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Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 418 - 418
1 Nov 2011
Lazennec J Rousseau M Rangel A Catonne Y
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Introduction: Computer assisted total hip replacement (THA) usually uses the anterior pelvic plane (plane of Lewinneck, APP) for reference because the anatomical landmarks are easy to access during the surgical procedure. However, a recent study shows the lack of correlation in between the Lewinnek angle in standing position (L) and the spinal radiological parameters for sagittal balance, specifically the incidence angle and the sacral slope. The anatomical variations of the anterior superior iliac spines account for the discrepancy. The authors propose here the assessment of the Lewin-nek – sacrum angle (LS) (anterior pelvic plane to the sacral endplate) Methods: 120 asymptomatic patients with THA had low dose lateral X-rays of the lumbo-pelvic area (Definium 8000, GE Healthcare ;dose 0,6 mSivert). The measurements of the sacral slope, incidence angle, and APP were done by two independent observers.

Results: The sacral slope and incidence angles were similar to other series. The APP was no clearly identified in 78 cases. The average L angle was −3° (SD 8°) in standing position, −23° (SD 11°) in sitting postion, and −2° (SD 8°) in lying position. The average LS angle was 47° (SD 13°). The geometrical relationship between the LS a ngle, the L angle and the sacral slope is reported.

Conclusion: THA stability supposes that the orientation of the acetabular component shall remain within extreme values in standing, sitting, and lying postures. The adjustment of the acetabulum takes into account the functionnal anatomy of the lumbopelvic area. The sacral slope is a reliable radiological reference and is related to the sagittal balance of the spine. The APP presents some interindividual variability and is poorly visible on the radiographs, but it is easily accessible during surgery. The author suggest using the Lewinnek sacrum (LS) angle for radiological planification and for surgical navigation procedures.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 505 - 505
1 Nov 2011
Lazennec J Rangel A Catonné Y
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Purpose of the study: The analysis of hip prostheses often remains limited to standard x-rays taken in the upright position or a CT scan taken in the supine position. The EOS® system enables imaging the entire body for head to foot in a lateral and anteroposterior views, in an upright or sitting position. The purpose of this work was to compare the standard radiographic work-up with the EOS system for the analysis of postural elements in patients with hip arthroplasty.

Material and method: This prospective study included 50 patients free of complications. The standard radiographic work-up included AP and lateral views in the upright and sitting positions. The standard then EOS imaging protocols were performed in two different locations. Images were acquired with the patients in a comfortable position: for the sitting position, the knees were flexed 90°. Two operators took measurements to be able to analyse reproducibility of the morphological parameters (incidence, sacroacetabular angle, and the positional parameters (version, sacral slope, Lewinnek angle, sagittal and frontal cup inclinations, pelvifemoral angle and orientation of the prosthetic neck on the lateral standing then AP sitting position). Pelvic rotation was determined on the AP view by comparative measurement of the projected width of the iliac wings in each pelvis. Hip extension reserve was calculated on the hyperextension lateral view.

Results: Reproducibility of position was excellent for different times and locations. Twelve hip (24%) presented significant reproducible rotation in the AP view; for eight of these hips (16%), the phenomenon disappeared in the sitting position. Four hips (8%) had pelvic rotation in the sitting position on the AP view. On the AP pelvic view in the sitting position, three patients had a femoral neck in functional retroversion while the anatomic femoral anteversion was normal on the scanner. The pelvic parameters were equivalent to those already described. The reproducibility of the measures was excellent between the standard x-rays and the EOS images with the exception of measurements involving the centre of the femoral head (incidence, pelvifemoral angle). It was easier to align the femoral axis on the EOS lateral images, particularly for additional calculation of extension reserve. The Lewinnek angle could not be measured in the sitting position in 32 hips (60%) because of insufficient resolution.

Conclusion: The overall evaluation of the pelvis and the subpelvic sector provides new information concerning the respective positions of the cup and the femur in functional situations.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 399 - 399
1 Nov 2011
Lazennec J Ducat A Sarialli H Catonne Y
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Introduction: Wear performances and fracture toughness of the alumina-matrix composite (AMC) Biolox-delta® are pointed out in the literature. Clinical and radiological studies are needed to assess the potential benefits of AMC/AMC bearing surfaces. The aim of this study is the prospective evaluation of complications and risk factors in patients implanted with AMC liners and 32–36 mm AMC femoral heads.

Methods: 323 consecutive patients were included prospectively since 2006.

243 were implanted for primary surgery with 32 or 36 mm ball heads for a 10–12, 6° tapers.

In 80 cases, we used 32 and 36 mm Delta® sleeved heads (M,L,XL) for the adaptation on 12–14,5°43 tapers or 10–12, 6° tapers (acetabular revisions in absence of stem exchange, or to increase the lenght of the femoral neck and the offset) All the clinical and radiological files were evaluated at a minimum 2 years follow-up with a special attention for the fracture risk and squeaking. Radiological data were analysed using Dicomesure® software.

Results: We did not face any significant problem in this series. No fracture occurred. No abnormal wear or implants migration could be detected. We did not observe squeaking phenomenons. 2 THP were revised for septic complications ; the retrivials were analysed for transformation studies(Xray diffraction method XRD). The phase transformation tetragonal to monoclinic was mild, in accordance with previous experimental data.

Conclusion: The limitation of this study is its short follow-up; nevertheless the clinical results are in accordance with the previously published experimental data.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 475 - 475
1 Nov 2011
Masson B Lazennec J Fisher J Jenning L
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Dislocation remains one of the most common complications after total hip arthroplasty.

Precise cup position appears to be a main factor as significant variations occur for frontal and sagittal acetabular tilt and anteversion according to sitting or standing positions.

An innovative dual mobility ceramic-on-ceramic joint has been developed to solve these problems.

The dual mobility ceramic-on-ceramic joint allows to move the rotation center much deeper inside the insert in order to increase the joint stability without negative impact on the ROM. This device revealed higher torques against subluxation in comparison to the classical Al-Al systems, even with 36mm head diameters, or 41 mm metal on metal bearings.

The additional outer-bearing surface motion creates a second “adjustable acetabulum” due to the eccentration between the rotation center of the ball head and the rotation center of the bipolar head. This offset creates a resultant force that rotates the bipolar component.

Using two bearing ceramic surfaces, the intermediate component acts as a “self adjusting cup”, dealing with the variations of pelvic orientation and acetabulum anteversion.

The use of the dual mobility ceramic-on-ceramic joint seems an interesting alternative when facing difficult or unexpected situations for cup adjustment and cases with hip instability In a hip simulator in micro separation condition, the wear of the dual mobility ceramic-on-ceramic was less than 0.01 mm3/million cycles, the detection limit for wear measurement. There was no change in the surface roughness of the inserts.

The design of the joint with the mobile ceramic head prevented edge loading of the head on the edge of the cup. No stripe wear was observed.

Since 2006 more than 2000 dual mobility ceramic-on-ceramic systems have been implanted in Europe and clinical studies are conducted. The aim is to demonstrate the resistance to dislocation in primary total hip arthroplasty. Previous results over 125 patients in a prospective multicentric study show a Harris and Womac score equivalent to a standard hip prosthesis. No dislocations have been reported. No ceramic breakage or “squeaking” phenomenon appears.

Dislocation and microseparation are major causes of failure for ceramic-ceramic hip prosthesis. When no ideal solution has been found for acetabular implantation, the dual mobility ceramic-on-ceramic device is a real alternative. The exclusive design of the bipolar head give the high resistance to wear and stripe wear to the dual mobility ceramic-on-ceramic joint. Reducing the risk of dislocation and reducing wear drastically are two advantages that can place the dual mobility ceramic-on-ceramic joint as the best choice in primary Total Hip Arthroplasty. Obviously this choice applies to recurrent dislocation also.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 435 - 435
1 Nov 2011
Catonné Y Khiami F Ali HS Lazennec J
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Introduction: In patients with gonarthrosis secondary to a femoral or a tibial mal union, the technical problems are different according to the localization and the importance of the deformity, the presence of boneless, the cutaneous and ligamenteous status and the degree of preoperative motion.

Material and Methods: Between 1995 and 2003, 34 TKR have been performed in patients with mal unions either post trauma (26 cases) either secondary to surgery (osteotomy with hypercorrection). There were 21 males and 13 females. The average age was 63 years (38 to 77) The mal union was localized to the femur (9 cases) or the tibia (23 cases) or to the both femur and tibia (2 cases). The deformity was variable : varus, valgus, flessum, recurvatum or rotationnal mal union. IKS scoring, HKA, MFA and MTA angles were evaluated pre and post operatively. 11 cases of intra articular mal unions, secondary to epiphyseal fractures were operated : a TKR posterostabilized (9 cases) or constrained (2 cases) was performed.

In the extra articular mal unions (23) the technique depended on the degre of intraosseous deformity : medial or lateral release or osteotomy performed when the intra osseous deformity was more than 10°. TKR was associated with an osteotomy in one time surgery in 5 femoral mal unions and 12 tibial deformities.

Results: The average follow up was 8 years (4 to 13 years). Complications consisted in 5 phlebitis, 2 superficial skin necrosis, 4 stiff knees (flexion less than 80°). There was no infection in this short serie. The average IKS score was 65 before and 163 after operation. The average flexion was 83° preoperatively and 98° after surgery. Average HKA angle was 167° pre and 182° post operatively in the varus deformities. In the valgus deformity it was 191° pre and 181° post surgery.

Discussion: Average IKS scoring is less good in post traumatic mal unions than in the habitual TKR specially because of the motion : the knee is often stiff preoperatively and remain often stiff postoperatively. A quadriceps release is sometimes indicated either during the TKR either in a second time. Constrained implants (constrained condylar knee or rotating hinge) are necessary in some cases of medial or lateral insuffisency of the collateral ligament.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 535 - 535
1 Oct 2010
Catonné Y Khiami F Lazennec J Sariali H
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Introduction: In patients with gonarthrosis secondary to a femoral or a tibial mal union, the technical problems are different according to the localization and the importance of the deformity, the presence of boneless, the cutaneous and ligamenteous status and the degree of preoperative motion.

Matériel et méthodes: Between 1995 and 2003, 34 TKR have been performed in patients with mal unions either post trauma (26 cases) either secondary to surgery (osteotomy with hypercorrection).

There were 21 males and 13 females. The average age was 63 years (38 to 77)

The mal union was localized to the femur (9 cases) or the tibia (23 cases) or to the both femur and tibia (2 cases). The deformity was variable : varus, valgus, flessum, recurvatum or rotationnal mal union. IKS scoring, HKA, MFA and MTA angles were evaluated pre and post operatively. 11 cases of intra articular mal unions, secondary to epiphyseal fractures were operated : a TKR posterostabilized (9 cases) or constrained (2 cases) was performed.

In the extra articular mal unions (23) the technique depended on the degre of intraosseous deformity : medial or lateral release or osteotomy performed when the intra osseous deformity was more than 10°. TKR was associated with an osteotomy in one time surgery in 5 femoral mal unions and 12 tibial deformities.

Results: The average follow up was 8 years (4 to 13 years). Complications consisted in 5 phlebitis, 2 superficial skin necrosis, 4 stiff knees (flexion less than 80°). There was no infection in this short serie. The average IKS score was 65 before and 163 after operation. The average flexion was 83° preoperatively and 98° after surgery. Average HKA angle was 167° pre and 182° post operatively in the varus deformities. In the valgus deformity it was 191° pre and 181° post surgery.

Discussion: Average IKS scoring is less good in post traumatic mal unions than in the habitual TKR specially because of the motion : the knee is often stiff preoperatively and remain often stiff postoperatively. A quadriceps release is sometimes indicated either during the TKR either in a second time. Constrained implants (constrained condylar knee or rotating hinge) are necessary in some cases of medial or lateral insufficiency of the collateral ligament.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 523 - 523
1 Oct 2010
Lazennec J Catonné Y Gorin M Marc AR
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Introduction: Hip dislocation remains a relevant complication of total hip arthroplasty.The implants position plays a major role, especially cup anteversion.It has been demonstrated that anteversion measured on CTscan depends on the pelvic position in a lying patient. This prospective study evaluates the influence of pelvic tilt according to standing and sitting positions.

Material and Methods: The radiological records of 328 consecutive asymptomatic patients with THP were analyzed. These were routine radiological controls of non cemented THP with metal back acetabular implants. All patients had AP and lateral radiographs in standing and sitting position and a “low-dose” CT scan of the pelvis in lying position.Patients were checked for the absence lower limb length discrepancy and lumbosacral junction abnormality.

All the measurements were done by two independent observers and averaged. From the standard radiographs, the sacral slope (SS), the acetabular frontal inclination (AFI), and the acetabular sagittal inclination (ASI) were measured in standing, sitting, and lying positions.

From the CT scan sections, the anatomical ante-version (AA) was measured in lying position on axial images according to Murray. The results were compared to a previously described protocol replicating standing and sitting positions: CTscan sections were oriented according to sacral slope.

Results: We confirmed that the anatomical anteversion (AA), the frontal inclination (FI), and the sagittal inclination (SI) were functional parameter which significantly varied between standing, sitting, and lying positions according to sacral slope variations.The acetabular parameters in lying position highly correlated to the one in standing position, while poorly correlated with sitting position. The difference between the lying and the sitting positions was about 10°, 25°, and 15° for the AA, the AFI, and the ASI respectively.Mean lying anteversion angle was 24.2° (SD6,9°).Posterior pelvic tilt in sitting position, (sacral slope decrease) was linked to anteversion increase (mean value 38,8° - SD 5,4°). Anterior pelvic tilt in standing position (sacral slope increase) was linked to lower anteversion (mean value 31,7° - SD5,6°).

Discussion and Conclusions: Our study confirms the interest CTscan sections oriented according to sacral slope.The strong correlation between lying and standing measurements suggests that classical CTscan protocol is relevant for standing anteversion. According to the poor correlation between lying and sitting positions, it is less contributive for the investigation of dislocations in sitting position.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 358 - 358
1 May 2010
Sariali E Lazennec J Catonné Y
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Introduction: The goal of the study was to analyse the modification of the sagittal lombo-pelvic equilibrium after total hip replacement for osteoarthritis.

Materials and Methods: The sagittal lombo-pelvic equilibrium was analysed among 89 patients who underwent total hip replacement for osteoarthritis, using lateral X-rays of the whole spine including the hips performed pre-operatively and at one year post-operatively. Reference values were calculated by carrying out the same analysis among 100 asymptomatic healthy volunteers. The studied parameters were: the sacral tilt (ST), the pelvic version (PV) and the sacral incidence (SI).

Results: The mean pre-operative value of STangle was significantly lower in the osteoarthritis group (20.6° +/−6) compared to the reference group (39.4 +/6, p< 0,00001). The mean pre-operative value of VP angle was significanlty higher in the osteoarthritis group (31°+/−8) compared to the reference group (13.5 +/−6 p < 0,00001). There was no significant difference between the two groups for the sacral incidence (p=0,3). At one year post-operatively, the sacral tilt has significantly increased by 5.5° (p< 0.00001).

Discussion: Compared to asymptomatic healthy volunteers, patients affected by osteoarthritis had a pelvic retroversion that has decreased post-operatively but still remained lower than the norm.

Conclusion: The lombo-pelvic equilibrium is different in case of osteoarthritis. After total hip replacement the pelvis remained retroverted. This phenomenon should be taken into account for the planning of total hip arthroplasty.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 170 - 170
1 Mar 2010
Lazennec J Sariali H Rousseau M Rangel A Catonné Y
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Hip-spine relationships should be better investigated in THP as lumbo-sacral orientation in the sagittal plane plays a critical role in the function of the hip joints. Lateral X-rays showing spine and hips together in standing, sitting or squatting positions characterize the adaptations of the sagittal balance and the functionnal interactions between hips and spine.

Acetabular cup implantation has to be planned for frontal inclination, axial anteversion, and sagittal orientation. The later refers to the sacro-acetabular angle, key-point in the spine – hip relationships, and that is redefined by the surgeon at the time of implantation.

Usual standard CT-sections are biased for evaluating acetabular anteversion. The conventional CT procedure does not refer to the pelvic bony frame and. the measured anteversion is a projected angle on a transverse plane, depending on the pelvic adaptation in lying position. This measured angle is often considered as anatomical anteversion, leading to some confusion. Therefore this angle is only a “functional” supine anteversion, reflecting the anterior opening angle of the acetabulum in a specific position. According to the sagittal orientation of the pelvis, the true functional acetabular orientation can virtually be assessed in various postures from adjusted CT-scan sections.

The EOS low irradiation 2D-3D X-ray scanner is an innovative technology already used for global evaluation of the spine. This technology allows simultaneously “full body” frontal and lateral X-rays with the patient in standing, sitting or squatting positions; a tridimensionnal patient specific bone recontruction can be performed and the cup anteversion can be directly assessed according to the position.

We investigated the lumbo-pelvic parameters influencing the tridimensionnal orientation of the acetabulum. We compared the data obtained for real postural situations using the EOS system and the measures from plane X Rays and classical CT scan cuts replicating standing, and sitting positions.368 patients with cementless THP were involved in a prospective follow-up protocol. Sacral slope and pelvic tilt, incidence angle, acetabular frontal and sagittal inclination were evaluated on AP and lateral standard XRays. Functionnal anteversion of the cup has been measured using a previously described protocol with CTscan cuts oriented according to standing and sitting sacral slope. The mean difference between CTscan and EOS system was 4,4° with comparable accuracy and reproductibility.

Sacral slope decrease in sitting position was linked to anteversion increase (38,8° SD 5,4°). Sacral slope increase in standing position was linked to lower ante-version (31,7° SD 5,6°). The anatomical acetabular anteversion, the frontal inclination, and the sagittal inclination were functional parameter which significantly varied between the standing, sitting, and lying positions. We noticed that the acetabular parameters in lying position highly correlated to the one in standing position, while poorly correlated with the one in sitting position. The difference between the lying and the sitting positions was about 10°, 25°, and 15° for the cup anteversion (CA) and the frontal and sagittal inclinations (FI,SI) respectively. The poor correlation between the lying and sitting positions suggests that the usual CT scan protocol is biased and not fully appropriate for investigating the cases of posterior THP dislocation and subluxation, which happen in sitting position. On the contrary, a strong correlation was observed between lying and standing measurements with all the acetabular parameters (CA,FI, SI), suggesting that the classical CT assessment of the cup anteversion remains an interesting source of information in case of anterior THP

Each patient is characterized by a morphological parameter, the incidence angle. High incidence angle is linked to low acetabular anteversion, increasing the instability risk and anterior impingement in sitting and squatting position; higher anteversion angles are observed in low incidence angle patients, leading to more internal rotation of the hip in any position.

Lumbo-sacral orientation in the sagittal plane influences the tridimensionnal orientation of the acetabulum, especially for anteversion. Aging of the hip-spine complex is linked to progressive pelvic posterior extension. Impingement phenomenons, orientation of stripe wear zones and some instability situations can be interpreted according to those data.

This study points out the opportunity to adjust the CT scan sections to the sacral slope in functional position for properly investigating the orientation of the acetabular cup, mainly in case of posterior dislocation.

In addition, the mobility of the lumbo-sacral junction could be a crucial parameter in the mechanical functioning and the stability of a THP due to its impact on sacral slope and pelvic tilt. Therefore we also recommend doing dynamic lateral radiographs of the lumbo sacral junction in standing and sitting position for planning a THP implantation in order to detect stiff lumbosacral junction or sagittal pelvic malposition.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 146 - 146
1 Mar 2010
Kubo K Clarke I Lazennec J Catonne Y Smith E Halim C Yamamoto K Donaldson T
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While there are many variation laboratory and clinical studies using metal-on-metal (MOM) bearings after introduction of the 28mm MOM THR in 1988, the mapping of wear phenomena in such retrieval cases has been mimimal. In laboratory study, 28mm MOM bearing’s wear-rate was low with “run-in” and “steady-state” than large diameter MOM without theory of fluid-filum lubrication. In clinical results were not superior to the same way of laboratory study. We present a detailed analysis of 33 retrieved MOM hip bearings with 1–11 years follow-up,

We compiled 33 retrieval cases (MetasulTM: Zimmer/CenterPulse Inc., Austin, TX) including clinical information, ion concentrations from ball diameters, cup designs and stripe wear damage. The bearing surfaces were mapped using reflected light microscope (RLM), white light interferometer (Zygo Newview 600, Zygo.) and SEM(XL-30 FEG). Wear maps were constructed according to types of surface wear identified.

Patients ranged from 36 to 76 years of age (Means: 56.9 years); 54% were males. Main causes for revision were progressive radiographic lines around the cups, osteolysis and pain. The 28mm ball diameter was used in 86% of cases (largest = 52mm ball). The CoCr liner incorporated a polyethylene adaptor in 75% of cases. Cup diameter > 50mm was present in 75% of cases. Eight femoral stems were recovered and all showed major impingement marks around the neck and five also had a metallosis (Mode-4A). Stripe wear was evident on 71% of CoCr balls with medial stripes twice as common as lateral. Stripe wear was identified in 25% of CoCr liners and extended 25–160° circumference around the liners. Clear liner rim damage was present in 10 (30%) and 3 demostrated severe damage of polyethelene adaptors.

There are many limitations to such retrieval studies. These data are biased to cases that failed due to hip pain, radiographic signs of progressive osteolysis and some with high levels of metal ions. There was also the bias of having predominantly a CoCr sandwich design (polyethylene adaptor in 75% of cases). In early 1980s, the thin walled UHMWPE cup was introduced and used larger diameter balls for decreased risk of dislocation. However, unfortunally these big-ball cups produced significant PE wear debris, and diameter trends were returned to the Chanley’s small-ball paradigm again. In the same time (late of 1980’s), these second-generation MOM (28,32mm) was introduced for low wear characteristics alternate THR bearings, with sacrificing of joint stability and motion range. However, use of the small ball added well-known risks of impingement, subluxation and dislocation with rigid cups. In this study, using the ‘damage modes’ from McKellop, normal mode-1 wear occurred in only 14% of cases whereas modes 2–4 had an incidence approaching 30% each and signs of cup impingement were evident in 64% of cases. Thus summarizing MOM wear phenomena in “small” 28mm sandwich cup designs, there was retrieval evidence showing that damage modes 2–4 likely placed these patients at risk for adverse wear effects.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 114 - 114
1 Mar 2010
Lazennec J Sariali H Boyer P Rangel A Catonné Y
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Anterior approaches have been suggested for THP revision in order to reduce dislocation rate. However, the exposure is considered to be more strenuous. The goal of the study was to evaluate if anterior approach in lateral position may improve the exposure.

From 2005 to 2007, 47 patients underwent THP revision, 34 times on the acetabular side, 2 times on the femoral side and 11 patients had a bipolar revision. Mean age was 64 years and mean BMI was 23. Patients were positioned on the lateral side and had an antero-lateral approach. During the femoral procedure, the leg was placed in a sterile bag stuck on the lateral side in order to optimize the exposure by positioning the femur in adduction and posterior translation.

Acetabular and femoral exposures were achieved correctly in all the cases allowing to perform all the revisions using this technique and no additional approach was needed in any patient. Antero-posterior femorotomies were performed in 7 patients for stem replacement and cement extraction, without any specific complication. Early post-operative anterior dislocations occurred in 2 patients who underwent monopolar cup revision. Dislocation was explained by an excessive anteversion of the remaining stems. 2 patients had an incomplete and transitory sciatic deficiency due to excessive posterior translation of the femoral head in the sciatic notch.

Using this technique, THP revision seems to be achievable even in complicated cases requiring stem revision and femorotomy. Dislocation rate was low; however a larger cohort is needed to confirm these preliminary results.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 113 - 113
1 Mar 2010
Catonné Y Boyer P Abdeloumene A Lazennec J
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The new technology using femoral heads with sleeves allows conservative procedures for revision hip arthroplasty. The implantation of classical ceramic heads on a previously used femoral taper is not recommanded. When there is no loosening of the femoral implant, the use of sleeves is a good solution for using an alumine on alumine couple, specially in young and active patients.

Material and methods: 25 hips in 25 patients were included. In 12 cases the cause of revision was an acetabular osteolysis with or without loosening in metal on metal cimented THR.

In 13 patients the revision was performed for a loosening and a wear of the PHE cup with osteolysis (4 zyrcon and 9 chrome-cobalt heads). The mean age was 49 years for the metal on metal revisions (36 to 75) and 54 years for the prosthesis using a polyethylen socket.

Cementless cups were implanted using XLW delta alumina inserts. The 32 mm delta alumina sleeved heads were adjusted on the existing femoral 12–14 tapers. Patients were evaluated preoperatively and followed-up with clinical and radiological examinations.

Results: At 2 years mean follow-up, average Harris Hip Score was significantly improved (97 vs 54, p< 0.05). We did not observe ceramic fracture or squeaking. The radiographic results did not demonstrate acetabular loosening, osteolysis, or femoral abnormalities.

Concerning the metal on metal revisions, the aseptic loosening of the socket was combined with high rates of cobalt and chromium serum levels. Mean delay before revision was 4 years (2 to 11). Unipolar acetabular revisions were only decided after a carefull inspection of the remaining stems to detect any taper alteration or impingement lesions.

Postoperative cobalt and chromium serum levels significantly decreased postoperatively.

Concerning the metal on PHE and the zyrcon on PHE revisions, the mean delay before revison was 11 years (4 to 21).

At this short follow up, we did not notice any parasitic impingement due to the additional sleeve or any ceramic fracture or squeaking. The radiographic results did not demonstrate acetabular loosening, osteolysis, or femoral abnormalities.

Discussion: Failures of metal-on-metal or metal on PHE hip arthroplasties raise new technical problems. Conversion to ceramic on ceramic has been suggested in case of hypersensibility reactions or high rate of serum metal ions, and in case of osteolysis in young population. This prospective study evaluates a revision strategy using ceramic cups and delta ceramic heads with titanium adapter sleeves when a femoral revision is not required. Despite the limitation due to short follow-up, this technical option should be considered when wear surfaces exchange is decided.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 132 - 132
1 Mar 2010
Lazennec J Pascal-Mousselard H Ricart O Rakover J Rousseau M Aaron A
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Current total disc prostheses are 2- or 3-pieces devices, including 1 or 2 bearing surfaces, and providing 3 or 5 degrees of freedom but with no, or very little, resistance. The ESP® is a one-piece deformable implant made of silicon and polycarbonate polyurethane elastomer securely fixed to titanium endplates. It allows limited rotation and translation with elastic return. This cushion without fixed rotation center achieves 6 degrees of freedom including shock absorption. An earlier attempt to use elastomers (Acroflex®) failed clinically due to the polymer. This highlights the need for accurate in-vitro fatigue testing and clinical evaluations.

In-vitro fatigue testing with more than 40 millions cycles were performed on different samples for compression, flexion-extension bending, lateral bending, torsion and shear. A prospective trial was initiated in 2004 for L3L4, L4L5 and L5S1 levels. Total disc replacements have been performed in 153 lumbar levels through extra-peritoneal mini-invasive anterior approach.

After in-vitro testing, microscopic examination showed that the polymer core remained unchanged without evidence of cracking or other degradation. Gravimetric analysis revealed insignificant changes in weight. The geometrical characteristics and the cohesion of the implants remained stable. After 3 years clinical experience, there was no device related complication, except one early revision for a post-traumatic implant migration. VAS and ODI scores improvements were equivalent to other published series.

In-vitro fatigue testing and short term results of the innovative ESP® prosthesis demonstrate the reliability of the concept. The results are equivalent to other series with conventional implants.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 234 - 234
1 Jul 2008
ROUSSEAU M LAZENNEC J SAILLANT G
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Purpose of the study: PEEK (polyetheretherketone)is increasingly used for spinal fusion since its elasticity modulus is close to that of cancellous bone. This favors harmonious force distribution within and around the implant and thus stimulates bone healing by remodeling. The purpose of this work was to report the mid-term radiographic outcome with this material used for sagittal correction.

Material and methods: Fifty-seven patients aged 54.6 years on average were reviewed 4 to 8 years after isolated intervertebral fusion for degenerative disease. Levels varied from L2L3 to L5S1. Posterior instrumentation used a rigid or semi-rigid pedicle screw-plate configuration associated with an anterior approach to install a lordozing intersomatic PEEK cage and a cancellous autograft. Six patients were overweight. Regional lordosis was unchanged postoperatively for 47 patients but increased 8.2° on average for ten. The clinical outcome and radiographic fusion were noted using the Brantigan classification. Multivariate analysis was used to search for correlation between regional sagittal correction at last follow-up and the following variables: age, body weight, level, quantity of intersomatic autograft as assessed by CT, rigidity of the posterior instrumentation, posterior regional correction and size of the cage.

Results: The clinical outcome was excellent for 24 patients, good for 25, fair for 6 and poor for 2. Mean sagittal correction was decreased in 13 (5.6° on average). Multivariate analysis demonstrated a significant correlation (p< 0.01, R2=0.590) between loss of correction and the following variables: degree of initial correction, rigidity of the posterior instrumentation, age, lower level, size of the cage.

Discussion and conclusion: Despite the excellent rate of fusion, sagittal correction of the regional lordosis did not persist over time and tended to return to the initial state irrespective of the patient’s weight or the quality of the initial graft. A rigid posterior instrumentation should be considered in parallel with the effect of the PEEK for explaining its role in the loss of correction.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 78 - 78
1 Mar 2006
Catonné. Y Nogier A Lazennec J Saillant G
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This preliminary study concerns the results of THR using a minimally invasive computer assisted technique: We use the Siguier and Judet procedure. The patient is in supine position and we use an orthopedic table. The skin incision is 6 to 8 cm long and we dont cut any muscle during the approach.

The first 30 cases are studied: The navigation system is scanner free and allows different controls: cup inclination and anteversion, center of rotation, laterality, lengh of the lower limb.

The acetabular implant is a cementless impacted cup and the femoral implant is either cemented or cementless.

The first results are rapported and the technical modifications are descreibed.

A randomized study of 50 patients with CAS and 50 without CAS is now begining to determine if the risk of bad positionning the implants in MIS decreases when we use computer assisted surgery.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 104 - 104
1 Apr 2005
Sofia T Lazennec J Saillant G
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Purpose: Transverse fractures of the upper part of the sacrum are exceptional (3–5% of sacral fractures). The neurological implications are serious: loss of the anatomic relation between the pelvic girdle and spine.

Material and methods: We reviewed the cases of 50 patients treated between 1997 and 2001 (31 women, 19 men, mean age 31 years). Most of the patients had fallen from windows (n=46) and many had multiple injuries (n=38). There were 31 associated spinal fractures (18 L1 fractures). The Roy Camille classification was: type I (n=6), type II (n=34),and type III (n=20) with involvement of the pelvic girdle in 30, especially for type II and III (3 Tile A, 10 Tile B, 17 Tile C). Neurological lesions were observed in 42 patients: ten patients had paraplegia (seven total, three partial), 38 had L5 and/or S1 radicular pain, and 36 presented perineal involvement. Functional treatment was given in 11 patients (including five with neurological involvement and serious cutaneous lesions). Surgery was performed early in 25 patients (three with no deficit, 22 with neurological deficit), and late (one month) after callus formation in 14 (13 with neurological deficit, 1 for a cutaneous indication).

Results: Mean follow-up was nine years. The gravity of the pelvic injury corresponded with the degree of associated neurological deficit. Incomplete functional recovery was observed in three patients given functional treatment. For patients undergoing early surgery, ten achieved functional recovery (six total and four partial) with no case of aggravation. Surgery after formation of a callus was followed by total functional recovery in three and partial recovery in six. Surgical complications included infection (n=9) and cerebrospinal fluid fistula (n=2) which resolved after re-operation. Progress in surgical techniques (subtraction osteotomy, better stabilisation) has improved the mechanical results.

Discussion and conclusion : Analysis of these fractures must consider the frontal and sagittal planes to determine the degree of pelvic girdle involvement. The final outcome depends on the time to surgical treatment (particularly for type II and III fractures) and reconstitution of the sagittal alignment of the spine with the pelvis.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 134 - 134
1 Apr 2005
Lazennec J Gorin M Roger B Saillant G
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Purpose: Uncertain position of the acetabular implant has been the cause of dysfunction in certain cases of total hip arthroplasty (THA). Classical computed tomographic analysis of anteversion has certain limitations. Integrated reconstruction of positions at risk allows a better diagnostic approach.

Material and methods: We studied 46 THA because of posterior malposition (n=17, anterior subluxation in the standing position in twelve, and true dislocation in five) and anterior malposition (n=29, posterior subluxation in sixteen and true dislocation in thirteen). Two groups of 70 naïve hips and a group of 56 THA with no functional problem served as controls. The position of the acetabulum was studied on optimised computed tomography slices reconstructing the planes of analysis for the standing, sitting and reclining positions. The reference planes for the slices was given by the sacral tilt angle measured on the lateral views of the patient in the corresponding positions. The optimised computed tomographic measurements of anteversion were compared with the classical measures. None of the patients had abnormal femoral anteversion and/or an oblique pelvis and/or leg length discrepancy greater than 10 mm. The frontal inclination of the acetabular implants was 40°–50°.

Results: In the naïve hips, acetabular anteversion varied: 19.2 with the conventional method, 15.7 in the standing position and 31 in the sitting position. In the THA controls, anteversion measurements differed: 21.3 with the conventional method, 21.4 in the standing position and 35.8 in the sitting position. In the THA with a posterior malposition, 18/29 could not be explained by the conventional measurement, but the optimised measurement enabled an understanding in 17 hips (defective anteversion in the sitting position).

Discussion: Changes in pelvis orientation between the sitting and standing positions modifies real anteversion of the cup. In particular, subjects with THA tend to have a spontaneous posterior tilt of the pelvis related to trunk ageing. This element should be taken into account for the analysis of both major and minor THA dysfunction.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 212 - 212
1 Mar 2004
Lazennec J Saillant G
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Introduction Infection of posterior instrumentation supposes a severe failure in long arthrodeses with a demineralized skeleton.

Materials and methods From 1998 to 2002, ten patients of 19 to 76 years (mean 56 years) have been grafted with anterior Peek cages filled with autograft.

Four cases of scoliosis were operated as an average 5 times by posterior approach (3 – 9 times), all of them suffered fistulised non-unions recidivating after every one of the previous operations. 4 times the germ xas a Staph. Aureus Met. resist (1 associated with a streptococcus and 2 of them with an enterococcus). Three patients presented severe radicular pain.

Six posttraumatic cases underwent a surgical extraction of the posterior instrumentation. All of them presented a non-union with total loss of the initial angular correction. In one case the septic destabilisation affected the level proximal to the fixation. The germ responsible was every time a Staph. Aureus Met. Res. with an enterococcus associated in one of the cases.

Two inveterate fistulae were operated before. The grafts were performed on 1 to 4 levels without a new posterior fixation but in one case (5 thoracolumar approaches, 5 on lumbosacral fusions, external support by a 3 points corset between 4–6 months). The postoperative antibiotherapy has been maintained for 4 months in average (3–12 mos). The fusion was appreciated by the graft aspect on CT scan with a mean follow-up of 22 months (12 months minimum).

Results: No anterior infection has been observed, but in one post-traumatic case with a violation of the discal space by a screw. (Flare-up of the infection without anterior collection, treated by a new posterior approach with definitive kyphotic fusion as a result). All the nine others fused with clinical improvement (sevrance of the rigid corset and decreasing analgesic doses in a mean time of six months) and without significant correction loss. Three cases of radicular pain improved too. As a complication, one female patient previously operated three times by an anterior approach, was operated a new by a minimal left approach without incidents. She suffered in the postoperative period an ureteral necrosis needing a secondary nephrectomy.

Conclusion This strategy of intersomatic graft is a recovering solution in the mechanical failures of severe and reccurrent infections, often germs association. With these severe deformities on aged patients this technique is more difficult. The positive culture of disc material is a bad prognostic factor. In case of previous anterior approach, it is a good procedure the catheterisation of the ureteral duct to prevent a possible necrosis. The intersomatic cage has been a safe procedure assuring a primary and late stability in those patients with a deficient bone-stock. The cages did not induced any additionnal septic problems.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 51 - 51
1 Jan 2004
Lazennec J Fourniols E Saillant G
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Purpose: Infection of a posterior fixation can lead to a therapeutic dilemma, particularly if the extensive fixation involves a demineralised spine.

Material and methods: From 1998 to 2001, seven patients aged 19 to 76 years (mean 58) were treated with an interbody cage and an autologous graft. Four patients with scoliosis had had prior posterior surgery (mean five operations, range 3 – 9 operations). All had exhibited non-union with repeated fistulisation at each prior anterior approach, in four cases with meti-R Staphylococcus associated once with a Streptococcus and twice with an Enterococcus. Three patients suffered severe radicular pain. Three of the post-trauma patients had undergone revision procedures to remove the posterior implants. All had developed nonunion with total loss of the initial correction in two cases, one with septic instability concerning the level above the fixation. Both infections were caused by meti-R Staphylococcus, associated with an Enterococcus in one case. Two persistent posterior fistulae had been reoperated earlier. The grafts involved one to four levels with no new posterior fixation except for one patient (two accesses to the thoracolumbar junction, five lumbosacral fusions, immobilisation for four to six months with a corset). Mean duration of postoperative antibiotics was four months (3–12 months). Fusion was confirmed by the radiological aspect of the grafts on the scan obtained at a mean 22 months follow-up (minimum follow-up 12 months).

Results: There were no cases of anterior infection except for one post-trauma patient where a posterior screw touched the disc (reactivation of infection without anterior abscess, posterior approach for revision and final fusion in kyphosis). There was no appreciable improvement in correction, but the six other patients fused with a clear clinical improvement (removal of rigid corset, reduction of antalgesics, mean time 6 months). Improvement was observed in the three patients with radicular pain. One patient who had undergone three prior anterior operations underwent the minimally invasive posterior revision with no particular intraoperative problem but later presented ureteral necrosis (secondary nephrectomy).

Discussion: This interbody grafting strategy is a possible solution to salvage mechanical failures subsequent to recurrent severe infection often due to multiple germs. The technique is more difficult in older patients with complex malformations. A positive disc sample is a factor of less satisfactory outcome. In the event of prior anterior revision, an ureteral catheter is advisable to limit the risk of necrosis. Use of intersomatic cages is not a problem and has allowed us to achieve primary and secondary stability in these patients with poor bone stock and this without supplementary infection problems.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 51 - 51
1 Jan 2004
Lazennec J Del Vecchio R Techentko MA Rafati N Saillant G
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Purpose: We analysed the radiographic course of anterior lumbar interbody fusion achieved via a minimal anterior extraperitoneal approach.

Material and methods: From January 1996 to December 2001, we operated 198 patients with this technique. Twenty-one patients were excluded from the analysis (two deaths, three tumours, 16 follow-ups less than 12 months). Mean age of the 177 patients retained for study was 53 years (range 22–78). Mean follow-up was 2.7 years. The 55 post-trauma cases involved essentially thoracolumbar junction. The 122 cases of degenerative lumbar spine included 14 cases of scoliosis, 26 cases of spondylolisthesis, 72 cases of unstable spines after primary posterior surgery, and 10 isolated degenerative discs. Only eight patients did not have posterior fixation. Fusion (globally 360 levels) concerned one disc in 89 patients, two discs in 71, three discs in 17. Cancellous autologous grafts were used with cages. Tricortical grafts were implanted after corporectomy (n=23). Radiological fusion was confirmed by the absence of a mobility chamber around the pedicular screws, the cages or the tricortical grafts, and by searching for loss of sagittal angles (digitalized scans and x-ray, Auto Cad L.T.2000).

Results: 1) Early postoperative status. For the post-trauma cases (65 fused levels, 55 patients), a simple callus was observed in 28. For the others, mean correction was 4° per level. 2) Angle loss. For the trauma cases, mean angle loss was 3.9° in 36 cases (29 grafts on a single level). There were two partial expulsions of the tricortical grafts implanted in osteoporotic patients; revision was not attempted. Mean angle loss for the 65 grafted levels was 2°. For the degenerative cases, mean angle loss was 3.7° for 172 fused levels (112 patients). Cage expulsion on a grade 3 spondylolisthesis did not warrant revision. Two cage impactions did not cause significant loss of angle. 3) Anatomic status of the grafts. Fusion was achieved at all levels without cage or tri-cortical graft rupture. We observed a partial but stable lucent line around the case in five cases.

Discussion: The rate of fusion reported after anterior lumbar interbody fusion has varied from 55 to 100% in the literature. This technique is an original approach for trauma victims avoiding the need for extensive posterior assemblies and/or the damage caused by a wide anterior approach. For the degenerative spine, the mediocre quality of the bone and the frequency of several level fusions is not a particular problem.

Conclusion: Anterior lumbar interbody fusion is an interesting method for reinforcing posterior fixation with a real efficacy in terms of effective fusion.