Osteophytes are bony spurs on normal bone that develop as an adaptive reparative process due to excessive stress at/near a joint. As osteophytes develop from normal bone, they are not always well depicted in common imaging techniques (e.g. CT, MRI). This creates a challenge for preoperative planning and image-guided surgical methods that are commonly incorporated in the clinical routine of orthopaedic surgery. The study examined the accuracy of osteophyte detection in clinical CT and MRI scans of varying types of joints. The investigation was performed on fresh-frozen ex-vivo human resected joints identified as having a high potential for presentation of osteophytes. The specimens underwent varying imaging protocols for CT scanning and clinical protocols for MRI. After dissection of the joint, the specimens were subjected to structured 3D light scanning to establish a reference model of the anatomy. Scans from the imaging protocols were segmented and their 3D models were co-registered to the light scanner models. The quality of the osteophyte images were evaluated by determining the Root Mean Square (RMS) error between the segmented osteophyte models and the light scan model. The mean RMS errors for CT and MRI scanning were 1.169mm and 1.419mm, respectively. Comparing the different CT parameters, significance was achieved with scanning at 120kVp and 1.25mm slice thickness to depict osteophytes; significance was also apparent at a lower voltage (100kVp). Preliminary results demonstrate that osteophyte detection may be dependent on the degree of calcification of the osteophyte. They also illustrate that while some imaging parameters were more favourable than others, a more accurate osteophyte depiction may result from the combination of both MRI and CT scanning.
Metal-on-metal hip resurfacing arthroplasty (MoMHRA) has been a popular alternative treatment for young patients with hip osteoarthritis. Despite its advantages over total hip arthroplasty, the use of MoMHRA remains controversial. Achieving the correct positioning of the prosthetic is a concern due to the difficulty and novelty of this procedure. Furthermore, it has been reported that post-operative management using 2D radiographs contains high degrees of variance leading to poor detection of prosthetic malpositioning. In order to compensate for the lack of available technology, current literature has suggested the use of blood metal ion levels as indirect predictors of prosthetic malpositioning due to the abnormal release of metal ions, particularly Chromium and Cobalt, as a result of increase wear and tear. The purpose of this study was to determine whether 2D/3D registration technology can report prosthetic orientation To begin this study, post-operative x-rays (n=72) were used as the two-dimensional media to measure acetabular orientation. Only the acetabular component was examined in this study and acetabular orientation was defined as the function of inclination and version angles. Virtual three-dimensional models of the native, pre-operative pelvises and the acetabular implant were generated and were manually superimposed over the post-operative x-ray images according to anatomical landmarks. A manual 2D/3D registration program was specifically designed for this task. Inclination and version angles of the 2D/3D registered product were measured. Post-operative CT models, which offer the most accurate depiction of the prosthetic
Computer-assisted methods for acetabulum cup navigation have shown to be able to improve the accuracy of the procedure, but are time-consuming and difficult to use. The goal of this project was to develop an easy-to-use navigation technique, requiring minimal equipment for acetabular cup alignment. A preoperative CT scan was obtained, a 3D model of the acetabulum was created, the pelvic plane determined and the cup orientation planned. A registration area, which included the accessible part of the acetabular fossa and the surrounding articular surface, was chosen for the individualised guide. A guidance cylinder, aligned along the planned cup orientation, was attached in the centre of the guide. To transfer the planned alignment information from the registered guide to the impacting of the cup, we developed an intraoperative guidance method based on inertia sensors. The sensors were aligned orthogonal to the central cylinder of the patient-specific guide and the orientation was recorded. At the time of impacting the cup, the sensors were attached to the impactor and the surgeon used the recorded information for the alignment of the impactor.Introduction
Material
Osteochondral autologous autograft (also called mosaic arthroplasty) is the preferred treatment method for very large osteochondral defects in the ankle. For long-term success of this procedure, the transplanted plugs should reconstruct the curvature of the articular surface. The different curvatures between femoral-patella joint and the dome of the talus makes the reconstruction difficult and requires lots of experience. Prior to the surgery a CT arthrogram of the ankle, as well as a CT of the knee were obtained and 3D bone models for the knee, the ankle as well as a model for the ankle cartilage were created. Using custom-made software a set of osteochondral grafts (“plugs”) positioned over the defect site were planned and an optimal harvest location for each plug was chosen. Intraoperatively, an optoelectronic navigation system was installed and sensors were attached to femur, talus, and conventional harvest and delivery chisels. A combined pair-point and surface matching was performed to register femur and talus. For each planned plug the surgeon positioned, oriented, and rotated the harvest and delivery chisels with respect to preoperative plan by using the visual and numerical feedback of the system.Introduction
Material
Femoroacetabular impingement is a condition in which the femoral head/neck region abnormally contacts the acetabulum, limiting the range of motion of the hip and often associated with pain, damage, and loss of function. The pathophysiology of osteoarthritic changes stemming from impingement syndromes has been linked to the shape of the hip; however, little is known about the influence of the soft tissues to this process. In this pilot study, we used computer-assisted navigation technology to track motion on a cadaver that had mild bilateral cam-impingement lesions, and then performed a virtual simulation to locate sites of impingement. We hypothesised that soft tissues contribute to the degree and location of impingement, so we compared impingements across three different dissection states: (i) all soft tissues intact; (ii) post-capsulectomy; with only the labrum and With ethical approval, we used one fresh frozen cadaver pelvis that was sectioned above the fifth lumbar vertebra and at the knee. The femurs and pelvis were implanted with fiducial screws as an accurate means for surface-based image registration. With all soft tissues intact, tissues were imaged using computed tomography with a slice thickness of 0.625 mm. The CT scans were imported into Mimics (v13.0, Materialise, Belgium) and carefully segmented, with particular detail to the articular regions and fiducials, to create 3D digital models of the pelvis and femurs. On each side, optical local coordinate reference (LCR) bodies were attached at the proximal femur and iliac crest to permit spatial tracking with an Optotrak Certus camera (Northern Digital Inc., Waterloo, Canada). The 3D digital models were imported into the VSS navigation system (iGO Technologies, Kingston, Canada) and scrupulously registered to the anatomy using the fiducial screws and a calibrated probe. The pose of the femur and pelvis were recorded throughout a series of twelve movements involving various combinations of flexion-extension, abduction-adduction, internal-external rotation and circumduction, as well as functional movements typical of a clinical hip screening. Soft tissues were selectively removed and the movements were repeated post-capsulectomy and completely disarticulated. The recorded pose data were applied to the 3D digital models to perform a computational simulation of the movements during the trials. The pose data were expressed in coordinates of the anterior pelvic plane to compute angles of motion in the principal directions (flexion, abduction, rotation). The motion data were further filtered so that only comparable ranges of motion were present for data analysis. Algorithms were developed to determine bone-on-bone impingement locations by finding contact points between the models. Impingement locations were plotted on the digital models of the femur and pelvis in order to establish zones of impingement. The surface area of each impingement zone was computed by using a Crust-based algorithm that triangulated impingement points encompassing a region, and then summed the surface area of each triangle to estimate the total impingement surface area. Upon visual inspection, it was immediately apparent that impingements tended to occur in well-defined regions. On the femur, these were found along aspects of the head-neck junction, especially on or near osteophytes. On the pelvis, impingement regions were found along the acetabular rim and extending into the lunate region. With soft tissues intact, both femurs and pelvis had prominent anterior and posterior impingement zones. In contrast, post-capsulectomy impingement zones were predominately confined to the anterior region. It should be noted, however, that the total impingement area decreased post-capsulectomy, representing only about 25% of the total area of impingements when all soft tissues were intact. This was also true in the disarticulated state. Both femurs had mild posterior cam lesions, the right worse than the left. Impingements were seen at these sites with soft tissues intact, but diminished almost entirely post-capsulectomy. The anterior lesions were located With soft tissues intact, impingements tended to occur in external rotation and abduction. With soft tissues removed there was a pronounced shift towards impingements occurring in internal rotation. Impingements were also noted in large flexion angles and large abduction-adduction angles in the absence of soft tissues. Although it is widely accepted that the hip is spherical in shape and has ball-and-socket kinematics, recent work suggests that the osteoarthritic hip is This preliminary study provides a methodology for studying the effects of soft tissue on impingements. We conclude that soft tissues do indeed play an important role in impingement and may even contribute to the development of impingement lesions. Limitations include a small sample size, so further studies are required prior to conclusively establishing impingement patterns in passive kinematics of cadaver hips.
Hip Resurfacing Arthroplasty (HRA) is a surgical technique that has become more popular in recent years for the treatment of hip osteoarthritis in young patients. For these patients, an HRA offers the advantages of preserving the physiologic anatomy of a patient's femoral head size and neck offset, which has been theoretically suggested to improve range of motion and muscle function, as well as preserving bone stock for future revision surgeries. Although the improvements in quality of life outcomes in patients undergoing total hip arthroplasty (THA) are well-documented, there is a lack of literature documenting the improvements in quality of life in patients undergoing HRA. One hundred and four consecutive patients presenting for elective HRA at our institution were recruited between 2004 and 2008 for participation in this study, which was approved by the Ethics Review Board at our institution. The mean age was 51±6y, male:female ratio 79:24 and mean BMI of 29.7±4.4 Preoperative computed tomography (CT) scans were used to preoperatively plan each procedure, and intraoperative procedures were performed using individualized templates [Kunz M, Rudan JF, Xenoyannis GL, Ellis RE. Computer assisted hip resurfacing using individualized drill templates. J Arthroplasty 2010;25(4):600–6]. Surgery time was 90±28 min including time for intraoperative verification of templating accuracy. Mobilization with physiotherapy began within 24 hrs of surgery and continued until the patient was discharged, usually within 2–3 days of surgery. Each patient completed the modified Harris Hip Score (HHS), the UCLA activity rating, the SF-36 mental and physical health score and the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) questionnaires at their preoperative appointment, then at 6 months, 1 year and 2 years postoperative. In addition, radiographs were taken at these appointments to confirm component position, and to check for signs of loosening or heterotopic ossification. Chi-square and t-tests were used for within and between group comparisons on selected variables and across times. Only four patients required revision to THA, with one case of avascular necrosis of the femoral head, one femoral neck fracture and two infections. The mean of the preoperative modified Harris Hip Scores was 51±19.7 with a significant improvement in the mean score at 6 months, 1 and 2 years postoperative (p<0.01). The preoperative UCLA activity index averaged 4 (range 2–9), improving to a mean of 6 at 6 months (p<0.001) then at 1 to 2 years to 7 (p<0.001). Mental state and further assessment of physical function were performed using the SF-36 scores, with the physical score initially 27.5 and improving to 45.2 after 2 years (p<0.01). The mental component score (MCS) means were almost unchanged, from 50.3 preoperatively to 51.5 after 2 years (p<0.21). Further data processing showed that patients who began with a below-average mental score also had significantly worse WOMAC scores for pain, stiffness and function; these patient showed a significantly higher MCS at 2 years (p<0.05). Those whose MCS were above average preoperatively showed little difference after 2 years.MATERIALS AND METHODS
RESULTS
The purpose of this study was to compare the accuracy and precision of acetabular component placement in cadavers using conventional techniques and CT-based individualised guides by both orthopaedic trainees and surgeons. Seven cadaveric pelvises underwent a computerised tomography (CT) scan and a three-dimensional virtual model was created. Based on this model, cup orientation was planned for 40 degrees of inclination and 20 degrees of anteversion and an individualised guide was designed. A physical model of the individualised guide was created using a Rapid Prototyping machine (dimension SST, Stratasys, Inc., USA). The pelvises were mounted in the lateral position and covered with a soft tissue envelope exposing only the acetabulum as would be visualised during a lateral approach to the hip. A total of 26 participants (16 orthopaedic surgery residents, 10 orthopaedic surgeons) were asked to use an acetabular cup impactor to place the cup in 40 degrees of inclination and 20 degrees of anteversion. This was first completed for all seven pelvises using conventional placement. Each participant was then instructed on how to use the individualised guide. They were provided with the guide and an individualised acetabular model to practice placement. Once they were comfortable with the system they were then asked to use the individualised guides in each of the seven pelvises. An optoelectronic navigation system was used to evaluate the accuracy of the placement of the acetabular cup. An Optotrak Certus Motion Tracking System (Northern Digital Inc., Waterloo, Canada) was used. An optoelectronic marker was attached to the acetabulum and a combined pair-point and surface matching was performed. After the guide was placed in the acetabulum, a tracked axial pointing device was aligned inside the guidance cylinder and its three-dimensional orientation stored. The angle deviation between the achieved position and the planned cup orientation was calculated. There were no statistically significant differences between trainees and surgeons in either conventional placement or use of the individualised guides. There were no statistically significant differences in anteversion between the groups. The individualised guide showed statistical improvement in the absolute deviation from planned inclination compared to conventional placement (4.2° vs. 9.1°, p< 0.001) as well as a reduction in standard deviation (3.3 vs. 5.9, p< 0.001). The use of individualised guides can improve the accuracy and precision in the placement of acetabular component positioning. The current guide design controls well for inclination, which is a key factor in the function of a total hip arthroplasty. Based on this data, we will implement design changes to better address version of the component. Future work will likely include comparison to computer-assisted cup placement as well.
For hip resurfacing arthroplasty, precise planning and implantation of the components is necessary for long-term success. Earlier studies have shown that a computer-assisted technique can achieve higher accuracy than conventional technique. However, many of the proposed computer systems add additional complexity, time and cost to the surgery. This study investigated the use of rapid prototyping as an accurate, fast and cost-effective solution for computer-aided hip resurfacing. From a CT scan of each patient, a 3-dimensional computer model of the proximal femur was produced and the drilling trajectory for the central pin of the stem was planned. To transfer this plan to the patient, surface-matched plastic drilling templates were created using a rapid prototyping machine. Depending on the surgical approach, these templates contained a mirror-image of parts of the anterior or posterior femoral head and neck. These mirror-image templates helped to exactly position the drilling guide on the bone during surgery, which ensures a precise transformation of the preoperative plan into the surgical field. To test the accuracy and reproducibility of this system, we created plastic models of three cadaver femurs using the rapid prototyping machine. For each of these femurs one anterior and one posterior drilling template were generated. Each template was applied three times to the femur model and the direction of the drilling target was recorded and axis deviations measured. The average deviation between the planned and the template-guided drill direction was 1.3° for the anterior approach and 1.2° for the posterior approach. The reproducibility for the drilling axis was measured for the anterior approach as 0.4° and posterior 0.3°. In comparison to previous published results for computer-assisted hip resurfacing, our results show similar or better accuracy. Further in-vitro and in-vivo experiments will be performed to obtain statistically significant accuracy measurements and intraoperative feasibility tests. Our early results show great potential for this technique for accurate and in-expensive guidance for hip resurfacing.
Hip resurfacing has recently become an alternative for total hip replacement, especially for younger and more active patients. Although early results are encouraging, there are reports of failure as a result of malpositioning of the femoral component. To help overcome this problem we developed a CT-guided computer-assisted system for the planning and guidance of the femoral component during hip resurfacing. 3D isosurface models were generated from a CT scan of the pelvis and proximal femur. By superimposing virtual prosthetic components, the surgeon preoperatively determined the size, position and orientation of the femoral component. Intraoperatively, an optoelectronic navigation system was used for realtime CT-guidance of the insertion of the alignment pin for the femoral component. In a laboratory study, the precision of the intraoperative guidance system was investigated. One experienced and one inexperienced surgeon performed one posterior and one anteriolateral approach on 10 different plastic bone models. After each procedure, the alignment-pin orientation was compared to the planned orientation. In a preliminary clinical study, 27 patients underwent the computer-assisted method and 13 patients were operated on using conventional technique. Both posterior and anteriolateral surgical approaches were used. Pre-operative and postoperative neck-shaft angles were compared using Student’s t-test. In the laboratory study, the mean deviations between planned and navigated alignment-pin orientation was 0.65° (StDev 0.9°) for the experienced surgeon, and 0.13° (StDev 0.7°) for the inexperienced surgeon. The mean deviation of anteversion angles were measured as 0.31° (StDev 0.8°) for the experienced surgeon and 0.01° (StDev 0.9°) for the inexperienced surgeon. In the clinical study, we measured the neck-shaft angle in the computer-assisted group to be an average of 133° preoperatively and 134° postoperatively (p=0.16), and in the conventional group to be an average of 136° pre-operatively and 135° postoperatively (p=0.79). There were no significant differences between pre-operative and post-operative measurements between the groups. However, there was a significantly lower standard deviation in the postoperative computer-assisted group: it was 6.6°, compared to 13.3° in the conventional group (Levene’s test for equality of variances, p=0.004). We conclude, based on our results, that a CT-guided system can help to prevent femoral misalignment during a hip resurfacing by increasing the intraoperative precision.
We developed a computer assisted total knee arthroplasty system to help the surgeon achieving more intra-operative accuracy.