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Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 342 - 343
1 Sep 2005
Colwell C Patil S Ezzet K Kang S D’Lima D
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Introduction and Aims: A significant proportion of patients currently undergoing total knee arthroplasty have uni-compartmental disease. Unicondylar knee replacement (UKA) offers the benefits of less bone resection and better soft tissue retention. However, knee kinematic changes after UKA have not been established.

Method: A significant proportion of patients currently undergoing total knee arthroplasty have uni-compartmental disease. Unicondylar knee replacement (UKA) offers the benefits of less bone resection and better soft tissue retention. However, knee kinematic changes after UKA have not been established.

Results: In the normal knee, knee flexion was accompanied by femoral rollback and tibial internal rotation. Similar patterns of rollback and rotation were seen after UKA. Surprisingly, resecting the ACL did not affect rollback or tibial rotation. However, tibial rotation was significantly different and was more variable after TKA. This suggests that loss of the ACL may not be the major cause of abnormal kinematics after TKA.

Conclusion: Abnormal kinematics have been previously reported after TKA. However, UKA appeared to maintain normal kinematics. This study reported kinematic advantages to UKA, in addition to less bone resection and better recovery.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 340 - 340
1 Sep 2005
Colwell C D’Lima D Patil S Steklov N
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Introduction and Aims: Complications after total knee arthroplasty (TKA) have been attributed to soft-tissue imbalance. The current approach to soft-tissue balance is static measurements in extension and 90 degrees flexion. Dynamic balancing during the entire range of flexion may be more valuable.

Method: Complications after total knee arthroplasty (TKA) have been attributed to soft-tissue imbalance. The current approach to soft-tissue balance is static measurements in extension and 90 degrees flexion. Dynamic balancing during the entire range of flexion may be more valuable.

Results: All knees (in vitro and in vivo) initially recorded imbalance in the tibial forces: mean 18N (6–72) in the mediolateral and 26N (13–108) in the anteroposterior direction. After soft-tissue balancing, the mean imbalance reduced by 87%. Even when knees appeared well balanced at zero and 90-degree flexion, there was imbalance [mean 22N (2–34)] at flexion angles between zero and 90 degrees. The 2mm thicker insert increased forces by a mean of 89% (22–180%).

Conclusion: Soft-tissue balance in TKA remains a complex concept. The routine instruments used for soft-tissue balance only detect mediolateral imbalance. Even when accurate static balancing was achieved, dynamic measurements revealed imbalance in mid-flexion. These results explain some of the variability in knee kinematics after TKA and the incidence of mid-flexion instability.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 414 - 414
1 Apr 2004
D’Lima D Hermida J Bergula A Chen P Colwell C
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Polyethylene wear is a significant factor limiting survivorship of total knee arthroplasty (TKR). Crosslinking of polyethylene has been shown to significantly reduce wear in hip arthroplasty but has not been reported for TKR. This study measured wear in polyethylene cross-linked to two levels in a knee wear simulator.

Six polyethylene knee inserts were tested in a knee wear simulator. Inserts were manufactured from polyethylene crosslinked to two different levels: 2.5 Mrad (Low-X) and 10.5 Mrad (High-X). Each implant was enclosed in a closed lubricant (50% alpha fraction calf serum) recirculation chamber, maintained at 37°C and changed every 500,000 cycles. Physiologic levels of load and motion were applied at 1 Hz for a total of 6,000,000 cycles. Wear was measured by the gravimetric method before wear testing and at every 500,000 cycles. Semi-quantitative wear assessment was performed by imaging the insert surfaces at 10x magnification.

The Low-X inserts demonstrated significantly higher wear rates (mean 4.66 mg/million cycles) than the High-X inserts (mean 1.55 mg/million cycles, p < 0.001). Wear scars on the Low-X inserts were irregular and visibly deeper than those on the High-X inserts. The machining marks on the surface of the insert were also better preserved in the High-X insert wear scars. These results suggest that crosslinked PE can significantly reduce wear in TKR under physiologic conditions. This can result in reduced lysis and increased survivorship. Localized damage can cause catastrophic failure in polyethylene knee inserts. Therefore, further studies are necessary to evaluate wear under these conditions.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 5 - 5
1 Jan 2004
D’Lima D Chen P Colwell C
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Polyethylene contact stresses have been shown to correlate with wear in total hip arthroplasty (THA). Several liner designs have been introduced in an attempt to increase stability or reduce impingement and increase range of motion. This study analyzed the effect of liner design on range of motion (ROM) and PE contact stresses in a finite element model (FEM).

FEMs of four liner designs were generated: Generic was modelled as a simple hemisphere, Chamfer had a wide chamfer on the inner edge of the liner to increase ROM, Highwall had an extended lip to increase stability, and Anteverted created a 20° anteversion with lat-eralisation of the centre of rotation. With the liners in varying positions of abduction and anteversion, physiologic loads were applied through the femoral head. Hip ROM was measured by rotating the head and neck in different directions until prosthetic impingement.

Significant differences in ROM were seen relative to the Generic liner. Chamfer increased ROM by mean 16%. Highwall reduced ROM by mean 12%. Anteverted increased flexion by 17% but decreased extension, abduction, and external rotation. Contact stresses were also significantly affected by liner design and acetabular orientation. Overall for the same acetabular position, contact stresses were higher for Chamfer and lower for Highwall and Anteverted.

These results underline the complex interaction between cup design, hip stability, range of motion and contact stresses. Design features that increase stability tend to reduce contact stresses and ROM, while those features that increase ROM, tend to increase contact stresses. This data can help the surgeon match liner design to specific patient requirements.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 5 - 5
1 Jan 2004
Hermida J Patil S Chen P Colwell C D’Lima D
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This study measured polyethylene wear and correlated it with design features such as tibiofemoral conformity and contact areas.

Two femoral component designs were tested in a knee wear simulator. The femoral condyles of design A were flat-on-flat in the coronal plane, while those of design B were curved-on-curved. These femoral components were tested with two inserts. Insert PLI had a posterior lip, while insert C had a more curved sagital geometry, to improve stability in the anteroposterior direction. All components were tested for up to five million cycles in bovine serum lubricant. Triaxial forces were monitored to ensure that loading conditions were similar in all combinations tested. Gravimetric wear measurements were made at 500 000 cycle intervals. Contact stresses were measured using pressure sensitive film and dynamic finite element analysis.

Contact stresses were 22% higher for inserts tested with design A compared to design B. Sliding distance, sliding velocity, and patterns of crossing motion were found to be comparable between the two femoral designs. Inserts tested with design A wore significantly more (mean 10.9 mg/million cycles) than design B (mean 5.71 mg/million cycles, p < 0.001). No appreciable differences were found between wear rates of insert PLI and insert C.

Component design can have a significant impact on polyethylene wear rate. Careful control of kinematic and loading conditions allowed for comparison between specific design features. Increase in tibio-femoral contact area led to reduction of contact stresses, which was reflected in the reduced wear rate.