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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_18 | Pages 12 - 12
1 Nov 2017
Reidy M Faulkner A Grupping R Mayne A Campbell D MacLean J
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Prophylactic fixation of the contralateral hip in cases of unilateral slipped capital femoral epiphysis (SCFE) remains contentious. Our senior author reported a 10 year series in 2006 that identified a rate of subsequent contralateral slip of 25percnt; when prophylactic fixation was not performed. This led to a change in local practice and employment of prophylactic fixation as standard. We report the 10 year outcomes following this change in practice.

A prospective study of all patients who presented with diagnosis of SCFE between 2004 and 2014 in our region. Intra-operative complication and post-operative complication were the primary outcomes. 31 patients presented during the study period: 16 male patients and 15 female patients. The mean age was 12.16 (8–16, SD 2.07). 25 patients had stable SCFE and 5 had unstable SCFE. Stability was uncertain in 1 patient. 25 patients had unilateral SCFE and 6 had bilateral SCFE. 24 patients who had unilateral SUFE had contralateral pinning performed. 1 unilateral SCFE did not have contralateral pinning performed as there was partial fusion of physis on contralateral side.

In the hips fixed prophylactically there was 1 cases of transient intraoperative screw penetration into the joint and 1 case of minor wound dehiscence. There were no cases or chondrolysis or AVN. There were no further contralateral slips. This change in practice has been adopted with minimal complication. The fixation of the contralateral side is not without risk but by adopting this model the risk of subsequent slip has been reduced from 25percnt; to 0percnt;.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_18 | Pages 13 - 13
1 Nov 2017
Dalgleish S Nicol G Faulkner A Sripada S
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Laminar airflow systems are universal in current orthopaedic operating theatres and are assumed to be associated with a lower risk of contamination of the surgical wound and subsequent early infection. Evidence to support their use is limited and sometimes conflicting. We investigated whether there were any differences in infection rates (deep and superficial) between knee and hip arthroplasty cases performed in non-laminar and laminar flow theatres at 10 year follow-up.

Between 2002 and 2006, 318 patients underwent knee and hip arthroplasty in a non-laminar flow theatre. Prospectively collected local arthroplasty audit data was collected including superficial and deep infection, revision for infection and functional outcomes. A cohort of patients from the same time period, who underwent knee and hip arthroplasty in a laminar flow theatre, were matched for age, sex, body mass index (BMI), operative approach, implant and experience of surgeon.

Superficial infection rates were lower overall in the non-laminar flow theatre (2.2percnt; versus 4.7percnt;), with a significantly lower superficial infection rate for knee arthroplasty performed in the non-laminar flow theatre (2percnt; versus 6.9percnt;). The deep infection rates were similar (1.3percnt; vs 1.9percnt;) for both laminar and non-laminar flow theatre respectively. Revision rates for infection were similar between both groups (0.9percnt; in non-laminar flow theatre vs 0.3percnt; in laminar flow)

Whilst the causes of post-operative surgical site infection are multifactorial, our results demonstrate that at long –term follow-up, there was no increased risk of infection without laminar flow use in our theatre.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_18 | Pages 9 - 9
1 Nov 2017
Powell-Bowns M Faulkner A Yapp L Littlechild J Arthur C
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There is much debate regarding the use of continuous-compartment-pressure-monitoring (CCM) in the diagnosis of acute compartment syndrome (ACS).

We retrospectively reviewed the management of all patients (aged 15 and over) who were admitted with a fracture of the tibial diaphysis, across 3 centres, during 2013–2015. Patient demographics, pre-existing medical problems, initial treatment, subsequent complications, methods of compartment monitoring, and follow-up were all included in the data collection. We separated patients into monitored (MG) and non-monitored groups (NMG), and compared the outcomes of their treatment. Data analysis was performed using SPSS and statistical significance was set as p < 0.05.

287 patients were included in this study (116 NMG vs. 171 MG). There were no significant differences observed in age, sex, previous medical problems, length of stay, AO classification of fracture and post-operative complications between the groups. 21 patients were suspected to have developed ACS (n=8 NMG 6.9percnt;, n=13 MG 7.6percnt;) and were treated with acute decompression fasciotomies. The average time from admission to fasciotomy was 20.3 hours (21.25hrs NMG, 19.5hrs MG p=0.448). There was no significant difference in the average length of hospital stay and documentation of complications at follow up between the 2 groups. There were no reported cases of soft tissue infections associated with the use of CCM.

This study illustrates that CCM does not increase the rate of fasciotomies in this patient group, or reduce the time to fasciotomy significantly. There was no evidence to suggest that use of CCM is associated with superficial or deep infection.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_18 | Pages 9 - 9
1 Nov 2016
Khan M Faulkner A Macinnes A Gwozdziewicz L Sehgal R Haughton B Misra A
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Peri-prosthetic wound infections can complicate total knee arthroplasty (TKA) in 1–1.5% of cases and may require the input of a combined orthopaedic and plastic surgery team. Failure of optimal management can result in periprosthetic joint infection, arthrodesis or in severe cases limb amputation.

A retrospective 11-year review of TKA patients was undertaken in a single unit. Data was collected on a proforma and patient demographics were identified by case note analysis. Incidence of periprosthetic wound infections was recorded. A protocol to standardise treatment was subsequently developed following multidisciplinary input.

56 patients over 11 years developed periprosthetic wound infection. 33 patients were available for analysis. The male:female ratio 1:0.7 with a mean age of 70 years (range: 32–88 years). 5 (15%) developed superficial infections, 4 (12%) patients developed cellulitis requiring antibiotics, 14 (42%) with superficial wound dehiscence and 2 (6%) required washout of the prosthesis with long-term antibiotic therapy. 4 (12%) were managed without plastics involvement, one leading to arthrodesis and 4 (12%) had plastic surgical input, with one leading to arthrodesis. The mean time before plastic surgical review after initial suspicion of infection was 13 weeks.

The management of periprosthetic wound infections following TKA are variable and can require a multidiscplinary ortho-plastic approach. Early plastic surgical involvement in specific cases may improve outcome. Our proposed management protocol would facilitate in standardising the management of these complex patients.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_12 | Pages 6 - 6
1 Jun 2016
Davies P Mayne A Faulkner A Mackinnon F Simpson J
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The availability of seven-day NHS services for patients is currently receiving widespread national attention. Rehabilitation services including physiotherapy and occupational therapy are not routinely available at the weekend. The aim of this pilot study was to determine if seven-day rehabilitation services led to improved outcomes for hip fracture patients.

All proximal femur fractures were included and formed into two cohorts. Data were collected prospectively in each cohort. Cohort one underwent standard five-day rehabilitation (n=79). Cohort two received seven-day rehabilitation (n=338). Both groups were followed up to 120 days.

No significant differences were observed between the cohorts for pre-fracture place of residence, ASA score or age. Combined median length-of-stay in hospital and rehabilitation improved from 28 to 21 days (p=0.054) Combined median length of stay for patients admitted from home improved from 26 to 19 days (p=0.016).

This pilot study suggests that a seven-day physiotherapy and occupational therapy service may result in decreased total length-of-stay in hospital and subsequent rehabilitation. This is a clear benefit for our patients but also for our hospitals and rehabilitation units where beds are at such a premium. A wider study across multiple institutions within NHS Scotland is now needed to investigate this further.


The Bone & Joint Journal
Vol. 98-B, Issue 3 | Pages 301 - 306
1 Mar 2016
Reidy MJ Faulkner A Shitole B Clift B

Aims

The long-term functional outcome of total hip arthroplasty (THA) performed by trainees is not known. A multicentre retrospective study of 879 THAs was undertaken to investigate any differences in outcome between those performed by trainee surgeons and consultants.

Patients and Methods

A total of 879 patients with a mean age of 69.5 years (37 to 94) were included in the study; 584 THAs (66.4%) were undertaken by consultants, 138 (15.7%) by junior trainees and 148 (16.8%) by senior trainees. Patients were scored using the Harris Hip Score (HHS) pre-operatively and at one, three, five, seven and ten years post-operatively. Surgical outcome, complications and survival were compared between groups. The effect of supervision was determined by comparing supervised and unsupervised trainees. A primary univariate analysis was used to select variables for inclusion in multivariate analysis.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_17 | Pages 11 - 11
1 Dec 2015
Reidy M Faulkner A Shitole B Clift B
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A multicentre retrospective study of 879 total hip replacements (THR) was undertaken to investigate any differences in outcome between trainee surgeons and consultants. The effect of trainee supervision was also assessed. The primary outcome measures were survivorship and the Harris Hip Score (HHS). Length of stay was a secondary outcome.

Patients were evaluated pre-operatively and at 1, 3, 5, 7 and 10 years post-operatively. Surgical outcome was compared between junior trainees, senior trainees and consultants. The effect of supervision was determined by comparing supervised and unsupervised trainees. There was no significant difference in post-operative HHS among consultants, senior and junior trainees at 1 year (p=0.122), at 3 years (p=0.282), at 5 years (p=0.063), at 7 years (p=0.875), or at 10 years (p=0.924) follow up. Additionally there was no significant difference in HHS between supervised and unsupervised trainees at 1 year (p=0.220), 3 years (p=0.0.542), 5 years (p=0.880), 7 years (p=0.953) and 10-year (p=0.787) follow-up. Comparison of surgical outcome between the supervised and unsupervised trainees also shows no significant difference in hospital stay (p=0.989), or implant survival years (p=0.257). This study provides evidence that when trainees are appropriately supervised, they can obtain equally good results compared with consultants when performing THR.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_12 | Pages 36 - 36
1 Nov 2015
Reidy M Faulkner A Shitole B Clift B
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Introduction

There is a paucity of research investigating the effect of the experience of the operating surgeon on the long term function and survivorship of total hip replacements (THR). With the advent of individualised surgeon data being available to patients via the National Joint Registry, the desire to avoid complications and poor performance grows. This potentially reduces the availability of operative opportunities for trainees as consultants seek to ensure good results.

Method & Results

A multicentre retrospective study of 879 THR was undertaken to investigate any differences in outcome between trainee surgeons and consultants. The effect of trainee supervision on the surgical outcome was also assessed. The primary outcome measures were survivorship and the Harris Hip Score (HHS). Rates of deep infection and dislocation were also recorded. Patients were evaluated pre-operatively and at 1, 3, 5, 7 and 10 years post-operatively. Surgical outcome was compared between junior trainees, senior trainees and consultants. The effect of supervision on final outcome was determined by comparing supervised and unsupervised trainees.

66.4% of patients were operated by consultants, 15.7% by junior trainees (ST3–5 equivalent) and 16.8% by senior trainees (ST6–8 equivalent). 10 year implant survival rates were; consultants 96.4 %, senior trainees 98.0 % and junior trainees 97.1%. There was no significant difference in post-operative HHS among consultants, senior and junior trainees at 1 year (p=0.122), 3 year (p=0.282), 5 year (p=0.063), 7 year (p=0.875), or at 10 years (p=0.924). There was no significant difference in HHS between supervised and unsupervised trainees at 1 year (p=0.220), 3 year (p=0.0.542), 5 year (p=0.880), 7 year (p=0.953) and 10-years (p=0.787). Comparison of surgical outcome between the supervised and unsupervised trainees also shows no significant difference in implant survival years (p=0.257).


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_4 | Pages 9 - 9
1 May 2015
Faulkner A Reidy M Scicluna G Baird A Prentice K Coward J Wang A Davis A Joss J
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Blood tests including liver function tests (LFTs), C-reactive protein (CRP), coagulation screens and international normalising ratios (INR) are frequently requested investigations that complement the surgical and anaesthetic pre-operative assessment of patients. The paucity of guidance available for blood requesting in acute trauma and orthopaedic admissions can lead to inappropriate requesting practices and over investigation. Unnecessary tests place an economic burden on a hospital and repeated venepuncture is unpleasant for patients.

We audited blood requesting practices and with multidisciplinary input developed guidelines to improve practice which were subsequently implemented.

Admissions over a period of one month to Ninewells Hospital and Perth Royal Infirmary were audited retrospectively. The frequency and clinical indications for LFTs, coagulation screens/INR and CRP for the duration of the patient's admission were recorded. Re-audit was carried out for one month after the introduction of the guidelines.

216 patients were included in January and 236 patients in September 2014. Total no. of LFTs requested: January 895, September 336 (−62.5%). Total no of coagulation screens/INR requested: January 307, September 210 (−31.6%). Total number of CRPs requested: January 894, September 317 (−64.5%). No. of blood requests per patient: January (M=4.81, SD 4.75), September (M=3.60, SD = 4.70). A significant decrease was observed in admission requesting and subsequent monitoring (p<0.01) for LFTs, coagulation screens/INR, CRP when the guidance was introduced.

The implementation of the bloods guidance resulted in a large reduction in admission requesting and subsequent monitoring without incident. The cost of investigation was significantly reduced, as were venepuncture rates.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 142 - 142
1 Jul 2002
Faulkner A Johnson W Eisenstein S Zhao X White B Franklin V Lyndon F Tighe B Roberts S
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Introduction: Intervertebral disc degeneration occurs with ageing and is often associated with back pain. During such degeneration, gross morphological differences between the central nucleus pulposus (NP) and outer annulus fibrosus (AF) are lost and the disc loses hydration and height due to decreased proteoglycan content. The cartilage endplate may also become calcified and this blocks the passage of nutrients into the disc, causing cell death and further degeneration. A potential therapy of degeneration is “re-inflation” of the disc with the use of hydrogels seeded with autologous disc cells. In this study, we have assessed the ability of a variety of hydrogels to support intervertebral disc cell growth.

Method: Intervertebral disc cells were isolated enzymatically from bovine tails and cultured as a monolayer in 10% foetal calf serum in DMEM containing antibiotics and ascorbic acid. This stimulates the cells to proliferate and thereby produces increased cell numbers. The cells were then seeded onto various hydrogels including hyaluronic acid (HA), 2-hydroxyethyl methacrylate (HEMA), N’N’ dimethyl methacrylate (NNDMA) and polyacryloyl morpholine (AMO) before harvesting at set time points of 1, 3, 6 and 9 days for hyaluronic acid and 1, 7, 14, 21, and 28 days for the other hydrogels. Cell number, morphology, viability and adherence to or migration into the hydrogels were assessed. Cell proliferation was also determined by immunostaining for the Ki67 antigen.

Results: Disc cells became incorporated in the HA gel, adopted a spherical morphology and remained viable for up to nine days. However, after a few days, a large proportion of the cells began to migrate through the gel to form a monolayer on the bottom of the tissue culture well. These monolayered cells became fibroblastic and proliferated. NP cells appeared to proliferate to a greater extent than AF cells both in monolayer and in suspension. Ki67 antigen immunostaining confirmed cell proliferation. On the non-porous HEMA, NNDMA and AMO, both cell types adhered and adopted a fibroblast-like morphology. Cell adhesion was greatest to the HEMA. NNDMA and AMO had lower levels of cell adherence. Both cell types became incorporated into the porous materials and adopted a rounded morphology. Cell incorporation appeared to be greatest into porous HEMA.

Conclusion: These initial studies show that intervertebral disc cells will adhere to or migrate into a variety of hydrogels and remain viable. The morphology and proliferative capacity of cells derived from both the AF and NP were responsive to the structure of the hydrogel with which they were cultured. Thus, cells were able to become fibroblastic or chondrocytic. Further analyses will reveal whether matrix synthesis by disc cells is similarly responsive to the hydrogel format. The results of these experiments suggest that the hydrogels tested have potential as support matrices in intervertebral disc repair to provide relief from discogenic low-back pain.