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Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_13 | Pages 11 - 11
17 Jun 2024
Lewis T Ferreira G Nunes G Ray R
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Background

Infiltration is considered the first treatment option for symptomatic Morton's neuroma and can be performed with various medications. The aim of this study was to compare the effects of hyaluronic acid infiltration versus corticosteroid injection in the treatment of Morton's neuroma.

Methods

A randomised clinical trial was conducted with 46 patients (50 feet) diagnosed with Morton's neuroma. After randomisation, the control group (CG) received three injections (one per week) of triamcinolone (Triancil®) guided by ultrasound, while the study group (SG) received three applications of hyaluronic acid (Osteonil Plus®). Patients were followed up for six months after the intervention. The primary outcome measure used was the Visual Pain Analog Scale (VAS). Secondary endpoints included patient-reported outcome measures using the American Orthopaedic Foot & Ankle Society (AOFAS) score and complications.


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_11 | Pages 23 - 23
4 Jun 2024
Trowbridge S Lewis T Shehata R Lau B Lyle S Ray R
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Background

Hallux rigidus is a common condition characterised by first metatarsophalangeal joint (MTPJ) degeneration, pain and limited range of motion (ROM). The gold standard surgical treatment is arthrodesis, providing good pain relief but sacrifices ROM. Recently the Cartiva synthetic cartilage implant (SCI) has been utilised as an interpositional arthroplasty, aiming to reduce pain whilst preserving range of motion. Current evidence for Cartiva SCI is largely based on a single cohort with mixed outcomes. We sought to evaluate the clinical outcomes of Cartiva SCI compared to arthrodesis undertaken in our centre.

Methods

Retrospective review of patients undergoing Cartiva SCI or arthrodesis for treating hallux rigidus was conducted. Preoperative arthritis was radiographically graded using the Vanore classification. Patient reported outcomes (PROMs) were assessed using EuroQol 5-dimension score (EQ-5D-5L) and Manchester-Oxford Foot Questionnaire (MOXFQ).


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_11 | Pages 21 - 21
4 Jun 2024
Lewis T Ray R Gordon D
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Background

The effect of hallux valgus (HV) on health-related quality of life (HRQOL) and the relationship between radiographic severity of deformity and patient reported outcome measures (PROMs) is poorly understood. The aim of this study was to compare the HRQOL of female patients with HV to the UK population. The secondary aim was to assess the correlation between PROMs, including HRQOL, with radiographic severity of deformity.

Methods

Weight bearing radiographic data (hallux valgus (HVA) angle; intermetatarsal (IM) angle) were measured in consecutive female patients presenting with HV. Each patient prospectively completed the Euroqol EQ-5D-5L questionnaire (EQ-5D), Visual Analogue Scale for Pain (VAS-Pain) and Manchester Oxford Foot Questionnaire (MOXFQ). Data were stratified into age ranges and compared with an EQ-5D United Kingdom general population reference dataset. Pearson R correlation values were calculated for the PROMs and radiographic deformity.


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_11 | Pages 20 - 20
4 Jun 2024
Lewis T Robinson PW Ray R Dearden PM Goff TA Watt C Lam P
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Background

Recent large studies of third-generation minimally invasive hallux valgus surgery (MIS) have demonstrated significant improvement in clinical and radiological outcomes. It remains unknown whether these clinical and radiological outcomes are maintained in the medium to long-term. The aim of this study was to investigate the five-year clinical and radiological outcomes following third-generation MIS hallux valgus surgery.

Methods

A retrospective observational single surgeon case series of consecutive patients undergoing primary isolated third-generation percutaneous Chevron and Akin osteotomies (PECA) for hallux valgus with a minimum 60 month clinical and radiographic follow up. Primary outcome was radiographic assessment of the hallux valgus angle (HVA) and intermetatarsal angle (IMA) pre-operatively, 6 months and ≥60 months following PECA. Secondary outcomes included the Manchester-Oxford Foot Questionnaire, patient satisfaction, Euroqol-5D Visual Analogue Scale and Visual Analogue Scale for Pain.


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_10 | Pages 6 - 6
23 May 2024
Lewis T Ray R Gordon D
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Background

There are many different procedures described for the correction of hallux valgus deformity. Minimally invasive surgery has become increasingly popular, with clinical and radiological outcomes comparable to traditional open osteotomy approaches. There is increasing interest in hallux valgus deformity correction using third-generation minimally invasive chevron akin osteotomy (MICA) technique.

Objective

To assess the radiographic correction and 2 year clinical outcomes of third-generation MICA using validated outcome measures.


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_18 | Pages 15 - 15
1 Dec 2023
Lewis T Franklin S Vignaraja V Ray R
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Introduction

Chronic ankle instability is a common condition that can be effectively treated with arthroscopic lateral ankle ligament reconstruction to restore ankle stability and function. The aim of this study was to assess the functional outcomes of arthroscopic lateral ligament reconstruction using the MOXFQ, VAS, and EQ5D patient-reported outcome measures (PROMs).

Methods

This prospective series included 38 patients who underwent arthroscopic lateral ligament reconstruction for chronic ankle instability between December 2019 and April 2022. All patients completed the MOXFQ, VAS, and EQ5D PROMs preoperatively, as well as at6, and 12 months postoperatively. The MOXFQ is a disease-specific PROM that assesses foot and ankle function, while the VAS measures pain and the EQ5D evaluates health-related quality of life.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_12 | Pages 7 - 7
1 Jun 2016
Stone OD Ray R Thomson C Gibson J
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There is a paucity of published literature regarding the long-term outcomes of the modern generations of total joint arthroplasty (TJA) of the first metatarsophalangeal joint. Between 1999 and 2001, we recruited 63 patients into a randomised controlled trial of arthrodesis vs TJA. The 2 year results were published in 2005.

At a mean follow-up 15.2 years (range 13.2–17.2), all patients from the original trial were contacted. Data were collected in the form of visual analogue score for pain (VAS), visual-Analogue-Scale Foot and Ankle (VAS FA) as well as information on any revision procedures.

Data were available from all surviving patients (66 toes 53 patients). There was no difference in pain scores between the arthrodesis group and arthroplasty group 7.4 ± 15.7 vs 15.7 ± 19.7 (p=0.06). There was also no difference in the VAS FA scores as a whole 88.9 ± 12.9 vs 86.1 ± 17.1 (p = 0.47), or when divided into its 3 components (pain, function and other complaints). There was however a significant difference with regards to patient satisfaction with the arthrodesis group outperforming the TJA group: 95.5 ± 10.4 vs 83.6 ± 20.9 (p<0.01). There was a significantly higher rate of revision surgery in the TJA group when compared to the arthrodesis group (p= 0.009).

At 15 years the patients that underwent arthrodesis were more satisfied and had a greater survivorship compared to TJA, however there was no difference in outcome with regards to pain or function between the two groups. Based on the results of this study arthrodesis remains the ‘gold standard’ due to excellent pain relief, high function and low risk of revision surgery.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 590 - 590
1 Oct 2010
Ray R Jameson S Kumar S
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Background: Calcaneal osteotomy is performed commonly as an adjunct to many corrective procedures of the abnormal hindfoot. Preservation of the hindfoot joints restores the normal biomechanics and can potentially delay arthritic changes in adjacent joints. Calcaneal osteotomy improves the weight bearing alignment of the foot by reducing varus or valgus deformity without impairing subtalar or mid-tarsal joint function. We are unaware of any studies documenting the complication rates associated with this procedure.

Methods: 36 calcaneal osteotomies (medial and lateral displacement, and Dwyer) were performed on 35 patients between April 2005 and October 2007 by the senior surgeon. Data was collected retrospectively by review of casenotes and assessment of radiographs. Average age was 54 years (range 18 to 81) and mean time of follow-up was 22 months (6 to 36). Indications were varus OA deformity (40%), Posterior tibialis tendon deficiency (30%), Charcot-Marie-Tooth (12%) and pes cavus (17%).

Results: All case notes and radiographs were available for analysis. Eight patients (22%) developed a complication. One patients (5%) had failed to fuse at 6 weeks following surgery. This patients developed a non-union and required re-fusion with bone grafting. Two patients (10%) had sural nerve damage, which persisted and required specialist pain team involvement. Two patients developed symptoms relating to prominent screws. A further two patients had wound breakdown and one had a superficial infection. In total, there were five further procedures (14%) – two directly related to problems with the calcaneal osteotomy. All osteotomies united within a translation distance of 10% in the sagittal plane.

Discussion: Calcaneal osteotomy is a useful adjunct procedure for correcting anatomical malalignment of the hindfoot in several conditions, with an acceptable complication rate and a low re-operation rate.


The Journal of Bone & Joint Surgery British Volume
Vol. 59-B, Issue 3 | Pages 342 - 348
1 Aug 1977
Muscolo D Kawai S Ray R

In vitro studies on isolated bone cells were undertaken to investigate the presence of transplantation (histocompatibility) antigens. Bone cells were cultured with allogeneic lymphocytes and exposed to cytotoxic sera containing antibodies against transplantation antigens, to determine their antigenic profile. Preliminary results suggest that bone cells may not express lymphocyte stimulating antigens in an active form, at least after the isolation procedure performed. On the other hand, bone cells were killed by cytotoxic antibodies in a specific way, providing evidence for the presence of serologically defined (SD) transplantation antigens on the cell surface. Additional studies with absorbed sera suggest "sharing" of histocompatibility antigens between bone cells and lymphocytes. The relevance of the surface antigens of bone cells to clinical fields such as bone allotransplantation, susceptibility to various orthopaedic diseases and skeletal sarcomata is discussed.