Abstract. Objective. Meta-analysis of clinical trials highlights that non-operative management of degenerative knee meniscal tears is as effective as surgical management. Surgical guidelines though support arthroscopic partial meniscectomy which remains common in NHS practice. Physiotherapists are playing an increasing role in triage of such patients though it is unclear how this influences clinical management and patient outcomes. Methods. A 1-year cohort (July 2019–June 2020) of patients presenting with MRI confirmed degenerative meniscal tears to a regional orthopaedic referral centre (3× ESP physiotherapists) was identified. Initial clinical management was obtained from medical records alongside subsequent secondary care management and routinely collected outcome scores in the following 2-years. Management options included referral for surgery, conservative (steroid injection and rehabilitation), and no active treatment. Outcome scores collected at 1- and 2-years included the Forgotten Joint Score-12 (FJS-12) questionnaire and 0–10 numerical rating scales for worst and average pain. Treatment allocation is presented as absolute and proportional figures. Change in outcomes across the cohort was evaluated with repeated measures ANOVA, with Bonferroni correction for multiple testing, and post-hoc Tukey pair-wise comparisons. As treatment decision is discrete, no direct contrast is made between outcomes of differing interventions but additional explorative outcome change over time evaluated by group. Significance was accepted at p=0.05 and effect size as per Cohen's values. Results. 81 patients, 50 (61.7%) male, mean age 46.5 years (SD13.13) presented in the study timeframe. 32 (40.3%) received conservative management and 49 (59.7%) were listed for surgery. Six (18.8%) of the 32 underwent subsequent surgery and nine of the 49 (18.4%) patients switched from planned surgery to receiving non-operative care. Two post-operative complications were noted, one cerebrovascular accident and one deep vein thrombosis. The cohort improved over the course of 2-years in all outcome measures with improved mean FJS-12 (34.36 points), mean worst pain (3.74 points) average pain (2.42 points) scores. Overall change (all patients) was statistically significant for all outcomes (p<0.001), with sequential year-on-year change also significant (p<0.001). Effect size of these changes were large with all Cohen-d values over 1. Controlling for age and BMI, males reported superior change in FJS-12 (p=0.04) but worse pain outcomes (p<0.03). Further explorative analysis highlighted positive outcomes across all surgical, conservative and no active treatment groups (p<0.05). The 15 (18%) patients that switched between surgical and non-surgical management also reported positive outcome scores (p<0.05). Conclusion(s). In a regional specialist physiotherapy-led soft tissue knee clinic around 60% of degenerative meniscal tears assessed were referred for surgery. Over 2-years, surgical, non-operative and no treatment management approaches in this cohort all resulted in clinical improvement suggesting that no single strategy is effective in directly treating the meniscal pathology, and that perhaps none do. Clinical intervention rather is directed at individual symptom management based on clinical preferences. Declaration of Interest. (b) declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported:I declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project

Introduction. Transtibial osseointegration (TFOI) for amputees has limited but clear literature identifying superior quality of life and mobility versus a socketed prosthesis. Some amputees have knee arthritis that would be relieved by a total knee replacement (TKR). No other group has reported performing a TKR in association with TTOI (TKR+TTOI). We report the outcomes of nine patients who had TKR+TTOI, followed for an average 6.5 years. Materials & Methods. Our osseointegration registry was retrospectively reviewed to identify all patients who had TTOI and who also had TKR, performed at least two years prior. Four patients had TKR first the TTOI, four patients had simultaneous TKR+TTOI, and one patient had 1 OI first then TKR. All constructs were in continuity from hinged TKR to the prosthetic limb. Outcomes were: complications prompting surgical intervention, and changes in daily prosthesis wear hours, Questionnaire for Persons with a Transfemoral Amputation (QTFA), and Short Form 36 (SF36). All patients had clinical follow-up, but two patients did not have complete survey and mobility tests at both time periods. Results. Six (67%) were male, average age 51.2±14.7 years. All primary amputations were performed to manage traumatic injury or its sequelae. No patients died. Five patients (56%) developed infection leading to eventual transfemoral amputation 36.0±15.3 months later, and 1 patient had a single debridement six years after TTOI with no additional surgery in the subsequent two years. All patients who had transfemoral amputation elected for and received transfemoral osseointegration, and no infections occurred, although one patient sustained a periprosthetic fracture which was managed with internal fixation and implant retention and walks independently. The proportion of patients who wore their prosthesis at least 8 hours daily was 5/9=56%, versus 7/9=78% (p=.620). Even after proximal level amputation, the QTFA scores improved versus prior to TKR+TTOI, although not significantly: Global (45.2±20.3 vs 66.7±27.6, p=.179), Problem (39.8±19.8 vs 21.5±16.8, p=.205), Mobility (54.8±28.1 vs 67.7±25.0, p=.356). SF36 changes were also non-significant: Mental (58.6±7.0 vs 46.1±11.0, p=.068), Physical (34.3±6.1 vs 35.2±13.7, p=.904). Conclusions. TKR+TTOI presents a high risk for eventual infection prompting subsequent transfemoral amputation. Although none of these patients died, in general, TKR infection can lead to patient mortality. Given the exceptional benefit to preserving the knee joint to preserve amputee mobility and quality of life, it would be devastating to flatly force transtibial amputees with severe degenerative knee joint pain and unable to use a socket prosthesis to choose between TTOI but a painful knee, or preemptive transfemoral amputation for transfemoral osseointegration. Therefore, TTOI for patients who also request TKR must be considered cautiously. Given that this frequency of infection does not occur in patients who have total hip replacement in association with transfemoral osseointegration, the underlying issue may not be that linked joint replacement with osseointegrated limb replacement is incompatible, but may require further consideration of biological barriers to ascending infection and/or significant changes to implant design, surgical technique, or other yet-uncertain factors

Aims

The purpose of this study was to compare the clinical outcomes, mortalities, implant survival rates, and complications of total knee arthroplasty (TKA) in patients with or without hepatitis B virus (HBV) infection over at least ten years of follow-up.

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The aim of this study was to determine the long-term mortality rate, and to identify factors associated with this, following primary and revision knee arthroplasty (KA).

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The aetiologies of common degenerative spine, hip, and knee pathologies are still not completely understood. Mechanical theories have suggested that those diseases are related to sagittal pelvic morphology and spinopelvic-femoral dynamics. The link between the most widely used parameter for sagittal pelvic morphology, pelvic incidence (PI), and the onset of degenerative lumbar, hip, and knee pathologies has not been studied in a large-scale setting.

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The aim of this study was to determine the long-term risk of undergoing knee arthroplasty in a cohort of patients with meniscal tears who had undergone arthroscopic partial meniscectomy (APM).

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The aim of this study was to determine and compare the congruency of the articular surface contact area of the patellofemoral joint (PFJ) during both active and passive movement of the knee with the use of an MRI mapping technique in both the stable and unstable PFJ.

Not all degenerative knees need a total knee replacement. Over the last few decades we have shifted our surgical treatment of end-stage osteoarthritis (OA) of the knee to a “compartmental approach” resulting in approximately half of end-stage OA knees receiving a partial knee replacement. Of these an emerging procedure is isolated lateral compartment replacement with the indications being isolated bone-on-bone osteoarthritis or avascular necrosis of the lateral compartment of the knee. Associated significant patellofemoral disease and inflammatory arthritis are contraindications. The purpose of this study is to present the indications, surgical technique, and early outcome of lateral partial knees from our institution. From Aug 2011 until June 2017 we have performed 3,548 knee arthroplasties. Of these 147 were fixed bearing lateral partial knee replacements via a lateral parapatellar approach (4%), 1,481 medial partial knee replacements (42%), and 1,920 total knee replacements (54%). The average age was 66 years old and 76% were female. Average follow-up in the lateral partials was 1.3 years (range 0.5 years to 6 years). Knee Society Scores improved from 41 (pre-op) to 86 points (post-op). Range of motion improved from 6 – 113 degrees (pre-op) to 0 – 123 degrees (post-op). No knees were revised to a TKA. One knee required I&D for traumatic wound dehiscence. This is the largest single center series of lateral partial knee replacements. We have observed this cohort to have more female patients and gain additional range of motion compared to our historic cohorts of TKA's. Longer-term follow-up is needed for determination of implant and unreplaced compartment survivorship. We believe the lateral partial knee replacement to be a viable option for isolated lateral compartment disease in approximately 4% of patients

Aims

Patients with osteoarthritis of the knee commonly have degenerative meniscal tears. Arthroscopic meniscectomy is frequently performed, although the benefits are debatable. Recent studies have concluded that there is no role for arthroscopic washout in osteoarthritis of the knee. Our aim was to perform a systematic review to assess the evidence for the efficacy of arthroscopic meniscectomy in patients with meniscal tears and degenerative changes in the knee.

Background. Total knee arthroplasty (TKA) is a cost-effective surgical procedure for degenerative knee disease and has good long-term results. However, these results are not always related to patient satisfaction and functional outcome. With an increasing demand of surgeons and patients on functioning of total knee implants, the need for adequate objective outcome measures is high. Imaging of the knee is commonly used in clinical practice and research to objectively measure many different outcome parameters concerning the implant, such as alignment and complications.1 However, techniques on comparison of the sagittal contour of the knee before and after implant placement are scarce. Goal. To develop and describe a standardized method for measuring the sagittal contour of the implant in a 3D model of the knee before and after implant placement. Methods. Images of the static knee of a subject are obtained in-vivo using fluoroscopy over a 180° sweep at 15 frames per second (MultiDiagnost Eleva, Philips, The Netherlands). A 3D model of the knee is constructed in accompanying software (3D-RX, Philips, The Netherlands) and is subsequently imported in OsiriX imaging software (Pixmeo, Switzerland). In Osirix, a reproducible coordinate system is obtained using the bone stub axis and the anatomical epicondylar axis as references [Fig. 1]. We quantified the sagittal contour of the distal femur in two parameters: the flexion angle of femoral component and the sagittal profile of the implant. To measure the flexion angle, the image is located in the midtrochlear plane. The angle is measured between the bone stub axis and the neutral line of the femoral component [Fig. 2]. To measure the sagittal profile of the distal femur, the lengths of three lines connecting the anatomical epicondylar axis of the distal femur and the outer border of the femur/prosthesis are summed. This is done both anterior and posterior [Fig. 3]. These profiles are measured in planes of the lateral and medial condyle and of the midtrochlear plane. Due to the reproducible coordinate system, the profiles can be compared for the knee before and after implant placement. Conclusion. Using fluoroscopy and readily available 3D imaging software we have developed a technique for measuring valuable parameters concerning implant placement in TKA. This technique can be used for scientific purposes concerning comparison of the knee before and after implant placement and to study its effect on functional and biomechanical outcome after TKA

The purpose of this study was to compare clinical outcomes of total knee arthroplasty (TKA) after manipulation under anaesthesia (MUA) for post-operative stiffness with a matched cohort of TKA patients who did not requre MUA.

In total 72 patients (mean age 59.8 years, 42 to 83) who underwent MUA following TKA were identified from our prospective database and compared with a matched cohort of patients who had undergone TKA without subsequent MUA. Patients were evaluated for range of movement (ROM) and clinical outcome scores (Western Ontario and McMaster Universities Arthritis Index, Short-Form Health Survey, and Knee Society Clinical Rating System) at a mean follow-up of 36.4 months (12 to 120). MUA took place at a mean of nine weeks (5 to 18) after TKA. In patients who required MUA, mean flexion deformity improved from 10° (0° to 25°) to 4.4° (0° to 15°) (p < 0.001), and mean range of flexion improved from 79.8° (65° to 95°) to 116° (80° to 130°) (p < 0.001). There were no statistically significant differences in ROM or functional outcome scores at three months, one year, or two years between those who required MUA and those who did not. There were no complications associated with manipulation.

At most recent follow-up, patients requiring MUA achieved equivalent ROM and clinical outcome scores when compared with a matched control group. While other studies have focused on ROM after manipulation, the current study adds to current literature by supplementing this with functional outcome scores.

Cite this article: Bone Joint J 2015;97-B:1640–4.

Patients with skeletal dysplasia are prone to developing advanced degenerative knee disease requiring total knee replacement (TKR) at a younger age than the general population. TKR in this unique group of patients is a technically demanding procedure due to the bone deformity, flexion contracture, generalised hypotonia and ligamentous laxity. We set out to retrospectively review the outcome of 11 TKR's performed in eight patients with skeletal dysplasia at our institution using the SMILES custom-made rotating-hinge total knee system. There were 3 males and 5 females with mean age 57 years (range, 41–79 years), mean height 138 cm (range, 122–155 cm) and mean weight 56 kg (range, 40–102 kg). Preoperative diagnoses included achondroplasia, spondyloepiphyseal dysplasia, pseudoachondroplasia, multiple epiphyseal dysplasia, morquio syndrome, diastrophic dysplasia and Larson's Syndrome. Patients were followed clinically and radiographically for a mean of 7 years (range, 3–11.5 years). Knee pain and function improved in all 11 joints. Mean Knee Society clinical and function scores improved from 24 (range, 14–36) and 20 points (range, 5–40) preoperatively to 68 (range, 28–80) and 50 points (range, 22–74) respectively at final follow-up. Four complications were recorded (36%), including a patellar fracture following a fall, a tibial periprosthetic fracture, persistent anterior knee pain and a femoral component revision for aseptic loosening. Our results suggest that custom rotating-hinge TKR in patients with skeletal dysplasia is effective at relieving pain, optimising movement and improving function. It compensates for bony deformity and ligament deficiency and reduces the need for corrective osteotomy. Patellofemoral joint complications are frequent and functional outcome is worse than primary TKR in the general population. Submission endorsed by Mr Peter Calder, Consultant Orthopaedic Surgeon and Society member

Purpose of the study: Total knee arthroplasty (TKA) is considered to be an effective treatment for degenerative knee joint disease when the functional impairment and the pain fail to respond to medical treatment. The success of TKA is determined by the degree of pain relief, functional recovery, and implant survival. For many years, those advocating or not preservation of the posterior cruciate ligament (PCL) have animated lively debates. Although a consensus has not been reached, posterior stabilised prostheses and prostheses with a mobile plateau are commonly implanted. The purpose of our study was to compare the outcomes obtained with fixed plateau TKA with preservation of the PCL with those obtained with other prostheses with or without sacrifice of the PCL with a fixed or mobile plateau. Material and methods: This was a prospective study in a single centre including a homogenous consecutive series of 12 TKA (cemented EUROP) with a fixed plateau and preservation of the PCL implanted from 1994 to 1996 in 117 patients aged 73 years on average. The International Knee Society scores were used for the clinical and radiographic assessment at ten years. Results: At ten years follow-up, 23 patients had died, 14 were lost to follow-up and 80 (82 knees) were evaluated clinically and 43 (45 knees) radiographically. The IKS knee score varied from 31 points (0–60) preoperatively to 88 points (30–98) postoperatively at last follow-up. The IKS function score was 40 points (0–90) preoperatively and 80 (25–100) at last follow-up. Lucent lines were noted for 59% of the condyles and 60% of the tibial plateaus. The lucencies were mainly located in the anterior and posterior zones of the femur (zones 1 and 4) and medially on the tibia (zones 1 and2). Two prostheses were revised at 8 and 11 years for loosening. The overall survival was 98.8% at ten years using the Kaplan-Meier method. Discussion: The clinical and radiological outcomes of prostheses with fixed plateaus and preserving the PCL in our series with one revision at 10 years were very satisfactory. Our results are comparable with earlier reports in the literature with or without sacrifice of the PCL with a fixed or mobile plateau. Conclusion: Longer term follow-up will be needed to confirm these results beyond ten years