Artificial intelligence and machine-learning analytics have gained extensive popularity in recent years due to their clinically relevant applications. A wide range of proof-of-concept studies have demonstrated the ability of these analyses to personalize risk prediction, detect implant specifics from imaging, and monitor and assess patient movement and recovery. Though these applications are exciting and could potentially influence practice, it is imperative to understand when these analyses are indicated and where the data are derived from, prior to investing resources and confidence into the results and conclusions. In this article, we review the current benefits and potential limitations of machine-learning for the orthopaedic surgeon with a specific emphasis on data quality.

Aims. To evaluate how abnormal proximal femoral anatomy affects different femoral version measurements in young patients with hip pain. Methods. First, femoral version was measured in 50 hips of symptomatic consecutively selected patients with hip pain (mean age 20 years (SD 6), 60% (n = 25) females) on preoperative CT scans using different measurement methods: Lee et al, Reikerås et al, Tomczak et al, and Murphy et al. Neck-shaft angle (NSA) and α angle were measured on coronal and radial CT images. Second, CT scans from three patients with femoral retroversion, normal femoral version, and anteversion were used to create 3D femur models, which were manipulated to generate models with different NSAs and different cam lesions, resulting in eight models per patient. Femoral version measurements were repeated on manipulated femora. Results. Comparing the different measurement methods for femoral version resulted in a maximum mean difference of 18° (95% CI 16 to 20) between the most proximal (Lee et al) and most distal (Murphy et al) methods. Higher differences in proximal and distal femoral version measurement techniques were seen in femora with greater femoral version (r > 0.46; p < 0.001) and greater NSA (r > 0.37; p = 0.008) between all measurement methods. In the parametric 3D manipulation analysis, differences in femoral version increased 11° and 9° in patients with high and normal femoral version, respectively, with increasing NSA (110° to 150°). Conclusion. Measurement of femoral version angles differ depending on the method used to almost 20°, which is in the range of the aimed surgical correction in derotational femoral osteotomy and thus can be considered clinically relevant. Differences between proximal and distal measurement methods further increase by increasing femoral version and NSA. Measurement methods that take the entire proximal femur into account by using distal landmarks may produce more sensitive measurements of these differences. Cite this article: Bone Jt Open 2022;3(10):759–766

Talar body fractures are high energy intraarticular injuries that are best management by anatomical reduction and secure fixation to improve outcomes. The talus is relatively inaccessible surgically and requires extensive soft tissue dissection and/or osteotomies to gain adequate open visualisation. There are a small number of case reports on arthroscopic assisted fixation in the literature. This case series reports on the technique and early outcomes of six patients all of whom presented with significant intraarticular displacement and who were managed entirely arthroscopically. The fractures were of the main body of the talus involving the ankle and subtalar joints and all had preoperative CT scans. All six patients underwent posterior ankle and subtalar arthroscopy with cannulated screws used to stabilise the fractures after reduction. Visualisation of the fracture reduction was excellent. After 10 days in a backslab, the patients were protected in a boot and encouraged to actively move their ankles. Weight bearing was permitted once union appeared complete. There were no early complications of infection, avascular necrosis or VTE. There was one patient that had a non-clinically significant migration of a screw. Two patients were lost to follow up early due to being visitors. The mean length of follow up was 12 months in the remainder. The remaining four patients all returned to their preoperative level of activity. All had demonstrable subtalar stiffness. There was no early post-traumatic arthritis. This series represents the largest so far published. The main flaw in this report is the lack of long term follow up. While this report cannot state superiority over open techniques it is a safe, effective and acceptable technique that has significant conceptual benefits

Mixed Reality has the potential to improve accuracy and reduce required dissection for the performance of peri-acetabular osteotomy. The current work assesses initial proof of concept of MR guidance for PAO. A PAO planning module, based on preoperative computed tomography (CT) imaging, allows for the planning of PAO cut planes and repositioning of the acetabular fragment. 3D files (holograms) of the cut planes and native and planned acetabulum positions are exported with the associated spatial information. The files are then displayed on mixed reality head mounted device (HoloLens2, Microsoft) following intraoperative registration using an FDA-cleared mixed reality application designed primary for hip arthroplasty (HipInsight). PAO was performed on both sides of a bone model (Pacific Research). The osteotomies and acetabular reposition were performed in accordance with the displayed holograms. Post-op CT imaging was performed for analysis. Cutting plane-accuracy was evaluated using a best-fit plane and 2D angles (°) between the planned and achieved supra (SA)- and retroacetabular (RA) osteotomy and retroacetabular and ischial osteotomies (IO) were measured. To evaluate the accuracy of acetabular reorientation, we digitized the acetabular rim and calculated the acetabular opening plane. Absolute errors of planned and achieved operative inclination and anteversion (°) of the acetabular fragment, as well as 3D lateral-center-edge (LCE) angles were calculated. The mean absolute difference between the planned and performed osteotomy angles was 3 ± 3°. The mean absolute error between planned and achieved operative anteversion and inclination was 1 ± 0° and 0 ± 0° respectively. Mean absolute error between planned and achieved 3D LCE angle was 0.5 ± 0.7°. Mixed-reality guidance for the performance of pelvic osteotomies and acetabular fragment reorientation was feasible and highly accurate. This solution may improve the current standard of care by enabling reliable and precise reproduction of the desired acetabular realignment

The objective of this study was to use patient-specific finite element modeling to measure the 3D interfragmentary strain environment in clinically realistic fractures. The hypothesis was that in the early post-operative period, the tissues in and around the fracture gap can tolerate a state of strain in excess of 10%, the classical limit proposed in the Perren strain theory. Eight patients (6 males, 2 females; ages 22–95 years) with distal femur fractures (OTA/AO 33-A/B/C) treated in a Level I trauma center were retrospectively identified. All were treated with lateral bridge plating. Preoperative computed tomography scans and post-operative X-rays were used to create the reduced fracture models. Patient-specific materials properties and loading conditions (20%, 60%, and 100% body weight (BW)) were applied following our published method.[1]. Elements with von Mises strains >10% are shown in the 100% BW loading condition. For all three loading scenarios, as the bridge span increased, so did the maximum von Mises strain within the strain visualization region. The average gap closing (Perren) strain (mean ± SD) for all patient-specific models at each body weight (20%, 60%, and 100%) was 8.6% ± 3.9%, 25.8% ± 33.9%, and 39.3% ± 33.9%, while the corresponding max von Mises strains were 42.0% ± 29%, 110.7% ± 32.7%, and 168.4% ± 31.9%. Strains in and around the fracture gap stayed in the 2–10% range only for the lowest load application level (20% BW). Moderate loading of 60% BW and above caused gap strains that far exceeded the upper limit of the classical strain rule (<10% strain for bone healing). Since all of the included patients achieved successful unions, these findings suggest that healing of distal femur fractures may be robust to localized strains greater than 10%

The best treatment method of large acetabular bone defects at revision THR remains controversial. Some of the factors that need consideration are the amount of residual pelvic bone removed during revision; the contact area between the residual pelvic bone and the new implant; and the influence of the new acetabular construct on the centre of rotation of the hip. The purpose of this study was to compare these variables in two of the most used surgical techniques used to reconstruct severe acetabular defects: the trabecular metal acetabular revision system (TMARS) and a custom triflanged acetabular component (CTAC). Pre- and post-operative CT-scans were acquired from 11 patients who underwent revision THR with a TMARS construct for a Paprosky IIIB defect, 10 with pelvic discontinuity, at Royal Adelaide Hospital. The CT scans were used to generate computer models to virtually compare the TMARS and CTAC constructs using a semi-automated method. The TMARS construct model was calculated using postoperative CT scans while the CTAC constructs using the preoperative CT scans. The bone contact, centre of rotation, inclination, anteversion and reamed bone differences were calculated for both models. There was a significant difference in the mean amount of bone reamed for the TMARS reconstructions (15,997 mm. 3. ) compared to the CTAC reconstructions (2292 mm. 3. , p>0.01). There was no significant difference between overall implant bone contact (TMARS 5760mm. 2. vs CTAC 5447mm. 2. , p=0.63). However, there was a significant difference for both cancellous (TMARS 4966mm. 2. vs CTAC 2887mm. 2. , p=0.008) and cortical bone contact (TMARS 795mm. 2. vs CTAC 2560mm. 2. , p=0.001). There was no difference in inclination and anteversion achieved. TMARS constructs resulted on average in a centre of rotations 7.4mm more lateral and 4.0mm more posterior. Modelling of two different reconstructions of Paprosky IIIB defects demonstrated potential important differences between all variables investigated

Introduction. Our purpose is to analyze the true costs associated with preoperative CT scans performed for robotic assisted TKA planning and also to determine the value of a formal radiologist reading of these studies. Methods. We reviewed 194 CT scans of 176 sequential patients who underwent primary RTKA by a single surgeon at a suburban teaching hospital. CT radiology reports were reviewed for the presence of incidental findings that might result in change of care to the patient. Actual payments for technical and professional components of the CT scans were retrieved for 170 of the 176 patients. Any patient payments for the CT scan were also recorded. Results. In no CT scan report was there any findings other than arthritis in the knee and nothing was identified that lead to a recommendation for any additional testing. The mean total payment for a preoperative CT scan was $253 (range 0 – 912). The mean technical payment was $206 (range 0 – 856). The mean professional component paid was $48 (range 0 – 66). On average patients personally paid $56 (range 0 – 618). In 99/170 cases (58 %), the patients made no payment. For the remaining 71 patients the mean payment made was $134 (range 10 – 618). Discussion and Conclusion. No CT scan identified any clinical problem other than arthritis – this suggests that the professional component cost of this specific CT scan could be eliminated without harm to patients. The cost of the CT scan – mean <$300 – is low and a minimal part of the total overall cost of a primary TKA. Patients understand the value of the CT scan - preoperative advanced imaging helps ensure a precise and accurate intraoperative experience – and they are willing to pay for any of their costs related to this preoperative test. For figures, tables, or references, please contact authors directly

Background: A classification of intra-articular fractures of the distal radius is described on the basis of observations of consistent patterns of fracture fragmentation and displacement. The Melone intra-articular classification system categorizes articular fractures into 4 types, with the medial complex assuming a pivotal position as the cornerstone of both the radiocarpal and distal radio-ulnar joints. The purpose of this study was to classify AO type-C3 fractures according to the Melone classification system using preoperative CT scan data. Methods: We retrospectively reviewed the clinical records of all patients who underwent open reduction and internal fixation (ORIF), according to the AO type-C3 classification. Between September, 2006, and May, 2009, 36 patients and a total of 38 fractures were identified. These intra-articular fractures were also classified according to the Melone classification system using preoperative CT scan data. We also investigated a bone fracture type and surgicalprocedures. Results: Nine fractures were divided into Melone type-1, 17 into type-2 (anterior displacement), 6 into type-2 (posterior displacement), 2 into type-3, and 4 into type-4. Thirty fractures were treated using plate fixation, and 8 fractures were treated using nail fixation. Melone type-1 fractures were usually treated with nail fixation, whereas type-2, -3, and -4 fractures were usually treated using plate fixation. Conclusions: Classification according to the Melone classification system using preoperative CT scan data enables the identification and elucidation of displacement in the major fracture components and enables the establishment of rational guidelines for the management of ORIF

Introduction. Both navigation and instrumented bone referencing use unreliable intraoperative landmark identification or fixed referencing rules which don't reflect patient specific variability. PSI, however, lacks the flexibility to adapt to soft tissue factors not known during preoperative planning, in addition to suffering error from guide fit. A novel method of recreating surgical cut planes that combines preoperative image based identification of landmarks and planning with intraoperative adjustability is under development. This method uses an intraoperative 3D scan of the bone in conjunction with a preoperative CT scan to achieve the desired cuts and so avoids issues of intraoperative identification of landmarks. Method. During TKA surgery, a reference device is placed on the exposed femur. The device is used to position a target block which is pinned to the bone (see Figure 1). The condyles and target block are then scanned, the process taking a second to complete. This 3D scan is filtered to remove extraneous bodies and noise leaving only the bony geometry and target block (see Figure 2). The scan is then reconciled to the known bone geometry taken from preoperative CT scans. A cutting block is then fixed to the target block with a reference array visible to the camera attached. Pre-planned cut planes on a computer model of the bone are compared to the position and configuration of the distal cutting guide. Software guides the surgeon in real-time on the necessary configuration changes required to align the cutting block. The cut is performed on the distal femur, the cutting guide removed from the target-block, and a second scan performed. The software repeats the filtering and alignment processes and provides the surgeon with data on how closely the performed cut matches the alignment planned. Results. Two patients underwent this method alongside traditional alignment techniques. The initial 3D scan of the distal femoral condyles of the patients was matched to their corresponding CT scans. The first case had a mean error of 0.65 mm with 85% of errors falling below a magnitude of 1.16 mm and 58% falling below the case mean (see Figure 3). The second case had a mean error of 0.39 mm with 84% of errors falling below 0.70 mm and 60% falling below the case mean. It should be noted that the error introduced was due to the omission of soft tissue such as the PCL in the CT scan. Exposed bone portions of the scan geometry matched well with the CT scan, with error magnitudes significantly below the mean. Discussion. The ability to obtain useful surgical alignment using preoperatively identified landmarks, alongside the small space requirements of a modern 3D scanner is sharply contrasted against the large space requirements and need for intraoperative probing of traditional navigation systems. Likewise, the use of preoperative planning and landmark identification to overcome intraoperative data capture variability mirrors that of PSI, but allows for potentially much greater accuracy of execution as the issue of guide fit and topology variation is avoided while intraoperative flexibility is maintained

The discussion of outpatient unicompartmental knee arthroplasty (UKA) requires proof that it can be done safely and effectively, and also begs the question of whether it can be performed in an ambulatory surgery center (ASC) rather than a general hospital (which raises costs and is typically less efficient). Successful outpatient UKA requires carefully crafted algorithms/protocols, home support, preoperative planning and preparation, expectation management, risk stratification (not everyone is a candidate), perioperative pain management and buy-in from patients, support networks and the health care team. Relatively little data is available on the feasibility, safety and potential cost savings associated with this shift in care. We evaluated the costs and short term outcomes and complications of 150 consecutive UKAs performed in an ASC compared to those done in a general hospital both on an inpatient and outpatient basis. Determination of the setting of the outpatient surgery was made based on geographic preference by the patients; otherwise choice of inpatient or outpatient surgery in the hospital was left to the discretion of the surgeon and was primarily based on the patients' comorbidity profile and circumstances of home help. Total direct facility costs were calculated, including institutional supplies and services, anesthesia services, implants, additional PACU medications and services required, and costs associated with operating room use. Only total cost was evaluated, as it is the most consistent cost variable amongst the two institutions evaluated. The mean total direct cost of UKA in a general community hospital with an overnight stay was 1.24 and 1.65 times greater than the cost of UKA performed at the same hospital or an ASC on an outpatient basis, respectively. The mean total direct cost of outpatient UKA in a general hospital was 1.33 times greater than the mean total cost of UKA performed in an ASC. Semi-autonomous robotic technology has been introduced to optimise accuracy of implant positioning and soft tissue balance in UKA, with the expectation of resultant improvement in durability and implant survivorship. Currently, nearly 20% of UKA's in the U.S. are being performed with robotic assistance. It is anticipated that there will be substantial growth in market penetration over the next decade, projecting that nearly 37% of UKA's and 23% of TKA's will be performed with robotics in 10 years (Medical Device and Diagnostic Industry, March 5, 2015). First generation robotic technology improved substantially implant position compared to conventional methods; however, high capital costs, uncertainty regarding the value of advanced technologies, and the need for preoperative CT scans were barriers to broader adoption. Newer image-free robotic technology offers an alternative method for further optimizing implant positioning and soft tissue balance without the need for preoperative CT scans and with price points that make it suitable for use in an ASC. Currently, as a result of cost and other practical issues, <1% of first generation robotic technologies are being used in ASC's. Alternatively, more than 35% of second generation robotic systems are in use in ASC's for UKA, due to favorable pricing. In conclusion, UKA can be safely performed in the outpatient setting in select patients. Additionally, we demonstrated a substantial cost savings when UKA is performed in an outpatient setting and care is shifted from a general community hospital to an ASC. Finally, robotics can be utilised to optimise accuracy of implant placement and soft tissue balance in UKA, and newer image-free robotic technology is cost effective for outpatient UKA

The authors are not aware of any research comparing computed tomography (CT) and avascular necrosis (AVN) of the scaphoid bone. The primary aim of our study was to investigate the use of longitudinal CT in predicting AVN of the proximal pole of the scaphoid, and subsequent fracture nonunion following internal fixation. Thirty-two patients operated on by the senior author for scaphoid fracture were included. Preoperative CT scans were independently assessed for deformity, comminution, fracture position, proximal pole sclerosis, and bridging trabeculae. Intra-operative biopsy of the proximal pole was assessed independently by a blinded musculoskeletal histologist. AVN was determined by histology of a proximal pole biopsy, using the criteria described by Ficat. Post-operative CT scan was utilised to determine fracture union. Preoperative CT features which significantly correlated with AVN were, increased radiodensity of the proximal pole, the absence of any bridging trabeculae comminution, dorsal cortical angle, proximal fracture and age less than 20. Features predictive of subsequent nonunion were fractures of the proximal, increased radiodensity of the proximal pole, and AVN. Preoperative CT scan findings are significantly correlated with histologically confirmed AVN and fracture union. Preoperative longitudinal CT scan is of significant prognostic value and should be considered to assist in predicting outcome and assessing treatment options

Purpose of the study: The purpose of rotating the femoral piece, using an indepenent cut strategy, is to «correct» for epiphyseal torsion of the distal femur and thus obtain a biepicondylar axis parallel to the posterior bicondylar axis. It is known however that epiphyseal torsion of the distal femur is highly variable from one individual to another. Intraoperative identification of the biepicondylar line enables appropriate rotation, as long as the data collected are reliable. The purpose of this study was to determine the reliability of intraoperative biepicondylar axis measurements made with navigation systems and to compare the results with the preoperative scan taken as the gold standard. Material and methods: This prospective study included 60 degenerative knees undergoing total knee arthroplasty. The angle of epiphyesael rotation of the distal femur was measured on the preoperative computed tomography scan and intraoperatively with the navigation system which identified the biepicondylar line and the posterior bicondylar line. Statistical regression lines were determined. Results: The rotation measured on the preoperative scan was 7.1±2.4° and by the intraoperative navigation system 3.2±4.3°. There was a very weak statistical correlation between the preoperative measurement and the intraoperative navigation measurement (p=0.234, R =0.320). Discussion: Intraoperative identification of the biepicondylar axis is not reliable. Navigation does not enable an accurate assessment of the distal epiphyseal torsion of the femur and thus the proper rotation to give to the femoral piece. The only reliable measurement of the epiphyseal rotation of the distal femur is made on the preoperative computed tomography

Preoperative planning is a crucial step for total hip arthroplasty (THA), and 2D X-ray images are commonly used. The planning aims to provide the correct implant size, restore functional biomechanical conditions and avoid early complication such as dislocation, leg length discrepancy or abductors insufficiency. Limitations of 2D planning, besides the low accuracy in sizing, concerns the inability of planning the anteversion of both acetabular and femoral component on axial plane. Also, the verification of the planning intraoperatively is wholly left to qualitative measurements and the surgeon's experience. The need for having a more accurate and functional preoperative planning has been addressed using 3D models. The MyHip Planner (MHP) (Medacta International, Castel San Pietro, Switzerland), is a preoperative planning software which through artificial intelligent algorithm converts the CT scans into a 3D model that perfectly match the patient's anatomy. Then, automatic positioning of the implants is performed following the personal settings of the surgeon which will check and validate the planning, a personalized simulation of six daily activities to detect impingement of implants and bones. The MyHip Verifier (MHV) intraoperatively verifies the execution of the planning in terms of leg length and offset using two fluoroscopic images. Also, the size and cup angles can be calculated. The purpose of the present study was to validate the accuracy of the MHP [Fig 1] and MHV [Fig 2]. The dataset consisted of 13 patients who underwent primary uncemented THA. Each patient had a preoperative CT scan, intraoperative fluoroscopy, and postoperative CT scan after the surgery. The CT protocol used was low radiation (0,2 mm slicing for the pelvis, 0,5 mm for knees and ankles). The patients have been preoperatively planned used the MPH, and the accuracy of the components size prediction has been evaluated by comparing the preoperative planned values with the surgical reports. The MVH calculated the leg length and offset in terms of the difference between the preoperative and postoperative position of the femur concerning the pelvis. The accuracy of the measurements has been evaluated using postoperative CT scans. The MPH was able to predict the implanted size in 83% of the patient for the femoral stem and 96% for the acetabular component. The accuracy of the MVH in measuring the leg length was under 2 mm (1,6 ± 0,7 mm) while the offset was 2,5±1,6 mm. The cup angles were 5±1,1deg and 2,3±1,3deg for the anteversion and inclination, respectively. The average cup anteversion was 28,3°, mean cup inclination was 42,6°; femoral offset and leg length was restored in 96,5% of patients within a range of ±3 mm concerning the preoperative position. The results demonstrated the reliability of the MPH in predicting the implant size, and the accuracy of the MVH to verify the execution of the plan intraoperatively. The two software can be used in the clinical routine to improve the clinical outcome in THA. Limitations of this study are represented mainly by the small cohort of patients involved. For any figures or tables, please contact the authors directly

Image-guided TKR requires a three-dimensional model of the patient, traditionally provided by preoperative CT scans. Recent developments have focused on navigation systems that eliminate the need for preoperative CT scan. This paper aims to assess the comparative accuracy of prosthesis planning using CT-based and CT-free navigation systems. Four half-body cadavers were implanted with fiducial markers, four per limb, to provide accurate registration points. Eight orthopaedic surgeons then proceeded to plan the anatomy on each limb twice, using CT scan. The CT-free planning involved digitalisation of the fiducial markers, followed by attachment of trackers to the femur and tibia. Several kinematic and digitalisation steps were taken to produce a set of anatomical coordinates for each limb. Again each surgeon repeated this procedure twice on each limb. Calculation of reproducibility of the mechanical axis as defined by both methods was thus possible. The overall differences related to varus/valgus placements between the two methods were minor, with a mean of 0.04° (−0.20° to 0.28°) for the femur and 0.19° (−0.009° to 0.39°) for the tibia. The mean angular difference in flexion/extension placement was –0.27° (−0.59° to −0.08°) for the femur and −0.08° (−0.40° to 0.24°) for the tibia. Results for varus/valgus and flexion/extension, as measured by CT-based and CT-free systems, showed a high degree of concordance. There was no observable bias in either system, as shown by the approximately equal spread of data points on either side of the line of equality. The data show a high degree of reproducibility between CT-free navigation systems and CT-based procedures

Introduction:. Despite over 95% long-term survivorship of TKA, 14–39% of patients express dissatisfaction due to anterior knee pain, mid-flexion instability, reduction in range of flexion, and incomplete return of function. Changing demographics with higher expectations are leading to renewed interest in patient-specific designs with the goal of restoring of normal kinematics. Improved imaging and image-processing technology coupled with rapid prototyping allow manufacturing of patient-specific cutting guides with individualized femoral and tibial components with articulating surfaces that maximize bony coverage and more closely approximate the natural anatomy. We hypothesized that restoring the articular surface and maintaining medial and lateral condylar offset of the implanted knee to that of the joint before implantation would restore normal knee kinematics. To test this hypothesis we recorded kinematics of patient-specific prostheses implanted using patient-specific cutting guides. Methods:. Preoperative CT scans were obtained from nine matched pairs of human cadaveric knees. One of each pair was randomly assigned to one of two groups: one group implanted with a standard off-the-shelf posterior cruciate-retaining design using standard cutting guides based on intramedullary alignment; the contralateral knee implanted with patient-specific implants using patient-specific cutting guides, both manufactured from the preoperative CT scans. Each knee was tested preoperatively as an intact, normal knee, by mounting the knee on a dynamic, quadriceps-driven, closed-kinetic-chain Oxford knee rig (OKR), simulating a deep knee bend from 0° to 120° flexion. Following implantation with either the standard or patient-specific implant, knees were mounted on the OKR and retested. Femoral rollback, tibiofemoral rotation, tibial adduction, patellofemoral tilt and shift were recorded using an active infrared tracking system. Results:. To reduce the effect of variability, change in each kinematic measure was quantified as the absolute difference between the normal kinematic measure and the same measure after implantation (10° flexion increments). The cumulative difference from normal kinematics was calculated by summing the area beneath the curve (Fig 2). Cumulative differences in kinematics from normal were statistically lower for the patient-specific group compared to the standard group for all measures except patellar shift (Fig 2, paired t-test). Discussion:. Knee kinematics with the patient-specific design more closely approximated normal femoral rollback and tibial adduction than knees with the standard design. Femoral rollback is significantly closer qualitatively and quantitatively to normal in specimens implanted with patient-specific designs (Figs 1). The tibia rotated internally with flexion; however, the patient-specific group more closely approximated normal rotation. The patient-specific group more closely approximated normal tibial adduction suggesting ligament balance was better restored. Due to substantial differences in articular morphology among genders, races and patients, it is impossible to provide multiple sized implants to address the full range of inter-patient variability. Patient-specific designs that remove this variation, restore normal articular geometry, and maintain alignment are more likely to result in normal kinematics. Our results support the hypothesis that knees with patient-specific implants generate kinematics more closely resembling normal knee kinematics than standard knee designs. Clinical outcome studies are necessary to determine if our results translate into better outcomes

BACKGROUND. Total hip revision surgery in cases with previous multiple reconstructive procedures is a challenging treatment due to difficulties in treatment huge bone defects with standard revision prosthetic combinations. A new specially made production system in Electron-Beam Melting (EBM) technology based on a precise analysis of patients' preoperative CT scans has been developed. METHODS. Objectives of design customization in difficult cases are to correctly evaluate patient's anatomy, to plan a surgical procedure and to obtain an optimal fixation to a poor bone stock. The 3D Printing (EBM) technology permits to create an extremely flexible patient matching implant and instrument, with material performances not viable with standard manufacturing process. Dedicated visual 3D tools and instrumentations improve implants congruency according to preoperative plan. Primary stability is enhanced and tailored on patient's anatomy by means of press-fit, iliac stems and the high friction performances of Trabecular Titanium matrix. The use of bone screws and their position is designed to enhance primary stability, even in critical bone conditions, avoiding implant stress shielding and allowing bone integration. 4 cases (2 men and 2 women) of acetabular customized implants were performed. Mean age at surgery was 51.5 years (range 25–72). Patients were reviewed clinically and radiographically at follow-up. RESULTS. No signs of miss-match between intraoperative bone conditions and pre-operative planning were observed. No additional bone grafts or further native bone removal were needed. Biomechanical parameters were restored by using internal modularity (i.e. face-changers / angled spacers). Face-changers allow to correct coverage and anteversion of the acetabular system. Incompatibility or impingement between the stems and new acetabular component was not observed and stem revision was performed in one case. On-table stability proved excellent and no intraoperative complications were observed. All patients underwent an immediate mobilization with full weight-bearing. Mean Harris Hip Score increased significantly from 13.9 (range 6.9–20.6) preoperatively to 75.8 (range 53.9–94) at last follow-up (mean 17.5, range: 10–33), showing an improvement in terms of both pain relief, function and joint mobility. Radiographically neither signs of instability, migration nor tilting were observed. No case of dislocation nor infection were recorded. CONCLUSION. A detailed anatomical reconstruction, in-depth preoperative planning, custom-implant design, high performance of the 3D-printing technology, system modularity and patient-specific surgical tools permitted an effective restoration of the biomechanical joint parameters in these complex revision cases. The optimal primary stability of the implants promoted an early osseointegration with the remaining bone stock. Further studies shall be necessary to assess the performance of these Implants at long-term follow-up

Purpose of the study: Compar the position of the femoral piece in relation to the transepicondylar axis (TEA) using four different techniques for regulating rotation:. cut parallel to the posterior bicondylar line (BCL),. 3° external rotation,. spacer method,. application of the formula: rotation = 1° + space in extension/2. Material and methods: One hundred patients who underwent total knee arthroplasty (TKA) had a preoperative computed tomography (CT) scan. The surgical transepicondylar axis (TEA) and the BCL were drawn on the horizontal slices. The angle measured between these two lines (1.56°–2.5°) determined the theoretical angle of external rotation for aligning the femoral piece on the TEA. During the operation, femoral valgus was set to the HKS angle, measured by goniometry. The knife of the distal femoral cut, materializing the line perpendicular to the mechanical femoral axis, came in contact with the most distal femoral condyle (generally the medial condyle but occasionally the lateral condyle for varus femurs). The distance d between the knife and the most distal point of the condyle which remained distant was then measured. The external rotation was set at 0° and 3° with the techniques 1) and 2). For the technique 3), the asymmetry of the distal cut was projected on the posterior cut leading to an automatic rotation at an angle calculated trigonometrically. For the technique 4), the rotation was calculated as a function of the distance d. The difference between the external rotation obtained for each of these techniques and the theoretical rotation was calculated for each patient. Results: The mean error of rotation obtained for the four techniques was respectively: 2.2–1.9°; 2–1.7°; 1.8–2.2°; and 1.5–1.4° (p< 0.05). The rate of malrotations greater than 1° for the four techniques was respectively: 60%, 58%, 41% and 36%. The rate of malrotations greater than 2° was respectively: 45%, 44%, 27% and 21%. This rate varied according to the femoral morphotype. The percentage of malrotations greater than 2° by technique was as follows for femoral morphotypes normal, varus, and valgus: technique 1: 37,34,58%; technique 2: 37,53,40%; technique 3: 7.5,9,26%; technique 4:22,30,40%. Conclusion: Interindividual variations in the TEA-BCL angle explain the high rate of malrotation after regulated rotation. An adapted regulation will enable lesser risk of error. An adaptation taking into consideration the results of the preoperative CT scan appear to provide the most reliable results

Aims

To perform an incremental cost-utility analysis and assess the impact of differential costs and case volume on the cost-effectiveness of robotic arm-assisted unicompartmental knee arthroplasty (rUKA) compared to manual (mUKA).

Introduction. Most of patients with unilateral hip disease shows muscle volume atrophy of pelvis and thigh in the affected side because of pain and disuse, resulting in reduced muscle weakness and limping. However, it is unclear how the muscle atrophy correlated with muscle strength in the patient with hip disorders. A previous study have demonstrated that the volume of the gluteus medius correlated with the muscle strength by volumetric measurement using 3 dimensional computed tomography (3D-CT) data, however, muscles influence each other during motions and there is no reports focusing on the relationship between some major muscles of pelvis and thigh including gluteus maximus, gluteus medius, iliopsoas and quadriceps and muscle strength in several hip and knee motions. Therefore, the purpose of the present study is to evaluate the relationship between muscle volumetric atrophy of major muscles of pelvis and thigh and muscle strength in flexion, extension and abduction of hip joints and extension of knee joint before surgery in patients with unilateral hip disease. Material and Methods. The subjects were 38 patients with unilateral hip osteoarthritis, who underwent hip joint surgery. They all underwent preoperative computed tomography (CT) for preoperative planning. There were 6 males and 32 females with average age 59.5 years old. Before surgery, isometric muscle strength in hip flexion, hip extension, hip abduction and knee extension were measured using a hand held dynamometer (µTas F-1, ANIMA Japan). Major muscles including gluteus maximus, gluteus medius, iliopsoas and quadriceps were automatically extracted from the preoperative CT using convolutional neural networks (CNN) and were corrected manually by the experienced surgeon. The muscle volumetric atrophy ratio was defined as the ratio of muscle volume of the affected side to that of the unaffected side. The muscle weakness ratio was defined as the ratio of muscle strength of the affected side to that of the unaffected side. The correlation coefficient between the muscle atrophy ratio and the muscle weakness ratio of each muscle were calculated. Results. The average muscle atrophy ratio was 84.5% (63.5%–108.2%) in gluteus maximus, 86.6% (65.5%–112.1%) in gluteus medius, 81.0% (22.1%–130.8%) in psoas major, and 91.0% (63.8%–127.0%) in quadriceps. The average muscle strength ratio was 71.5% (0%–137.5%) in hip flexion, 88.1% (18.8%–169.6%) in hip abduction, 78.6% (21.9%–130.1%) in hip extension and 84.3% (13.1%–122.8%) in knee extension. The correlation coefficient between the muscle atrophy and the ratio of each muscle strength between the affected and unaffected side were shown in Table 1. Conclusion. In conclusion, the muscle atrophy of gluteus medius muscle, psoas major muscle and quadriceps muscle significantly correlated with the muscle weakness in hip flexion. The muscle atrophy of psoas major muscle and quadriceps muscle also significantly correlated with the muscle weakness in knee extension. There were no significant correlation between the muscle atrophy and the muscle weakness in hip extension and abduction

Although the introduction of ultraporous metals in the forms of acetabular components and augments has substantially improved the orthopaedic surgeon's ability to reconstruct severely compromised acetabuli, there remain some revision THAs that are beyond the scope of cups, augments, and cages. In situations involving catastrophic bone loss, allograft-prosthetic composites or custom acetabular components may be considered. Custom components offer the potential advantages of immediate, rigid fixation with a superior fit individualised to each patient. These custom triflange components require a preoperative CT scan with three-dimensional (3-D) reconstruction using rapid prototyping technology, which has evolved substantially during the past decade. The surgeon can fine-tune exact component positioning, determine location and length of screws, modify the fixation surface with, for example, the addition of hydroxyapatite, and dictate which screws will be locked to enhance fixation. The general indications for using custom triflange components include: (1) failed prior salvage reconstruction with cage or porous metal construct augments, (2) large contained defects with possible discontinuity, (3) known pelvic discontinuity, and (4) complex multiply surgically treated hips with insufficient bone stock to reconstruct using other means. We previously reported on our center's experience with 23 patients (24 hips) treated with custom triflange components with minimum 2-year follow-up. This method of reconstruction was used in a cohort of patients with Paprosky Type 3B acetabular defects, which represented 3% (30 of 955) of the acetabular revisions we performed during the study period of 2003 to 2012. At a mean follow-up of 4.8 years (range, 2.3 – 9 years) there were four subsequent surgical interventions: two failures secondary to sepsis, and one stem revision and one open reduction internal fixation for periprosthetic femoral fracture. There were two minor complications managed nonoperatively, but all of the components were noted to be well-fixed with no obvious migration or loosening observed on the most recent radiographs. Harris hip scores improved from a mean of 42 (SD ±16) before surgery to 65 (SD ±18) at latest follow-up (p < 0.001). More recently, we participated in a multi-center study of 95 patients treated with reconstruction using custom triflange components who had a mean follow-up of 3.5 years. Pelvic defects included Paprosky Type 2C, 3A, 3B and pelvic discontinuity. Concomitant femoral revision was performed in 21 hips. Implants used a mean of 12 screws with 3 locking screws. Twenty of 95 patients (21%) experienced at least one complication, including 6% dislocation, 6% infection, and 2% femoral-related issues. Implants were ultimately removed in 11% of hips. One hip was revised for possible component loosening. Survivorship with aseptic loosening as the endpoint was 99%. Custom acetabular triflange components represent yet another tool in the reconstructive surgeon's armamentarium. These devices can be helpful in situations of catastrophic bone loss, achieving reliable fixation. Clinical results are inferior to both primary THA and more routine revision THA. Patients and surgeons should be aware of the increased complications associated with these complex hip revisions