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Bone & Joint Open
Vol. 4, Issue 12 | Pages 970 - 979
19 Dec 2023
Kontoghiorghe C Morgan C Eastwood D McNally S

Aims

The number of females within the speciality of trauma and orthopaedics (T&O) is increasing. The aim of this study was to identify: 1) current attitudes and behaviours of UK female T&O surgeons towards pregnancy; 2) any barriers faced towards pregnancy with a career in T&O surgery; and 3) areas for improvement.

Methods

This is a cross-sectional study using an anonymous 13-section web-based survey distributed to female-identifying T&O trainees, speciality and associate specialist surgeons (SASs) and locally employed doctors (LEDs), fellows, and consultants in the UK. Demographic data was collected as well as closed and open questions with adaptive answering relating to attitudes towards childbearing and experiences of fertility and complications associated with pregnancy. A descriptive data analysis was carried out.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_6 | Pages 8 - 8
1 May 2021
Tolk J Eastwood D Hashemi-Nejad A
Full Access

Introduction

Legg-Calvé-Perthes disease (LCPD) often results in femoral head deformity and leg length discrepancy (LLD). Objective of this study was to analyse femoral morphology in LCPD patients at skeletal maturity to assess where the LLD originates, and evaluate the effect of contralateral epiphysiodesis for length equalisation on proximal and subtrochanteric femoral lengths.

Materials and Methods

All patients treated for LCPD in our institution between January 2013 and June 2020 were retrospectively reviewed. Patients with unilateral LCPD, LLD of ≥5mm and long leg standing radiographs at skeletal maturity were included. Total leg length, femoral and tibial length, articulotrochanteric distance (ATD) and subtrochanteric femoral length were compared between LCPD side and unaffected side. Furthermore, we compared leg length measurements between patients who did and who did not have a contralateral epiphysiodesis.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_6 | Pages 52 - 52
1 May 2021
Merchant R Tolk J Ayub A Hashemi-Nejad A Eastwood D Tennant S Calder P Wright J Khan T
Full Access

Introduction

Leg length discrepancy (LLD) in patients with unilateral developmental dysplasia of the hip (DDH) can be problematic for both patients and surgeons. Patients can acquire gait asymmetry, back pain, and arthritis. Surgical considerations include timing of correction and arthroplasty planning. This study audits standing long leg films performed at skeletal maturity in our patients. The aim of this study is to identify if surgical procedure or AVN type could predict the odds of needing an LLD Intervention (LLDI) and influence our surveillance.

Materials and Methods

Hospital database was searched for all patients diagnosed with DDH. Inclusion criteria were patients with appropriately performed long leg films at skeletal maturity. Exclusion criteria were patients with non DDH pathology, skeletally immature and inadequate radiographs. All data was tabulated in excel and SPSS was used for analysis. Traumacad was used for measurements and AVN and radiologic outcome grades were independently classified in duplicate.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_11 | Pages 7 - 7
1 Jun 2017
Calder P Shaw S Roberts A Tennant S Sedki I Hanspal R Eastwood D
Full Access

Purpose

This study compares outcomes in patients with complete congenital fibula absence, associated with severe lower limb deformity, treated with an amputation protocol to those using an extension prosthesis.

Method

32 patients were identified. 9 patients (2M: 7F, median age at presentation of 22 yrs) utilized an extension prosthesis. 23 patients (16M: 7F, median age at presentation of 10 months) underwent 25 amputations during childhood: only two underwent tibial kyphus correction to facilitate prosthetic wear.

Mobility was assessed using the SIGAM and K scores. Quality of life was assessed using the PedsQL inventory questionnaire; pain by a verbal severity score. Patients undergoing amputation were further subdivided by age, below and above 2 yrs at the time of surgery.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_13 | Pages 8 - 8
1 Jun 2017
Calder P Shaw S Roberts A Tennant S Sedki I Hanspal R Eastwood D
Full Access

Purpose

This study compares outcomes in patients with complete congenital fibula absence treated with an amputation protocol to those using an extension prosthesis.

Introduction

Complete fibula absence presents with significant lower limb deformity. Parental counselling regarding management is paramount in achieving the optimum functional outcome. Amputation offers a single surgical event with minimal complications and potential excellent functional outcome.


Bone & Joint 360
Vol. 6, Issue 1 | Pages 3 - 6
1 Feb 2017
Horn A Eastwood D


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_15 | Pages 6 - 6
1 Sep 2016
Horn A Wright J Eastwood D
Full Access

This study aims to evaluate the development of deformity in patients with hypophosphataemic rickets and the evolution of the orthopaedic management thereof.

Fifty-four patients had undergone treatment for hypophosphataemic rickets at our institution since 1995. Clinical records for all patients were obtained. Forty-one patients had long leg radiographs available that were analysed using Traumacad™ software. Statistical analysis was performed using SPSS 23 (SPSS Inc., Chicago, Illinois, USA).

Of the 41 patients, 18 (43%) had no radiographic deformity. 20 have undergone bilateral lower limb surgery for persistent deformity (Mechanical Axis ≥ Zone 2). A further 3 patients are awaiting surgery. Six patients (12 limbs, 14 segments) had osteotomies and internal fixation as primary intervention: only one limb developed recurrent deformity. There were no major complications.

Fourteen patients (28 limbs) had 8-plates (Orthofix, Verona) applied. In 5 limbs correction is on-going. Neutral alignment (central Zone 1) was achieved in 14/20 (70%) patients. Two patients required osteotomy and external fixation for resistant deformity. The mean rate of angular correction following 8-plate application was 0.3 and 0.7 degrees/month for the tibia and femur respectively. The mean age at 8-plate insertion was 10.25y (5–15y). Patients with more than 3 years of growth remaining responded significantly better than older patients (Fisher Exact Test, p=0.024). Guided growth was more successful in correcting valgus deformity than varus deformity (Fisher Exact Test, p=0.04). In the younger patients, diaphyseal deformity corrected as the mechanical axis improved at the rate of 0.2 and 0.7 degrees /month for the tibial and femoral shafts. Serum phosphate and alkaline phosphatase levels did not affect response to surgery or complication rate.

Guided growth by means of 8-plates is a successful in addressing deformity in hypophosphataemic rickets. Surgery is best performed in patients with more than 3 years of growth remaining.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_11 | Pages 5 - 5
1 Jun 2016
Wilkinson J Hatzikotoulas K Clark M Shah K Eastwood D Zeggini E
Full Access

Introduction

Although DDH is one of the most common skeletal dysplasias (incidence 1.5 cases per 1000 births), it remains slow and costly to recruit large-scale patient cohorts for powerful genetic association studies. In this work we have successfully used the NJR as a platform to generate a DDH biobank of 907 individuals, upon which we have conducted the first ever genome-wide association study (GWAS) for DDH.

Methods

5411 patients recorded as having a hip replacement for ‘hip dysplasia’ between March 2003 and December 2013 were approached to participate in the study. Following filtering by questionnaire for non-DDH cases and non-European Caucasians, 907 patients returned a completed saliva sample. A randomly selected sample of individuals participating on the UK Household Longitudinal Study that had been previously genotyped using the same platform were used as controls at a case:control ratio of 1:4. A further data set consisting of 332 cases, 1375 controls and 26 variants was used to replicate the top signals.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_9 | Pages 9 - 9
1 Aug 2015
Yeo A Richards C Eastwood D
Full Access

This study aimed to define the rates of lower limb angular correction using temporary hemiepiphysiodesis in differing skeletal pathologies.

A retrospective review of 61 children (36M:25F) with angular deformities about the knee who underwent 8-plate hemiepiphysiodesis (mean age 10.8y) was undertaken. The children were divided into 9 groups based on their underlying pathology (lower limb hypoplasia, Blount's disease, skeletal dysplasia, rickets, metabolic disease, acquired growth disturbance, vascular malformation, steroid use and complex genetic disorders). Radiographic measurements of each limb segment was undertaken using the TraumaCad® digital templating software based on standing long-leg radiographs - mechanical lateral distal femoral angle (mLDFA) and mechanical medial proximal tibial angle (mMPTA). The rate of correction of each parameter was calculated as a function of the time lapse between the operation date and first radiographic evidence of full correction of the mechanical axis (zone 1).

A total of 144 limb segments (80 distal femoral, 64 proximal tibial physes) were analysed. 62.5% of children had mechanical axes outside the knee joint at the time of operation; 63.2% achieved full correction. The rate of angular correction at the distal femur (mLDFA) was quickest in those with acquired growth disturbance (1.15°/month), complex genetic disorders (1.12°/month) and rickets (0.93°/month). It was slowest in those with vascular malformation (0.40°/month), lower extremity hypoplasia (0.44°/month) and metabolic disease (0.49°/month). At the proximal tibia, mMPTA correction was quickest in those with acquired growth disturbance (0.77°/month) and skeletal dysplasia (0.57°/month); whilst being slowest in those with metabolic disease (0.22°/month) and Blount's disease (0.29°/month).

The rate of angular correction about the knee varies with the underlying pathology with correction rates varying up to 3-fold. This study demonstrated the differential rate of correction of angular deformities in children with different skeletal pathologies, which would help guide the timing of hemiepiphysiodesis.


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_1 | Pages 9 - 9
1 Jan 2014
Jayakumar P Hartmann C Eastwood D
Full Access

Aim

To review the natural history of upper limb osteochondromas and assess their functional effect.

Materials

We performed a retrospective casenote review of a consecutive patient cohort presenting between 1997–2012 with upper limb osteochondromas. Indications for surgical intervention were noted and considered to be cosmetic, functional (including pain relief) and ‘prophylactic’ in terms of deformity prevention. All patients were invited to complete questionnaires for the PODCI, DASH, OSS and MHS scores.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_23 | Pages 1 - 1
1 May 2013
Welck MJ Calder P Eastwood D
Full Access

Purpose of Study

To see if the addition of a locking plate to FD rod fixation of osteogenesis imperfecta confers extra strength and allows earlier mobilisation.

Introduction

Osteogenesis imperfecta is a heterogeneous group of disorders with congenital osseous fragility. The goal of surgery is to minimise the incidence of fracture and correct deformity. The concept of multilevel osteotomies and intramedullary fixation with a non-extendable nail was popularised by Sofield and Millar in 1959. The Bailey Dubow telescoping nail was introduced in 1963. The Fassier-Duval (FD) telescoping nail is a more recent design inserted via smaller incisions, in conjunction with percutaneous osteotomies. However there are still problems. Often the medullary canal may be too narrow to harbour a nail of adequate size for the body. Furthermore they do not give significant rotational control, which is compounded by the elasticity of the soft tissues.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_6 | Pages 11 - 11
1 Feb 2013
Scally M Van't Hoff W Bockenhauer D Eastwood D
Full Access

Aim

To assess the efficacy of combined medical and surgical management in obtaining normal lower limb mechanical alignment in a patient cohort with genotypically similar hypophosphataemic rickets.

Methods

A notes and radiograph audit was performed of all patients attending our institution with hypophosphataemic rickets: a subset with PHEX gene anomalies was studied further. Lower limb radiographs were assessed at two points during childhood and note made of treatment start, compliance; indication, timing and result of surgery. Standing leg alignment radiographs were measured at skeletal maturity or at latest review.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_6 | Pages 17 - 17
1 Feb 2013
Stöhr K Randhawa S Calder P Tennant S Hashemi-Nejad A Eastwood D
Full Access

Purpose of study

We hypothesised that Vitamin D deficiency could be related to SUFE in children without endocrinological abnormalities. We therefore sought to examine prevalence and severity of Vitamin D insufficiency in a cross-section of SUFE patients.

Methods

Vitamin D levels were tested for at time of hospital admission for operative treatment of SUFE. Seven patients, between the months of July 2011 to November 2011, presented to our institution. All were chronic, stable slips treated with in-situ screw fixation. All patients presented in the summer months and were operated on within 3 weeks of presentation.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 45 - 45
1 Sep 2012
Bajaj S Patel S Eastwood D Calder P
Full Access

Aim

To evaluate the results and complications of bone transport in the treatment of massive tibial bone defects, using the Ilizarov method.

Methods

15 patients underwent bone transport using the Ilizarov technique to treat massive tibial bone defects. The average age of the patients was 8.7 years (3–24 years) and the mean bone defect was 10.8 cms. Following a latent period of 1 week, distraction of the transport doughnut was commenced at 1mm/24 hours in 4 quarterly turns. A docking procedure was performed in 7 cases which involved freshening of the bone ends and autogenous bone grafting from the iliac crest. Following docking the fixator was removed once the regenerate had consolidated.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIV | Pages 11 - 11
1 May 2012
Siddiqui N Malaga-Shaw O Eastwood D
Full Access

Purpose

To define the orthopaedic problems associated with pseudoachondroplasia (PSACH) and their functional impact.

Methods

We reviewed the medical records of 12 consecutive patients presenting to our unit. Radiographic analysis of deformity included assessment of mechanical axis and dysplasia at hip, knee and ankle measured by acetabular index (AI), Reimer's migration percentage (MP), neck-shaft angle, distal lateral femoral (aDFLA) and proximal (mMPTA) and distal tibial angles.

The paediatric/adolescent PODCI questionnaires and the SF36 were used to assess quality of life issues.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIV | Pages 4 - 4
1 May 2012
de Gheldere A Hashemi-Nejad A Calder P Tennant S Eastwood D
Full Access

Purpose

To document the success rate of closed reduction and soft tissue release in the treatment of bilateral true dislocation in developmental dysplasia of the hip (DDH).

Methods

Case-note review of 22 children (44 hips) with idiopathic bilateral hip dislocation referred to a tertiary centre before walking age. The management protocol was as follows:

Examination under general anaesthesia, arthrogram, closed reduction and appropriate soft tissue release (adductors/psoas), application of a ‘frog’ cast.

CT scan at 2 weeks to confirm reduction.

Change of cast and arthrogram at 6 weeks to confirm improving position and stability.

Cast removal at 12 weeks, and application of an abduction brace for 6 weeks.

Treatment failure could occur on day 1 (failure of reduction), at week 2 (failure to maintain reduction), at week 6, or after cast removal.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_VI | Pages 8 - 8
1 Mar 2012
Laborie L Lehmann T Engesßter I Eastwood D Engesßter L Rosendahl K
Full Access

Purpose

To determine whether radiographically demonstrated femoral neck irregularities (pistolgrip-deformity, focal prominences or lytic defects) are associated with positive clinical impingement tests.

Methods

The 1989 Bergen birth cohort (n=4004) was invited to a population-based follow-up including clinical examination and two pelvic radiographs. 2081 (52%) were enrolled. Associations between clinical and radiographic findings were examined using chi-squared or Fischer's exact test.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_VII | Pages 7 - 7
1 Mar 2012
Calder P Tennant S Hashemi-Nejad A Catterall A Eastwood D
Full Access

Purpose

To investigate the effect of soft tissue release (STR) and the length of postoperative immobilisation on the long term outcomes of closed reduction (CR) of the hip for developmental dysplasia of the hip.

Materials

77 hips (72 patients) who had undergone closed reduction (CR) between 1977-2005 were studied retrospectively to review their outcome (Severin grade), identify the reasons for failure and to assess factors associated with residual dysplasia. Particular attention was paid to the use of a STR at the time of CR (to improve initial hip stability) and the duration of postoperative immobilisation.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_VII | Pages 10 - 10
1 Mar 2012
de Gheldere A Calder P Bradish C Eastwood D
Full Access

Purpose

To document the incidence and nature of complications associated with hemiepiphysiodesis using a screw and plate device (8-plate, Orthofix).

Methods

We reviewed case notes and radiographs of 71 children (130 segments) with lower limb deformities treated with temporary hemiepiphyseal arrest using the 8-plate. 96% of deformities were in the coronal plane, 4% sagittal. 72% of coronal deformities demonstrated valgus malalignment. We defined three types of complications:

early (perioperative) complications eg infection and/or wound breakdown, bleeding, neurological impairment

implant related complications such as soft tissue irritation, plate breakage or migration,

complications involving the growth plate including rebound deformity, early physeal closure or iatrogenic deformity.

Complications were related to variables of patient age, gender, diagnosis, location of deformity and associated surgery.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 190 - 190
1 May 2011
Dhawan R Hashemi-Nejad A Eastwood D
Full Access

Introduction: Avascular necrosis (AVN) is a serious complication affecting the femoral head following an unstable slipped capital femoral epiphysis (SCFE) particularly if the slip is severe. The incidence of AVN may be as high as 47%.

Purpose: To determine whether or not the avascular insult associated with a massive unstable SCFE is a temporary event and whether this may resolve in the second week post injury.

Methods: 6 patients (4 male:2 females), mean age 14.9 yrs (13.2–17.5yrs) with acute severe unstable SCFE were reviewed. The mean Southwick slip angle was 51.20 deg (40.1 – 66.60). 5 of 6 cases were severe. All cases underwent a subcapital cuneiform femoral neck osteotomy at a mean 14 days (7–24 days) after the acute event. Pre-operatively, the hip/limb was rested in ‘slings and springs’. No hip underwent a manipulative procedure. All hips underwent an MRI scan at a mean 8.6 days post injury (range 4–15 days) to determine the viability of the femoral head.

Results: In all 6 cases, the femoral head was reported to be viable. All femoral heads showed signs of bone oedema and other features indicative of a blood supply.

Following the cuneiform osteotomy, patients were mobilized partial weight bearing for 8 weeks. At a mean 12 month follow up, radiographs confirmed that all oste-otomies had united and no hip showed evidence of AVN.

Conclusion: If the acute severe unstable slip is associated with an avascular insult to the femoral head, this may be a temporary phenomenon and assuming the hip is not subjected to any immediate secondary trauma such as operative reduction, then there may be a spontaneous recovery in the blood supply as evidenced by the viable femoral head seen on MRI.

Significance: Our study suggests that there may be a time period during which the slipped femoral head may be vulnerable to a second insult and hence AVN. The timing of any surgical intervention designed at reducing the slip should take this into account and be performed carefully to ensure that the blood vessels on the posterior aspect of the femoral neck are not disrupted. When the presentation of an acute unstable and severe SCFE is delayed beyond 24 hours, we favour delaying subsequent operative correction for a further 2–3 weeks to maximize the chance of a viable femoral head.