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The Bone & Joint Journal
Vol. 101-B, Issue 3 | Pages 236 - 237
1 Mar 2019
Perry DC Paton RW


The Bone & Joint Journal
Vol. 100-B, Issue 6 | Pages 806 - 810
1 Jun 2018
Choudry QA Paton RW

Aims

The aim of this prospective cohort study was to evaluate the effectiveness of the neonatal hip instability screening programme.

Patients and Methods

The study involved a four-year observational assessment of a neonatal hip screening programme. All newborns were examined using the Barlow or Ortolani manoeuvre within 72 hours of birth; those with positive findings were referred to a ‘one-stop’ screening clinic for clinical and sonographic assessment of the hip. The results were compared with previous published studies from this unit.


The Bone & Joint Journal
Vol. 100-B, Issue 5 | Pages 675 - 679
1 May 2018
Anderton MJ Hastie GR Paton RW

Aims

The aim of this study was to identify the association between asymmetrical skin creases of the thigh, buttock or inguinal region and pathological developmental dysplasia of the hip (DDH).

Patients and Methods

Between 1 January 1996 and 31 December 2016, all patients referred to our unit from primary or secondary care with risk factors for DDH were assessed in a “one stop” clinic. All had clinical and sonographic assessment by the senior author (RWP) with the results being recorded prospectively. The inclusion criteria for this study were babies and children referred with asymmetrical skin creases. Those with a neurological cause of DDH were excluded. The positive predictive value (PPV) for pathological DDH was calculated.


The Bone & Joint Journal
Vol. 99-B, Issue 11 | Pages 1533 - 1536
1 Nov 2017
Nie K Rymaruk S Paton RW

Aims

A clicky hip is a common referral for clinical and sonographic screening for developmental dysplasia of the hip (DDH). There is controversy regarding whether it represents a true risk factor for pathological DDH. Therefore a 20-year prospective, longitudinal, observational study was undertaken to assess the relationship between the presence of a neonatal clicky hip and pathological DDH.

Patients and Methods

A total of 362 infants from 1997 to 2016 were referred with clicky hips to our ‘one-stop’ paediatric hip screening clinic. Hips were assessed clinically for instability and by ultrasound imaging using a simplified Graf/Harcke classification. Dislocated or dislocatable hips were classified as Graf Type IV hips.


The Bone & Joint Journal
Vol. 97-B, Issue 2 | Pages 265 - 269
1 Feb 2015
Mace J Paton RW

Over a 15-year prospective period, 201 infants with a clinically unstable hip at neonatal screening were subsequently reviewed in a ‘one stop’ clinic where they were assessed clinically and sonographically. Their mean age was 1.62 weeks (95% confidence interval (CI) 1.35 to 1.89). Clinical neonatal hip screening revealed a sensitivity of 62% (mean, 62.6 95%CI 50.9 to 74.3), specificity of 99.8% (mean, 99.8, 95% CI 99.7 to 99.8) and positive predictive value (PPV) of 24% (mean, 26.2, 95% CI 19.3 to 33.0). Static and dynamic sonography for Graf type IV dysplastic hips had a 15-year sensitivity of 77% (mean, 75.8 95% CI 66.9 to 84.6), specificity of 99.8% (mean, 99.8, 95% CI 99.8 to 99.8) and a PPV of 49% (mean, 55.1, 95% CI 41.6 to 68.5). There were 36 infants with an irreducible dislocation of the hip (0.57 per 1000 live births), including six that failed to resolve with neonatal splintage.

Most clinically unstable hips referred to a specialist clinic are female and stabilise spontaneously. Most irreducible dislocations are not identified from this neonatal instability group. There may be a small subgroup of females with instability of the hip which may be at risk of progression to irreducibility despite early treatment in a Pavlik harness.

A controlled study is required to assess the value of neonatal clinical screening programmes.

Cite this article: Bone Joint J 2015;97-B:265-9.


The Bone & Joint Journal
Vol. 96-B, Issue 11 | Pages 1553 - 1555
1 Nov 2014
Paton RW Choudry QA Jugdey R Hughes S

There is controversy whether congenital foot abnormalities are true risk factors for pathological dysplasia of the hip. Previous United Kingdom screening guidelines considered congenital talipes equinovarus (CTEV) to be a risk factor for hip dysplasia, but present guidelines do not. We assessed the potential relationship between pathological dysplasia of the hip and fixed idiopathic CTEV.

We present a single-centre 21-year prospective longitudinal observational study. All fixed idiopathic CTEV cases were classified (Harrold and Walker Types 1 to 3) and the hips clinically and sonographically assessed. Sonographic Graf Type III, IV and radiological irreducible hip dislocation were considered to be pathological hip dysplasia.

Over 21 years there were 139 children with 199 cases of fixed idiopathic CTEV feet. Sonographically, there were 259 normal hips, 18 Graf Type II hips, 1 Graf Type III hip and 0 Graf Type IV hip. There were no cases of radiological or sonographic irreducible hip dislocation.

Fixed idiopathic CTEV should not be considered as a significant risk factor for pathological hip dysplasia. This conclusion is in keeping with the current newborn and infant physical examination guidelines in which the only risk factors routinely screened are family history and breech presentation. Our findings suggest CTEV should not be considered a significant risk factor in pathological dysplasia of the hip.

Cite this article: Bone Joint J 2014;96-B:1553–5.


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_1 | Pages 11 - 11
1 Jan 2014
Talbot CL Paton RW
Full Access

A 15 year prospective, observational cohort study was undertaken to assess selective screening of DDH in males and females referred with risk factors only.

Individuals born breech or with evidence of a strong family history for DDH were the ‘risk factors’ studied. All were clinically examined and sonographically screened by one Consultant Paediatric Orthopaedic surgeon. Irreducible hip dislocation rate was the primary outcome measure.

From a cohort of 64670 live births, 2,984 neonates/infants, 46.1 per 1000 live births [95% CI 44.6 to 47.8 per 1000 live births] were referred and sonographically screened with ‘pure’ risk factors of breech presentation and/or family history, with clinical stability. 1360 were male, of which 4 were identified as having ‘pathological’ DDH; an incidence of 1 in 333 of those males referred [95 CI 0.001, 0.008]. 1624 were female, of which 45 were identified as having ‘pathological’ DDH; an incidence of 1 in 36 of those females referred [95% CI 0.021, 0.037]. There was a significant difference in the number of female individuals sonographically diagnosed as having ‘pathological’ DDH compared to males (p<0.001). Four individuals were diagnosed with irreducible hip dislocation, 0.06 per 1000 live births [95% CI 0.24, 0.159 per 1000 live births]. All were in females. Additionally, there were 2 female individuals; both with family history of DDH (1st cousin splinted and sister splinted, respectively) as a risk factor, referred late.

Our study suggests that there is a significant difference between the incidence of female and male individuals diagnosed with ‘pathological’ DDH, in those referred purely with risk factors (breech and family history). These findings question the current screening policy for ultrasound examination of males with risk factors in the absence of clinical instability, and may influence future DDH screening programme policy.

Level of evidence: II


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 12 | Pages 1695 - 1699
1 Dec 2010
Fox AE Paton RW

This prospective cohort study aimed to investigate the relationship between developmental dysplasia of the hip and mode of delivery in 571 consecutive breech infants using a modified Graf’s static morphological method to grade the severity of dysplasia.

In this group, 262 infants were born by planned Caesarian section, 223 by emergency section and 86 vaginally. Taking all grades of hip dysplasia into account (Graf types II, III and IV), there was no statistical difference in the incidence of dysplasia between the groups (elective section 8.4%, emergency section 8.1% and vaginal delivery 7.0%). However, when cases with Graf type II dysplasia, which may represent physiological immaturity, were excluded, the rate of type III and IV hips, which we consider to be clinically relevant, increased in the vaginally delivered group (4.7%) compared with the elective section group (1.1%), with a relative risk of approximately 1:4 (95% confidence interval 1.03 to 15.91). No difference was observed between the emergency and elective section groups, or between the emergency section and vaginally delivered groups.

This study supports previous published work, with the added value that the diagnoses were all confirmed by ultrasound.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 5 | Pages 655 - 658
1 May 2009
Paton RW Choudry Q

In a prospective study over 11 years we assessed the relationship between neonatal deformities of the foot and the presence of ultrasonographic developmental dysplasia of the hip (DDH). Between 1 January 1996 and 31 December 2006, 614 infants with deformities of the foot were referred for clinical and ultrasonographic evaluation. There were 436 cases of postural talipes equinovarus deformity (TEV), 60 of fixed congenital talipes equinovarus (CTEV), 93 of congenital talipes calcaneovalgus (CTCV) and 25 of metatarsus adductus.

The overall risk of ultrasonographic dysplasia or instability was 1:27 in postural TEV, 1:8.6 in CTEV, 1:5.2 in CTCV and 1:25 in metatarsus adductus.

The risk of type-IV instability of the hip or irreducible dislocation was 1:436 (0.2%) in postural TEV, 1:15.4 (6.5%) in CTCV and 1:25 (4%) in metatarsus adductus. There were no cases of hip instability (type IV) or of irreducible dislocation in the CTEV group.

Routine screening for DDH in cases of postural TEV and CTEV is no longer advocated. The former is poorly defined, leading to the over-diagnosis of a possibly spurious condition. Ultrasonographic imaging and surveillance of hips in infants with CTCV and possibly those with metatarsus adductus should continue.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 214 - 214
1 May 2009
Choudry Q Paton RW
Full Access

Aim: To assess the relationship between different types of foot deformity as risk factors in developmental dysplasia of the hip.

Methods: In the Blackburn district foot deformities were referred as risk factors in a screening programme for DDH. All hips were imaged ultrasonographically using a modified Graf morphological and Harcke dynamic method: type I, II, III and IV.

Statistical analysis compared relative risks, odds ratios, 95% confidence intervals for relative risk and P values using Chi the squared test.

Results: Total 585 cases, 432 postural equinovarus deformities (TEV), 60 fixed congenital talipes equinovarus (CTEV), 93 congenital talipes calcaneovalgus (CTCV) & 25 metatarsus adductus.

Conclusion: Routine screening for DDH in cases of postural TEV & fixed CTEV is no longer advocated. The deformity of postural TEV is poorly defined in the literature leading to over diagnosis. The screening of CTCV & metatarsus adductus should continue.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 522 - 522
1 Aug 2008
Sloan AG Hinduja K Paton RW
Full Access

Purpose of study: Recent literature suggests the mode of delivery; either normal vaginal delivery (NVD) or caesarean section (LSCS) influences the incidence of DDH for term breech infants. This study examines whether the incidence of DDH amongst term breech infants is related to the mode of delivery.

Methods: All term infants born breech between 1st April 1995 and 31st March 2002 were included. All infants who presented breech were screened by ultrasound as part of an ongoing longitudinal cohort study. Data regarding mode of delivery, either NVD or LSCS elective or LSCS emergency was obtained from hospital records. DDH is a spectrum from minor dysplasia to dislocated irreducible hips. DDH was recorded according to the modified Graf classification.

Results: During the 7-year period 25,919 infants were born in the study population. 996 infants presented as breech, fulfilling the inclusion criteria. 164 (16.5%) were normal vaginal deliveries. 167 (16.8%) had emergency caesarean section. 664 (66.7%) had elective caesarean section.

In total 48 patients were diagnosed with DDH. 10 patients had bilateral DDH giving a total of 58 dysplastic hips.

Conclusions: Infants delivered by normal vaginal delivery or emergency caesarean section had a significantly higher incidence of DDH than those delivered by elective caesarean section. This study suggests that the mode of delivery does influence the stability of hips in infants lying breech at term.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 10 | Pages 1379 - 1381
1 Oct 2007
Sandher DS Al-Jibury M Paton RW Ormerod LP

We report 79 cases of bone and joint tuberculosis between 1988 and 2005, eight of which were in the Caucasian population and 71 in the non-white population.

The diagnosis was made in the majority (73.4%) by positive bacteriology and/or histology. The mean age at the time of diagnosis was higher in the Caucasian group at 51.5 years (28 to 66) than in the South Asian group at 36.85 years (12 to 93). Only one patient had previous BCG immunisation.

The spine was the site most commonly affected (44.3%). Surgical stabilisation and/or decompression was performed in 23% of these cases because of cord compression on imaging or the presence of neurological signs.

A six-month course of chemotherapy comprising of an initial two months of rifampicin, isoniazide, pyrazinamide and sometimes ethambutol followed by four months treatment with rifampicin and isoniazide, was successful in all cases without proven drug resistance.


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 9 | Pages 1264 - 1266
1 Sep 2005
Paton RW Hinduja K Thomas CD

Of the 34 723 infants born between 1 June 1992 and 31 May 2002, the hips of 2578 with clinical instability or at-risk factors for developmental dysplasia of the hip were imaged by ultrasound.

Instability of the hip was present in 77 patients, of whom only 24 (31.2%) had an associated risk factor. From the ‘at-risk’ groups, the overall risk of type-III dysplasia, instability and irreducibility was 1:15 when family history, 1:27 when breech delivery and 1:33 when foot deformity were considered as risk factors. Of those hips which were ultrasonographically stable, 88 had type-III dysplasia.

A national programme of selective ultrasound screening of at-risk factors for the diagnosis of hip dislocation or instability alone cannot be recommended because of its low predictive value (1:88). However, the incidence of type-III dysplasia and hip dislocation or dislocatability in the groups with clinical instability, family history, breech position and possibly postural foot deformity as risk factors could justify a programme of selective ultrasound imaging.


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 1 | Pages 135 - 136
1 Jan 2005
PATON RW MUMTAZ H


The Journal of Bone & Joint Surgery British Volume
Vol. 85-B, Issue 7 | Pages 1086 - 1086
1 Sep 2003
PATON RW PANIKER J


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 109 - 109
1 Feb 2003
Paton RW Hossain S Eccles K
Full Access

The use of targeted ultrasound screening for ‘at risk’ hips in order to reduce the rate of surgery in developmental dysplasia of the hip (DDH) is unproven. A prospective trial was undertaken in an attempt to clarify this matter.

Over an 8-year period, there were 28, 676 live births. Unstable and ‘at risk’ hips were routinely targeted for ultrasound examination. One thousand eight hundred and six infants were ultrasounded, 6. 3% of the birth population.

Twenty-six children (19 dislocations and 7 dysplasia) required surgical intervention (0. 91 per 1000 births for DDH/0. 66 per 1000 births for dislocation)

Targeted ultrasound screening does not reduce the overall rate of surgery compared with the best conventional clinical screening programmes. The development of a national targeted ultrasound screening programme for ‘at risk’ hips cannot be justified on a cost or result basis.


The Journal of Bone & Joint Surgery British Volume
Vol. 84-B, Issue 1 | Pages 104 - 107
1 Jan 2002
Jari S Paton RW Srinivasan MS

Between 1992 and 1997, we undertook a prospective, targeted clinical and ultrasonographic hip screening programme to assess the relationship between ultrasonographic abnormalities of the hip and clinical limitation of hip abduction. A total of 5.9% (2 of 34) of neonatal dislocatable hips and 87.5% (7 of 8) of ‘late’ dislocated hips seen after the age of six months, presented with unilateral limitation of hip abduction. All major (Graf type III) and 44.5% of minor (Graf type II) dysplastic hips presented with this sign.

Statistically, bilateral limitation of hip abduction was not a useful clinical indicator of underlying hip abnormality because of its poor sensitivity, but unilateral limitation of abduction of the hip was a highly specific (90%) and reasonably sensitive sign (70%). It was more sensitive than the neonatal Ortolani manoeuvre, which has been considered to be the method of choice. It was, however, not sensitive enough to be of value as a routine screening test in developmental dysplasia of the hip.

We consider unilateral limitation of hip abduction to be an important clinical sign and its presence in an infant over the age of three to four months makes further investigation essential.


The Journal of Bone & Joint Surgery British Volume
Vol. 83-B, Issue 4 | Pages 618 - 618
1 May 2001
HOSSAIN S PATON RW


The Journal of Bone & Joint Surgery British Volume
Vol. 82-B, Issue 4 | Pages 619 - 619
1 May 2000
SAMPATH JS PATON RW


The Journal of Bone & Joint Surgery British Volume
Vol. 82-B, Issue 2 | Pages 160 - 164
1 Mar 2000
Jones DH Dezateux CA Danielsson LG Paton RW Clegg J