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Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 390 - 390
1 Jul 2011
Cobb J Logishetty K Davda K Murphy AJ Iranpour F
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Pincer femoroacetabular impingement (FAI) is cited as being the result of a socket that is either too deep or retroverted, or both. Using 3D-CT analysis, we set out to quantify the acetabular rim shape and orientation to determine the roles of these two factors in FAI.

Twenty pincer acetabulae were selected from patients undergoing image based navigated surgery, where the lateral centre edge angle was greater than 40° on plain radiographs. The normal group of disease free sockets were obtained from a CT colonography database.

Using 3D reconstruction of their CT scans, a novel method of mapping the acetabular rim profile was created. The pelvis was aligned to the anterior pelvic plane. Starting at the most anterior rim point, successive markers were placed along the rim. A best fit plane (ARP) through the acetabulum was derived, and the subtended angle (SA) between each rim marker and a normal vector from the acetabular centre was calculated. Values above 90° indicated a peak, with less than 90° representing a trough. Inclination and version were measured from a horizontal plane and the ARP, in the coronal and axial view respectively.

The results showed that asymmetric acetabular rim profiles in normal and pincer hips were very similar. However, pincer hips are significantly deeper overall (Mean SA 96±5° vs. 87±4° p< 0.00001) and at each anatomical point of the three eminences (pubic [SA: Normal 84±4° vs. Pincer 94±7° p< 0.00001], iliac [SA: 93±4° vs. 100±6° p=0.00021] and ischial [SA: 92±3° vs. 102±8° p=0.00005]) and two troughs (ilio-pubic [SA: Normal 83±4° vs. Pincer 94±8° p=0.00001] and ilio-ischial [SA: 92±3° vs. 102±8° p=0.00002]).

The orientation of normal and pincer were almost identical (Inclination: 51±3° vs. 51±6° p=0.54 and Version: 24±6° vs. 25°±7° p=0.67).

We conclude that the rim shape of pincer hips follows the same contour as normal hips. In agreement with current radiographic diagnosis, pincer-type hips are characterised by a deeper acetabulum. This ‘overcoverage’ of the femoral head confirms the biomechanical model of pincer-type impingement.

Both inclination and version in these two groups were almost identical, with no truly retroverted acetabulum seen. Pincer impingement resulting from ‘acetabular retroversion’ is a concept currently based upon radiographic signs that we have been unable to confirm in this small 3D study using the subtended angle as the key descriptor of acetabular morphology.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 182 - 183
1 May 2011
Jeyaseelan L Ward J Anand A Rhee S Eleftheriou K Cobb J
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Introduction: Preoperative planning plays an important role in any surgical procedure and total hip replacement (THR) is no exception. Templating of radiographs allows preoperative assessment of the correct size of implant to be used, lowers the risk of periprosthetic fracture, helps restore femoral offset and leg length, facilitates the optimisation of alignment and ensures the correct implants sizes are available.

With the wide scale use of Picture Archiving and Communication Systems (PACS) in the National Health Service (NHS), the potential exists for faster and more accurate templating of THRs.

Aim: In performing this study, we assessed whether there is adequate provision of the current NHS PACS to allow optimal digital templating for THRs. We also made comparison between the availability and overall ease of conventional versus digital templating.

Methods: Data was collected using a telephone questionnaire requesting information from the on-call orthopaedic Specialist Registrar (SpR) in 28 Greater London and surrounding area NHS Hospitals. Data on the availability of PACS and the ability to template using hard-copy or digital templating was collected and analysed.

Results: PACS were used in all 28 (100%) hospitals that were contacted. None performed conventional templating regularly and only 8 (28.6%) admitted to occasional templating. The predominant reason for this was difficulty in obtaining hard copies of x-rays in 12 (42.9%) hospitals, as well as lack of availability acetate templates, with 13 (46.4%) claiming that this was the case.

Digital templating software was available in 14 (50%) hospitals. Despite this, none of them performed digital templating regularly. In the 50% that did have digital templating, this was not routinely done for the following reasons:

only 3 (10.7%) allowed easy access to the software to the SpRs

only one SpR received formal training on how to use the system

only one hospital regularly used Methods: to accurately allow the software to assess magnification for accurate sizing (e.g. sizing balls)

Discussion: Digital PACS systems have made great improvement in the access of radiographs in the NHS. With regards to orthopaedic practice, however, we have shown that the benefit of digital templating is being overlooked within the NHS.


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 3 | Pages 315 - 320
1 Mar 2011
Hart AJ Ilo K Underwood R Cann P Henckel J Lewis A Cobb J Skinner J

We measured the orientation of the acetabular and femoral components in 45 patients (33 men, 12 women) with a mean age of 53.4 years (30 to 74) who had undergone revision of metal-on-metal hip resurfacings. Three-dimensional CT was used to measure the inclination and version of the acetabular component, femoral version and the horizontal femoral offset, and the linear wear of the removed acetabular components was measured using a roundness machine.

We found that acetabular version and combined version of the acetabular and femoral components were weakly positively correlated with the rate of wear. The acetabular inclination angle was strongly positively correlated with the rate of wear. Femoral version was weakly negatively correlated with the rate of wear. Application of a threshold of > 5 μm/year for the rate of wear in order to separate the revisions into low or high wearing groups showed that more high wearing components were implanted outside Lewinnek’s safe zone, but that this was mainly due to the inclination of the acetabular component, which was the only parameter that significantly differed between the groups.

We were unable to show that excess version of the acetabular component alone or combined with femoral version was associated with an increase in the rate of wear based on our assessment of version using CT.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 392 - 392
1 Jul 2010
Hart A Lenihan J Cobb J Henckel J
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Introduction: The successful outcome from metal-on-metal hip resurfacing is partly dependent on the restoration of the natural biomechanics of the hip joint. Valid measurement of the geometry of the reconstructed hip is challenging using plain radiographs. CT is more accurate and precise yet rarely used to assess hip geometry. Our aims were 1) to quantify the agreement between radiographic and CT measurement of horizontal femoral offset (HFO); 2) to determine the relationship between HFO and patient gender and size; and 3) To compare HFO of the reconstructed hip to the contralateral hip.

Method: We used plain radiograph and CT data from 42 patients (23 male and 19 female) from a consecutive series with unilateral metal-on-metal hip resurfacings. We measured HFO of both hips (component and contralateral) using plain radiographs (with PACS) and CT (with Robin 3D software). Pelvic width and radial head sizes were measured on CT. Measurements were made in triplicate by 2 observers.

We graded the contralateral hip for severity of joint space narrowing on plain radiographs.

Results: There was considerable disagreement between CT and plain radiographs for HFO. HFO was statistically different between genders (p=0.0004). HFO correlated with femoral head radius (0.57, p=0.0002), but not patient size (for height (0.29, p=0.13), or pelvic width (0.25, p=0.11). There was a wide range of HFO of the contralateral hips that was comparable to the reconstructed hip.

Conclusion: To our knowledge this is the first study to show the importance of measuring HFO using CT. HFO was found to be correlated to gender and femoral head radius, but not with any other parameters of patient size. The wide range of offset was considerably greater than is available from current total hip replacement designs. Hip resurfacing may overcome this.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 318 - 318
1 May 2010
Brust K Alsop H Henckel J Cobb J
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Introduction: Unicompartmental knee Arthroplasty (UKA) is a commonly used and accepted treatment for Osteoarthritis (OA) in the medial compartment. How-ever, despite some good results1 there is still a reluctance to use this procedure in the lateral compartment for the same indications, as the procedure is considered technically difficult, and not as successful2. This study reports the clinical outcome of lateral UKAs in comparison with medial UKAs, TKAs and a normal population group using a knee score designed to highlight the shortcomings of TKA3.

Methods: 20 consecutive patients over 2 years following lateral UKA were functionally assessed. They were compared with 3 groups of 20 age and sex matched patients: those who had undergone medial UKA or TKA in the same time period, or normal controls from an upper limb clinic. Clinical function was assessed at least 2 years postoperatively, using the ‘total knee questionaire’3. This consists of 55 scaled multiple choice questions. The score is derived from the product of three scales: the importance of a specific activity, the frequency with which it is undertaken, and the ease with a patient can perform it.

Results: 90% of the patients reported that they were either satisfied or very satisfied with their lateral UKA, with 95% of the patients in the medial UKA group and 75% in the TKA group reaching this level of satisfaction. The average Composite Score for the lateral UKA group was significantly better compared with the TKA group (p < 0, 05). (Kneeling – (5,72/4,45), Gardening – (7,32/5,18), Pivoting – (7,83/6,78) and Walking with heavy bags (8,2/5,97)). The Total Composite Score was significantly better (p< 0, 05) in Patients after lateral UKA (7,14) compared to patients who underwent TKA (5,99). No statistically significant differences in the Total Composite Score was found between both the lateral & medial UKA patients taken as a single group compared with the control group.

Conclusion: Lateral Unicompartmental Knee Arthroplasty achieves superior knee function in comparison to Total Knee Arthroplasty, so is worth considering as an option in for early OA of the lateral compartment.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 321 - 321
1 May 2010
boroujeni FI Merican A Dandachli W Amis A Cobb J
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Introduction: Patellofemoral complications are one of the major causes for revision surgery. In the prosthetic knee, the main determinant within the patellofemoral mechanism is said to be the design of the groove (Kulkarni et al., 2000). Other studies characterising the native trochlear groove used indirect methods such as photography, plain radiographs and measurements using probes and micrometer. The aim of this study was to define the 3-dimensional geometry of the femoral trochlear groove. We used CT scans to describe the geometry of the trochlear groove and its relationship to the tibiofemoral joint in terms of angles and distances.

Materials and Methods: CT scans of 45 normal femurs were analysed using custom designed imaging software. This enabled us to convert the scans to 3D and measure distances and angles. The flexion axis of the tibiofemoral joint was found to be a line connecting the centres of the spheres fitted to posterior femoral condyles. These two centres and the femoral head centre form a frame of reference for reproducible femoral alignment. The trochlear geometry was defined by fitting circles to cross sectional images and spheres to 3D surfaces. Axes were constructed through these centres. The deepest points on the trochlear groove were identified using quad images and Hounsfield units. After aligning the femur using different axes, the location of the groove was examined in relation to the mid plane between the centres of flexion of the condyles.

Results: The deepest points on the trochlear groove can be fitted to a circle with a radius of 23mm (S.D. 4mm) and an R.M.S error of 0.3mm. The groove is positioned laterally (especially in its mid portion) in relation to the femoral mechanical and anatomical axes. It was also lateral to the perpendicular bisect of the transcondylar axes. After aligning the anatomical axis in screen the trochlear groove can be described on average to be linear with less than 2 mm medial/lateral translation.

In the sagital view, the centre of the circle is offset by 21mm (S.D.3mm) at an angle of 67° (S.D. 7°) from a line connecting the midpoint between the centres of the femoral condyles and the femoral head centre.

On either end of this line, the articular surface of the trochlea can be fitted to spheres of radius 30mm (S.D. 6mm) laterally and 27mm (S.D. 5mm) medially, with an rms of 0.4mm.

Discussion: The location and configuration of the inter-condylar groove of the distal femur is clinically significant in the mechanics and pathomechanics of the patellofemoral articulation. This investigation has allowed us to characterise the trochlear groove.

This can be of use in planning and performing joint reconstruction and have implications for the design of patello-femoral replacements and the rules governing their position.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 296 - 296
1 May 2010
Dandachli W Nakhla A Iranpour F Kannan V Amis A Cobb J
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Acetabular centre positioning in the pelvis has a profound effect on hip joint function. The force–and moment-generating capacities of the hip muscles are highly sensitive to the location of the hip centre. We describe a novel 3D CT-based system that provides a scaled frame of reference (FOR) defining the hip centre coordinates in relation to easily identifiable pelvic anatomic landmarks. This FOR is more specific than the anterior pelvic plane (APP) alone, giving depth, height and width to the pelvis for both men and women under-going hip surgery.

CT scans of 22 normal hips were analysed. There were 14 female and 8 male hips. The APP was used as the basis of the coordinate system with the origin set at the right anterior superior iliac spine. After aligning the pelvis with the APP, the pelvic horizontal dimension (Dx) was defined as the distance between the most lateral points on the iliac crests, and its vertical dimension (Dy) was the distance between the highest point on the iliac wing and the lowest point on ischial tuberosity. The pelvic depth (Dz) was defined as the horizontal distance between the posterior superior iliac spine and the ipsilateral ASIS. The ratios of the hip centre’s x, y, and z coordinates to their corresponding pelvic dimensions (Cx/Dx, Cy/Dy, Cz,Dz) were calculated. The results were analysed for men and women.

For a given individual the hip centre coordinates can be derived from pelvic landmarks. We have found that the mean Cx/Dx measured 0.09 ± 0.02 (0.10 for males, 0.08 for females), Cy/Dy was 0.33 ± 0.02 (0.30 for males, 0.35 for females), and Cz/Dz was 0.37 ± 0.02 (0.39 for males and 0.36 for females). There was a statistically significant gender difference in Cy/Dy (p=0.0001) and Cz/Dz (p=0.03), but not in Cx/Dx (p=0.17). Anteversion for the male hips averaged 19° ± 3°, and for the female hips it was 26° ± 5°. Inclination measured 56° ± 1° for the males and 55° ± 4° for the females. Reliability testing showed a mean intra-class correlation coefficient of 0.95. Bland-Altman plots showed a good inter-observer agreement.

This method relies on a small number of anatomical points that are easily identifiable. The fairly constant relationship between the centre coordinates and pelvic dimensions allows derivation of the hip centre position from those dimensions. Even in this small group, it is apparent that there is a difference between the sexes in all three dimensions. Without the need for detailed imaging, the pelvic points allow the surgeon to scale the patient’s pelvis and thereby know within a few millimetres the ‘normal’ position of the acetabulum for both men and women. This knowledge may be of benefit when planning or undertaking reconstructive hip surgery especially in patients with hip dysplasia or bilateral hip disease where there is no reference available for planning the surgery.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 398 - 399
1 Sep 2009
Dandachli W Nakhla A Iranpour F Kannan V Cobb J
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Although acetabular centre positioning has a profound effect on hip joint function, there are very few studies describing accurate methods of defining the acetabular centre position in 3D space. Clinical and plain radiographic methods are inaccurate and unreliable. We hypothesize that a 3D CT-based system would provide a gender-specific scaled frame of reference defining the hip centre coordinates in relation to easily identifiable pelvic anatomic landmarks.

CT scans of thirty-seven normal hips (19 female and 18 male) were analysed. The ratios of the hip centre coordinates to their corresponding pelvic dimensions represented its horizontal (x), vertical (y), and posterior (z) scaled offsets (HSO, VSO, and PSO).

The mean HSO for females was 0.08 ± 0.018, mean VSO was 0.35 ± 0.018, and mean PSO was 0.36 ± 0.017. For males HSO averaged 0.10 ± 0.014, VSO was 0.32 ± 0.015, and PSO was 0.38 ± 0.013. There was a statistically significant gender difference in all three scaled offsets (p=0.04, 0.002, and 0.03 for HSO, VSO, and PSO respectively). Inter-observer agreement tests showed a mean intra-class correlation coefficient of 0.95.

We conclude that this frame of reference is gender-specific giving a unique scale to the patient and allowing reliable derivation of the position of the hip centre from the pelvic dimensions alone. The gender differences should be borne in mind when positioning the centre of a reconstructed hip joint. Using this method, malpositioning, particularly in the antero-posterior (or z) axis, can be identified and addressed in a malfunctioning hip replacement. Pathological states, such as dysplasia and protrusio, can also be accurately described and surgery addressing them can be precisely planned.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 503 - 503
1 Sep 2009
Cobb J
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32 students of surgical technology were instructed in hip resurfacing, and shown detailed plans of the desired operative outcome for the 3 cam type hips. They then used conventional instruments, image-free navigation (brainlab) and image based navigation(Acrobot).

Only image based navigation performed well enough at navigating these difficult cam type hips with novice surgeons. Conventional instruments were not sufficient, with a tendency for the novice to put the hip in varus and translated low on the femoral neck. Image free navigation was more accurate than conventional instruments, avoiding the serious complication of notching but the range of error was 18mm and 10¡.

Image based navigation appears to be fit for purpose in delivering both the accuracy and the precision needed by the novice surgeon in the skills laboratory who needs timely feedback so his clinical experience may start substantially further along the learning curve of this or any other technically demanding operation.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 399 - 399
1 Sep 2009
Dixon H Dandachli W Iranpour F Kannan V Cobb J
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The rotational alignment of the tibia is an as yet unresolved issue for arthroplasty surgeons. Functional variation may be due to minor malrotation of the tibial component. The aim was to find a reliable method for positioning the tibial component in arthroplasty.

CT scans of 21 knees were reconstructed in three dimensions and oriented vertically. A plane was taken 20 mm below the tibial spines. The centre of each tibial condyle was calculated from points taken round that condylar cortex. A tibial tubercle centre was also generated as the centre of the circle that best fit points on the surface of the tubercle in the plane of its most prominent point.

The derived points were identified by three observers with errors of 0.6 – 1mm. The medial and lateral tibial centres were constant features (radius 24mm ± 3mm, and 22mm ± 3mm respectively). An ‘anatomic’ axis was created perpendicular to a line joining these two points. The tubercle centre was found 20mm ± 7mm lateral to the medial tibial centre. Compared to this axis, an axis perpendicular to the posterior condylar axis was internally rotated by 6° ± 3°. An axis based on the tibial tubercle and the tibial spines was also internally rotated by 6° ± 10°.

We conclude that alignment of the knee when based on this ‘anatomic’ axis is more reliable than either of the posterior surfaces. It is also more reliable than any axis involving the tubercle, which is the least reliable feature in the region. The ‘anatomic’ axis can be used in navigated knee arthroplasty for referencing the rotational alignment of the tibial component.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 399 - 400
1 Sep 2009
Brust K Khanduja V Dandachli W Iranpour F Henckel J Hart AJ Cobb J
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Radiological measurements are an essential component of the assessment of outcome following knee arthroplasty. However, plain radiographic techniques can be associated with significant projectional errors because they are a two-dimensional (2D) representation of a three-dimensional (3D) structure. Angles that are considered within the target zone on one film may be outside that zone on other films. Moreover, these parameters can be subject to significant inter-observer differences when measured. The aim of our study therefore was to quantify the variability between observers evaluating plain radiographs following Unicompartmental knee arthroplasty.

Twenty-three observers, made up of Orthopaedic Consultants and trainees, were asked to measure the coronal and sagittal alignment of the tibial and femoral components from the post-operative long-leg plain radiograph of a Unicompartmental knee arthroplasty. A post-operative CT scan using the low dose Imperial knee protocol was obtained as well and analysed with 3D reconstruction software to measure the true values of these parameters. The accuracy and spread of the pain radiographic measurements were then compared with the values obtained on the CT.

On the femoral side, the mean angle in coronal alignment was 1.5° varus (Range 3.8, SD 1, min 0.1, max 3.9), whereas the mean angle in sagittal alignment was 8.6° of flexion (Range 7.5, SD 1.5, Min 3.7, Max 11.2). The true values measured with CT were 2.4° and 11.0° respectively. As for the tibial component, the mean coronal alignment angle was 89.7° (Range 11.6, SD 3.3, Min 83.8, Max 95.4), and the mean posterior slope was 2.4° (Range 8.7, SD 1.6, Min -2, Max 6.7). The CT values for these were 87.6° and 2.7° respectively.

We conclude that the plain radiographic measurements had a large scatter evidenced by the wide ranges in the values obtained by the different observers. If only the means are compared, the plain radiographic values were comparable with the true values obtained with CT (that is; accuracy was good) with differences ranging from 0.3° to 2.4°. The lack of precision can be avoided with the use of CT, particularly with the advent of low-dose scanning protocols.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 6 | Pages 738 - 744
1 Jun 2009
Hart AJ Sabah S Henckel J Lewis A Cobb J Sampson B Mitchell A Skinner JA

We carried out metal artefact-reduction MRI, three-dimensional CT measurement of the position of the component and inductively-coupled plasma mass spectrometry analysis of cobalt and chromium levels in whole blood on 26 patients with unexplained pain following metal-on-metal resurfacing arthroplasty.

MRI showed periprosthetic lesions around 16 hips, with 14 collections of fluid and two soft-tissue masses. The lesions were seen in both men and women and in symptomatic and asymptomatic hips. Using three-dimensional CT, the median inclination of the acetabular component was found to be 55° and its positioning was outside the Lewinnek safe zone in 13 of 16 cases. Using inductively-coupled plasma mass spectrometry, the levels of blood metal ions tended to be higher in painful compared with well-functioning metal-on-metal hips.

These three clinically useful investigations can help to determine the cause of failure of the implant, predict the need for future revision and aid the choice of revision prostheses.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 49 - 49
1 Mar 2009
Kannan V Cobb J Richards R Nakhla A
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INTRODUCTION: Periprosthetic bone remodeling after uncemented hip replacement has always been a matter of research and debate. DEXA analysis of BMD was studied by previous groups but not the cross sectional cortical volume. We report a validated CT based algorithm for accurate measurement of cortical volume in these group of patients.

METHODS: Twenty two patients (34 hips) who have undergone Uncemented Furlong total hip replacement agreed to undergo CT scan of their hips for our study. The mean age was 74.6 yrs. The mean follow up was 5.4 yrs. 12 patients had bilateral replacement.

Using software adapted for the specific purpose, femoral cortical volume was measured at three different levels at a fixed distance from the lower border of the lesser trochanter on both sides: 6mm distal to the tip of the prosthesis (z), At the top of the cylindrical portion(x) Midway between x and z (y).

Accuracy and precision of the of the method was also assessed.

RESULTS: The mean cortical volume in the proximal cylindrical portion (x), midpoint(y) and the portion of bone distal to the prosthesis (z) were 458 mm3, 466 mm3, 504 mm3 respectively. The corresponding cortical volumes in the contralateral native femur in unilateral hip replacements were 530 mm3(x), 511 mm3(y), 522 mm3 (z) giving a ratios of 0.86(x), 0.91(y) and 0.97(z). The mean cortical volumes on the left side of bilateral hips were 490 mm3(x), 499 mm3(y) and 528 mm3 (z). The mean cortical volumes on the right side were 456 mm3(x), 463 mm3 (y) and 516 mm3 (z).

No significant trend was noted with change of volume of bone with time.

In the three cases who had cemented hips on their other side, the cemented hips exhibited substantially more stress shielding than their cementless controls (ratios of 0.82, 0.74 and 0.85).

A high correlation between the test and standard measurements was noted. The interobserver agreement between two observers was also good.

DISCUSSION & CONCLUSION: In a fully coated uncemented femoral component, with documented long term results, it is to be expected that load will be shed steadily along the length of the prosthesis. In this study we have confirmed this supposition, with volumetric data, by showing that an almost normal bone just below the tip of the stem (97% volume) reduces to a bone volume of 91% by the middle of the stem and then 86% by the shoulder of the prosthesis. This decrease in the volume of cortical bone effectively normal at the tip of the prosthesis while not optimal appears to stabilize early with no trend of continued reduction over a decade. The effect of cementation on stress shielding was only examined incidentally in this study but appears to contribute to more marked bone loss.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 46 - 46
1 Mar 2009
Iranpour F Cobb J Amis A
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Introduction: The normal relationships of the patellofemoral joint provide a basis for the evaluation of patients with patellofemoral abnormalities. Previous studies have often described the patellofemoral joint using X-rays which are encumbered with projectional inaccuracies. We have used CT to describe the geometry of this joint and its relationship to the tibiofemoral joint in terms of angles and distances.

Materials and method: 33 patients had a CT scan prior to medial unicompartmental knee replacement. These patients have minimum patellofemoral joint disease. Special software was used to convert the scans to 3D and measure the distances and angles. The flexion axis of the tibiofemoral joint was found as the line connecting the centres of the spheres fitted to posterior femoral condyles. These two centres and femoral head centre form a frame of reference for reproducible femoral alignment. The trochlear geometry was defined by fitting circles and spheres to slices and surfaces, then constructing an axis through their centres. The geometry of the patella was established by fitting two planes to the proximal and anterior extra-articular surfaces of the patella. The relationships between these planes and the rest of the patella were explored.

Results: The deepest points on the trochlear groove can be fitted to a circle with radius of 23mm (stdev 4mm) and an rms of 0.3mm. This centre is offset by 21mm (stdev 3mm) at an angle of 68° (stdev 8°) from the line connecting the midpoint between the centres of the femoral condyles and a point in the piriform fossa.

On either end of this line, the articular surface of the trochlea can be fitted to spheres of radius 30mm (stdev 6mm) laterally and 27mm (stdev 5mm) and an rms of 0.4mm medially. The centres of the circle and the two spheres fall on a line with an rms of 1.1mm.

The anterior and proximal patellar planes could be described as flat surfaces (rms of 0.4 and 0.3mm). The median ridge could be described as a straight line (rms of 0.2mm). The angle between planes was 112° (stdev 5°); the average angle between the proximal plane and the line on the medial ridge was 62° (stdev4°).

The functional centre of the patella was defined as a point in the centre of 2 planes orthogonal to the sagital plane from the midpoint between the most proximal and most distal points on the median ridge. The length, width and thickness of the patellae were measured at 22mm +/−4mm, 47mm +/− 3mm and 24 mm+/− 2 mm.

Discussion: This investigation has allowed us to characterise the patello-femoral joint geometry. The knowledge of the shapes of the surfaces of this joint and their relationships may help identify and explain the aetiology of patello-femoral dyplasia and other pathologies. It may also be of use in planning and performing joint reconstruction and may have implications for the design of patello-femoral replacements and the rules governing their position.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 561 - 561
1 Aug 2008
Boroujeni FI Amis A Cobb J
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Patellofemoral symptoms are a prominent cause of dissatisfaction following knee arthroplasty. This may relate to difficulty in knowing where to resect the bone and in placing prosthetic components to reproduce the anatomy accurately. This study developed geometrical data to facilitate these procedures during TKR.

Thirty CT scans of patients above the age of 55 without patellofemoral disease were performed. Three dimensional images were reconstructed using computer software that enabled manipulation of these images and measurements to be taken. These models allowed the shape of the patella to be modelled, its size and the track it takes in the normal trochlea.

The anterior and proximal patellar planes could be described as flat surfaces with an rms of 0.4 and 0.3mm. The angle between these planes was 112° (stdev 5°). The median ridge of the articular surface was a straight line with an rms of 0.2mm and the average angle between the anterior plane and this line was 12° (stdev4°). The angle between the anterior plane and a line fitted to the posterior aspect of the apex of the patella was 56° (stdev 2°). Having oriented the patella with the proximal plane vertical, the distal pole of the patella was within 2mm of the same sagittal plane as the median ridge of the articular surface in all cases. The functional centre of the patella was defined as a point in the centre of 2 planes orthogonal to the sagittal plane at the midpoint between the most proximal and most distal points on the median ridge. In the transverse section this centre was always on the line separating the superficial and deep surfaces of the patella. Also the length, width and thickness of the patellae were measured at 22mm +/−4mm, 47mm +/− 3mm and 24 mm+/− 2 mm. The average ratio of the lateral facet to medial facet width was 1.3 (range 0.8–1.6). The average ratio of the patellar width to thickness was 2.0 (S.D. 0.106, 95%CI 1.96 to 2.03) with a strong correlation(r= 0.89).

From this work we have concluded that the anterior and proximal planes of the patella, which will not be affected by the disease, can be defined and used as a frame of reference for the patella, which will be helpful for navigating the patella and restoring its anatomical form in the presence of erosive changes.

The patella has a constant shape, so that its articular surface can be defined in relatively simple terms, and can be referenced off its non articular surface.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 559 - 559
1 Aug 2008
Kannan V Heaslip R Richards R Sauret V Cobb J
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Wear and loosening are the major causes for long tem failure in Total Hip Replacement (THR). Accurate three dimensional wear analysis of radiographs has its own limitations. We report the results of our clinical study of three dimensional volumetric wear measurements using our custom low radiation risk CT based algorithm and special software

Twenty four patients (32 hips) agreed to take part in our study. The male: female ratio was 1:4. The mean age was 75 years and the mean follow up was 5.4 years. All patients had 28 mm diameter ceramic heads. Of the 32 hips, 17 hips had polyethylene inserts and 15 hips had ceramic inserts. The maximum follow up for the polyethylene and ceramic groups were 12 years and 5.5 years respectively. All the patients were scanned using Somatom Sensation 4 scanner. Using custom software, 3D reconstruction of the components was done and landmark acquisition done on the femoral head, acetabular metal component and the insert. From these landmarks, a dedicated program was used to calculate the centre of the femoral head in relation to the centre of the acetabular component in all three axes and an indirect measurement of wear obtained. Using the axes measurements graphical 3D models of migration of the femoral head component into the acetabular liner were created and volume of wear measured using special software. Accuracy of the method was assessed by measuring the radius of the femoral head since all patients had 28mm diameter heads implanted in them. Assessment of precision of method was done by calculating the level of agreement between two independent observers.

In the polyethylene group, there was no significant (< 1mm) wear in x and y axis with time. However there was significant evidence of wear in relation to time in the z axis (max wear = −2.5 mm). In the ceramic group with relatively shorter follow up, there was no evidence of significant wear in all three axes. The mean volume measured in the polyethylene group was 685 mm3 (max = 1629 mm3, min = 132mm3 ). The mean volume measured in the ceramic group was 350mm3 (max = 1045 mm3, min = 139mm3 ). The mean radius of the femoral head measured in both groups was 14.02mm (range =13.8 to 14.4 mm). Accuracy was limited by artifacts particularly in bilateral hip arthroplasties and further in the ceramic group because of the restricted access to the ceramic head for placement of markers. Measurements obtained by two independent observers showed a strong correlation (0.99, p value = 0.001) for the polyethylene group. In the ceramic group the correlation (0.69, p value=0.0126) was not as strong as the polyethylene group.

This study has produced a method for three dimensional estimation of wear that can be obtained from low dose CT scans with better accuracy and repeatability (< 0.5 mm) even than to ex vivo studies particularly in polyethylene bearings(wear rate 0.14mm/yr). Noise reduction with appropriate artefact reduction software may further improve the accuracy of this simple and repeatable method.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 565 - 565
1 Aug 2008
Kannan V Cobb J Richards R Nakhla A
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Periprosthetic bone remodeling after uncemented hip replacement has always been a matter of research and debate. DEXA analysis of bone density was studied by previous groups but not the cross sectional cortical volume. We report a validated CT based algorithm for accurate measurement of cortical volume in these group of patients.

Twenty two patients who have undergone Uncemented Furlong total hip replacement agreed to undergo CT scan of their hips for our study. The mean age was 74.6 yrs. The mean follow up was 5.4 yrs. Using software adapted for the specific purpose, femoral cortical volume was measured at three different levels at a fixed distance from the lower border of the lesser trochanter on both sides:

6mm distal to the tip of the prosthesis (z),

At the top of the cylindrical portion(x)

Midway between x and z (y).

Accuracy of the method was assessed by measuring the volume of artificial cavities created on a polyurethane pelvis. Assessment of precision of method was done by calculating the level of agreement between two observers.

The mean cortical volume in the proximal cylindrical portion (x), midpoint(y) and the portion of bone distal to the prosthesis (z) were 458 mm3, 466 mm3, 504 mm3 respectively. The corresponding cortical volumes in the contralateral native femur in unilateral hip replacements were 530 mm3(x), 511 mm3(y), 522 mm3 (z) giving a ratios of 0.86(x), 0.91(y) and 0.97(z). The mean cortical volumes on the left side of bilateral hips were 490 mm3(x), 499 mm3(y) and 528 mm3 (z). The mean cortical volumes on the right side were 456 mm3(x), 463 mm3 (y) and 516 mm3 (z). No significant trend was noted with change of volume of bone with time. In the three cases who had cemented hips on their other side, the cemented hips exhibited substantially more stress shielding than their cementless controls (ratios of 0.82, 0.74 and 0.85). A high correlation between the test and standard measurements was noted. The interobserver agreement between two observers was also good.

In a fully coated uncemented femoral component, with documented long term results, it is to be expected that load will be shed steadily along the length of the prosthesis. In this study we have confirmed this supposition, with volumetric data, by showing that an almost normal bone just below the tip of the stem (97% volume) reduces to a bone volume of 91% by the middle of the stem and then 86% by the shoulder of the prosthesis. This decrease in the volume of cortical bone effectively normal at the tip of the prosthesis while not optimal appears to stabilize early with no trend of continued reduction over a decade. The effect of cementation on stress shielding was only examined incidentally in this study but appears to contribute to more marked bone loss.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 560 - 560
1 Aug 2008
Nakhla A Turner A Rodriguez F Harris S Lewis A Cobb J
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Acetabular and pelvic fractures are amongst the most challenging to treat, still requiring major open surgery. The operations to reduce and fix them entail lengthy operative time, significant blood loss and use of ionising radiation.

We report on the initial stages of developement of a minimally invasive method for navigated reduction and percutaneous fixation of acetabular fractures (NRFA). A commercial navigation platform (Acrobot Ltd.) will be adapted for use with this technique. CT based planning will be used to identify the correct realignment of the the bone fragments, which will then be reduced percutaneously with the aid of two tracked arms attached to the navigation system. Schanz pins, which are inserted in pre-operatively planned sites in each fragment using safe trajectories, are handled as joysticks to manipulate the fracture under computer assistance. Registration of the fragments after insertion of the joysticks will be carried out by means of fluoroscopic images of the AP and Judet views of the fractured acetabulum. Once reduction is achieved by following on-screen instructions, the joysticks are held in place by a custom clamping system connected to one of the arms, while the other is used for percutaneous insertion of column screws.

This technique is potentially suitable for a number of acetabular fractures which include transverse, anterior column, posterior column, T-fractures and some associated both columns fractures. These constitute over 50% of Letournel’s and 60% of Matta’s original series of acetabular fractures. Furthermore, this percutaneous technique could reduce bleeding, wound complications, hospital stay and cost of treatment. Intra operative ionising radiation would be greatly reduced for both patients and the surgeons.

Adequate training with the use of this software may provide a greater number of surgeons the capability to surgically treat these complex fractures.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 561 - 561
1 Aug 2008
Cobb J Henckel J Brust K Gomes P Harris S Jakopec M Baena FRY Barrett A Davies B
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A Prospective, randomised controlled trial demonstrates superior outcomes using an active constraint robot compared with conventional surgical technique in unicompartmental knee arthroplasty (UKA). Computer assistance should extinguish outliers in arthroplasty, with robotic systems being able to execute the preoperative plan with millimetre precision.

We used the Acrobot system to deliver tailor made surgery for each individual patient. A total of 27 patients (28 knees) awaiting unicompartmental knee arthroplasty were randomly assigned to have the operation performed either with the assistance of the Acrobot or conventionally. CT scans were obtained with coarse slices through hips and ankles and fine slices through the knee joint. Preoperative 3D plans were made and transferred to the Acrobot system in theatre, or printed out as a conventional surgical aid. Accurate co-registration was confirmed, prior to the surfaces of the femur and tibia being milled. The outcome parameters included measurements of the American Knee Society (AKS) score and Western Ontario and McMaster Universities Osteoarthritis (WOMAC) index. These measurements were performed pre-operatively and at six, 18 weeks, and 18 months post-operatively. After 18 months two UKA out of the conventional trial (n =15) had been revised into a total knee replacement (TKA), whereas there were no revisions in the Acrobot trial group (n = 13).

Using an active constrained robot to assist the surgeon was significantly more accurate than the conventional surgical technique. This study has shown a direct correlation between accuracy and improvement in knee scores at 6, 18 weeks and 18 months after surgery. At 18 months there continues to be a significant improvement in the knee scores with again a marked correlation between radiological accuracy and clinical outcome with higher accuracy leading to better function based on the WOMAC and American Knee Society Score.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 565 - 565
1 Aug 2008
Kannan V Cobb J Richards R
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Periacetabular osteolysis is now considered one of the major long term complications following uncemented total hip replacement. Radiographs are inaccurate and lack sensitivity in detecting lesions even with multiple views. Very few clinical studies have shown the use of CTscan for measuring these lesions. We report our clinical experience with CT based algorithm for measuring it.

Twenty two patients (32 hips) who have undergone Uncemented Furlong total hip replacement agreed to undergo CT scan of their hips for our study. The mean follow up was 5.4 yrs. Of the 34 hips,17 were polyethylene bearings and 15 were ceramic bearings. Nine patients had bilateral replacement in this group. Using custom reconstruction software, 3D models were created and volume measurements made after identifying the lesions in the slices and painting them using appropriate tools available in the software.

Accuracy of the method was assessed by measuring the volume of artificial cavities created on polyurethane pelvis with and without the components. In our control experiments, a high correlation between the test and standard measurements was noted in the cavities above the component, while medial to the acetabular component in bilateral cases it was difficult to be accurate, with cavities less than 10mm in diameter being hard to detect reliably.

In our clinical group of 32 hips, degenerative cysts were noted in 13, secondary rheumatoid cysts in 2 and wear cysts were noted in 2, the largest having a maximum dimension of 10mm. All the degenerative cysts were in the peripheral zone and both the wear cysts were seen in the central zone communicating with the screw holes. These cysts were identified by the characteristic absence of sclerosis surrounding the cyst and obvious communication with screw holes. Both the wear cysts were found with polyethylene bearings at a minimum of 5yrs follow up.

The mean volume of the degenerative cysts was 799 mm3 (71–3500) and the mean volume of the wear cysts was 567 mm3 (550–585)

The low dose CT method we describe and the results we report show that cavities can be measured reliably, above or below the acetabular component. On the medial side, in bilateral cases in particular, although location is possible, volumetric analysis of anything less than 10mm in diameter is not.

Regarding surveillance strategy for wear cysts, we have established that in this series the incidence is 14%, with one at 5 yrs and another noted at 12 yrs, with 10mm in maximum dimension. The absence of any wear cysts at all in the ceramic group, albeit after a shorter follow up of only 5 years is encouraging.

Based on these figures, with these implants, we would recommend that there is no need to undertake surveillance more frequently than every 10 years.