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The Bone & Joint Journal
Vol. 104-B, Issue 1 | Pages 59 - 67
1 Jan 2022
Kingsbury SR Smith LK Shuweihdi F West R Czoski Murray C Conaghan PG Stone MH

Aims

The aim of this study was to conduct a cross-sectional, observational cohort study of patients presenting for revision of a total hip, or total or unicompartmental knee arthroplasty, to understand current routes to revision surgery and explore differences in symptoms, healthcare use, reason for revision, and the revision surgery (surgical time, components, length of stay) between patients having regular follow-up and those without.

Methods

Data were collected from participants and medical records for the 12 months prior to revision. Patients with previous revision, metal-on-metal articulations, or hip hemiarthroplasty were excluded. Participants were retrospectively classified as ‘Planned’ or ‘Unplanned’ revision. Multilevel regression and propensity score matching were used to compare the two groups.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLII | Pages 9 - 9
1 Sep 2012
Smith LK Ahmad R Langkamer VG
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224 patients from the Cardiff and Vale NHS Trust who had total knee replacements at the NHS Treatment Centre in Weston-Super-Mare by surgeons from overseas appeared to have significantly worse results than those recorded in the published literature. We wished to establish whether a group of patients treated in the same hospital with the same prosthesis at a similar time by local NHS orthopaedic surgeons in substantive posts would have a similar outcome.

Follow-up of all 214 patients (223 knee replacements) treated in 2004 was conducted with questionnaires, clinical review and x-ray assessment. In cases of no response, contact was made with GPs to establish the outcome of the surgery.

The outcome of all patients was known and of the 125 knee replacements available for clinical review at six years (mean), 119 cases (96%) achieved satisfactory coronal alignment with reference to the published literature. There were six revisions, five for loosening and one for malalignment. The cumulative survival rate for re-operation at six years was 97.2% (95% confidence interval 95.2 to 99.1).

This study shows that the results of total knee replacement performed by a group of NHS orthopaedic surgeons were comparable with other institutions and were significantly better than those reported from the NHS Treatment Centre in Weston-Super-Mare, using the same facilities and implant over the same period of time. This work supports previous recommendations for single surgeon supervision of the patient pathway and appropriate follow-up procedures.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 536 - 536
1 Aug 2008
Smith LK Williams DH Langkamer VG
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Introduction: The rate of homologous blood transfusion following primary total hip replacement (THR) can be as high as 30–40% and is not without risk. Postoperative blood salvage (POS) with autologous blood transfusion may minimize the necessity for HBT but the clinical, haematological and economic benefits have yet to be clearly demonstrated for primary THR.

The aim of this prospective randomized study was to determine if the use of POS affects postoperative haemoglobin and haematocrit values and reduces the rate of homologous blood transfusion. Secondary outcomes measures included length of hospital stay and patient satisfaction. A cost analysis was conducted on the basis of the results.

Methods: Calculations following a preliminary study revealed that 72 patients would be required in each group to detect a significant difference of 0.7 gdL−1 in the post operative haemoglobin level (with power of 80% and an α value of 0.05). The patients were block randomized on reduction of the primary THR, prior to closure, to receive either two vacuum drains or the autologous retransfusion system.

Results: There were 82 patients in the vacuum drain group and 76 patients in the autologous retransfusion group. Haemoglobin and haematocrit values were not significantly different between the groups but significantly fewer patients with the autologous system had a postoperative haemoglobin value < 9.0 gdL−1 (8% vs. 20%, p = 0.035). Significantly fewer patients with the autologous system required HBT (8% vs. 21%, p = 0.022). There was an overall cost saving in this group.

Discussion: This study confirms that POS results in significantly fewer patients with a post-operative Hb below 9.0 gdL−1 and confirms that POS significantly reduces the necessity for homologous blood transfusion following primary THR. As a result, our unit uses the autologous retransfusion system for primary THR.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 502 - 502
1 Aug 2008
Smith LK Williams DH Langkamer VG
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Homologous blood transfusion (HBT) following primary total hip replacement (THR) is not without risk. Postoperative blood salvage (POS) with autologous blood transfusion may minimize the necessity for HBT but the clinical, haematological and economic benefits have yet to be clearly demonstrated for primary THR.

The aim of this randomized prospective study was to determine if the use of POS affects postoperative haemoglobin levels, haematocrit and HBT requirement. Secondary outcomes included length of stay and patient satisfaction. A cost analysis was conducted on the basis of the results. The patients were randomized at the point of reduction of the primary THR to receive either two vacuum drains (82 patients) or an autologous retransfusion system (76 patients).

Haemoglobin and haematocrit values were not significantly different between groups but significantly fewer patients with the autologous system had a postoperative haemoglobin value < 9.0 gdL−1 (8% vs. 20%, p = 0.035). Significantly fewer patients with the autologous system required HBT (8% vs. 21%, p = 0.022). There was an overall cost saving in this group.

This study has shown that use of an autologous retransfusion system for primary THR reduces the necessity for HBT and is cost effective.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 8 | Pages 1092 - 1097
1 Aug 2007
Smith LK Williams DH Langkamer VG

Clinical, haematological or economic benefits of post-operative blood salvage with autologous blood re-transfusion have yet to be clearly demonstrated for primary total hip replacement. We performed a prospective randomised study to analyse differences in postoperative haemoglobin levels and homologous blood requirements in two groups of patients undergoing primary total hip replacement.

A series of 158 patients was studied. In one group two vacuum drains were used and in the other the ABTrans autologous retransfusion system. A total of 58 patients (76%) in the re-transfusion group received autologous blood. There was no significant difference in the mean post-operative haemoglobin levels in the two groups. There were, however, significantly fewer patients with post-operative haemoglobin values less than 9.0 g/dl and significantly fewer patients who required transfusion of homologous blood in the re-transfusion group. There was also a small overall cost saving in this group.