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Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_10 | Pages 2 - 2
1 Oct 2020
Gross AE Backstein D Kuzyk P Safir O Iglesias SL
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Patients with longstanding hip fusion are predisposed to symptomatic degenerative changes of the lumbar spine, ipsilateral knee and contralateral hip1. In such patients, conversion of hip arthrodesis to hip replacement can provide relief of such symptoms2 – 4. However, this is a technically demanding procedure associated with higher complication and failure rates than routine total hip replacement.

The aim of this study was to determine the functional results and complications in patients undergoing hip fusion conversion to total hip replacement, performed or supervised by a single surgeon.

Twenty-eight hip fusions were converted between 1996 and 2016. Mean follow up was 7 years (3 to 18 years). The reasons for arthrodesis were trauma 11, septic arthritis 10, and dysplasia 7. The mean age at conversion was 52.4 years (26 to 77).

A trochanteric osteotomy was performed in all hips. Uncemented components were used. A constrained liner was used in 7 hips. Heterotopic ossification prophylaxis was not used in this series.

HHS improved a mean of 27 points (37.4 pre-op to 64.3 post-op). A cane was used in 30% of patients before conversion and 80% after.

Heterotopic ossification occurred in 12 (42.9%) hips. There was 2 peroneal nerve injuries, 1 dislocation, 1 GT non-union and 1 infection.

There have been 5 revisions; 2 for aseptic loosening, 1 for infection, 1 for recurrent dislocation and 1 for leg length discrepancy.

Conversion of hip fusion to hip replacement carries an increased risk of heterotopic ossification and neurological injury. We advise prophylaxis against heterotropic ossification. When there is concern about hip stability we suggest that the use of a constrained acetabular liner is considered. Despite the potential for complications, this procedure had a high success rate and was effective in restoring hip function.


Bone & Joint 360
Vol. 1, Issue 5 | Pages 34 - 34
1 Oct 2012
Gross AE


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVIII | Pages 106 - 106
1 Sep 2012
Masri BA Garbuz DS Duncan CP VGreidanus N Bohm E Valle CJD Gross AE
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Purpose

Dislocation after revision total hip is a common complication. The purpose of this study was to assess whether a large femoral head (36/40mm) would result in a decreased dislocation rate compared to a standard head (32mm).

Method

A randomized clinical trial was undertaken to assess the effect of large femoral heads on dislocation after revision total hip. Patients undergoing revision hip arthroplasty at seven centers were randomized to 32mm head or 36/40mm head. Patients were stratified according to surgeon. Primary endpoint was dislocation. Rates were compared with Fishers exact test. Secondary outcome measures were quality of life: WOMAC, SF-36 and satisfaction. One hundred eighty four patients were randomized: 92 in the 32mm head group and 92 in the large head group. Baseline demographics were similar in the two groups. Patients were followed from two to five years postoperatively


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVIII | Pages 94 - 94
1 Sep 2012
Kosashvili Y Serendono JS Ben-Lulu O Safir O Gross AE Backstein D
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Purpose

Two-stage re-implantation after infection of Total Knee Arthroplasty (TKA), remains the gold standard to which other forms of treatment should be compared. The primary purpose of this study was to determine the rates of failure and functional outcome of two stage revision TKA for treatment of infection comparing cemented posterior stabilized compared to constrained condylar implants.

Method

The study group included 25 consecutive patients who had two stage revision TKA to treat infection with an average follow up of 3.25 1.5 years (range 2–6). In all patients the diagnosis of infection was made using standard serum parameters as well as aspiration for joint fluid analysis. Eight patients had posterior stabilized TKAs and 17 patients with had constrained condylar TKAs. Clinical evaluation included the Knee Society Knee Scores (KSKS) at each follow-up visit as well as a detailed record of any difficulties or complications.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVIII | Pages 26 - 26
1 Sep 2012
Zywiel MG Kosashvili Y Gross AE Safir O Lulu OB Backstein D
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Purpose

Infection following total knee arthroplasty is a devastating complication, requiring considerable effort on the part of the surgeon to eradicate the infection and restore joint function. Two-stage revision is the standard of care in the treatment of peri-prosthetic infection, using a temporary antibiotic-impregnated spacer between procedures. However, controversy remains concerning the use of static versus dynamic spacers, as well as the spacer material. The purpose of this study was to evaluate the clinical outcomes and complications of two-stage revision total knee arthroplasty in patients treated with a metal-on-polyethylene articulating spacer, as compared to those treated with a static antibiotic-impregnated cement spacer at the same centre.

Method

Twenty-seven knees in patients with a mean age of 65 years (range, 40 to 80 years) were treated with two-stage revision of an infected total knee arthroplasty using a metal-on-polyethylene dynamic prosthetic spacer fixed with antibiotic-impregnated cement. Clinical outcomes were evaluated using maximum active knee range of motion, as well as modified Knee Society knee scores and incidence of re-infection at a minimum one-year follow-up. The results were compared to those achieved at similar follow-up in 10 patients treated with a static cement spacer. Demographic profile as measured by age and gender, and pre-operative Knee Society scores and range of motion were similar between the two groups.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVIII | Pages 44 - 44
1 Sep 2012
Kosashvili Y Lakstein D Studler U Ben-lulu O Safir O Gross AE Backstein D
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Purpose

The literature indicates that the tibial component in total knee arthroplasty (TKA) should be placed in internal rotation not exceeding 18 to the line connecting the geometrical center of the proximal tibia and the middle of the tibial tuberosity. These landmarks may not be easily identifiable intraoperatively. Moreover, an angle of 18 is difficult to measure with the naked eye.

Method

The angle at the intersection of lines from the middle of the tibial tuberosity and from its medial border to the tibial geometric center was measured in 50 patients with normal tibia. The geometric center was determined on an axial CT slice at 10mm below the lateral tibial plateau and transposed to a slice at the level of the most prominent part of the tibial tuberosity.

Similar measurements were performed in 25 patients after TKA in order to simulate the intra operative appearance of the tibia after making its proximal resection.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVIII | Pages 112 - 112
1 Sep 2012
Ben-Lulu OY Aderinto JB Backstein D Gross AE
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Purpose

The purpose of this study was to determine the functional outcome, imaging and complications of conversion of hip fusion to uncemented total hip replacement.

Method

The study group comprised eighteen patients who had undergone conversion of unilateral hip fusion to total hip replacement between 1996 and 2007. There were five men and 13 women. The diagnosis prior to fusion was traumatic injury in eight patients, developmental dysplasia in three patients, and septic arthritis in seven patients. Four of the patient who had septic arthritis in childhood had spontaneous hips fusion while the other underwent surgical arthrodesis.

The mean age at the time of conversion was 53 years (range, 21–77) and the mean time between fusion and conversion to hip replacement was 33 years (range, 11–60). Mean follow up was five years (range 2–15 years).

Data was collected by retrospective review of a prospective database. Uncemented acetabular components were used in all cases and uncemented femoral components were used in all but two patients. In three patients with abductor and soft tissue deficiency an intraoperative decision was made to use a constrained acetabular liner.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVIII | Pages 113 - 113
1 Sep 2012
Greidanus NV Garbuz DS Masri BA Duncan CP Gross AE Tanzer M Aziz A Anis A
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Purpose

The purpose of this study was to compare and evaluate the cost-effectiveness of the MIS Anterolateral Approach to that of the MIS Posterolateral and MIS Direct Lateral Approach.

Method

A prospective randomized control trial was designed and conducted to compare the MIS Anterolateral Approach to that of the MIS Posterolateral and MIS Direct Lateral Approach. Contemporary methods for economic evaluation were used to ascertain direct and indirect costs (in Canadian dollars) along with clinical effectiveness outcomes (SF6D and Pat5D utility measures). University and hospital ethics was obtained and patients were recruited and consented to participate in the RCT resulting in the assignment of 130 patients MIS hip arthroplasty procedures. Baseline patient demographics, comorbidity, quality of life, and utility were obtained for all patients. In-hospital costing data was obtained including operating room and patient room costs as well as medication, rehab and complications. Post-discharge costs were calculated from direct and indirect costs of medication, rehab, medical costs and complications until one year post-operatively. Clinical effectiveness measures were administered at intervals until one year post-operatively.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 559 - 559
1 Nov 2011
Backstein DJ Lakstein D Zarrabian M Kosashvili Y Kosashvili Y Safir O Gross AE
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Purpose: Component malrotation is a recognized cause of post total knee arthroplasty (TKA) pain. The objective of this study was to evaluate the functional outcomes of TKA revision for component malrotation, and to compare it to revision surgeries for aseptic loosening as a control comparison group.

Method: Twenty four patients who had TKA revision due to component malrotation as the only objective abnormality were reviewed. Only patients with preoperative computerized tomography (CT) documentation of 3° or more malrotation of at least one of the components were included. Mean combined rotation was 6.8° (range, − 12 − 3) excessive internal rotation. Twenty four matched control patients had TKA revision due to aseptic loosening.

Results: Mean follow up was 37 months (range, 24–65). Mean interval from index surgery was 41 months (range, 24–65) for the study group and 98 months (range, 11–222) for the control group (p=0.0003). Preoperative Knee Society Score (KSS) improved by 49 points (range, 16–80) at 6 months postoperatively for the malrotation patients and by 39 (range, − 7–78) for the loosening patients (p=0.08). At last follow-up, KSS was 80 (range, 60–89) for the malrotation group and 75 (range, 26–90) for the loosening group (p=0.14).

Conclusion: We recommend the use of CT scans in evaluation of all patients with early painful TKA’s and no objective evidence of infection. When component malrotation is demonstrated, we believe the results of this study validate consideration of early revision.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 586 - 586
1 Nov 2011
Zywiel MG Kosashvili Y Gross AE Safir O Lakstein D Backstein D
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Purpose: The literature regarding the outcome of total knee arthroplasty following distal femoral varus osteotomy is limited. The largest published series to date of eleven such patients suggested that medio-lateral constrained implants are commonly required as ligament balancing is difficult. This study presents mid-term outcomes of patients treated with total knee arthroplasty following distal femoral varus osteotomy at a single center.

Method: Twenty-two consecutive distal femoral varus osteotomies (21 patients) converted to total knee arthroplasties were reviewed at a mean follow-up of five years (range, two to 14 years). The mean duration between osteotomy and conversion to arthroplasty was 12 years (range, three to 21 years). In 14 patients (15 knees) the underlying etiology for the femoral osteotomy was primary knee osteoarthritis with valgus deformity, while in seven patients the procedure was performed to unload a fresh osteochondral allograft of either the lateral tibia (five patients) or femur (two patients). It is the authors’ routine to use posterior stabilized implants were used in all total knee arthroplasty surgeries. Femoral stems were used in six knees in which the bone quality was clinically determined by the surgeon to be sufficiently deficient to predispose to periprosthetic fractures, while the remaining sixteen knees were treated with unstemmed components. Modified knee society scores were used to evaluate the clinical outcomes preoperatively and at most recent follow-up.

Results: The mean knee society knee and function scores in surviving knees improved from 50 points (range, 10 to 75 points) and 50 points (range, 30 to 70 points) pre-operatively, to 91 points (range, 67 to 100 points) and 64 points (range, 50 to 70 points) at final follow-up, respectively. The mean arc of motion improved from 94 degrees (range, 70 to 115 degrees) to 114 degrees (range, 90 to 130 degrees). Two patients underwent revision arthroplasty for polyethylene wear and component loosening at eight and 11 years following the index arthroplasty, respectively. There were no fractures, infections or wound complications.

Conclusion: Total knee arthroplasty following distal femoral varus osteotomy reliably decreases pain and improves knee function. Standard posterior stabilized components provide satisfactory stability after appropriate ligamentous balancing, without the need for stemmed or highly constrained components in the majority of patients.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 262 - 262
1 Jul 2011
Backstein D Peskun C Mayne I Malempati H Kosashvili Y Sennik V Gross AE
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Purpose: Single anesthetic bilateral total knee arthroplasty (SABTKA) is a controversial procedure with a questionable safety profile. The purpose of this study was to determine if specific, individual preoperative medical co-morbidities can predict perioperative complications in patients undergoing SABTKA.

Method: The records of all SABTKA performed between 1997 and 2007 at 1 large community hospital and 1 academic, university hospital were retrospectively reviewed. Complete demographic data, preoperative co-morbidities (cardiovascular disease, COPD, diabetes, and hypertension), and perioperative complications for 156 patients were collected and analyzed using logistic multivariate regression analysis. Comparison was made to an age, gender, and co-morbidity matched cohort of patients treated with unilateral TKA.

Results: In the SABTKA group only 11% of patients had a preoperative history of cardiovascular disease yet 89% of all post operative myocardial infarctions (MI) occurred in this population (p< 0.001, Odds Ratio 57.8). Cardiovascular disease also predicted need for admission to ICU (p< 0.001, Odds Ratio 50.8), and number of days spent in the ICU (p< 0.001). In those patients without preoperative cardiovascular disease or COPD the rate of MI was only 0.64%. All differences were significant when compared to the matched unilateral TKA cohort. Age, gender, diabetes, and hypertension did not predict perioperative complications in the SABTKA cohort.

Conclusion: The literature indicates there are certain populations of patients at higher risk for perioperative complications after SABTKA. This study clearly identifies a subpopulation of patients that have cardiovascular disease and are at an unacceptably high risk of perioperative MI. Cardiovascular disease should likely be considered an absolute contraindication to SABTKA.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 275 - 275
1 Jul 2011
Backstein D Lakstein D Safir O Kosashvili Y Gross AE
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Purpose: Acetabular component revision in the context of large, contained bone defects with less than 50% host-bone-contact traditionally required roof reinforcement or antiprotrusio cages. Trabecular Metal (TM) cups (Zimmer, Warsaw, Indiana) may offer a viable treatment alternative. The objective of this study was to evaluate the clinical and radiological outcome of this mode of treatment.

Method: Fifty-four hip revision acetabular arthroplasty procedures performed with TM cups for contained defects offering ≤50% contact with native bone were prospectively followed. Average follow-up was 45 months (range 24–71). All patients were clinically and radiographically evaluated for evidence of loosening or failure.

Results: Contact with bleeding host bone ranged from 0 to 50% (average 23%). At latest follow up 43 (79.6%) arthroplasties had excellent or good results, 8 (14.8%) cases had medium or fair results and 3 cases (5.6%) had poor results. Two cups failed and had to be revised. Two additional cups had radiological evidence of probable loosening. Overall preliminary survivorship of the revision acetabulae was 96%. Complications included 4 dislocations and 1 sciatic nerve palsy.

Conclusion: Treatment of cavitary defects with less than 50% host-bone contact with using TM cups, without structural support by augments or structural bone grafts, is a viable option.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 275 - 275
1 Jul 2011
Backstein D Kosashvili Y Safir O Lakstein D MacDonald M Gross AE
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Purpose: Pelvic discontinuity associated with bone loss is a complex challenge in acetabular revision surgery. Reconstruction with anti protrusion cages, Trabecular Metal (Zimmer, Warsaw, Indiana) cups and morselized bone (Cup-Cage) constructs is a relatively new technique used by the authors for the past 6 years. The purpose of the study was to examine the clinical outcome of these patients.

Method: Thirty-two consecutive acetabular revision reconstructions in 30 patients with pelvic discontinuity and bone loss treated by cup cage technique between January 2003 and September 2007 were reviewed. Average clinical and radiological follow up was 38.5 ± 19 months (range 12 – 68, median 34.5). Failure was defined as component migration > 5mm.

Results: In 29 (90.6%) patients there was no clinical or radiographic evidence indicative of loosening at latest follow up. Harris Hip Scores improved significantly (p< 0.001) from 46.6 ± 10.4 to 78.7 ± 10.4 at 2 year follow up. In 3 patients the construct migrated at 1 year post surgery. One construct was revised to anti protrusion cage with a structural graft while the other was revised to a large Trabecular Metal cup. The third patient is scheduled for revision. Complications included 2 dislocations, 1 infection and 1 partial peroneal nerve palsy. Two patients died due to unrelated reasons at 1 and 3 years post surgery, respectively.

Conclusion: Treatment of pelvic discontinuity by Cup-Cage construct is a reliable option based on preliminary results which suggest restoration of the pelvic mechanical stability. However, patients should be followed closely in order to detect cup migration until satisfactory bony ingrowth into the cup takes place.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 22 - 22
1 Mar 2010
Kim W Backstein D Heras FL Safir O Pritzker KPH Gross AE
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Purpose: Fresh osteochondral allograft (FOCA) transplantation has been an effective treatment option with promising long-term clinical outcomes for focal post-traumatic or intra-articular lesions in the knee for young, active individuals. The goal of this study was to assess the osteochondral allograft to characterize the histopathologic features of early and late graft failure, as well as prolonged graft survival.

Method: We examined histological features of thirtyfive fresh osteochondral allograft specimens retrieved at the time of subsequent graft revision, osteotomies or total knee arthroplasty.

Results: The graft survival time in our samples ranged from one to twenty-five years based on their time to reoperation. Histological features of early graft failures were lack of chondrocyte viability, loss of matrix cationic staining, and features of mechanical instability. Histological features of late graft failures were fracture through the graft, active and incomplete remodelling of the graft bone by the host bone, and resorption of the graft tissue by synovial inflammatory activity at graft edges. Histological features associated with long-term allograft survival included viable chondrocytes, functional preservation of matrix, and complete replacement of the graft bone with the host bone. These long-term histological findings correlate clinically with excellent Oxford Knee Scores (mean 17.5) in age-matched cohorts with allograft transplants surviving 20 (mean 20.9) years or longer.

Conclusion: Given chondrocyte viability, long-term allograft survival depends on graft stability by rigid fixation of host bone to graft bone. With the stable osseous graft base, the hyaline cartilage portion of the allograft can survive and function for 25 years or more.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 230 - 230
1 May 2009
Lim G Backstein D Boscainos P Gross AE Safir O
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The purpose of this study was to ascertain the radiographic results of the modified extended trochanteric sliding osteotomy (ETSO), performed by the senior author. The main feature of the ETSO is preservation of the posterior 1cm of greater trochanter and its attached external rotators. Results with this particular osteotomy for revision hip arthroplasty have not been previously reported.

We reviewed forty-eight ETSOs in forty-six patients that underwent revision hip arthroplasty from March 2000 to March 2006. Nineteen osteotomies were for femoral revision alone, and twenty-nine osteotomies were performed for femoral and acetabular revision. All but six (12.5%) had cortical strut augmentation of the osteotomy. The length of the osteotomy, the length of distal fit, the number of wires used were recorded and their relation to union of the osteotomy and femoral stem loosening were investigated.

The rate of ETSO union in this study was 91.3%. Four osteotomies were not united and this was associated with femoral stem subsidence and loosening requiring femoral stem revision in three cases. The rate of femoral stem loosening requiring revision was 8.3%. The length of the osteotomy did not correlate with femoral stem loosening, but a distal fit of less than 9cm was highly significant(p=0.001) with regards to loosening. The use of cortical struts was not protective against osteotomy non-union or femoral stem loosening. Osteotomy union was shown to be dependant on a well fixed (p< 0.0001) and stable stem (p< 0.0001). Three patients dislocated postoperatively (6.5%), and only one of these required revision surgery.

The modified extended trochanteric osteotomy has a low rate of dislocation and a reliable rate of union. We have shown that a well fixed and stable stem is critical to successfully obtaining union of the osteotomy.