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Bone & Joint Research
Vol. 3, Issue 3 | Pages 76 - 81
1 Mar 2014
Okabe YT Kondo T Mishima K Hayase Y Kato K Mizuno M Ishiguro N Kitoh H

Objectives

In order to ensure safety of the cell-based therapy for bone regeneration, we examined in vivo biodistribution of locally or systemically transplanted osteoblast-like cells generated from bone marrow (BM) derived mononuclear cells.

Methods

BM cells obtained from a total of 13 Sprague-Dawley (SD) green fluorescent protein transgenic (GFP-Tg) rats were culture-expanded in an osteogenic differentiation medium for three weeks. Osteoblast-like cells were then locally transplanted with collagen scaffolds to the rat model of segmental bone defect. Donor cells were also intravenously infused to the normal Sprague-Dawley (SD) rats for systemic biodistribution. The flow cytometric and histological analyses were performed for cellular tracking after transplantation.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_16 | Pages 46 - 46
1 Apr 2013
Iga T Karita T Sato W Okazaki H Tatsumi T Touhara C Nishikawa T Nagai I Ushita M Matsumoto T Kondo T
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Introduction

In oblique olecranon fracture, fracture line begins in the trochlear notch and proceeds distally to the dorsal cortex of the ulna. We have experienced a nonunion of reverse oblique fracture.

Hypothesis

Reverse oblique olecranon fracture has instability.


The Journal of Bone & Joint Surgery British Volume
Vol. 73-B, Issue 2 | Pages 348 - 349
1 Mar 1991
Hotta Y Azuma H Kondo T Yamashina M