The older literature (1960–1982) partially supports this assumption and iodine contrast agents have been modernized considerately. Is the effect the modern contrast agents have on the micro-organisms the cause of the fault negative culture results?
Staphylococcus aureus Staphylococcus epidermidis Enterococcus faecalis Streptococcus pyogenes Bacillus cereus Escherichia coli (E. coli) Pseudomonas aeruginosa Candida albicans Corynebacterium jeikeium Propionibacterium acnes Three different techniques were used: a disk diffusion test (classical resistance determination) and time-killing curves tests with a high inoculum (1,5*108 cfe/ml) and a low inoculum (10*3 cfe/ml) at 0, 2 and 24 hours.
The high and low inoculum tests: only the combinations Telebrix with both P. aeruginosa and E. coli showed any growth inhibition but a non-significant (p = 0.07) growth inhibition of log-1. This however, did not impede the detection of these bacteria. And with all other combinations there was no significant inhibition compared to the saline control and in every combination the percentage surviving number of bacteria was always higher than 30%.