who undergo total hip arthroplasty (THA). Recent papers demonstrated positional or chronological dramatic changes of the APP angles between pre- and post-operative states in patients who underwent THA. The EOS system will be a powerful tool to investigate these changes of the pelvic alignments.

Introduction

The safe zone of the acetabular cup for THA was discussed based on the AP X-ray films of hip joints. A supine position is still used to determine the cup position for CAOS such as navigation systems. There were few data about the implant positions after THA in standing positions. The EOS X-Ray Imaging Acquisition System (EOS system) (EOS imaging Inc, Paris, France) allows image acquisition with the patients in a standing or sitting position. We can obtain AP and lateral X-ray images with high-quality resolution and low dose radiation exposure. Recently, we have obtained the EOS system for the first time in Japan. We investigated 3D accuracy of the EOS system for implant measurements after THA.

An ultra-high molecular weight polyethylene (UHMWPE) is widely used as bearing material in artificial joints, however, UHMWPE wear particles are considered to be a major factor in long-term osteolysis and loosening of implants. The wear particles activate macrophages, which release cytokines, stimulating osteoclasts, which results in bone resorption. The biological activity of the wear debris is dependent on the volume and size of the particles produced. Many researchers reported that the volume and size of particles were critical factors in macrophage activation, which particles in the size range of 0.1–1 mm being the most biological active.

To minimize the amount of wear of UHMWPE and to enlarge the size of UHMWPE wear particle, a nano-level surface texturing on Co-Cr-Mo alloy as a counterface material was invented. Although the generally-used surface for a conventional artificial joint has 10 nm roughness (Surface A), the nano-level textured surface invented has a superfine surface of 1 nm with 3% of groove and dimples against the bearing area. The depths of groove and dimples are less than 50 nm (Surface F).

Pin-on-disc wear tester capable of multidirectional motions was used to verify that the nano-textured surface is the most appropriate for artificial joint. UHMWPE pin with an average molecular weight of 6.0 million was placed in contact with the disc and the contact pressure was 6.0 MPa. The disc and pin were lubricated by a water-based liquid containing the principal constituents of natural synovial fluid. Sliding speed of 12.12 mm/s had been applied for total sliding distance of 15 km.

The superfine surface with nano-level grooves and dimples (Surface F) reduced the amount of UHMWPE wear, this would ensure the long-term durability of artificial joint. The wear particles isolated from lubricating liquid were divided broadly into two categories; one is “simple type” and the other is “complicated type”. The lengths in a longitudinal direction (L_l) and its orthogonal direction (L_s) for each particles (>150) were measured, and the each aspect ratio (= L_l/L_s) was calculated. No significant difference was found in the ratio between simple type and complicated type, and in the distributions of aspect ratios. However, the distributions of L_l, which means the size of UHMWPE wear particle, were dramatically changed by using the nano-textured surface (Figure 2). These results suggest that the nano-textured surface does not change the morphological aspect of UHMWPE particle but enlarges the size of UHMWPE particle.

Cells (RAW264.7, blood, Mouse) were cultured with the particles in supplemented Dulbecco's modified Eagle's medium for 24 h in an atmosphere of 5% CO₂ in air at 37 degrees C, and the quantitative PCR was performed for genetic expression of IL-6 (Figure 3). The wear debris generated on the nano-textured surface inhibited the genetic expression of IL-6, which does not induce the tissue reaction and joint loosening.

Total hip arthroplasty (THA) using minimally invasive surgeries (MIS) now become popular operative procedures. It is not easy to understand geometric information of pelvis and femur in the restricted operative fields during MIS-THA. Recently, THA in supine position comes into the limelight again to place acetabular cups in an optimum position because we can minimise the intra-operative pelvic motion during THA in supine position. To verify the usefulness of supine position, we measured the angels of acetabular trial cups intra-operatively using the CT-based navigation system. The trial cup positions were placed according to a conventional acetabular cup alignment guide. We compared the angles of acetabular trial cups between supine and lateral positions through the same MIS antero-lateral (AL) surgical approach.

Thirty eight hips underwent THA in lateral position (the AL group; average age: 63.9 years old, female: 29 cases, 33 hips, male: 5 cases, 5 hips) and 40 hips underwent THA in supine position (the AL Supine group; average age: 62.2 years old, female 40 cases, 40 hips) were subjected in this study. The single surgeon (the first author) performed all surgeries. We used the Roettinger's modified Watson-Jones approach in both groups. The pelvic registration for navigation was carried out using the CT-fluoro matching procedure with VectorVision Hip (BrainLAB, Germany). After acetabular reaming, the acetabular trial cups were placed into the reamed acetabulum to be at 45 degrees of operative inclination (OI) and at 20 degrees of operative anteversion (OA) using a conventional acetabular cup alignment guide. These angles of the trial cups were measured intra-operatively using the CT-based navigation system, VectorVision Hip. After removing the acetabular trial cup, the acetabular cups were placed using the navigation system. Trilogy cups (Zimmer, USA) and AMS HA shells (JMM, Japan) were used in this study.

The average angles of OI were 45.7 degrees (SD 5.5 degrees) in the AL group and 46.3 degrees (SD 4.6 degrees) in the AL Supine group. The average angles of OA were 30.0 degrees (SD 13.5 degrees) in the AL group and 23.5 degrees (SD 8.2 degrees) in the AL Supine group. The hip numbers whose errors were less than 10 degrees were 13 hips in the AL group and 26 hips in the AL Supine group, respectively. There was significant difference in hip numbers whose errors of angles were less than 10 degrees between the AL and Supine groups. The hip numbers whose errors were less than 5 degrees were 7 hips in the AL group and only 6 hips in the AL Supine group, respectively. There was no significant difference in hip numbers whose errors of angles were less than 5 degrees between the AL and Supine groups. The error values of OI were less than 10 degrees except one hip in both groups. However, the error values of 25 hips in the AL group were more than 10 degrees.

In lateral position, the pelvis easily rotated when the affected lower extremity was extended, externally rotated, and adducted during the femoral preparation in the AL group, which resulted in malalignment of acetabular OA. In contrast, most hips could be set with the error values less than 10 degrees in the AL Supine position because the pelvis could be stabilised on the operative table. In addition, landmarks, such as bilateral antero-superior iliac spines and the symphysis pubis, were palpable in supine position. However, the hips with error values less than 5 degrees were only 6 out of 40 hips even though in supine position. Using MIS techniques, we can provide more stable hip joint just after surgery since the muscles surrounding hip joints can be preserved. We have to place acetabular cups in an optimum position to achieve wide range of hip motion to prevent dislocation and to provide limitation-free daily activities for patients. These data suggests that we should use more accurate guide systems for acetabular cup replacement such as navigation systems, patient specific templates, and patient specific mechanical instruments to place acetabular cups in an optimum position.