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Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 115 - 115
1 Feb 2003
Zaveri G Ford M Vidmar M
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A retrospective review, comparing outcome following circumferential versus anterior decompression and fusion for patients with cervical spondylotic myelopathy (CSM).

To assess the safety and efficacy of the circumferential operation for CSM.

Cervical spondylotic myelopathy has traditionally been managed by anterior or posterior decompression with/ without fusion. However, there is a considerable variation in neurological recovery and clinical outcome following these procedures. While circumferential decompression and fusion has been shown to provide superior neurological outcome in selected patients with cervical trauma and tumours, its role in the management of CSM has yet to be clearly defined.

Fifteen patients who underwent a 360° operation (Groupl) for CSM were matched (age, number of levels operated and follow-up duration) with patients (Group 2, n=15), that underwent anterior decompression and fusion for the same problem. All patients were operated by a single surgeon and reviewed independently. Charts, radiographs, patient interviews and MODEMS Cervical Spine Outcome questionnaires were the basis for assessment.

The operative time, blood loss, in-hospital stay and post-operative complications were higher in group l. The pseudoarthrosis rate was comparable though a trend towards increased graft and hardware problems was noted in group 2. Neurological improvement as measured by the mJOA Myelopathy Scale was significantly better (p = 0. 039) in group 1. 87% of those in group1 and 67% in group 2 showed improved function. Patients in group1 also performed better (p=0. 056) in the neurological domain and treatment expectation scales of the cervical spine questionnaire, though the incidence of post-op, neck pain was higher.

Single stage circumferential spinal decompression and fusion permits consistent neurological recovery in selected patients with cervical spondylotic myelopathy and it can be performed with limited morbidity.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 115 - 115
1 Feb 2003
Zaveri G Finkelstein J Kreder H Chow E Vidmar M
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A province-wide study designed to use administrative data to determine the rate of post-operative complications, the survival duration and predictors of outcome among patients undergoing surgery for metastatic disease of the spine.

Surgery for patients with spinal metastasis is primarily palliative. It is often fraught with complications, which may in fact diminish quality of life. Quantification of survival rates and the risk of potential complications following surgery is important to the clinician and the patient’s families for decision making.

All patients that underwent surgery for spinal metastasis between 1991 and 1998 were identified using the Ontario health insurance database and a hospital discharge registry.

The mean age at surgery was 60. 3 years (range: 13–92 years). The mortality files identified patients who were dead by October 1999. Information about individual inpatient admissions including post-operative complications was then collected. The survival rates and complications following surgery were quantified and the effect of several variables on these two parameters was computed.

The median and mean survival was 227 days and 793. 4 days respectively. The 30-day and 3-month mortality were 9% and 29% respectively. Advanced age at surgery, male sex, presence of a pre-operative neurological deficit and primary cancers of lung, gastrointestinal tract & melanoma are predictive of poor survival. 39% patients had complications. Pre-operative neurological deficit was associated with a 71% higher risk of developing post-op. wound infection.

In the past, surgery has been recommended in patients with an anticipated survival of at least three to six months. The current study shows that even patients preselected on the basis of predictions of longer survival, there is a potential for early mortality and significant complications. Hence, a careful estimation of the benefits of surgery versus surgery related morbidity must be made prior to offering surgery for palliation.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_III | Pages 340 - 340
1 Nov 2002
Farooq N Zaveri G Freeman BJC Webb JK
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Objective: To evaluate the efficacy and safety of an expandable titanium cage for anterior column replacement after partial or total corpectomy in the thoracolumbar spine.

Design: A retrospective study evaluating the clinical and radiographic outcome following insertion of a novel implant.

Subjects: Twenty-three patients with anterior column insufficiency secondary to tumour, fracture, and infection were treated with a vertebral replacement capable of rapid and controlled in-situ expansion. Follow up consisted of a clinical and radiological review at a mean of 15.2 months (range 6–20 months).

Outcome Measures: The clinical outcome was measured by the degree of pain relief post-operatively, the ability to ambulate and the reliance on walking aids. Neurological deficit was measured using the Frankel Grade. Radiological follow-up compared preoperative radiographs with those taken at maximal follow-up. The degree of kyphosis and the degree of subsidence was measured.

Results: Twenty-three patients with a mean age of 43.6 years (range 20–72) underwent surgery. Indications included metastatic tumour in eight, acute fractures in five, infection in four, degenerative conditions in three, post-traumatic kyphosis in two and pseudathrosis in one. Nineteen patients underwent a single-level corpectomy and four patients a two-level corpectomy. Fourteen patients had a significant neurological deficit preoperatively. Supplementary instrumentation was used in 20 of 23 cases (anterior in nine, posterior in eleven). Excellent pain relief was observed in 19. Ten of 14 patients showed neurological improvement. Eleven patients improved their ambulatory status. There was no hardware failure. An average correction of 110 of kyphosis was observed. The average subsidence was 1.3 mm (range 0.2–2.3).

Conclusions: The use of an expandable vertebral body replacement with supplementary instrumentation following corpectomy appears to be safe and efficacious in correcting kyphosis. This implant appears to have a high resistance to subsidence.