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Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 234 - 234
1 Mar 2004
Morris M Williams J Thake A Brown J Yang L
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Aims: To investigate the optimal dimension interference screw for fixation of a tendon graft in a bone tunnel. Methods: A porcine model was developed to represent ACL reconstruction in the distal femur. A standard 8mm size pig flexor tendon graft was inserted into a standard 8mm bone tunnel. The screw dimensions were varied. The tendon was loaded with a constant force using a Universal Testing Machine. The construct was tested to failure at a rate of 50mm/minute. Load, deformation data and mechanism of construct failure were recorded. The screw diameters of 7, 8 and 9mm and lengths of 20, 25 and 30mm were tested in 80 individual reconstructions. Results: The mean pull out force was similar between the 7mm (191N) and 8mm screws (188N), but significantly different for the 9mm screw (109N) (p< 0.05) The 30mm screw (231N) was marginally better than the 20mm screw (215N) (p> 0.05). The mechanism of failure however, was significantly different between the groups. All grafts fixed with a 9mm screw failed at the tunnel opening (100%), whereas those fixed with a 7mm screw failed by slippage of the graft along the length of the tunnel (83%). The screw length did not affect the mechanism of graft failure. Conclusion: Our results suggest that a screw size equal to or 1mm less than the diameter of the tunnel gives the optimum initial interference screw fixation of tendon in a bone tunnel.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 306 - 306
1 Mar 2004
Ali AM Saleh M Bolongaro S Yang L
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Objective: To compare the mechanical stability of þxation of bicondylar tibial fractures using available internal and external þxation techniques. Method: A bicondylar tibial fracture was simulated on a uniform synthetic bone and tested with loading to failure. Following power calculations, seven tibias were used for each þxation method;þve types of þxation were tested: 1)Dual plating. 2)Ring Fixator with interfragmentary screws. 3)Hybrid þxator (Ring-Bar) with interfragmentary screws. 4)Lat-eral plate and medial monolateral external þxator. 5)Lateral plate and medial interfragmentary screws. The specimens were tested in compression to failure. The vertical subsidence in either medial or lateral plateau was measured using an electrical transducer. Results: In all cases the mode of failure was consistent with collapse occurring in the medial plateau. There was no signiþcant difference in the ultimate strength between dual plating and the ring þxator [4218N, 4184N respectively; P=0.28, t test]. Failure was seen at lower loads with the other þxation systems

Conclusion: The Ring Fixator and dual plating demonstrated a greater strength and the most stable þxation, choice may depend on tissue viability and surgeon preference. Furthermore mobilisation of the patient may be undertaken earlier with more conþdence using these two methods rather than less stable techniques.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 306 - 307
1 Mar 2004
Ali AM Yang L Eastell R Saleh M
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Objective: To assess the inßuence of bone density on the þxation strength of bicondylar tibial plateau fractures. Method: Sixteen cadaver tibias were randomised into two groups to receive either dual plating or ring external þxation to stabilise a bicondylar tibial plateau fracture created with a standard method. The randomisation was stratiþed by BMD measured by DXA (above and below the mean). Cyclic axial compression tests were performed with increasing peak loads. Inter-fragmentary shear displacements were measured using four extensometers. Failure was deþned as over 3mm displacement. Results: There was a strong correlation between failure load and BMD [r=0.81, P< 0.001]. The mean failure load of the low BMD group (2701 N) was signiþcantly less than that with the high BMD (4530 N) [t-test=0.003]. The failure loads of the two þxation groups were not signiþcantly different (3520 N for the dual plating and 3710 N for the external þxation) [t-test=0.78]. BMD had a signiþcant effect on the failure load in the dual plating group [t-test=0.03], but not in the external þxation group [t-test=0.1]. Discussion: Failure of þxation has been reported as a common complication of bicondylar tibial plateau fractures with a rate as high as 30%. Osteoporosis and poor bone quality are considered important contributory factors. In our study this inßuence was evident with plating, but not with ring þxation. Ring þxation may be the preferred method of þxation for tibial plateau fractures in the elderly and osteoporotic patients.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 12 - 13
1 Jan 2003
Metcalfe A Yang L Saleh M
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Experience has shown that oblique fractures can be slow to heal and this has been attributed to excess shear at the fracture site. We routinely treat fractures with hybrid external fixation. In previous studies, olive wires placed through the fracture site reduced shear and this has improved healing times. When the fracture is oblique in the sagittal plane, anatomical constraints prevent the use of olive wires and a new solution is required.

A sawbone tibia with a distal sagittal plane oblique fracture (70° obliquity) was stabilised with a Sheffield Hybrid Fixator. In a pilot study various methods of fixation were tested and six were chosen for further testing. Since the pull-out strength of threads in the plastic bone was poor, olive wires cut behind the olive were used as a mechanically equivalent model for the push-pull system. Seventy degree steerage pins could not be used so 25° pins were tested instead. Cyclic compressive forces (at 10mm/min) of up to 200N axially and in four off-axis positions were applied using a universal testing machine. Fracture site linear motion in three dimensions was measured using an inter-fragmentary motion device, sampled at 100Hz. A standard frame was tested before and after each adaptation and all six methods were applied sequentially to each model.

The results suggest that: I) Arched wires are effective especially under greater bends, 2) Push-pull wires are effective and provide a minimally disruptive solution, 3) Steerage pins are effective especially at steeper obliquities but this may not always be practical, and 4) Placing a half pin in the distal fragment is beneficial but less effective than the use of 2 transverse half pins acting in a compression system (Hutson technique).


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 12 - 12
1 Jan 2003
Cai G Coulton L Yang L Saleh M
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Previous studies in animal models of limb lengthening have shown a wide spectrum of histopathological changes during distraction phase. Much less is known about the structural response of muscle during the consolidation phase. This study aimed to observe and score changes in morphology, weight, length and maximal perimeter of gastrocnemius during the distraction and consolidation phases.

Thirty two immature New Zealand white rabbits were divided into two equal groups: lengthening and sham. In each group, half of the rabbits were killed at the end of lengthening and half 5 weeks later. A bilateral external fixator was applied to tibia and a mid-diaphysis osteotomy performed. The lengthening rate was 0.4 mm twice daily with an initial delay of 7 days. 30% lengthening was achieved in 4 to 5 weeks. After sacrifice, the whole gastrocnemius was taken from its attachments. Its weight, length and maximal perimeter were measured. At the middle of belly, a specimen 0.5cm in length was taken from the medial gastrocnemius for H& E and Masson trichrome staining. A scoring system was used to achieve a semi-quantitative analysis of the histopathological changes in gastrocnemius.

No abnormal changes were observed in the sham side. Degeneration, atrophy and endomysial fibrosis were all found in the lengthened side. The scores of histopathological changes between the end of lengthening and 5 weeks later showed a decreasing trend, but no significant difference. The weight and perimeter decreased and length increased in the lengthening side. The weight, perimeter and length of gastrocnemius in both lengthening and control sides increased at 5 weeks after the end of lengthening.

Muscular atrophy, as shown by a decrease in weight, perimeter and muscle fibre size, occurred and might be due to the combined effect of continuous muscle stretching and inactivity. Continuous stretching of muscles beyond a certain point produced damage. Some studies reported that damage to muscle fibres, which has been shown as degeneration and fibrosis in this study, can release and activate satellite cells. As myoblast precursors, satellite cells become myoblasts, which proliferate and fuse into the microlesioned areas, regenerating and repairing myofibrils. Also, the immature muscles have more active abilities of proliferation, regeneration, growth and healing. In this study gastrocnemius growth shown by an increase in weight, perimeter and length occurred during the consolidation phase of 5 weeks. The mean scores of histopathological changes in gastrocnemius decreased during consolidation period, indicating some recovery of damage to muscle. It is not clear whether this reflects a normal response, which would have been seen in other studies had samples been taken later or whether it is a unique response of the immature animal.


The Journal of Bone & Joint Surgery British Volume
Vol. 84-B, Issue 1 | Pages 137 - 140
1 Jan 2002
Piska M Yang L Reed M Saleh M

An innovative Kirschner (K-) wire point was developed and compared in fresh pig femora in terms of drilling efficiency and temperature elevation with the trochar and diamond points currently used in clinical practice. The tips of thermal couples were machined to the defined geometry and the temperature measured during drilling. Using the same drill speed (rev/min) and feed rate, the new K-wire point produced the lowest thrust force and torque as measured by a Kistler dynamometer. Drill point temperatures were highest with the trochar geometry (129 ± 6°C), followed by the diamond (98 ± 7°C). The lowest temperatures were recorded with the Medin K-wire (66 ± 2°C). On repeated drilling it could be used for up to 30 holes before reaching the less satisfactory drill performance of the diamond tip. The new K-wire provides a better alternative as it requires less effort for insertion, generates less heat and may be re-used.