Aims. There is evidence that morbidly
Aims. The aim of this study was to investigate the global and local impact of fat on bone in
Aims. The purpose of this study was to assess total knee arthroplasty (TKA) volume and rates of early complications in morbidly
Aims. Access to total knee arthroplasty (TKA) is sometimes restricted for patients with severe
Aims.
Aims. It has been shown that the preoperative modification of risk factors associated with
Aims. The aim of this study was to assess the influence of
Aims. The purpose of our study is to summarise the current scientific
findings regarding the impact of
Aims. Rates of readmission and reoperation following primary total knee arthroplasty (TKA) are under scrutiny due to new payment models, which penalize these negative outcomes. Some risk factors are more modifiable than others, and some conditions considered modifiable such as
Aims. The aim of this study was to observe the implications of withholding total joint arthroplasty (TJA) in morbidly
Aims. This study investigated the influence of body mass index (BMI)
on patients’ function and quality of life ten years after total
knee arthroplasty (TKA). Patients and Methods. A total of 126 patients who underwent unilateral TKA in 2006
were prospectively included in this retrospective study. They were
categorized into two groups based on BMI: < 30 kg/m. 2. (control)
and ≥ 30 kg/m. 2. (obese). Functional outcome was assessed
using the Knee Society Function Score (KSFS), Knee Society Knee
Score (KSKS), and Oxford Knee Score (OKS). Quality of life was assessed
using the Physical (PCS) and Mental Component Scores (MCS) of the 36-Item
Short-Form Health Survey. Results. Patients in the
Aims. The aim of this study was to utilize a national paediatric inpatient database to determine whether
Given the growing prevalence of
Objectives. The objective of this study was to investigate the association of four single-nucleotide polymorphisms (SNPs) of the cannabinoid receptor 2 (CNR2) gene, gene-obesity interaction, and haplotype combination with osteoporosis (OP) susceptibility. Methods. Chinese patients with OP were recruited between March 2011 and December 2015 from our hospital. In this study, a total of 1267 post-menopausal female patients (631 OP patients and 636 control patients) were selected. The mean age of all subjects was 69.2 years (sd 15.8). A generalized multifactor dimensionality reduction (GMDR) model and logistic regression model were used to examine the interaction between SNP and
A total of 445 consecutive primary total knee
replacements (TKRs) were followed up prospectively at six and 18 months
and three, six and nine years. Patients were divided into two groups:
non-obese (body mass index (BMI) <
30 kg/m. 2. ) and obese
(BMI ≥ 30 kg/m. 2. ). The
Introduction: This observational study assessed the influence of
This study evaluated whether
Introduction. The purpose of this study is to estimate the cost-effectiveness of performing total hip arthroplasty (THA) versus nonoperative management (NM) in non-obese (BMI 18.5–24.9), overweight (25–29.9),
Total Knee Arthroplasty (TKA) in
Background. While tranexamic acid (TXA) has been well shown to reduce blood loss after joint replacement surgery, little is known regarding its effectiveness in
The significance of weight in the indications
for unicompartmental knee replacement (UKR) is unclear. Our hypothesis was
that weight does not affect the long-term rate of survival of UKRs. We undertook a retrospective study of 212 UKRs at a mean follow-up
of 12 years (7 to 22). The patients were distributed according to
body mass index (BMI; <
The ten-year rates of survival were similar in the two weight
subgroups (≥ 82 kg: 93.5% (95% confidence interval (CI) 66.5 to
96.3); <
82 kg: 92.5% (95% CI 82.5 to 94.1)) and also in the
two BMI subgroups (≥ 30 kg/m2: 92% (95% CI 82.5 to 95.3);
<
30 kg/m2: 94% (95% CI 78.4 to 95.9)). Multimodal
regression analysis revealed that weight plays a part in reducing
the risk of revision with a relative risk of 0.387, although this
did not reach statistical significance (p = 0.662). The results
relating weight and BMI to the clinical outcome were not statistically
significant. Thus, this study confirms that weight does not influence
the long-term rate of survival of UKR. Cite this article:
The aim of this study was to examine the incidence of
Spinal surgery in
Due to shorter hospital stays and faster patient rehabilitation Unicompartmental Knee Replacements (UKR) are now considered more cost effective than Total Knee Joint Replacements (TKJR).
Osteoarthritis (OA) of the hip is the most common indication for total hip replacement (THR).
To determine the risk of total knee replacement (TKR) for primary osteoarthritis (OA) associated with overweight/
Literature has suggested that
Background.
Abstract. Objectives.
Aims. We studied the outcomes of hip and knee arthroplasties in a high-volume arthroplasty centre to determine if patients with morbid
Direct anterior approach (DAA) arthroplasty has generated great interest because of its minimally invasive and muscle sparing nature.
To describe the longitudinal trends in patients with
In a recent study, 54.5% of patients reporting to arthroplasty clinics in the US were
Over the last decade, the number of total knee arthroplasty (TKA) has risen over 125%. Numerous studies have established a relationship between
We hypothesised that diet-induced
Osteoarthritis is one of the major causes of immobility. Most commonly, osteoarthritis manifests at the knee joint. Prevalence of knee osteoarthritis (KNOA) increases with age. Another important risk factor for KNOA is
Introduction. Previous research has indicated that preoperative modification of risk factors associated with
Aim. The aim of this study is to evaluate if
Introduction. Rates of readmission and reoperation following primary total knee arthroplasty (TKA) are under scrutiny due to new payment models, which penalize these negative outcomes. Many prior studies have demonstrated the risk of perioperative complications among patients with
The purpose of this population-based study was to determine the association between morbid
Introduction. Perioperative optimization efforts have improved outcomes following primary total knee arthroplasty (TKA). However, morbidly
As the American population ages and a trend toward performing total hip arthroplasty (THA) in younger patients continues, the number of Americans undergoing THA is projected to increase over time. The advent of the bundled payment system combined with the current medical utilization climate has placed considerable pressure on surgeons to produce excellent results with early functional recovery and short hospital stays. The US
A prospective, multi-centre study was carried out on 1421 total hip replacements between January 1999 and July 2007 to examine if
Abstract. Aims. The association between body mass index (BMI) and venous thromboembolism (VTE) is well studied, but remains unclear in the literature. We aimed to determine whether morbid
Background.
Purpose.
Introduction. Given the association of osteoarthritis with
In the USA, 34.9% of adults are currently
The US
Objectives. Given the function of adiponectin (ADIPOQ) on the inflammatory condition of
Introduction. At a time when many surgeons are reluctant to perform a unilateral TKA in the
We carried out a prospective, continuous study on 529 patients who underwent primary total knee replacement between January 2006 and December 2007 at a major teaching hospital. The aim was to investigate weight change and the functional and clinical outcome in non-obese and
Aim.
There has been considerable discussion as to the influence of
Aims. Mendelian randomization (MR) is considered to overcome the bias of observational studies, but there is no current meta-analysis of MR studies on rheumatoid arthritis (RA). The purpose of this study was to summarize the relationship between potential pathogenic factors and RA risk based on existing MR studies. Methods. PubMed, Web of Science, and Embase were searched for MR studies on influencing factors in relation to RA up to October 2022. Meta-analyses of MR studies assessing correlations between various potential pathogenic factors and RA were conducted. Random-effect and fixed-effect models were used to synthesize the odds ratios of various pathogenic factors and RA. The quality of the study was assessed using the Strengthening the Reporting of Observational Studies in Epidemiology using Mendelian Randomization (STROBE-MR) guidelines. Results. A total of 517 potentially relevant articles were screened, 35 studies were included in the systematic review, and 19 studies were eligible to be included in the meta-analysis. Pooled estimates of 19 included studies (causality between 15 different risk factors and RA) revealed that
BACKGROUND. The
We evaluated 535 consecutive primary cementless total knee replacements (TKR). The mean follow-up was 9.2 years (0.3 to 12.9) and information on implant survival was available for all patients. Patients were divided into two groups: 153
We evaluated the outcome of primary total hip replacement (THR) in 3290 patients with the primary diagnosis of osteoarthritis at a minimum follow-up of two years. They were stratified into categories of body mass index (BMI) based on the World Health Organisation classification of
The aim of this study was to determine whether
obesity affects pain, surgical and functional outcomes following lumbar
spinal fusion for low back pain (LBP). A systematic literature review and meta-analysis was made of
those studies that compared the outcome of lumbar spinal fusion
for LBP in
The outcome of total hip replacement (THR) is potentially affected by the body mass index (BMI) of the patient. We studied the outcome of 2026 consecutive primary cementless THRs performed for osteoarthritis. The mean follow-up was 6.3 years (0 to 11.71) and no patient was lost to follow-up for survival analysis. The patients were divided into two groups according to their BMI as follows: non-obese (BMI <
30 kg/m. 2. ) and
We compared 55 consecutive total hip replacements performed on 53 morbidly
Abstract. INTRODUCTION. The most frequent mode of aseptic failure of primary total knee replacements is tibial baseplate loosening. This is influenced by stresses across the implant-bone interface which can be increased in
We studied a consecutive series of 285 uncemented total hip replacements in 260 patients using the Taperloc femoral component and the T-Tap acetabular component. The outcome of every hip was determined in both living and deceased patients. A complete clinical and radiological follow-up was obtained for 209 hips in 188 living patients, followed for a mean of 14.5 years (10 to 18.9). They were divided into two groups,
Introduction. Rapid recovery protocols after joint replacement have been implemented widely to decrease hospital length of stay (LOS). Minimally-invasive total knee arthroplasty (MIS-TKA) may facilitate rapid recovery for patients. Increased complications and LOS have been documented in morbidly
Objectives. Metabolic syndrome and low-grade systemic inflammation are associated with knee osteoarthritis (OA), but the relationships between these factors and OA in other synovial joints are unclear. The aim of this study was to determine if a high-fat/high-sucrose (HFS) diet results in OA-like joint damage in the shoulders, knees, and hips of rats after induction of
Purpose. To investigate the effect of
Introduction. Published literature that examined pre-operative Body Mass Index (BMI) with Total Knee Arthroplasty (TKA) outcomes have shown conflicting data. Some show that higher BMI and is associated with poorer post-TKA function and HRQoL outcomes, but not others. The aim of our analyses is to identify the relationship of pre-operative
Background. Tranexamic acid (TXA) is a lysine analog that has been shown to reduce intra-operative blood loss in total joint replacements. Effect of TXA in morbid
Abstract. Introduction. Surgery in patients with high body mass index (BMI) is more technically challenging and associated with increased complications post-operatively. Inferior clinical and functional mid-term results for high BMI patients undergoing high tibial osteotomy (HTO) relative to normal weight patients have been reported. This study discusses the clinical, radiological and functional outcomes of HTO surgery in patients with a high BMI. Method. This is a retrospective study on patients undergoing HTO surgery using the Tomofix anatomical MHT plate between 2017 and 2022, with follow-up period of up to 5 years. The cohort was divided: non-obese (BMI <30 kg/m2) and
Introduction: The prevalence of
Introduction. Morbid
Purpose. To update recent findings about the relationship between
The purpose of this study was to evaluate the effect of body mass index (BMI) on patients undergoing primary total knee arthroplasty for osteoarthritis. Data was collected on 664 patients at 4 centres all of whom received a Depuy PFC Sigma prosthesis. Data collected included patient demographics, Oxford Knee Score (OKS), American Knee Society Score, SF-12, complications of surgery and the need for revision. 14% of patients had a BMI<25, 35% were overweight (BMI-25–30), 32% suffered from Grade 1
Introduction. The direct anterior (DA) approach for total hip arthroplasty has demonstrated successful short term outcomes. However, debate remains about which patients are candidates fo this approach. To our knowledge, there are no studies which specifically investigate short-term outcomes in
Introduction. Reported data on impact of
Purpose: The aim of this study was to evaluate the rate of surgical site infection (SSI) in all patients undergoing a primary total knee arthroplasty (TKA) and to audit the outcomes for those who were
The recent NICE guidelines on management of osteoarthritis outline weight loss as first line treatment in degenerative joint disease in the
Introduction. Early complication post total knee replacement reported to be higher in
Introduction. It is widely accepted that intra-articular graft reconstruction with correct placement stands the greatest chance of abolishing symptomatic instability secondary to anterior cruciate ligament (ACL) deficiency. It is estimated that at least 100,000 ACL reconstructions are performed a year in the USA, where approximately 30% of the population are currently clinically
Total knee arthroplasty is a successful procedure that reduces knee pain and improves function in most patients with knee osteoarthritis. Patient dissatisfaction however remains high, and along with implant longevity, may be affected by component positioning. Surgery in
Many orthopaedic surgeons believe that
What are the data on