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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 21 - 21
1 Mar 2012
Alvi F Williamson J Dashti H Mohammad S Ross E Oxborrow N
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Introduction

Many journals require outcome data at 2 years post-operative for the assessment of operative procedures in spinal surgery. This study seeks to clarify the timescale of improvement after surgery to see if a shorter period of assessment will indicate the final outcome.

Methods

Outcome data for 185 consecutive patients who underwent spinal surgery was analysed. All were given a global outcome assessment questionnaire (as used in the Swedish Spinal Fusion study) at 6 months, 1 year and 2 years following surgery. Results were analysed according to the type of spinal surgery undertaken.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 98 - 98
1 Feb 2012
Ross R Harris J Oxborrow N Patwardin A Dashti H
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Purpose of the study

In a recent study, O'Leary et al. [2005] reported their observations on the patterns of Charité disc prosthesis motion under physiologic loads. The purpose of this study was to investigate whether the motion patterns observed in the in vitro model are replicated in clinical practice.

Methods

55 patients with implanted SB Charité 111 artificial lumbar discs were subjected to flexion extension x-rays. Two consultant spinal surgeons and a neuro-radiological consultant were asked to classify the pattern of motion in the clinical subjects based on the patterns observed in the in vitro model. The results were recorded independently then collated. Following this first round of observations an algorithm was devised and the method of measurement was standardised.

Summary of findings: There was modest correlation amongst the three observers in distinguishing motion from nonmotion (Kappa 5.6). There was less agreement on what type of motion was present. On both counts using the algorithm there was no correlation. The clinical study based on patients' flexion-extension radiographs identified the following patterns of prosthesis motion:

angular motion between both the upper and lower endplates and core, with visual evidence of core motion;

angular motion predominantly between the upper endplate and core, with little visual evidence of core motion;

lift-off of upper prosthesis endplate from core or of core from lower endplate;

core entrapment and deformation; and

no motion. There are difficulties associated with the interprtation of these using only flexion extension views.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 495 - 495
1 Sep 2009
McLorinan G Younis F Dashti H Oxborrow N Williamson J
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Background: Prader-Willi syndrome is associated with multiple musculoskeletal manifestations including scoliosis, joint laxity, hip dyplasia and lower limb deformity. Scoliosis is reported in almost half of patients with Prader-Willi; however, only a small proportion ever have surgery. The literature suggests that surgery in this group of patients is often difficult. Obesity and apnea cause anaesthetic concern. The surgical procedure is reported as being complicated by excessive intra-operative blood loss, and difficulty with instrumentation; possibly as a result of osteopenia, is described.

Purpose: To compare the experience of scoliosis surgery in Prader-Willi patients in our institution with that previously reported in the literature.

Methods: The notes and x-rays of 6 patients with Prader-Willi syndrome who had corrective scoliosis were reviewed.

Results: Six patients (4 female and 2male) underwent corrective scoliosis surgery. The mean age at which scoliosis was detected in the patients was 5 years (range 2–7years). The mean Cobb angle at time of initial referral was 30° (range 8°–86°). Indication for surgery in all cases was curve progression. The mean age at time of surgery was 11.8 years (range 10–13years). The mean pre-operative Cobb angle was 70° (range 40°–90°) and mean post-operative Cobb angle was 23° (range 10°–40°). Three patients had posterior surgery with instrumentation, one had anterior instrumentation only and two patients had combined anterior release with posterior instrumentation. The most proximal instrumentation levels ranged from T2–T6 and the most distal instrumentation levels ranged from T11-L5. Three patients had all pedicle screw fixation, 2 had hybrid fixation (with screws at curve apex) and one had anterior all screw fixation. The mean operative time was 335 mins (range 190–540 mins) and the mean blood loss was 29% of total blood volume (range 14–55%). Standard anaesthetic technique was used in each case and all patients were extubated immediately after surgery. Patients were discharged on average 8 days post surgery (range 6–14 days). One patient had a wound infection and a stitch granuloma requiring surgical debridement and one patient required trimming of proximal end of rod because it was prominent.

Conclusion: Scoliosis surgery in patients with Prader-Willi offers adequate deformity correction and in our experience is not associated with operative technical difficulty, major complications or a prolonged hospital stay.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 107 - 107
1 Mar 2009
Fawzy E Dashti H Oxborrow N Williamson J
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Aim: To measure the quality of five major scientific meetings by assessing the publication rate of papers presented and recording their citation index.

Material and Methods: Abstracts of podium presentations at the meetings of the Scoliosis Research Society, International Society for the Study of the Lumbar Spine, British Scoliosis Society, BritSpine and Eurospine were included. We performed a Medline search to identify publications from the abstract. We calculated the time from meeting to publication and recorded the citation rate of the articles.

Results: Of 396 abstracts, 182 were published in peer-review journals – a publication rate of 46%. The publication rates of the five meetings (SRS, BSS, ISSLS, Eurospine, Britspine) were 69%, 53%, 51%, 38%, 24% respectively. Most publications were in “Spine” (55%), then European Spine Journal (11%). The median citation rate of the papers from the SRS, ISSLS, BSS, Eurospine, Britspine meetings was 3, 3, 3, 2, and 1 respectively. The average time to publication was 16 months.

Discussion & Conclusions: Podium presentation is a valuable means for the dissemination of research findings. However, a paper in a peer-reviewed journal is subjected to greater scrutiny, and is perhaps a better indicator of the work’s merit. The average rate of publication in medicine following presentation is 45%1. Spinal meetings are within this range. Although the quality of the scientific work is not the only factor to determine publication, and nor is the quality of the presentations the only factor to assess in evaluating a meeting, the rate of publication and citation rate provide an indicator of the quality and scientific level of meetings.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 458 - 458
1 Aug 2008
Fawzy E Dashti H Oxborrow N Williamson J
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Aim: To measure the quality of five major scientific meetings by assessing the publication rate of papers presented and recording their citation index.

Material and Methods: Abstracts of podium presentations at the meetings of the Scoliosis Research Society, International Society for the Study of the Lumbar Spine, British Scoliosis Society, BritSpine and Eurospine were included. We performed a Medline search to identify publications from the abstract. We calculated the time from meeting to publication and recorded the citation rate of the articles.

Results: Of 396 abstracts, 182 were published in peer-review journals – a publication rate of 46%. The publication rates of the five meetings (SRS, BSS, ISSLS, Eurospine, Britspine) were 69%, 53%, 51%, 38%, 24% respectively. Most publications were in “Spine” (55%), then European Spine Journal (11%). The median citation rate of the papers from the SRS, ISSLS, BSS, Eurospine, Britspine meetings was 3, 3, 3, 2, and 1 respectively. The average time to publication was 16 months.

Discussion & Conclusions: Podium presentation is a valuable means for the dissemination of research findings. However, a paper in a peer-reviewed journal is subjected to greater scrutiny, and is perhaps a better indicator of the work’s merit.

The average rate of publication in medicine following presentation is 45%1. Spinal meetings are within this range.

Although the quality of the scientific work is not the only factor to determine publication, and nor is the quality of the presentations the only factor to assess in evaluating a meeting, the rate of publication and citation rate provide an indicator of the quality and scientific level of meetings.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 449 - 449
1 Aug 2008
Verma R Dashti H Patel D Oxborrow N Williamson J
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There is an increasing awareness of the need to avoid of homologous blood transfusion in elective surgical practice. This stems from a better appreciation of the adverse effects of homologous blood transfusion and increasing pressure on blood stocks because of increasing restrictions on potential donors.

This study examines the effect of using modern blood conservation methods on the subgroup of our patients having surgery for adolescent idiopathic scoliosis. We chose this group because it is a homogenous group of patients of similar age, all of whom had major surgery of a similar severity, and in whom there were few contraindications to our blood conserving strategies.

We studied 78 consecutive patients with adolescent idiopathic scoliosis who underwent surgery. They were divided into two groups. Patients in the study group had one or more modern blood conservation measures used perioperatively. The patients in the comparison group did not have these measures.

There were 46 patients in the study group and 32 in the comparison group. Eight patients who had anterior only surgery, were excluded. The two groups did not differ in age, body weight, and number of levels fused or the type of surgery.

Only 2 patients in the study group were transfused with homologous blood and even these transfusions were off protocol. Wastage of the autologous predonated units was minimal (6/83 units predonated). In contrast all patients in the comparison group were transfused homologous blood. There was significant decrease (p = 0.005) in the estimated blood loss when all the blood conservation methods were employed in the study group.

Using blood conservation measures, lowering the hemoglobin trigger for transfusion and education of the entire team involved in the care of the patient can prevent the need for homologous blood transfusion in patients undergoing surgery for adolescent idiopathic scoliosis.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 479 - 480
1 Aug 2008
Williamson JB Ross E Mohammad S Oxborrow N Dashti H Norris H
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Audit is an important part of surgical practice. Commissioners may use it as evidence of quality assurance. No comprehensive audit exists in spinal surgery. Usage of existing databases is disappointing. We developed an audit database which was comprehensive and gathered patient outcomes. The underlying principles were:

All patients having surgery should enter,

Duplicate data entry should be avoided

No effort should be required of the participating surgeons.

Demographic data, OPCS codes, length of stay and other data were downloaded directly from the hospital information systems. A monthly printout of patients enrolled was provided to the audit coordinator. She was responsible for the collection of clinical outcomes at 6 months, 12 months, and 2 years after surgery. The initial audit involved the Northwest and Mersey Regions. Data from the hospital information systems (HIS) for two years were available for comparison. Unfortunately only two centres gathered clinical outcomes. We have continued to gather data. 380 patients have been enrolled. HIS data are available for all. With varying lengths of follow up, there are 1045 potential clinical outcomes available. Only 8 patients (2%; 8 outcomes, 0.76%) have been lost to follow up. Using this data we are able to compare outcomes between surgeons, between surgical procedures, and see changes over time. As far as we know we are the only centre in the UK able to do this. It is a valuable Clinical Governance tool. We believe that the principles underlying this audit are the only means to obtain comprehensive outcome audit in surgery.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 212 - 212
1 Apr 2005
Gilbody J Dashti H Birch N Ross ERS
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Background and purposes of study The objective of this study is to report the preliminary clinical data from a stand-alone interbody fusion cage (Stabilis™) from two centres.

Methods and results This was a retrospective group comparative study. Anterior lumbar interbody fusion was performed using Brantigan (n=6) or Stabilis™ cages (n=19). Clinical assessment was performed using standardised questionnaires. Lumbar flexion/extension views were used to assess union and implant subsidence. There were no significant differences between the groups for ODI, VAZ, MZ and MSPQ pre-operatively. The Stabilis group showed an improvement in ODI (pre: 49.4; post: 39.3; p=0.024), VAS (pre: 76.1; post: 47.8; p< 0.01) and MZ (pre 32.9; post: 20.6; p< 0.01).

There was no statistical improvement in the Brantigan cage group. Despite clinical improvement, five patients in the Stabilis group failed to unite and six demonstrated subsidence of the implant. The relationship between non-union and subsidence was statistically significant (p = 0.017). Furthermore, the change in ODI between patients who united and those who did not was both statistically significant (p=0.03) and the difference in mean ODI between the two groups was considerable (21%).

Conclusions: Stand-alone cages show promise, involve a shorter operating time and less tissue trauma for the patient. This study has identified a high rate of non-union and implant subsidence. This did not appear to be clinically relevant.