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Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_9 | Pages 35 - 35
1 Sep 2019
Breen A Mellor F Breen A
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Purpose and background

Recent research has identified possible functional biomarkers in chronic, nonspecific back pain (CNSLBP) based on intervertebral kinematics. Although excessive IV-RoM is no longer regarded as a clear motion abnormality, some studies have found subtle kinematic measures such as mid-range laxity and motion sharing inequality to be greater in CNSLBP patients. We studied a group of such patients who were investigated following failed interventions in terms of these subtle measures.

Methods

Thirty-seven patients (mean age 47.5 years SD10.87, F14, M23) with CNSLBP that had recently failed to respond to a range of treatments and 37 healthy controls received passive recumbent lumbar intervertebral flexion assessments following a standardised quantitative fluoroscopy (QF) protocol. Groups were compared for motion sharing inequality (MSI) and variability (MSV) (L2-S1), for level by level laxity and translation, and with reference ranges of these from a separate group of healthy controls (n=54).


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_9 | Pages 46 - 46
1 Sep 2019
Breen A Hemming R Claerbout E Breen A
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Purpose and background

Static plain radiographs at the end of uncontrolled bending are the current standard of care for measuring translatory slip in back pain patients. Quantitative fluoroscopy systems (QF) that employ standardised bending protocols have been found to improve precision and reduce dose, but comparative data are lacking. We compared 4 QF methods with static radiographs in a control population, calculating ranges, population variation and measurement errors over 6 weeks.

Methods

Fifty-four healthy controls (F=22, M=23) received passive recumbent and active weight bearing QF screenings during controlled motion, plus still fluoro imaging in neutral, flexion and extension. The translatory slip of all levels from L2-S1 was determined for each condition using bespoke image tracking codes (Matlab) and pooled to provide means and ranges of variation (+/-1.96SD). The pooled measurement error, or minimal detectable change (MDC95), reflecting the intra subject repeatability over 6 weeks was calculated. Ranges of translation for each level (L2-S1), for each type of motion were also calculated.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_9 | Pages 8 - 8
1 Sep 2019
Breen A Hemming R Mellor F Breen A
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Background

Dynamic measurement of continuous intervertebral motion in low back pain (LBP) research in-vivo is developing. Lumbar motion parameters with the features of biomarkers are emerging and show promise for advancing understanding of personalised biometrics of LBP. However, measurement of changes over time inevitably involve error, due to subjects' natural variation and/or variation in the measurement process. Thus, intra-subject repeatability of parameters to measure changes over time should be established.

Methods

Seven lumbar spine motion parameters, measured using quantitative fluoroscopy (QF), were assessed for intra-subject repeatability: Intervertebral range-of-motion (IV-RoM), laxity, motion sharing inequality (MSI), motion sharing variability (MSV), flexion translation and flexion disc height. Intra-subject reliability (ICC) and minimal detectable change (MDC95) of baseline and 6-week follow-up measurements were obtained for 109 healthy volunteers (54 coronal and 55 sagittal).


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_6 | Pages 11 - 11
1 Feb 2016
Breen A Dupac M Osborne N
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Background and Purpose:

The inability of intervertebral joints to resist perturbation due to laxity is traditionally measured in cadaveric specimens as their neutral zones (NZ). However in patients, quantitative fluoroscopic (QF) examinations substitute the Initial Attainment Rate for this. If these two measures correspond sufficiently, a clinical method for measuring segmental instability is possible. This study explored this by determining the criterion validity of the Initial Attainment Rate against the Dynamic NZ in an unloaded multilevel porcine spine.

Methods and Results:

A 5-segment porcine spine was prepared and mounted on a motorised horizontal motion platform fitted with a digital force gage. Left and right bending moments were calculated about each intervertebral joint for 10 repeated side bends using an inverse dynamics method. The Dynamic NZs and Initial Attainment Rates in the first 10° of platform motion at each level were correlated.

The Initial Attainment Rates were comparable to those found in vivo in healthy controls. Substantial and highly significant levels of correlation between these and Dynamic NZs were found for left (rho= 0.75, p=0.0002) and combined left-right bending (rho=0.72, p=0.0001) and moderate for right bending alone (rho=0.55, p=0.0012).


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_6 | Pages 33 - 33
1 Feb 2016
Breen A Mellor F Breen A Hilton A
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Purpose and Background:

Despite the rise of back pain disability, objective mechanical assessment is generally lacking. Quantification of intervertebral kinematics using fluoroscopy provides objective measurement, but its use in clinical practice has not been assessed. This study reviewed cases referred to one UK site for lumbar spine quantitative fluoroscopic (QF) examinations and compared the reasons for referral with the findings reported.

Methods and Results:

Fifty-seven consecutive referrals were reviewed. Patients underwent passive recumbent and/or weight-bearing active examinations in either the sagittal or both the sagittal and coronal planes. Data were extracted from anonymised QF reports and analysed for patient characteristics, reason for referral, working diagnosis at referral, level(s) of interest, previous surgical procedures and findings reported. Reports were also thematically analysed for key findings.

Most patients had chronic back conditions of moderate or severe intensity. Most (38/57) were male, mean age 47 (SD 13.1) and mean complaint duration 5.4 years (0.3–32 years). They were referred mainly to investigate segmental instability (19/54) or spondylolisthesis (13/54) to inform either surgical referral or conservative management. Instability was reported in only 8/57 cases, but restricted and hypermobile levels in the same patient was also common (13/57). In 11 cases no mechanical abnormality was found.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_6 | Pages 23 - 23
1 Feb 2016
Jones M Morris A Pope A Ayer R Breen A
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Purpose and Background:

The spread of upright MRi scanning is a relatively new development in the UK. However, there is a lack of information about whether weight bearing scans confer any additional useful information for low back conditions.

Methods and Results:

Forty-five patient referrals to the upright MRI Department at the AECC for weight bearing lumbar spine scans between November 1st 2014 and June 30th 2015, and the resulting radiologists' reports were reviewed. Age, gender, clinical history, summary of findings, type of weight bearing scanning performed (sitting, standing, flexion, extension) were abstracted. All patients were scanned in a 0.5T Paramed MRopen scanner and all also received supine lumbar spine sagittal and axial scans.

The patients comprised 18 females and 27 males, mean age 52 years, (SD 15.5). Thirty had leg pain, 6 of which was bilateral. In 15, a stenotic lesion was suspected. Other reasons for referral were; possible malignancy (1), effects of degenerative change (4), spondylolisthesis (2), fracture, (1), previous surgery (3), trauma (1), sacroiliitis (1) and instability (3).

In 12/45 cases, reportable findings were more prominent, and sometimes only identifiable, on weight bearing scans, while in a further 4, the reverse was true. All but one of these involved disruption of the spinal or root canals. Eight of them also involved positional alignment.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_6 | Pages 35 - 35
1 Feb 2016
Mellor F Breen A Thomas P Thompson P
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Purpose and Background:

To compare static and dynamic lumbar intervertebral ranges of motion (IV-RoM) in patients with chronic, nonspecific low back pain with upper and lower cut off values derived from healthy controls when variability and measurement errors were reduced.

Measurements from functional radiographs suffer from high variability and measurement errors, making cut off values for excessive or insufficient motion problematical. This study compared maximum lumbar IV-RoM and maximum IV-RoM at any point in continuous motion sequences in patients with chronic, non-specific back pain with upper and lower cut off values for L2 to L5 from matched controls using quantitative fluoroscopy, where variation and measurement errors were reduced.

Methods and Results:

Participants underwent passive recumbent examinations in the sagittal and coronal planes. Values based on were developed for both maximum and continuous motion in controls (n=40). Fishers exact test was used to analyse proportions of patients whose IV-RoMs exceeded reference values.

For maximum IV-RoM in patients, there were no statistically significant differences between groups for the lower value. Only flexion at L4/5 significantly exceeded the upper value (p=0.03). For continuous IV-RoM, left L3/4 (p=0.01) and right L4/5 (p=0.01) were significantly below the lower cut off values. Both flexion L4/5 (p=0.05) and left L3/4 (p=0.01) were significantly above the upper cut off values.


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_4 | Pages 5 - 5
1 Feb 2014
Mellor F Breen A
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Background and purpose

Investigating inter-vertebral biomechanics in vivo using end-of-range imaging is difficult due to high intra subject variation, measurement errors and insufficient data. Quantitative fluoroscopy (QF) can reliably measure continuous motion but may suffer from contamination from uncontrolled loading and muscle contraction which compromises comparisons between studies and limits interpretation of results. This study presents the methods used to overcome these limitations.

Methods and results

Forty chronic, non-specific low back pain (CNSLPB) patients and 40 matched controls underwent QF using a passive recumbent protocol which standardised the rate and range of trunk rotation, thus reducing intra-subject variation and excluding loading and muscle contraction factors. Left, right, flexion and extension were recorded from L2-5 and vertebral motion registered using image processing algorithms, Resultant continuous inter-vertebral rotation data were normalised to produce proportional contributions of each segment throughout the trunk bend

The expected continuous proportional contributions at each level and direction were determined by calculating reference intervals (mean +/− 2SD) from controls. Prevalence of patients exceeding these ranges was determined and the association with CNSLBP calculated using Chi-squared analysis.

Additionally the variance of the normalised data throughout the continuous motion for each direction was determined and summed to produce an combined number. This was used to measure the difference between patients and controls and entered into ROC curve analysis to investigate discrimination between patients and controls.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_17 | Pages 20 - 20
1 Apr 2013
Breen A Mellor F Breen A
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Study Purpose

A preliminary study to compare continuous sagittal plane lumbar inter-vertebral kinematics in 10 healthy volunteers in recumbent and weight bearing configurations using quantitative fluoroscopy.

Background

There are no direct in-vivo comparisons between continuous weight bearing and non-weight bearing inter-vertebral kinematics in the same healthy individuals. This information will advance our knowledge of spine mechanics and provide reference values for clinical studies.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 230 - 230
1 Mar 2010
Breen A Mellor F Mason€ W Bagust J Fowler J
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Background and Purpose: The majority of non-specific low back pain is presumed to be mechanical in origin. Many interventions, including manipulation, mobilisation, core strengthening and rigid/motion preserving surgery rely on the premise that intervertebral motion is related to pain in some patients, however, there is no reliable in vivo experimental evidence for this. We compared continuous intervertebral motion from quantitative digital fluoroscopic sequences in asymptomatic controls and patients with chronic non-specific low back pain to investigate associations between pain and intervertebral motion.

Methods: Thirty asymptomatic volunteers and 21 patients with chronic non-specific low back pain underwent passive, controlled, recumbent lateral bending motion during video-fluoroscopic screening. These provided 90 and 44 intervertebral levels from L2-L5 respectively for analysis. Vertebrae were registered digitally and automatically tracked throughout the motion. Inter-vertebral rotation phenotypes for each left-right sequence were obtained and analysed for stiffness (inter-vertebral motion of less than 3o), lax appearance and paradoxical motion. A similar population underwent sEMG studies to determine if muscle activity was present during controlled passive recumbent motion. Associations between pain and stiffness, lax appearance and paradoxical motion were calculated from chi-squared distributions. A subset of patients also had MR scans to assess disc degeneration.

Conclusion: Stiffness was observed significantly more frequently in patients with pain, as was paradoxical motion and lax appearance. sEMG activity was very small throughout motion in both groups. MR degeneration was not associated with stiffness in patients. Results must, however, be regarded as preliminary as greater normative referencing, group matching, more extensive kinematic analysis, flexion-extension, weight-bearing, and clinical outcomes studies are needed.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 283 - 283
1 May 2009
Parsons S Harding G Underwood M Breen A Foster N Pincus T Vogel S
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Background: Chronic musculoskeletal pain is a major and costly health problem which is difficult to treat from both patients’ and practitioners’ perspectives. Gaining a greater understanding of patients’ and practitioners’ decision making may be one way of achieving more successful chronic pain consultations.

Aim: To explore the influences on patients’ decision making regarding care seeking, and practitioners’ decision making regarding care delivery for chronic musculoskeletal pain.

Method: In-depth qualitative interview study of chronic musculoskeletal pain patients and of NHS and private, mainstream and CAM practitioners who treat patients. Topic guides were developed which explored, patients’ and practitioners’ beliefs about the causes of pain and expectations of treatment, and the factors influencing decision making within the consultation. All interviews were audio taped and transcribed for analysis, and data was analysed using Framework.

Results: Fifteen patients and 21 practitioners (two GPs, five chiropractors, five osteopaths and 10 physiotherapists) were interviewed. Themes identified as influencing the process of care and decision making, were the level of trust within the patient-practitioner relationship, beliefs about whom should be responsible for patients’ health, the role of patients’ self identity on the management of pain, and beliefs about whom should hold the expertise within the consultation.

Conclusions: To improve primary care for chronic musculoskeletal pain, the level of trust within the patient-practitioner relationship may need to be increased. This may help practitioners to recognise and accept patients’ growing expertise within the consultation, which in turn may facilitate patients in taking more responsibility for their pain.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 282 - 282
1 May 2009
Parsons S Underwood M Breen A Foster N Pincus T Vogel S
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Background – Patients with chronic musculoskeletal pain seek care from a wide range of practitioners, both mainstream and complementary and alternative (CAM). Previous research suggests that patients’ social class and educational level may strongly influence their consulting behaviour. The role of health outcomes in influencing patients’ consulting behaviour has been less frequently studied.

Aims – To explore the relationship between health outcomes and consulting behaviour of chronic musculoskeletal pain patients.

Method – Secondary analysis of data collected as part of a population questionnaire survey of chronic pain. Univariate and multi variate analyses were undertaken to explore the relationship between health outcomes (e.g. health related quality of life) and consulting behaviour.

Results – The survey response rate was 62% and the prevalence of chronic pain was 38% (987/2504). 53% of patients had consulted mainstream practitioners only, 4% CAM practitioners only, 18% mainstream and CAM practitioners and 25% no one.

Patients’ who had consulted both mainstream and CAM practitioners reported the poorest health outcomes (EQ 5D = 0.55), followed by those who consulted just mainstream practitioners (EQ 5D = 0.61), and those who had consulted no one (EQ 5D = 0.72). The best health outcomes were reported amongst those who had just consulted CAM practitioners (EQ 5D =0.78). In multivariate analyses, the most powerful predictors of consulting both mainstream and CAM practitioners were working and having high levels of pain related disability.

Conclusions – This analysis suggests that poorer health outcomes may be powerful predictors of consulting CAM practitioners, in some cases, amongst those who do not have access to the financial resources to pay for such treatment.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 486 - 486
1 Aug 2008
Pincus T Santos R Breen A Burton K Underwood M
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Objective: To improve the quality of prospective cohorts studying the transition from early stages of back pain to persistent problems, in order to allow researchers to improve the predictive quality, and pool data from multi-centre studies.

Summary of background: The progress from early stages of back pain to persistent problems is poorly understood, and only a fraction of the variance at outcome can be accounted for by current prospective cohorts. Standardization of a core set of factors would allow pooling and facilitate comparison between studies.

Method: Teams from 12 nations with expertise in clinical practice, prospective cohorts, epidemiology, social sciences, and health services were appointed.

The steering committee produced checklists of predictors and outcomes based on systematic reviews and a Delphi focus group. The international teams of experts coded each item for inclusion or exclusion, and recommended new items. This process was iterated twice to resolve disagreement between teams, and to receive scores for new items. The steering committee carried out a consensus synthesis and produced the final lists for predictors and outcome. Finally, the measurements for each factor were selected based on:

original systematic review

recommendations from existing systematic review

Recommendations from consensus statements and narrative reviews

consultation with independent experts.

Results: The checklist for predictors include information about demographics, clinical status, psychosocial status, work, and the first consultation for back pain. The recommendation for outcomes include pain, disability, return to work and sick leave, satisfaction, psychological factors, health care utilization and treatment over the follow up period.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 221 - 221
1 Jul 2008
Pincus T Foster N Vogel S Breen A Underwood M
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Background: Chiropractors, osteopaths and physiotherapists play key roles in the management of low back pain patients in the UK In our previous work we used mixed methods to investigate theor cognitions and attitudes to treating back pain. We developed and tested a scale, the Attitudes to Back Pain- Musculoskeletal Practitioners Scale, which includes both a personal and professional dimensional

Purpose: The purpose of this study was to investigate the differences between the attitudes of three professional groups: Chiropractors, Osteopaths and Physiotherapists.

Methods: A cross-sectional questionnaire survey was sent to 300 practitioners randomly selected from the registers of each profession. The returned questionnaires (N=465, response rate 61%), including the new ABS-mp and a questionnaire about personal and professional factors were analysed, using ANOVA, to compare the responses from the three groups.

Results: Physiotherapists tend to limit the number of treatment sessions offered to LBP patients. They work more clearly within a re-activation approach than their colleagues in the either of the other two professional groups. When practice setting (NHS versus private practice) was considered, the differences in personal interaction attitudes were unchanged but the differences in treatment orientation attitudes become less marked.

Conclusions: Aspects associated with practice settings, and especially those concerned with working within the NHS or privately impact on practitioners attitudes. There are also some professional differences, indicating that physiotherapists hold attitudes more closely in line with current guidelines.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 220 - 220
1 Jul 2008
Evans D Foster N Vogel S Breen A Underwood M Pincus T
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Background: The three professional groups of chiropractic, osteopathy and musculoskeletal physiotherapy are involved in the management of 15–20% of all people with low back pain (LBP) in the UK. Exploratory and descriptive research suggests that the management of non-specific LBP by some members of these groups does not follow best available evidence.

Purpose: To test the short-term effectiveness of a directly-posted, contextualised, printed educational package about the evidence-based management of acute LBP on changing UK chiropractors’, osteopaths’ and musculoskeletal physiotherapists’:

reported practice (based on a vignette of a patient with non-specific LBP)

beliefs and attitudes about LBP(using the HC-PAIRS, Rainville et al 1995)

Methods: A prospective, pragmatic randomised trial was designed to test the effectiveness of the printed educational package versus a no-intervention control. Questionnaires were posted to simple random samples of UK registered chiropractors (n=611), osteopaths (n=1368) and physiotherapists (n=1625). Intervention packages were sent to consenting practitioners in March 2004, and follow-up questionnaires were sent 6 months later.

Results: Good response rates to the baseline questionnaire were obtained, and most respondents were willing to participate in the RCT. Following exclusions based on criteria determined a priori, 1758/3380 (52.0%) consenting practitioners were recruited for the RCT: chiropractors 335/601 (55.7%), osteopaths 600/1335 (44.9%) and physiotherapists 823/1444 (57.0%). Overall response to the 6 month follow-up was 1557/1758 (88.6%): chiropractors 280/335 (83.6%), osteopaths 520/600 (86.7%) and physiotherapists 757/823 (92.0%).

Conclusions: Data analysis is now being carried out. The main trial results will be presented at the meeting.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 208 - 208
1 Apr 2005
Parsons S Harding G Underwood M Breen A Foster N Pincus T Vogel S
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Background – Chronic musculoskeletal pain (CMP) is a major health problem, for which patients consult a wide range of practitioners often with little success. This may be due to the sometimes different explanatory models for pain held by patients and practitioners. Gaining an understanding of these models may improve care. An area of conflict may be the identification and management of the psychological aspects of pain.

Purpose – To explore patients’ and practitioners’ beliefs and expectations of treatment for CMP, in relation to the identification and management of the psychological aspects to pain.

Method – In-depth qualitative interview study of 24 practitioners (osteopaths, chiropractors, physiotherapists and GPs) and 24 patients with CMP which explored their beliefs about causation and treatment of CMP. Maximum variety purposive samples of both groups were selected. All interviews were audio-taped and transcribed for analysis. Data was analysed using FRAMEWORK.

Results – Patients and practitioners believed that stress influenced pain perception, however some patients believed that stress could also cause pain. In terms of the consultation, practitioners felt pressure from patients to provide them with emotional / psychological support which on the whole they felt ill-equipped to provide. Patients operated with a physical model of illness and felt dismissed if practitioners focused too much attention on the psychological aspects of their pain.

Conclusion– Practitioners expressed confusion over what they were expected to provide patients in terms of psychological support. They also expressed a need for training in the management of behavioural / psychological aspects to pain. Patients may also require education to increase their awareness of the psychological aspects to their pain.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 207 - 207
1 Apr 2005
Pincus T Vogel S Santos R Breen A Foster N Underwood M
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Purpose and background: Practitioners’ beliefs about their professional role, their patients and the nature of back pain can impact on clinical decisions. These attitudes are likely to affect their choice to implement guidelines, whether they engage with their patients’ psychological problems, and their decisions about referral. We aimed to develop, test and explore the underlying dimensions of a new questionnaire, ‘The Attitudes to Back Pain Scale’ (ABS), in a specific group of clinicians, practitioners who specialise in musculoskeletal therapy: chiropractors, osteopaths and physiotherapists (COPs).

Methods and Results: We used a mixed methods study design. Using transcripts of interviews with 42 practitioners, we constructed 54 attitudinal statements, grouped theoretically into six sub-headings. We tested the validity of our categorization on 14 practitioners, who carried out a sorting task, including a rating of difficulty in cat-egorising each item. We sent the draft questionnaires to a large random sample of practitioners (300 COPs). 546 questionnaires were returned (61%). Exploratory and confirmatory factor analyses were performed on split samples of the dataset. Separate exploratory analyses were done for attitudes concerned with personal interaction (34 items) and attitudes about treatment orientation (18 items), producing six domains ‘Limitations on sessions’, ‘Psychological’, ‘System and Void’, ‘Clinical Limitations’, ‘Reactivation’, and ‘Biomedical’. Confirmatory analyses indicated that the model tested presented a good fit. Validity interviews revealed high agreement of categorisation and low levels of difficulty in categorising the items.

Conclusions: A new questionnaire for measuring clinicians’ attitudes towards back pain has been developed. Further work is required to assess the impact of these factors on practitioners’ behaviour and patient outcomes.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 208 - 208
1 Apr 2005
Parsons S Underwood M Breen A Foster N Pincus T Vogel S
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Background – Chronic musculoskeletal pain (CMP) is a major health problem treated by a wide range of health professionals. Complementary therapies are likely to become more readily available on the NHS. Therefore a greater understanding of current service use may be helpful in ensuring appropriate targeting of services in the future.

Purpose – To describe current service use for CMP in a UK representative population. To examine predictors of CMP use.

Methods – Population questionnaire survey to 4100 patients registered with 17 Medical Research Council General Practice Research Framework general practices. The questionnaire collected data on demographics, presence of pain, pain location and severity, health related quality of life (HRQOL), care seeking and beliefs about pain. Univariate and multivariate analyses was undertaken to examine predictors of care seeking.

Results – Response rate of 61% of whom 47% reported CMP use. 77% consulted for their CMP; 60% mainstream medicine only, 17% mainstream and / or complementary and 22% no-one.

Patients who consulted complementary practitioners were more likely to be female, to be psychologically distressed, to work, to have left school aged over 16 and to have severe pain (p< 0.05 in all cases). Working was independently associated with consulting a complementary practitioner (Exp (B) = 2.0, p=0.00)

Conclusion – Complementary therapies are currently only available to those patients who can afford them. If such therapies become available on the NHS it may be important to provide patients and health professionals with appropriate information to inform their choices about these care options.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 208 - 209
1 Apr 2005
Evans D Foster N Vogel S Breen A Underwood M Pincus T
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Background The three professional groups of chiropractic, osteopathy and musculoskeletal physiotherapy are involved in the management of 15–20% of people with low back pain (LBP) in the UK (CSAG 1994). Exploratory and descriptive research suggests that the management of non-specific low back pain (LBP) by some members of these groups does not follow best available evidence (RCGP 1999).

Purpose To test the short-term effectiveness (at 6 months) of a directly-posted, contextualised, printed educational package about the evidence-based management of acute back pain on changing UK chiropractors’, osteopaths’ and musculoskeletal physiotherapists’:

1) beliefs and attitudes about LBP

2) reported practice (using a clinical vignette)

Methods A prospective, pragmatic randomised trial was designed to test the effectiveness of the printed educational package versus a no-intervention control. MREC approval was gained and a questionnaire was developed and piloted (n=150). Information was gathered on practitioners’ demographics, their beliefs about LBP (using the HC-PAIRS, Rainville et al 1995) and reported practice based on a vignette of a patient with non-specific LBP (adapted from Bombardier et al 1995, Buchbinder 2001).

A total of 3602 questionnaires were posted to simple random samples of UK registered chiropractors (n=611), osteopaths (n=1367) and physiotherapists (n=1624). Intervention packages were sent to consenting practitioners in March 2004, and the follow-up is planned for September 2004.

Results Good response rates to the baseline questionnaire were obtained, and most respondents were willing to participate in the RCT. Following exclusions based on a priori criteria, 1773/3402 (52.1%) participants were recruited for the RCT: chiropractors 335/604 (55.4%), osteopaths 600/1338 (44.8%) and physiotherapists 838/1460 (57.4%). The RCT methodology and some baseline data will be presented.

Conclusions It is possible to recruit large numbers of healthcare practitioners, within and outside the NHS, to RCTs conducted by post. Whilst the results will be specific to these three professional groups in the UK, this study is believed to be the largest RCT of printed, evidence-based educational material in healthcare, to incorporate a no-intervention control group.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 207 - 207
1 Apr 2005
Parsons S Underwood M Breen A Foster N Pincus T Vogel S
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Background: Chronic musculoskeletal pain (CMP) is a major health problem for the individual and the NHS. It is important to examine the prevalence of and factors associated with it, to identify unmet need and inform the development of interventions.

Purpose: To describe the prevalence of CMP in a community based sample, overall and by location; To describe the factors associated with presence of CMP.

Methods: Population questionnaire survey to 4100 patients registered with 17 Medical Research Council General Practice Research Framework practices. We collected questionnaire data on demographics, presence and location of pain, pain severity, health related quality of life, care seeking and beliefs about pain. We then did univariate and multivariate analyses to identify factors associated with CMP.

Results: Survey response rate was 61% (2509/4100); mean age 52 years (range 18–101); 56% female. CMP prevalence was 47%. One month period prevalence by area was; Lower back 23%; Knee 19%%; Shoulder 16%; Hip/thigh 14% and Upper back 6%. The majority of sufferers consulted their GP (61%), but a large minority (21%) consulted no-one. Factors associated with presence of CMP were being older, leaving school aged 16 or less, not working, having poorer quality of life and experiencing psychological distress (P< 0.05). In a multivariate analysis no factors were independently associated with presence of CMP.

Conclusion: Results demonstrate the significant burden CMP presents in the community and the need to focus interventions on those individuals who may be more likely to suffer. It may be particularly important to consider the needs of those who have not consulted anyone.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_I | Pages 39 - 39
1 Mar 2005
Evans D Foster N Vogel S Breen A
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Background & Objectives: The physical therapy professions (musculoskeletal physiotherapy, osteopathy and chiropractic) are involved in the management of low back pain (LBP) in approximately 15–20% of all cases in the UK. LBP accounts for between 50% and 67% of the workload of this group. Initiatives to implement evidence-based practice (EBP) in the UK have included the development of national multidisciplinary guidelines for acute LBP, the target audience of which include all three physical therapy professions.

The objective of this study was to explore and identify perceptions, attitudes and beliefs held by practitioners from these three professional groups about their approaches to the care of LBP patients.

Methods & Results: An exploratory study was used to investigate beliefs and attitudes of practitioners, concerning factors that potentially influence practice. Particular attention was given to practitioners’ thoughts on the opportunities and threats of taking an EBP approach to LBP management, and identifying other factors that influence their clinical behaviour with LBP patients. Following ethical approval and informed consent, five focus groups were conducted with members of the physical therapy professions. Audio recordings of each focus group were made, and subsequently transcribed verbatim. Transcript data were analysed in line with a grounded theory approach to produce relevant themes.

Preliminary categories of themes that emerged were: Evidence; Perceived Knowledge; Personality Characteristics; Professional Identity; The Patient; and Motivation. Of particular interest, practitioners seem to have mixed opinions with regard to basing their practice on evidence from external research.

Conclusions: Practitioners’ views of EBP in LBP management are diverse and it cannot be presumed that all practitioners view EBP as desirable. They seem to have mixed opinions with regard to basing their practice on evidence from external research. Practitioner behaviour, and thus the implementation of EBP may relate to practitioners’ beliefs and attitudes.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_I | Pages 35 - 35
1 Mar 2005
Breen A Muggleton J Mellor F Morris A Eisenstein S Thomas L
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Background: Intervertebral motion is often assumed to be altered with back pain, however, the patterns are inaccessible to measurement in live subjects. A method for digitally tracking and analysing fluoroscopic images of the vertebrae of subjects who are undergoing standardised passive motion has recently been brought into clinical use for the assessment of surgical fusions. We have studied the differences between the behaviour of spinal linkages in subjects who are asymptomatic, and those who have had fusion operations. This paper describes the reliability, ranges and qualitative features of intervertebral motion patterns in 27 asymptomatic subjects and 3 fusion patients.

Methods and results: Thirty asymptomatic male volunteer subjects aged 19–40, underwent 2 –20 second sessions of fluoroscopic screening during 80 degrees of lumbar spine bending within 20 minutes of each other. Intervertebral sidebending motion from L2–5 was measured in 27 subjects whose images were judged suitable for tracking. Approximately 120 digitised images throughout each motion sequence were analysed 5 times by 2 blinded observers for intervertebral range and each result averaged. The intra-subject biological error (RMS), for range of intervertebral motion was 2.75° for Observer1 and 2.91° for Observer 2. The interobserver error for tracking the same screenings was 1.86° (RMS). At almost all levels, these motion patterns were remarkably regular.

Four male patients aged 33, 44, 45 and 52 years, who had undergone different spinal stabilisation procedures consisting of flexible stabilisation (DNESYS), posterior instrumented fusion, and anterior interbody fusion with facet fixation were investigated. Images were acquired and analysed in the same way except that a larger number of images (500 per screening) was utilised in each case. Four operated levels and 2 adjacent levels were analysed. All motion patterns were easily distinguishable from those of the normal subjects. The PLIF and DYNESYS stabilisations demonstrated no motion at the instrumented levels. The anterior inter-body fusion-transfacet fixation patient was shown to have developed a pseudarthrosis.

Conclusions: Detailed lumbar intervertebral bending patterns in asymptomatic subjects were distinguishable from the fused and adjacent-to fused segments in operated patients. Results suggest that there is sufficient reliability in the method to evaluate lumbar intersegmental ranges and motion patterns for fusion assessment.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 239 - 239
1 Mar 2003
Parsons S Breen A Foster N Harding G Pincus T Underwood M Vogel S
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Background: A wide variety of practitioners with different belief systems and approaches treat chronic musculoskeletal pain. In trials of treatments for musculoskeletal pain the focus has tended to be on outcome rather than on understanding the process of care of these treatments. Gaining greater understanding of the process of care in consultations for chronic musculoskeletal pain may shed light on ways to improve patient care, as despite the range of options available many patients are still dissatisfied with their treatment.

Aim: To undertake a systematic review to explore how the beliefs and expectations of patients with chronic musculoskeletal pain and their treating primary and community care practitioners / therapists influence the process of care

Method: A comprehensive search strategy was developed. Databases including MEDLINE, PSYCHINFO, AMED, and MANTIS were searched by two members of the review group working independently. Two members of the group again working independently screened the title and abstract of each reference retrieved for inclusion. Studies were included if they Reported original research

Explored patient’s or practitioners; beliefs and expectations, or both.

Studied patients with chronic musculoskeletal pain, which does not have a known systemic, inflammatory or malignant origin treated in primary or community care.

The full review group resolved disagreements. Full text articles meeting the inclusion criteria will be obtained and coded further into non-randomised studies, randomised studies and qualitative studies. Data abstraction forms will be developed for each type of study. Data abstraction will be undertaken by two members of the group working independently.

Results: 12, 667 articles were identified from the searches of bibliographic databases. At the present time 10 papers have been identified for potential inclusion in the review. The number of full papers to be considered for the review will be reported in this presentation along with the methods for data abstraction and synthesis. This study is ongoing.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 243 - 243
1 Mar 2003
Breen A Muggleton J Mellor F Morris A Eisenstein S Thomas L
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Background: The prospect of a second operative procedure following an apparently unsuccessful spinal fusion is an unwelcome one. Since 1987, we have worked to develop an objective method of measuring the motion between vertebrae from fluoroscopic images. Successive versions have been evaluated for their reliability and validity. However, only the current one combines sufficiently reduced operator interaction with acceptable error limitation to be operationally useful as a tool for reporting findings about graft integrity for spinal surgeons. The current work brings this to an advanced prototype stage.

Methods and results: The measurement of lumbar intervertebral coronal and saggital plane motion in vivo using this technique is in 3 stages: Fluoroscopic screening of patients lying on a passive motion table Co-ordinated real-time digital acquisition of the intensifier images.

Registration of the images of each vertebra by templates which are automatically tracked and whose output is converted to inter-vertebral kinematic parameters and averaged for display and reporting.

Results are currently displayed as inter-vertebral angles throughout the motion that indicate whether or not solid fusion has been achieved. The Instrument Measurement Error is quantifiable and will vary with image quality, but can be improved by averaging. The technology is applicable to any imaging system of sufficient speed and resolution and may, for example, be used with MR in the future.

Conclusions: An advanced prototype version of this device is now approaching readiness for service as a routine procedure for use by specially trained radiographers. Its limitations will be determined mainly by the quality of the intensifier images. This can be expected, in the future, to benefit from yet further advances in the technology.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_I | Pages 94 - 94
1 Mar 2002
Foster N Underwood M Pincus T Breen A Harding G Vogel S
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The traditional biomedical model of managing musculoskeletal problems, such as low back pain (LBP), tends to be pathology driven, in which the aim is to locate an objectively identified disturbance. Appropriate treatment is conceptualised as a physical intervention that will compensate for or correct the identified disturbance. There is growing appreciation of the need to consider other factors, e.g. the meaning of the problem to the patient and professional, his/her experiences, cognitions, motivations and preferences. Improving the understanding about the beliefs and expectations of patients and health professionals is fundamental, since a better understanding of these factors, and any mismatch between professionals and patients, will facilitate improved management.

A multidisciplinary group of researchers (chiropractor, GP, osteopath, physiotherapist, psychologist, sociologist) have developed a collaborative research programme to investigate the decision-making processes in the care of patients with musculoskeletal pain. The programme uses mixed methods, including systematic reviews, survey research, focus groups and semi-structured interviews with patients and practitioners.

Three studies have already started: patient and health professional beliefs and expectations for the causes and treatment of chronic musculoskeletal pain. 1) Funded by the ARC, the purpose is to develop an understanding of the relationships between the different, professional and lay, theoretical frameworks used to diagnose and treat chronic musculoskeletal pain, and how these affect care. 2) Clinicians cognitions in apparently ineffective treatment of low back pain: funded by the ESRC, the purpose is to identify the reasons clinicians continue to treat LBP in the absence of improvement. Research on risk factors for the transition from acute to chronic LBP has concentrated on patient characteristics (psychological and social). It is possible that clinicians’ behaviour, advice and even treatment contribute to maintaining the problem indirectly. 3) Overcoming barriers to evidence-based practice (EBP) in LBP management in the physical therapy professions; funded by the Department of Physiotherapy Studies, Keele University, this study aims to explore the perceptions of physiotherapists, chiropractors and osteopaths, about the opportunities and threats of taking an EBP approach to LBP management and identify methods by which implementation of evidence can be facilitated.

This collaboration is the first of its kind and was developed through shared interests in the decision-making processes in the healthcare of people with musculoskeletal pain. We are keen to share the ideas and work in progress with the wider musculoskeletal pain research community.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_I | Pages - 94
1 Mar 2002
Breen A Muggleton J Kondracki M Wright J Morris A
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This study compared the effect of manipulation with a period of normal activity on the range of intervertebral sidebending.

Thirty asymptomatic male volunteers were randomised to treatment or control groups. All were subjected to low-dose X-ray screening through 80° of passive lumbar spine side-bending. Motion sequences were digitised at a 5Hz sampling rate. The treatment group (n=16) had rotary manipulation to each lumbar linkage, followed by normal activity. The control group (n=14) had normal activity only. Both groups were then re-screened. Each vertebral pair was tracked and intervertebral rotation throughout the motion measured. Three subjects were analysed 10 times for reliability and all intervertebral motion was tracked twice.

Twenty-one manipulated linkages and 10 controls met the reliability criteria. For non-manipulated segments the mean range at first screening was 14.2° (SD 1.39) and manipulated segments 12.8° (SD 3.81). The range of the non-manipulated segments increased by +0.9o and the manipulated segments by +0.4°.

The change in manipulated segments was negligible and similar to controls, although the instrument can be sufficiently reliable to measure a 2° difference. The technique is sufficiently robust to determine if spinal manipulation changes these ranges in selected patients.