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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_2 | Pages 30 - 30
1 Jan 2017
Kuenzler M Akeda M Ihn H McGarry M Zumstein M Lee T
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Posterolateral rotatory instability (PLRI) is the most common type of elbow instability. It is caused by an insufficiency of the lateral ligamentous complex, which consists mainly of the radial collateral ligament (RCL) and the lateral ulnar collateral ligament (LUCL).

Investigate the influence of serial sectioning of the lateral ligamentous complex on elbow stability in a cadaveric model of PLRI.

Kinematics of six fresh frozen cadaveric elbow specimens were measured by digitizing anatomical marks with a Microscribe 3DLX digitizing system (Revware Inc, Raleigh, NC). Each specimen was tested under four conditions: Intact, LUCL tear, LUCL and RCL tear, and complete Tear (LUCL, RCL and capsule tear). Each specimen was tested in 30°, 60° and 90° elbow flexion angles. Varus- laxity was measured in supination, pronation, and neutral forearm rotation positions and total forearm rotation was measured with 0.3 Nm of torque. Statistical significant differences between the conditions were detected using a two-way ANOVA with Tukey's post-hoc test.

The radial head dislocated in all specimens in LUCL and RCL tear and Comp but not in LUCL tear. Total forearm ROM did not increase form intact to LUCL tear (p>0.05) but significantly increased in LUCL and RCL tear (p=0.0002) and complete tear (p<0.0001) in all flexion angles. Additionally, ROM in LUCL tear significantly differed from LUCL and RCL tear and complete tear (p=0.0027 and p=0.0002). A similar trend was seen with the varus angle. While there was a significant difference when the intact condition was compared to both the LUCLand RCL tear and complete tear conditions (p<0.0001 and p<0.0001), there was no difference between the intact and LUCL tear conditions.

LUCL tear alone is not sufficient to cause instability and increase ROM and varus angle, meanwhile the increase of ROM and varus angle with additional capsular tear was not significant compared to LUCL and RCL tear. The increase of ROM after LUCL and RCL tear is an unknown symptom of PLRI.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_1 | Pages 25 - 25
1 Jan 2017
Kuenzler M Nuss K Karol A Schaer M Hottiger M Raniga S von Rechenberg B Zumstein M
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Disturbed muscular architecture, fatty infiltration and muscular atrophy remain irreversible in chronic rotator cuff tears (RCT) even after repair. Poly-[ADP-ribose]-polymerase 1 (PARP-1), a nuclear factor involved in DNA damage repair, has shown to be a key element in the up-regulation of early muscle inflammation, atrophy and fat deposition. We therefore hypothesized that the absence of PARP-1 would lead to a reduction in muscular architectural damage, early inflammation, atrophy and fatty infiltration subsequent to combined tenotomy and neurectomy in a PARP-1 knock-out mouse model.

PARP-1 knock-out (KO group) and standard wild type C57BL/6 (WT group) mice were randomly allocated into three different time points (1, 6 and 12 weeks, total n=72). In all mice the supraspinatus (SSP) and infraspinatus (ISP) tendons of the left shoulder were detached and the SSP muscle was denervated according to a recently established model. Macroscopic muscle weight analysis, retraction documentation using macroscopic suture, magnetic resonance imaging, immunohistochemistry gene expression analysis using real time qPCR (RTqPCR) and histology were used to assess the differences in muscle architecture, early inflammation, fatty infiltration and atrophy between knock out and wild type mice in the supraspinatus muscle.

The SSP did retract in both groups, however; the KO muscles and tendons retracted less than the WT muscles (2.1±21mm vs 3.4±0.41mm; p=0.02). Further assessment of muscle architecture demonstrated that the pennation angle was significantly higher in the KO groups at 6 and 12 weeks (28±5 vs 36±5 and 29±4 vs 34±3; p<0.0001). Combined Tenotomy and neurectomy resulted in a significant loss of muscle mass in both groups compared to the contralateral unoperated side (KO group 62±11% and WT group 52±11%, p=0.04) at 6 weeks. But at 12 weeks postoperatively, there was a significant increase in muscle mass to near normal levels in KO group compared to the WT group (14±6% and 42±7% lower muscle mass respectively; p<0.0001) and less fatty infiltration (12.5 ± 1.82% and 19.6 ± 1.96%, p=0.027). Immunohistochemistry revealed a significant decrease in the expression of inflammatory, apoptotic, adipogenic and muscular atrophy genes at both the 1 week and 6 weeks time points, but not at 12 weeks in the KO group compared to the WT group. This was confirmed by histology.

Our study is the first to show that knocking out PARP-1 leads to decreased loss of muscle architecture, early inflammation, fatty infiltration and atrophy after combined tenotomy and neurectomy of the rotator cuff muscle. Although the macroscopic muscles reaction to injury is similar in the first 6 weeks, its ability to regenerate is much greater in the PARP-1 group leading to a near normalization of the muscle substance and muscle weight, less retraction, and less fatty infiltration after 12 weeks.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_1 | Pages 26 - 26
1 Jan 2017
Kuenzler M Ihn H Akeda M McGarry M Zumstein M Lee T
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Insufficiency of the lateral collateral ligamentous complex causes posterolateral rotatory instability (PLRI). During reconstruction surgery the joint capsule is repaired, but its biomechanical influence on elbow stability has not been described. We hypothesized that capsular repair reduces ROM and varus angle after reconstruction of the lateral collateral complex.

Six fresh frozen cadaveric elbow specimens were used. Varus laxity in supination, pronation and neutral forearm rotation with 1 Nm load and forearm rotaitonal range of motion (ROM) with 0.3 Nm torque were measured using a Microscribe 3DLX digitizing system (Revware Inc, Raleigh, NC). Each specimen was tested under four different conditions: Intact, Complete Tear with LUCL, RCL and capsule tear, LUCL/RCL reconstruction + capsule repair and LUCL/RCL reconstruction only. Reconstruction was performed according to the docking technique (Jones, JSES, 2013) and the capsule was repaired with mattress sutures. Each condition was tested in 30°, 60° and 90° elbow flexion. A two-way ANOVA with Tukey's post-hoc test was used to detect statistical differences between the conditions.

Total ROM of the forearm significantly increased in all flexion angles from intact to Complete tear (p<0.001). ROM was restored to normal in 30° and 60° elbow flexion in both reconstruction conditions (p>0.05). LUCL/RCL Reconstruction + capsule repair in 90° elbow flexion was associated with a significantly lower ROM compared to intact (p=0.0003) and reconstruction without capsule repair (p=0.015). Varus angle increased significantly from intact to complete tear (p<0.0001) and restored to normal in both reconstruction conditions (p>0.05) in 30° and 60° elbow flexion. In contrast varus angle was significantly lower in 90° elbow flexion in both reconstruction conditions compared to intact (both p<0.0001).

Reconstruction of the lateral collateral complex restores elbow stability, ROM and varus laxity independent of capsular repair. Over tightening of the elbow joint occurred in 90° elbow flexion, which was aggravated by capsular repair. Over all capsular repair can be performed without negatively affecting elbow joint mobility.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 544 - 544
1 Sep 2012
Hoppe S Frauchiger L Mainzer J Ballmer P Hess R Zumstein M
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Background

Navigation in total knee replacement is controversially discussed in the literature. In our previous study, femoral component positioning was more accurate with computed navigation than with conventional implantation techniques, however tibial positioning showed similar results. Moreover there were no differences between image-free and image-based navigation techniques. To what extent more accurate femoral positioning has an impact on the clinical mid-term follow up is not known.

Methods

At a mean follow-up interval of 5.3 years, seventy-one patients (84.5%) returned for a review and were examined clinically and radiographically, with use of a methodology identical to that used preop and at 2 years, using the subjective value, the Knee Society Score (KSS), and a.p. and true lateral standard radiographs respectively. Complications, re-operations, persisting pain and resulting range of motion were registered.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 493 - 493
1 Nov 2011
Zumstein M Lesbats V Trojani C Boileau P
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Purpose of the study: Platelet rich fibrin (PRF) favours proliferation of tenocytes and synthesis of extracellular matrix. The purpose of this study was to demonstrate the technical feasibility of adding a PRF envelope during arthroscopic rotator cuff repair to favour short-term vascularisation of the tendon-trochiter zone vascularization.

Material and method: Twenty patients aged over 55 years with a posterosuperior rotator cuff tear were included in this prospective randomized controlled study. The double strand technique was used for all patients. Patients were selected at random for insertion of a PRF envelope between the tendon and the trochiter. There were thus two groups of ten patients. The SSV, SST, VAS and Constant scores were noted. Vascularization was assessed with Power Doppler ultrasound at 6 weeks and 3 months by an independent operator unaware of the study group.

Results: There were no complications during or after the operations. Postoperatively, all patients increased their SSV, SST, VAS and Constant scores significantly. Vascularization of the tendon-trochiter zone, as assessed by Power Doppler, was significantly higher in the PRF group at 6 weeks. It was unchanged in the two groups at 3 months.

Discussion: Arthroscopic rotator cuff repair with adjunction of a PRF envelope is technically feasible and increases vascularizaton of the tendon-trochiter zone at 6 weeks.

Conclusion: PRF can improve the tendon healing rate for rotator cuff tears.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 509 - 509
1 Nov 2011
Vargas P Pinedo M Zumstein M Old J Boileau P
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Purpose of the study: Posterior fracture-impaction of the humeral head (Hill-Sachs defect or Malgainge notch) is a well-known factor of failure for arthroscopic shoulder stabilisation procedures. Recently, Wolf proposed arthroscopic posterior capsulodesis and tenodesis of the infraspinatus, or what we call in French Hill-Sachs Remplissage (filling). We hypothesised that capsule and tendon healing within the bony defect could explain the efficacy of this arthroscopic technique.

Material and methods: Prospective clinical study of a continuous series. Inclusion criteria:

recurrent anterior instability (dislocation or subluxation);

isolated “engaged” humeral defect;

Bankart arthroscopy and Hill-Sachs remplissage;

arthroCT or MRI at least 6 months after surgery.

Exclusion criteria:

associated bone loss in the glenoid;

associated rotator cuff tear.

Twenty shoulders (20 patients) met the inclusion and exclusion criteria and underwent Hill-Sachs remplissage. Four orthopaedic surgeons evaluated independently the soft tissue healing in the humeral defect. Mann-Whitney analysis was used to search for a link between rate of healing and clinical outcome.

Results: Filling of the humeral defect reached 75 to 100% in 16 patients (80%°; it was 50–75% in 4 patients. Healing was never noted less than 50%. The short-term clinical outcome (mean follow-up 11.4 months, range 6–32) showed an excellent results as assessed by the Constant score (mean 92±8.9 points) and the Walch-Duplay score (91 points). The subjective shoulder value (SSV) was 50% preoperatively and 89% at last follow-up. There were no cases of recurrent instability. This study was unable to establish a relationship between minor healing and less favourable clinical outcome.

Discussion: This study confirmed our hypothesis that arthroscopic Hill-Sachs remplissage provides a high rate of significant healing in a majority of patients. Capsule and tendon healing in the humeral defect yields significant shoulder stability via at least two mechanisms:

prevention of defect engagement on the anterior border of the glenoid and

posterior force via improved muscle and tendon balance in the horizontal plane.

Further mid- and long-term results will be needed to establish a confirmed correlation between healing and clinical outcome.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 510 - 510
1 Nov 2011
Boileau P Mercier N Roussanne Y Old J Moineau G Zumstein M
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Purpose of the study: The purpose of this study was to determine the feasibility and reproducibility of a new arthroscopic procedure combining a Bristow-Latarjet lock with Bankart reinsertion of the lambrum.

Material and methods: Forty-seven consecutive patients with significant bone defects in the glenoid and a deficient capsule were treated arthroscopically: arthroscopic Bankart had failed in six. The procedure was performed exclusively arthroscopically using a special instrumentation: after its osteotomy and identification of the axiallary nerve, the coracoids was passed through the subcapular muscle with its tendon; the block was fixed on the scapular neck after 90° lateral rotation so as to prolong the natural concavity of the glenoid. Anchors and sutures were then used to refix the capsule and the labrum onto the glenoid border, leaving the block in an extra-articular position. Follow-up included a physical examination and standard x-rays at 45, 90 and 180 days; 31 patients had a postoperative scan. Three independent operators read the images.

Results: The procedure was completed arthroscopically in 41 of 47 patients (8%); conversion to a deltopectoral approach was required for six patients (12%). The axillary nerve was successfully identified in all shoulders. The block had a subequatorial position in 98% (46/47 shoulders) and equatorial in one. The block was tangent to the surface of the glenoid in 92% (43/47), lateral in one (2%) and too medial (> 5mm) in three (6%). One patient presented an early fracture of the block and five patients exhibited block migration; there was a partial lysis of the block in two patients. The final rate of nonunion of the block was 13% (6/47). Fractures, migrations and non-unions were related to technical errors: screws too short (unicortical) and/or poorly centred in the block.

Conclusion: Our results show that arthroscopic transfer of the coracoids to the scapular neck is a safe and successful operation. The rate of correctly positioned healed blocks was equivalent or superior to conventional techniques. The complications observed show that the arthroscopic block technique is difficult with a long learning curve.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 569 - 569
1 Nov 2011
Old J Boileau P Pinedo M Vargas P Zumstein M
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Purpose: The “Hill-Sachs Remplissage” (HSR) is a procedure used in the treatment of anterior shoulder instability associated with an engaging Hill-Sachs (HS) defect. It consists of an arthroscopic capsulotenodesis of the posterior capsule and infraspinatus tendon within the defect. There is currently no evidence that the capsule and tendon heal in the humeral bone defect. Our hypotheses were

that the capsulotenodesis heals in the HS defect and fills at least 50% of its area; and,

that limitation of range of motion compared to the non-operated shoulder would be minimal.

Method: Prospective clinical study. Inclusion criteria:

recurrent anterior shoulder instability;

engaging HS lesion.

Exclusion criteria:

glenoid bone loss;

rotator cuff tear.

Twenty-nine patients underwent an arthroscopic Bankart repair plus HSR. Clinical assessment at a mean follow up of 13.1 months (range 6 to 32 months) consisted of a structured interview and detailed physical examination including range of motion compare to the contralateral shoulder and instability signs. Range of motion was analyzed in two groups according to length of follow-up, Group 1 with less than 12 months follow-up (14 patients); and Group 2 with greater than 12 months follow-up (15 patients). Either a CT arthrogram (25 patients) or an Arthro-MRI (2 patient) was performed at a minimum of six months postoperatively. Four orthopaedic surgeons analyzed the images independently to determine the percentage of healing of the capsulotenodesis.

Results: There was no recurrence of instability at the latest follow-up. There was no statistically significant deficit in forward elevation in either group. Group 1 patients had statistically significant mean deficits as compared to the contralateral side of 15 degrees of external rotation in adduction (ER1), 15 degrees of external rotation at 90 degrees of abduction (ER2), and 1.1 points of internal rotation in adduction according to the Constant score system (ER1). Group 2 patients had statistically significant mean deficits of 4 degrees of ER1 and 11 degrees of ER2, with no significant difference in IR1. There was healing of the capsulotenodesis within the bone defect in all twenty-seven patients. The bone defect was filled more than 75% of its surface in 22 of 29 patients (76%). The remaining seven had between 50 and 75% filling (24%). There was no defect filling of less than 50% in this study.

Conclusion: We demonstrated greater than 50% HS defect filling in all patients in our series after an arthroscopic “Hill-Sachs Remplissage” and filling > 75% in 22 of 29 (76%). Modest deficits of external rotation were demonstrated at greater than 12 months follow-up. While these results suggest that the technical goal of HS defect filling is achievable, longer term studies are necessary to establish whether there is an association between the rate of healing, the functional impairment of external rotation and clinical outcomes.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 611 - 611
1 Oct 2010
Huber J Dabis E Zuberbühler U Zumstein M
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Introduction: Pain is arguably the most important symptom in the musculoskeletal system. When taking the patient’s history or using patient-questionnaires, pain during activity, at rest and at night are assessed separately, then amalgamated to a composite score. From our experience in regular use of a standardized anamnesis method (interactive anamnesis with Pationnaire), we have gained the impression that pain at rest and night pain might correlate. The aim of this study was to find out if there is a correlation between pain during activity, pain at rest and pain at night.

Patients and Methods: Patients with a variety of disorders of the musculoskeletal system (degenerative pathologies of all major joints, cervical and lumbar spine, multifocal pain syndromes) completed a validated simple patient questionnaire (Pationnaire) during routine consultations. This patient questionnaire allows measurement and documentation of 10 cardinal symptoms and disabilities regarding sleep and normal daily life. All the questionnaires were scanned and filed. The data of more than 1000 observations were statistically analyzed by an external statistical institute for correlations of symptoms using Spearman correlation coefficients.

Results: Included were 938 patients with 1160 observations between October 2006 and June 2008. Average age was 58.9 years, 54% of them were women. Average pain during activity was 59.3, at rest 36.9 and at night 35.6. We found a positive correlation of 0.79 between pain at rest and at night. The correlation coefficient between pain during activity and pain at rest was 0.58, and that between pain during activity and at night was 0.47 (p< 0.05).

Conclusion: Pain at rest and at night, as assessed in a patient questionnaire, are positively correlated. In a questionnaire, these two kinds of pain could be assessed with one single question, i.e. it may be enough to assess and document pain during activity and at rest/night.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 344 - 344
1 May 2010
Zumstein M Frey E Kliesch U Jost B Gerber C
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Background: Progression of fatty infiltration of the suscapularis muscle subsequent to total shoulder arthroplasty is frequent and may be an underestimated problem. The approach with osteotomy of the lesser tuberosity led to consistent bone to bone healing with neither retraction nor overtensioning of the musculotendinous unit. However, in a previous study, fatty infiltration of the subscapular muscle had progressed at least by one stage in 45% of the patients’ shoulders. We hypothesized that anterior approach to the shoulder joint with release of the subscapularis muscle would lead to a direct or indirect subclinical damage of the subscapular nerve and would be an explanation for the progression of fatty infiltration of the muscle.

Methods: Nine Shoulders in eight consecutive patients had received a total shoulder arthroplasty using an anterior approach with osteotomy of the lesser tuberosity. The mean age at time of operation was 67 years. Patients were followed clinically including the Constant score and a detailed neurological examination, as well as radiographically with pre–and postoperative MRI’s, CT’s and standard radiographs at 6–and 12 months thereafter. Neurophysiological assessment was performed using a new pre–intra–and postoperative electromyographic technique for the subscapular muscle. Fibrillation and sharp waves as spontaneuous activities of the motor unit potentials (MUP) indicated direct signs of denervation. Incomplete interference patterns (IP’s) indicated an incomplete innervation pattern as an indirect sign of denervation.

Results: After a one year follow up, 89% of the patients were very satisfied or satisfied with the result. The relative Constant Score improved from an average of 50 percent preoperatively to an average of 96 percent postoperatively (p=0,008). That corresponds to a postoperative subjective Shoulder value of 89 percent. From preoperative to 6–and 12-months postoperative, the average degree of fatty infiltration of the subscapular muscle progressed in an almost significant extent (0.6, 1.1, and 1.6 respectively; p=0.056).

Intra–and postoperatively, there were neither fibrillations and sharp waves of the MUP’s as direct signs, nor incomplete (IP’s) of the motor unit of the subscapular nerve as indirect signs of denervation.

Conclusion: Total Shoulder Arthroplasties perfomed by an anterior approach using an osteotomy of the lesser tuberosity yields good results with a high satisfaction rate. Comparable to our previous study, there are signs of progression of fatty infiltration of the subscapularis muscle within the first year subsequent to total shoulder arthroplasty. However, there were no signs of direct or indirect subclinical damage of the subscapular nerve during total shoulder arthroplasty.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 316 - 317
1 May 2010
Bastian J Zumstein M Tomagra S Bosshard C Schuster A
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Background: The purpose of the study was to evaluate whether anteroposterior translation (APT) after ACL reconstruction with intraoperative balancing of the transplant tension to that of the contralateral ACL could be obtained at follow up. Additionally, differences of APT’s following ACL reconstruction using either autologous patella bonetendon–bone (BTB) or autologous quadriceps-tendon-bone (QTB) were assessed.

Methods: In a consecutive series of 44 patients (44 knees), ACL deficiency was treated in 30 patients (median age: 33, 16–58, 20 male, 22 right knee) with BTB–and in 14 patients (median age: 31, 17–50, 8 male, 10 right knee) with QTB-reconstruction. APT was evaluated in 20° knee flexion in the affected and healthy contralateral knee using the Rolimeter®. Measurements were performed in both knees preoperative, during, and immediately after ACL-reconstrucion, as well as 3, 6 and 12 months postoperatively in triplates. For statistical analysis the non-parametrical Kruskal-Wallis Test (post test: Dunn’s Test) was used.

Results: Statistically significant decreases of APT were observed between pre–and intraoperative measurements in the BTB–and the QTB-group due to ACL reconstruction (11.1±2.0 to 6.3±0.7mm; p< 0.001 in the BTB and 11.1±2.3 to 6.8±1.2mm; p< 0.001 in QTB group). At the intraoperative measurements, there were no differences in APT between the contralateral healthy knee and the reconstructed knee in both groups. During the follow up, significant loss of APT in the balanced reconstructed knees were only observed in the BTB group after 12 months (6.3±0.7 to 7.5±1.2mm; p< 0.05).

Conclusion: After reconstruction of the ACL, BTB–and QTB-ACL reconstruction groups, yielded the same anteroposterior translation (APT) as contralateral healthy knees. This new intraoperative technique provides ACL reconstruction with balancing of the anteroposterior knee translation of the healthy contralateral knee. An increase in APT could be observed 12 months after ACL reconstruction only in the BTB group. Further research is necessary to assess whether QTB-ACL-reconstruction should be preferred regarding preservation of the initial ligament tension at follow up.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 173 - 173
1 Mar 2009
Huber J Ruflin G Pagenstert G Zumstein M
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Introduction: Implant loosening/pseudartrhosis after THR/TKR with large femoral bone defects is associated with pain and immobilization in a wheelchair. In these cases a total femur replacement (Combined total hip and knee replacement connected with an intramedullary rod) can be a therapeutic procedure as known from tumor surgery. We describe this technique and results with in a case serie of patients.

Study Type: Monocentric prospective case serie

Patients and Methods: All patients who had a total femur replacement were followed regularly after 3, 6 months, 1, 3 and 5 years. The follow up was documented with clinical examination, x-rays and validated questionnaires. Indications were loosening after stem revisions (THR), pseudarthrosis and loosening of femoral component after TKR, pseudarthrosis and instability after THR and fracture.

For every case the implants were planned with a total leg x-ray and manufactured (Link). The implants were removed and the knee and hip joint prepared. The approach was performed with two incisions (knee, hip) to reduce the invasivity. The implantation started with the knee implants connected with the intramedullary rod and was finished with the hip implants. Postoperative weight bearing was following pain.

Results: Included were 5 cases of total femur replacement in 4 patients (three women, age from 54 to 69) with a follow up between 12 to 94 months, average 3.5 years. Three cases with stem loosening after THR and revisions before, one case with loosening and pseudarthrosis after TKR, one with pseudarthrosis and instability after THR with femur fracture. Every patient had 2–4 interventions of the affected joint before.

The pain diminuished significant in all patients in the questionnaires and the pain medication could be reduced substantially. All patients gained mobility already three months after the procedure, every patient could walk with crutches. No patients needed to be reoperated in the follow-up period. Every patient could keep the mobility over the the follow-up time. Two patients reported some pain in the knee. Radiologically the defects of the femur were partially consolidated and we could not see further bone loss.

Conclusion: Total femur replacement can be used also in selected patients with large bone defects after arthroplasty (THR/TKN) and loosening or pseudarthrosis. The patients profit from the reduction of pain and the gain in mobility.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 122 - 122
1 Mar 2009
Zumstein M Meyer D Frey E von Rechenberg B Hoppeler H Jost B Gerber C
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INTRODUCTION: Chronic experimental rotator cuff tears are associated with muscle retraction, atrophy, fatty infiltration, a pronounced change in the pennation angle of the muscle and consequent shortening of muscle fibres. It was the purpose of this investigation to study whether slow, continuous elongation of the musculotendinous unit can revert the pennation angle and elongate the shortened muscle fibres.

MATERIAL AND METHODS: The infraspinatus tendons of twelve sheep were released. After retraction of the tenotomised musculotendinous unit, the infra-spinatus was elongated one mm per day using a new elongation-apparatus. After restoring the approximate original length, the tendon was repaired back. Muscular architecture (retraction and pennation angle), fatty infiltration (in Hounsfield units=HU) and muscular cross sectional area (in % of the mean control side) were analyzed at start, at the time before elongation, at the time of repair and six and eighteen weeks thereafter.

RESULTS: In four sheep the elongation failed technically. In the other eight sheep, elongation could be achieved as planned. After retraction of 29mm ± 6 mm after 16 weeks (14% of original length, p=0.008), the mean traction time was 24 days ± 6 days with a mean traction distance of 19 mm ± 4 mm. At sacrifice the mean pennation angle increased in the failed sheep from 30° ± 6° up to 55° ± 14° (p=0.035). In those sheep in which traction was applied, the mean pennation angle was not different to the control side (29.8° ± 7.5° vs. 30° ± 6°, p=0.575). Compared to preoperative, there was a significant increase in fatty infiltration (36 HU, p=0.0001) and decrease of the muscular cross sectional area of 43 % (range 21% to 67%, p=0.0001) at 4 months. In the sheep in which traction could be achieved, fatty infiltration remain unchanged (36 HU ± 6 HU vs 38 HU ± 4 HU, p=0.438) and atrophy decreased by 22% (range 10% to 33%) after 6 weeks of continuous traction (p=0.008).

CONCLUSION: Continuous experimental elongation of a retracted musculotendinous unit is technically feasible and might lead to recovery of the muscle architecture, partial reversibility of atrophy and, arrest of progression of fatty infiltration.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 39 - 39
1 Mar 2009
Zumstein M Simovitch R Lohri E Helmy N Gerber C
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INTRODUCTION: The reverse DELTA III shoulder prosthesis can successfully relieve pain and restore function in cuff tear arthropathy. The most frequently reported complication is inferior scapular notching. The purpose of this study was to evaluate the clinical relevance of notching and to determine the anatomic and radiographic parameters that predispose to its occurrence.

STUDY PROTOCOL: Seventy-seven consecutive shoulders of 76 patients of an average age of 71 years with an irreparable rotator cuff deficiency were treated with a reverse DELTA III shoulder arthroplasty and followed clinically and radiographically under fluoroscopic control for a minimum of 24 months (mean: 44, range: 24 to 96). The effect of glenoid cranial caudal component positioning and of the prosthesis–scapular neck angle on the development of inferior scapular notching and clinical outcome was assessed.

RESULTS: All shoulders which developed notching did so in the first fourteen months. Forty-four percent of the shoulders had inferior scapular notching, 30% had posterior notching and anterior notching (8%) was rare. Osteophytes along the inferior scapula occurred in 27% of the shoulders. The angle between the glénosphère and the scapular neck (r=+0.677)) as well as the craniocaudal position of the glénosphère (r=+0.654) were highly correlated with inferior notching (p< 0.001). A notching index (notching index = height of prosthesis + (prosthesis scapular neck angle x 0.13) was calculated using the height of implantation of the glénosphère and the postoperative prosthesis scapular neck angle: This allowed a prediction of the occurrence of notching with a sensitivity of 91% and specificity of 88%. The height of implantation of the glenosphere had a greater influence on inferior notching than the prosthesis scapular neck angle by a factor of approximately 1:8. Inferior scapular notching was associated with a significantly poorer clinical outcome than absence of inferior notching: At final follow-up, the respective average subjective shoulder values were 62% and 71% (p=0.032), relative Constant scores were 72% and 83% (p=0.028), abduction strength was 4.3 versus 8.7 kilograms (p< 0.001), active abduction was 102° versus 118° (p=0.033) and flexion averaged 110° versus 127° (p=0.004).

DISCUSSION: Inferior scapular notching after reverse total shoulder arthroplasty adversely affects midterm clinical outcome. It can be prevented by optimal positioning of the glenoid component.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 151 - 151
1 Mar 2009
Huber J Schoenenberger P Huesler J Ruflin G Zumstein M
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Introduction: Assessment of symptoms regarding quality, strength and localisation is a part of the medical consultation. After that these informations need to be documented in the medical files. This process can be substantially ameliorated with a patient questionnaire, which assessess the symptoms and disabilities in a structured way. We developed a simple graphic questionaire (pationnaire), clearly structured, easy to understand and simple to fill out. The aim of this study was to test the construct validity of the ‚pationnaire’ with personal interviews (the agreement of symptoms and disabilities), and the ability and time to fill it out without help.

Study design: Monocentric analytical study measuring the agreement.

Persons/patients and methods: The persons/patients were randomly selected by the interviewer. They signed an informed consent approved by the local ethical commitee. After a short introduction about the ‚pationnaire’ and its aims, people filled out one directly without help. The time to completion was measured. The person/patient was then personally interviewed about items within the ‚pationnaire’ to assess their correlation with their symptoms and disabilities, and uncover any sources of misunderstanding or misinterpretation.

At the end of the interview every person/patient was asked for a statement about their understanding, formulations, difficulties with the ‚pationnaire’, missing questions and general impression.

Results: 78 persons/patients (50 women, 28 men) were included. Their average age was 46.3 years (range 12–93 years). 97% (76) could fill out the ‚pationnaire’ without help, 2 needed help and further explanations. Average time for completion was 9.9 min (range 3–45 mins) – the longest time being taken by those who needed help. Complete agreement between the questionaire and the perceived symptoms/disabilities was found in 94% (n=73), it was partial in 3.8% (n=3), and„no agreement“ occurred in 2.2% (n=2, persons, both of whom needed support). The understanding was rated very good in 98% and difficult in 2% (both elderly persons > 80 years). The formulation ’my symptoms are’ was preferred by everybody compared to ’which symptoms do you have’. In general the overall rating was good or very good for all persons, although older people with co-morbidities needed help.