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The Bone & Joint Journal
Vol. 95-B, Issue 5 | Pages 673 - 677
1 May 2013
Menakaya CU Pennington N Muthukumar N Joel J Ramirez Jimenez AJ Shaw CJ Mohsen A

This paper reports the cost of outpatient venous thromboembolism (VTE) prophylaxis following 388 injuries of the lower limb requiring immobilisation in our institution, from a total of 7408 new patients presenting between May and November 2011. Prophylaxis was by either self-administered subcutaneous dalteparin (n = 128) or oral dabigatran (n = 260). The mean duration of prophylaxis per patient was 46 days (6 to 168). The total cost (pay and non-pay) for prophylaxis with dalteparin was £107.54 and with dabigatran was £143.99. However, five patients in the dalteparin group required nurse administration (£23 per home visit), increasing the cost of dalteparin to £1142.54 per patient. The annual cost of VTE prophylaxis in a busy trauma clinic treating 12 700 new patients (2010/11), would be £92 526.33 in the context of an income for trauma of £1.82 million, which represents 5.3% of the outpatient tariff.

Outpatient prophylaxis in a busy trauma clinic is achievable and affordable in the context of the clinical and financial risks involved.

Cite this article: Bone Joint J 2013;95-B:673–7.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_7 | Pages 20 - 20
1 Feb 2013
Mallick A Muthukumar N Sharma H
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Introduction

Restoration of mechanical axis is one of the main aims during Total Knee Arthroplasty (TKA) surgery. Treatment of osteoarthritis (OA) of the knee with extra-articular deformity either in femur or in tibia poses a technical challenge in achieving this aim. Insufficient correction of axis is associated with poor clinical outcome of total knee arthroplasty (TKA). Extra-articular deformity can either be addressed with compensatory intra-articular bone resection at the time of TKA or correctional osteotomy prior to or at the time of TKA.

Patients & Methods & Results

We present our experience of treating 7 patients with knee arthritis (9 knees) and significant extra-articular deformity.

Two patients had OA knee with severe valgus deformity in tibia from recurrent stress fractures. One was treated with one-stage corrective osteotomy and long stem modular TKA. The other had deformity correction with two level tibial osteotomy with intramedullary nail and modular long stem TKA later. Both required tibial tubercle osteotomy during TKA.

Two patients with bilateral OA knees and significant varus deformity had sequential deformity correction with Taylor Spatial Frame (TSF) followed by TKA on one side and a single stage intra-articular correction during TKA on the other.

Three patients with knee OA and associated deformity (femoral - two pt., tibia one pt.) had symptom resolution with just correction of malaligment with Taylor Spatial Frame (TSF) and did not require TKA.


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 5 | Pages 690 - 697
1 May 2012
Khan MA Hossain FS Dashti Z Muthukumar N

The aim of this study was to examine the rates and potential risk factors for 28-day re-admission following a fracture of the hip at a high-volume tertiary care hospital. We retrospectively reviewed 467 consecutive patients with a fracture of the hip treated in the course of one year. Causes and risk factors for unplanned 28-day re-admissions were examined using univariate and multivariate analysis, including the difference in one-year mortality. A total of 55 patients (11.8%) were re-admitted within 28 days of discharge. The most common causes were pneumonia in 15 patients (27.3%), dehydration and renal dysfunction in ten (18.2%) and deteriorating mobility in ten (18.2%). A moderate correlation was found between chest infection during the initial admission and subsequent re-admission with pneumonia (r = 0.44, p < 0.001). A significantly higher mortality rate at one year was seen in the re-admission group (41.8% (23 of 55) vs 18.7% (77 of 412), p < 0.001). Logistic regression analysis identified advancing age, admission source, and the comorbidities of diabetes and neurological disorders as the strongest predictors for re-admission. Early re-admission following hip fracture surgery is predominantly due to medical causes and is associated with higher one-year mortality. The risk factors for re-admission can have implications for performance-based pay initiatives in the NHS. Multidisciplinary management in reducing post-operative active clinical problems may reduce early re-admission.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 328 - 328
1 May 2010
Sidhom S Al-Lami M Sturdee S Anderson A Muthukumar N Hughes V Bennett C London N
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Aim: To assess the safety and efficacy of a mini-incision surgical (MIS) approach to knee arthroplasty (TKA) compared to a traditional standard approach.

Background: TKA through less invasive approaches have become increasingly popular in recent years. These range from smaller skin incisions to the ‘quadriceps-sparing’ procedures. Claims of improved recovery time and other clinical/economic advantages have been tempered by concerns about the safety of such procedures. This study was designed to evaluate any potential advantages of a specific approach (MIS) whilst studying peri-operative, radiological and outcome data to examine procedural safety.

Patients and Methods: 80 patients undergoing TKA were randomised to a standard or MIS (mini-midvastus) approach. The latter involved patella subluxation, rather than eversion. The operative, anaesthetic and post-operative treatments were standardised including rehabilitation protocols. Strict discharge criteria were established and independently verified and patients were discharged directly to their homes capable of independent care. Specifically the study evaluated patient demographics, operative time, blood loss and hospital stay. Outcome data including Knee Society Scores, Oxford Knee Scores and SF36 were recorded regularly in the early recovery period and up to 1 year post-operatively. Independent radiological review of implant positioning and alignment was obtained.

Results: There were no significant differences in operative time, blood loss, or other intra-operative data. Accelerated discharge was achieved in both groups (compared to historic data), however the length of stay (LOS) was significantly shorter in the MIS patients (mean – 3.5 days compared with 4.4 days in the standard patients). There was no statistical difference in clinical outcome analyses between the groups.

Discussion: Less invasive approaches to TKA have been reported over recent years but most studies have been anecdotal comparing patient recovery with historic controls which potentially can exaggerate clinical and economic benefits. Concerns have also been raised regarding the safety of these modified procedures. This study demonstrates a reduction in hospital stay and recovery in all patients as a result of accelerated rehabilitation. The MIS patients benefited from an additional significant reduction length of stay compared to controls with no evidence of compromise in terms of safety or efficacy.

Conclusions: This study has demonstrated the safety of the MIS mini-midvastus approach and a clear reduction in hospital length of stay. MIS surgery can offer substantial clinical and economic benefits but procedures must be closely evaluated to ensure equivalent or enhanced outcomes are achieved.