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The Bone & Joint Journal
Vol. 97-B, Issue 3 | Pages 312 - 317
1 Mar 2015
Amanatullah DF Howard JL Siman H Trousdale RT Mabry TM Berry DJ

Revision total hip arthroplasty (THA) is challenging when there is severe loss of bone in the proximal femur. The purpose of this study was to evaluate the clinical and radiographic outcomes of revision THA in patients with severe proximal femoral bone loss treated with a fluted, tapered, modular femoral component. Between January 1998 and December 2004, 92 revision THAs were performed in 92 patients using a single fluted, tapered, modular femoral stem design. Pre-operative diagnoses included aseptic loosening, infection and peri-prosthetic fracture. Bone loss was categorised pre-operatively as Paprosky types III-IV, or Vancouver B3 in patients with a peri-prosthetic fracture. The mean clinical follow-up was 6.4 years (2 to 12). A total of 47 patients had peri-operative complications, 27 of whom required further surgery. However, most of these further operations involved retention of a well-fixed femoral stem, and 88/92 femoral components (97%) remained in situ. Of the four components requiring revision, three were revised for infection and were well fixed at the time of revision; only one (1%) was revised for aseptic loosening. The most common complications were post-operative instability (17 hips, 19%) and intra-operative femoral fracture during insertion of the stem (11 hips, 12%). Diaphyseal stress shielding was noted in 20 hips (22%). There were no fractures of the femoral component. At the final follow-up 78% of patients had minimal or no pain.

Revision THA in patients with extensive proximal femoral bone loss using the Link MP fluted, tapered, modular stem led to a high rate of osseointegration of the stem at mid-term follow-up.

Cite this article: Bone Joint J 2015; 97-B:312–17.


The Bone & Joint Journal
Vol. 95-B, Issue 11_Supple_A | Pages 11 - 16
1 Nov 2013
Sierra RJ Mabry TM Sems SA Berry DJ

Total hip replacement (THR) after acetabular fracture presents unique challenges to the orthopaedic surgeon. The majority of patients can be treated with a standard THR, resulting in a very reasonable outcome. Technical challenges however include infection, residual pelvic deformity, acetabular bone loss with ununited fractures, osteonecrosis of bone fragments, retained metalwork, heterotopic ossification, dealing with the sciatic nerve, and the difficulties of obtaining long-term acetabular component fixation. Indications for an acute THR include young patients with both femoral head and acetabular involvement with severe comminution that cannot be reconstructed, and the elderly, with severe bony comminution. The outcomes of THR for established post-traumatic arthritis include excellent pain relief and functional improvements. The use of modern implants and alternative bearing surfaces should improve outcomes further.

Cite this article: Bone Joint J 2013;95-B, Supple A:11–16.


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 11_Supple_A | Pages 157 - 166
1 Nov 2012
Rosenberg AG Berend ME Berry DJ Della Valle CJ MacDonald SJ Minas T

This conversation represents an attempt by several arthroplasty surgeons to critique several abstracts presented over the last year as well as to use them as a jumping off point for trying to figure out where they fit in into our current understanding of multiple issues in modern hip and knee arthroplasty.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 430 - 430
1 Nov 2011
Berry DJ
Full Access

Metal-on-metal bearings have become popular in the last ten years because of a low wear rate combined with the ability to use large head sizes for conventional total hip arthroplasty (THA) and to facilitate resurfacing hip arthroplasty. Further advantages of metal-metal bearings include the fact that they are not at risk for fracture, and they can be made as modular or non-modular acetabular implants.

It was recognized early that metal-on-metal implants had the potential to increase serum ion levels, and this was demonstrated in a number of studies. The significance of elevated ion levels, however, for most patients has been primarily a theoretical concern of toxicity, carcinogenesis or mutagenicity, and to date very few, if any, systemic problems related to systemic metal ions have been documented with certainty. Nevertheless, most surgeons have avoided use of the implants in patients who are likely to become pregnant, patients with renal disease, or patients with major systemic illnesses which have a high likelihood of leading to renal disease. Furthermore, most have avoided using them in patients with known dermal metal allergies, even though the connection between dermal metal allergies and metal bearings has not been established.

Unexpectedly, an extremely important concern has emerged with metal bearings: the finding of local inflammatory reactions related to metal bearings. These inflammatory reactions can take several forms including pain with a milky effusion, local tissue necrosis, or large fluid collections or pseudotumors. The histology of these different reactions appears to be predominantly lymphocytic in nature and a term for at least some of these reactions has been coined “AVALS”. Whether these local reactions are primarily immunologic in nature or primarily related to dose of local metal ions or debris remains uncertain. While there is much still to be learned, it appears that certain patient populations may be at increased risk for metal reactions, possibly related to implant size (women and smaller patients). It also seems verticallyoriented implants, which create edge loading, increase wear and increase risk of local metal reactions.

Perhaps the most important question is the incidence of local metal reactions, which remains to be defined. To date the problems in most series have been infrequent, less than 1 or 2 percent. However, in a few selected series the incidence has been higher, and when screening has been done for asymptomatic patients with fluid or masses around the joint, the rate has been higher in at least one reported series.

Surgeons may interpret the importance of local metal reactions differently, but certainly ultimately incidence of this problem will have a very major effect on the future of these bearings.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 461 - 462
1 Nov 2011
Berry DJ
Full Access

It has become a platitude that total knee arthroplasty (TKA) is an excellent operation, provides good pain relief, and over 90% survivorship at 20 years in many series. While all these points are true, total knee arthroplasty as practiced currently still will not meet the demands of many patients who will desire the procedure in the next ten years. The reasons for this include changing demographics of TKA and the changing demands of TKA candidates. TKA is being performed more frequently in patients under 60, in fact this is the fastest growing group of patients by percent growth. We performed a population-based study of trends utilization of TKA and found increasing TKA utilization in all age groups over time but the greatest increase by percent in the youngest patients. Furthermore, younger patients now no longer tend to be lowactivity patients with inflammatory disease. The percentage of patients with primary osteoarthritis and post traumatic arthritis has increased dramatically. Long-term studies of TKA have shown such durability in part because many of the younger patients were Charnley Class C patients, and because historically most TKA patients were older with an average age of most early series of around 69 years. This means there were far fewer young patients in early TKA series than in early THA series. This is important because material failures occur predominantly in younger patients and durability is a greater concern in younger patients, so one may predict that this younger, more active group will not enjoy the same level of TKA durability reported in the literature unless technology improves.

Total knee arthroplasty patients are more active than one might predict. In a study of 1200 patients surveyed at five years the average UCLA score was 7 out of 10. Younger patients achieved a higher activity level but were in general less satisfied with activity provided by TKA than older patients. This implies there is a need for better designs and surgery to facilitate more normal kinematics, more flexion, and more quadriceps strength. A study by Weiss and Noble (CORR 2002) identified specific activities associated with limitations after knee arthroplasty.

Furthermore, a study by Bourne and associates demonstrated lower satisfaction scores after total knee arthroplasty than hip arthroplasty. Finally, in our study of activity levels after knee arthroplasty we found that 16% of current patients participate in heavy labor or sports not recommended by Knee Society guidelines. These patients tend to be younger and predominantly male. This implies there is a subset of the population already doing things that will challenge the current generation of total knee arthroplasty and more patients want to do these activities and already do so. Therefore, there is a need for improved implant durability and improved knee function after knee arthroplasty. This suggests the methods of fixation may need to evolve to accommodate higher demands, and bearing surfaces definitely need to evolve to accommodate higher demands. Finally, more sophisticated implant kinematics to avoid or compensate for anterior cruciate ligament and posterior collateral ligament deficiency and more sophisticated surgery to optimize implant alignment and soft tissue balancing in the individual patient will be necessary to achieve more normal patient knee kinematic stability, strength and “feel”. Finally, we will need better and more sensitive scoring systems to detect improvements in future TKA surgery and design in the future.