This aim of this study was to identify common factors in patients with the shortest length of hospital stay following total hip arthroplasty (THA). This would then allow a means of targeting suitable patients to reduce their length of stay. This was a retrospective cohort study of all patients undergoing primary THA at our institution between September 2013 and August 2014. Demographic data were collected from the patient record. The cohort was divided into those discharged to home within two days of operation and the rest of the THA population. The demographics (age, gender, ASA grade, body mass index (BMI), primary diagnosis, socioeconomic status (Scottish Index of Multiple Deprivation, SIMD and SIMD health domain) were compared between groups. In addition for the early discharge group information on comorbidities, family support at home and independent transport were collected. The study cohort was 1292 patients. 119 patients were discharged home on the first post-operative day. Those discharged earlier were on average younger (p<0.0001), more likely to be male (p<0.0001) and had a lower ASA grade (p<0.00001). Other demographics did not differ between groups. Patients who were discharged early also appeared to have few comorbidities (Diabetes 5.9%, Cardiac disease 7.6%, Respiratory disease 9%), high levels of family support at home (95%) and high levels of independent transport arrangements (97%). Factors associated with those patients with the shortest lengths of stay were identified. Such factors could be used to target patients who are suitable for streamlined recovery programmes aimed at early discharge after THA and assist with service planning.
There has not been any published work quantifying the volume cement used/needed for knee arthroplasty. The number of mixes of cement used is at the discretion of the surgeon, based on their own experience/training. The objective of this study was to quantify the volume of cement used for knee arthroplasty in our institution, and to observe variations between surgeons and implant size. The study then aimed to calculate the theoretical volumes required and observe the volume of cement actually implanted before commenting on cost implications of cement usage. Prospective data for 85 consecutive knee arthroplasties performed by 9 consultants was examined. A single mix in this institution refers to 40g of Palacos R+G. Significant variation between surgeons was seen, with a range of one to three mixes being used. Several surgeons used one mix exclusively, independent of implant size, whilst others exclusively used two mixes. The departmental average was 1.4 mixes per knee. The total surface area of our largest implants (Size 8 Triathlon Femoral and Tibial components) was measured-108cm2 and compared to the volume of a single mix of cement −49 cm3. Even using the largest component size, a single mix will provide 4.5mm of uniform cement coverage. The volume of cement actually implanted during 10 knee arthroplasties was examined by weighing the residual cement. The average volume of cement implanted was 18cm3 per knee. In 2009 1085 knee replacements were performed in this institution. If all surgeons in the department used a single mix of cement this could potentially save £16,357.46 per year. (Presuming average usage was 1.4 mixes per knee, 434 ‘extra’ mixes were used, costing £37.69 each) We conclude that a single mix of cement will cover the area required for all Triathlon implants and that less than half a mix (on average) is actually implanted.
Previous work has demonstrated vulnerability of the femoral nerve to damage by anterior acetabular retractors during THA. The aim of this study was to quantify the proximity of the femoral nerve to the anterior acetabulum, on cadaveric material and MRI studies. A standard posterior approach to the hip was carried out in 6 fresh frozen cadaveric hemipelves. Following dislocation and removal of the femoral head, measurements were taken from the anterior acetabular lip to the posterior aspect of the femoral nerve as it passed over this point. 14 MRI studies of the hip were obtained from the local PACS database (7 male, 7 female; mean age 58 (range 32–80)). T1 weighted axial scans were reviewed. Measurements were obtained from the anterior acetabular lip to the posterior surface of the femoral nerve and artery, and the cross-sectional area of iliopsoas was calculated. There was no significant difference between the mean distances to the femoral nerve in the cadaveric (24 mm) and MRI groups (25.3mm) (p=0.7). On MRI images, the distance between the acetabular wall and both the femoral artery (p=0.003) and femoral nerve (p=0.007) was significantly larger in men. The femoral artery is strikingly close to the acetabulum in females, passing a mean distance of 14.8 mm, whereas in males this was 23.9 mm. The mean femoral nerve distance was 28.7 mm in males and 21.9 mm in females. The cross-sectional area of iliopsoas was significantly smaller in women (5.97 cm2 compared to 11.37 cm2, p<0.001). Both the femoral artery and nerve run in close proximity to the anterior acetabular lip. Care should be taken when placing instruments in this area to avoid neurovascular injury. The increased incidence of femoral nerve damage in women following THA may be due to the significantly smaller bulk of iliopsoas.
Acetabular retractors have been implicated in damage to the femoral and obturator nerves during total hip arthroplasty (THA). Despite this association, the anatomical relationship between retractor and nerve has not been elucidated. A posterior approach to the hip was carried out in 6 fresh frozen cadaveric hemi- pelvises. Large Hohmann acetabular retractors were placed anteriorly over the acetabular rim, and inferiorly, as per routine practice in THA. The femoral and obturator nerves were identified through dissection and their relationship to the retractors was examined. If contact with bone was not maintained during retractor placement, the tip of the anterior retractor had the potential to compress the femoral nerve, by passing either superficial to, or through the bulk of the iliopsoas muscle. If pressure was removed from the anterior retractor, the tip pivoted on the anterior acetabular lip, and passed superficial to iliopsoas, overlying and compressing the femoral nerve, when pressure was reapplied. The inferior retractor pierced the obturator membrane, medial to the obturator foramen in all specimens. Subsequent retraction resulted in the tip moving laterally to contact the obturator nerve. Both the femoral and obturator nerves are vulnerable to injury around the acetabulum through the routine placement of retractors in THA. The femoral nerve is vulnerable where it passes over the anterior acetabulum. Iliopsoas can only offer protection if the retractor passes deep to the muscle bulk. If pressure is removed from the anterior retractor intra-operatively it should be reinserted. The obturator nerve is vulnerable as it exits the pelvis through the obturator foramen. Vigorous movement of the inferior retractor should be avoided. Awareness of the anatomy around the acetabulum is essential when placing retractors.
Component malalignment has long been implicated in poor implant survival in Total Knee Arthroplasty (TKA). Malalignment can occur in orientation of bony cuts, and in component cementation/implantation. Several systems exist to aid bony cut alignment (navigation, shape matching), but final implantation technique is common to all TKA. Correction of errors in bony cut alignment at cementation/implantation by surgeons has been described. Changes in alignment at this stage are likely to result in asymmetrical cement penetration, which is implicated in early failure. This study reviewed a consecutive series of 150 primary cemented TKAs using an imageless navigation system (aiming for neutral overall limb alignment). Deviation at implantation was calculated by comparing limb alignment recorded using the trial components with limb alignment recorded with the final implanted components, prior to closure. 136 patients (91%) had a final overall limb alignment within 2° of neutral. Three patients (2%) had a final overall limb alignment greater than 3° from neutral. Deviation occurring at implantation is shown in Figure 1 with deviations distributed around zero (mode 0, median 0.3, range −2 to +4,)
In this study we aimed to identify which anatomical site was the most effective for methicillin resistant staphylococcus aureus (MRSA) detection within an elective orthopaedic setting. A retrospective review was performed of 13,373 elective orthopaedic patients from pre-assessment and admission screening swabs taken over a five year period (2005-2010). Swabs were taken from the nose, the axilla and either the groin or perineum. MRSA was identified in 136(1.02%) of patients. The nose was found to be positive for MRSA in 89.6% of cases identified. Therefore only 10.4% of the MRSA carriers (0.1% of all admissions) would not have been identified had a single nasal swab been taken. There was no additional benefit in swabbing the axilla. We believe that for the majority of orthopaedic elective admissions a single nasal swab should be sufficient. In hip arthroplasty patients it may be beneficial to additionally swab the groin given the close proximity of the surgical wound.
Patients undergoing total knee arthroplasty (TKA) experience significant post-operative pain. We report the results of a new comprehensive patient care plan to manage peri-operative pain, enable early mobilisation and reduce length of hospital stay in TKA. A prospective audit of 1081 patients undergoing primary TKA during 2008 and 2009 was completed. All patients followed a planned programme including pre-operative patient education, pre-emptive analgesia, spinal/epidural anaesthesia with propofol sedation, intra-articular soft tissue wound infiltration, post-operative high volume intermittent ropivacaine boluses with an intra-articular catheter and early mobilisation. The primary outcome measure was the day of discharge from hospital. Secondary outcomes were verbal rating pain scores on movement, time to first mobilisation, nausea and vomiting scores, urinary catheterisation for retention, need for rescue analgesia, maximum flexion at discharge and six weeks post-operatively, and Oxford score improvement. The median day of discharge to home was post-operative day four. Median pain score on mobilisation was three for first post-operative night, day one and day two. 35% of patients ambulated on the day of surgery and 95% of patients within 24 hours. 79% patients experienced no nausea or vomiting. Catheterisation rate was 6.9%. Rescue analgesia was required in 5% of cases. Median maximum flexion was 85° on discharge and 93° at six weeks post-operatively. Only 6.6% of patients had a reduction in maximum flexion (loss of more than 5°) at six weeks. Median Oxford score had improved from 42 pre-operatively to 27 at six weeks post-operatively. The infection rate was 0.7% and the DVT and PTE rates were 0.6% and 0.5% respectively. This multidisciplinary approach provides satisfactory post-operative analgesia allowing early safe ambulation and discharge from hospital. Anticipated problems did not arise, with early discharge not being detrimental to flexion achieved at six weeks and infection rates not increasing with the use of intra-articular catheters.
Patients undergoing total knee arthroplasty (TKA) experience significant postoperative pain. This impedes early mobilization and delays hospital discharge. A prospective audit of 1081 patients undergoing primary TKA during 2008 was completed. All patients followed a programme including preoperative patient education, pre-emptive analgesia, spinal/epidural anaesthesia with propofol sedation, intra-articular soft tissue wound infiltration, postoperative high volume ropivacaine boluses with an intra-articular catheter and early mobilization. Primary outcome measure was length of stay. Secondary outcomes were verbal analogue pain scores on movement, time to mobilization, nausea and vomiting scores, urinary catheterization for retention, need for rescue analgesia, range of motion at discharge and six weeks postoperatively. The median day of discharge was postoperative day four. Median pain score on mobilization was three for first postoperative night, day one and two. 35% of patients ambulated on the day of surgery and 95% of patients within 24 hours. 79% patients experienced no nausea or vomiting. Catheterization rate was 6.9%. Rescue analgesia was required in 5% of cases. The median day of discharge was postoperative day four. Median range of motion was 85° on discharge and 93° at six weeks postoperatively. This comprehensive care plan provides satisfactory postoperative analgesia allowing early safe ambulation and discharge.
Arthritic knees, for the purpose of surgical correction during arthroplasty, are generally thought to be either varus knees or valgus knees and soft tissue releases are done in accordance with the same concept. This view is dependent on the clinical deformity in extended knee and the plain AP radiograph of the extended knee. This concept is now challenged by the observations from our study of the arthritic knee kinematics using computer aided navigation when performing total knee replacement arthroplasty. We performed 283 total knee replacements with computer aided navigation. Imageless navigation was used with Stryker and Orthopilot systems. Bone trackers were fixed to the bones and through real time infrared communication the data was collected. The knee kinematics were recorded before and at the end of surgery. This included measurement of biomechanical axis with the knee extended and then gradually flexed. The effect of flexion on the coronal alignment was recorded real time on the computer. The results were then analysed and compared with plain radiographic deformity on long leg films. Majority of the knees did not behave in a true varus or valgus fashion. We classified the deformity into different groups depending on the behavior of the knee in coronal plane as it moves from extension to flexion. 2 degree was taken as minimum deviation to signify change, as the knee bends from full extension to flexion. The classification system is as follows
Deformity - Varus/Valgus to start with in extension
Deformity remains the same as the knee flexes Increasing deformity as the knee flexes
Decreasing deformity but does not reach neutral in flexion Decreasing deformity reaches neutral in flexion
Decreasing deformity and crosses to opposite (Varus to valgus or valgus to varus) deformity in flexion
Deformity first increases and then decreases but does not reach neutral Deformity first increases and then decreases to neutral Deformity first increases and then decreases to cross over to opposite deformity in flexion Traditional releases of medial or lateral structures without realising the true picture of what happens when the knee is flexed, may not be correct. From our study it is clear that not all arthritic varus or valgus knees behave in the same way. Some of the releases we perform conventionally may not be required or need to be modified depending on the knee kinematics.
Computer-assisted surgical techniques in knee replacement procedures have been shown to increase the accuracy of implant positioning and reduce the incidence of alignment and soft-tissue balancing “outliers”. The use of this technology as a training tool is less widely reported. However, the recent implementation of the EWTD 48-hour working week for junior doctors has focussed attention on the issues of surgical training and experience. Recent evidence from trainee logbooks has shown a significant downward trend in operative exposure and this is forcing changes in the principles of how training should be delivered. Trainees are actively required to demonstrate operative competence in order to progress but are increasingly faced with limited opportunities to acquire these skills. On the other hand, trainers also face difficulties with the prospect of supervising less accomplished trainees which raises ethical issues of patient protection. We present a trainee’s perspective of experience gained in a unit routinely using computer-assisted technology and highlight the potential to enhance the learning process. Navigation systems provide constant visual and numerical feedback via a computer simulated interpretation. Initially this displays relevant functional anatomy, helps in the identification of anatomical landmarks and demonstrates sagittal and coronal plane deformities which can be difficult to accurately assess “by eye”. Computer-assisted systems have the benefit of displaying only bony anatomy which improves visualisation. This can then be compared to the palpable, clinical deformity on the table. The geometry of the native knee is also made clear with the navigation system leading to a better understand of the objectives of TKR. There are some aspects of the biomechanics of the knee which are difficult to appreciate, such as the changes in varus-valgus alignment during flexion and extension. This may be very subtle and difficult to pick up manually but can look quite dramatic on the computer. The position of cutting jigs which are held to the bone by pins can be altered by inadvertently lifting or hanging on them with the saw, when making the bone cuts. Additionally the cut can be altered by advancing the cutting block closer to the bone, for example if cutting the tibia with a posterior slope. Both these effects can be quantified by using the navigation tools to confirm the cut that has been made. Trainers can have the benefit of seeing the alignment and confirming the cuts made by a trainee without having to get closely involved with the operation. Cementation technique is also open to scrutiny with the ability to compare pre and post cementation alignment. The positive feedback obtained from computer assisted surgery is educational to the trainee, by giving an undisputable computer generated graphic of what they are doing during the different stages of total knee arthroplasty. It also shows what has been achieved at the end of the procedure. This can give both the trainer and trainee more confidence in the procedure and ensures patient safety.
The recent introduction of intra-articular local anaesthetic techniques following total joint arthroplasty have demonstrated improvements in post-operative pain control, early joint mobilisation and may contribute to early discharge. Following intra-operative infiltration, the CALEDonian Technique requires ropivicaine to be administered postoperatively via an epidural catheter and filter, 20 to 40 ml over 60 seconds, on three occasions. Epidural filter catheters are used to prevent bacterial contamination during injection and have demonstrated 100% efficacy when intact. However, on internal departmental audit we have become aware of a filter membrane rupture rate approximating 10%. We therefore investigated the variables of syringe size and rate of administration in the occurrence of filter ruptures. Using a standard primed epidural catheter set (Perifix B Braun), pressure measurements were taken pre- and post-filter. Recordings using the filter with attached catheter tubing were undertaken using 5 ml, 10 ml and 20 ml syringes (n=10) during infusion of a standard 5 ml volume. Controlled (over 1 min and following departmental protocol) and forced (over less than 15 seconds) infusions were undertaken manually and the experiment also undertaken using an automated syringe driver with 40 ml infused at a rate of 400 ml/hr. Each experiment was repeated ten times. Infusion pressures were measured and filters examined for evidence of rupture. Using departmental protocol, controlled infusions independent of syringe size generated consistently low pressures, averaging 115 kPa, with no filter ruptures. Forced administration, independent of syringe size, generated pressures averaging 625.1 kPa. This is above the filter threshold and resulted in almost universal filter rupture. An automated device infusing at a rate of 400 ml/hr again generated low pressures and no filter ruptures. Our study demonstrates low infusion pressures and no filter ruptures, independent of syringe size, when departmental protocol is adhered to suggesting that a human element may be in-part responsible for filter rupture. Although the technique currently used is safe, our audit has raised awareness of a potential difficulty and has lead to re-education of staff involved in this process. Consideration is being given to the possibility of automating infusions in the future and a process of re-audit of filter rupture will be undertaken.
A total of 305 TKAs with complete data sets were included in the analysis. Of these 36% were mobilised on the day of surgery and 93% by post-operative day 1. Catheterisation rates were 12% and the need for postoperative intra-venous fluids was 10%. In-house physiotherapy discharged 58% of patients by day 3 and 85% by day 5. The visual analogue pain scores (on movement) on day zero and day one were within acceptable limits (median = 3) and 80% of patients experienced no nausea or vomiting. Functionally, the median range of movement at discharge was 85° with 31% of patients requiring out-patient physiotherapy assessment. At six weeks the median range of motion was 95° with only 5% of patients having a reduced range of motion (reduction of >
10°) when compared to discharge. The median Oxford scores improved from 43 pre-operatively to 26 at six weeks.
Short leg radiographs remain the standard radiographs available in many UK hospitals. The aim of this study was to see if these radiographs are reliable when assessing the post-operative alignment of total knee arthroplasty in comparison to a Hip-Knee-Ankle (long leg) radiograph. Twenty consecutive 6 week post-operative long leg radiographs, taken with a standardised protocol, and a short leg radiograph derived from the same digital image were each examined on two separate occasions by two observers. On the long leg radiograph the anatomical and mechanical axis were calculated and on the short leg radiograph the anatomical and surrogate mechanical axis were calculated. These data were used to investigate intra- and inter-observer error. A single observer also collected the same measurements on an additional 30 radiographs (total of 50) to further investigate any patterns of error. On long leg radiographs, intra-observer agreement was good for both anatomical and mechanical axis for both observers (Intraclass Correlation Coefficients [ICC] of 0.95 to 0.98). The anatomical axis on short leg radiographs was also good (ICC = 0.92 and 0.76). Intra-observer agreement for the short leg radiograph derived mechanical axis was not as consistent (ICC = 0.73 and 0.56). Inter-observer variability was good for long leg radiographs for both anatomical (ICC = 0.89) and mechanical (ICC = 0.95) axis. On short leg radiographs, however, agreement was not as good, in particular for the mechanical axis (ICC = 0.51), but also the anatomical (ICC = 0.73). Taking the long leg radiograph values as the “gold standard” there was a difference in the magnitude of errors seen on short leg radiographs dependant on the knee alignment. Varus aligned knees (n=24) had an average error of 1.2° (0° to 3°) for the anatomical axis and 1.6° (0° to 4°) for the mechanical axis. Perfectly aligned knees (n=8) had an average error of 3.0° (1° to 6°) for the anatomical axis and 2.9° (1° to 5°) for the mechanical axis. Valgus aligned knees (n=18) had an average error of 3.4° (0° to 8°) for the anatomical axis and 5.8° (2° to11°) for the mechanical axis. Using a Mann-Whitney test the magnitude of error was greater for valgus knees for both anatomical (p<
0.0001) and mechanical (p<
0.00001) axes when compare to varus knees. Interestingly all except one knee measured on the long leg radiograph as valgus aligned appeared to be in varus on the short leg radiograph. In conclusion, short leg radiographs are inadequate to make any comment on leg alignment in total knee arthroplasty. This is most pronounced in a valgus aligned knee.
One previous study has suggested that the computer-assisted technique may reduce blood loss in comparison to traditional methods. This study ( Our study uses a more accurate method of assessing blood loss, and the sample size is larger (n=136; 68 standard TKR versus 68 computer assisted TKR).
Total body blood volume was calculated using the formula of
Our study found that overall blood loss was less for both groups, when compared to the findings of Kalairajah Y et al. We suspect that this difference was due to our departmental policy that all patients receive tranexamic acid at the start of joint replacement procedure.
Performing Total Knee Replacement (TKR) surgery using computer assisted navigation systems results in more reproducibly accurate component alignment. Navigation allows real time evaluation of passive knee behaviour throughout flexion. These kinematic measurements reflect tibial rotation about the femoral condyles, patellar tracking and soft tissue balance throughout surgery. In this study, we aim to study dynamic knee function in navigated and standard instrumentation TKR patients performing a range of everyday activities using gait analysis. A prospective randomised controlled trial evaluated the functional outcome using gait analysis with 20 patients in each of three groups – Standard, Navigated and Control. The same implant (Scorpio) and navigation system (Strykervision) was used for each patient. The control group were subjects with no history of knee pathology or gait abnormality. Using an 8-camera Vicon motion analysis system set at 120Hz (real-time motion), we assessed the following functional activies: walking, rising from/sitting in chair, ascending/descending stairs. One functional outcome measure we have analysed so far is the maximum flexion angle. The maximum flexion angle was recorded for each activity in standard, navigated and control groups respectively. ANOVA was performed, with significance set at p<
0.05. Maximum flexion angle during gait was 65.6°, 72.6° (p=0.009) and 73.5° (p=0.74), chair rising/sitting was 82.5°, 92.8° (p=0.01), and 93.5° (p=0.64), stairs ascent/descent was 81.8°, 99° (p<
0.0001), and 113.4° (p<
0.0001). In terms of dynamic functional outcome, we found that the average maximum flexion angle for the navigated group was greater than for the standard group; moreover, this was similar to the maximum flexion angle for the control group when performing a variety of normal daily activities.