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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXI | Pages 13 - 13
1 Jul 2012
Subramanian AS Tsirikos AI
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Purpose of the study. To investigate the efficacy of pedicle screw instrumentation in correcting thoracolumbar/lumbar idiopathic scoliosis in adolescent patients. Summary of Background Data. Thoracolumbar/lumbar scoliosis has been traditionally treated through an anterior approach and instrumented arthrodesis with the aim to include in the fusion the Cobb-to-Cobb levels and preserve distal mobile spinal segments. Posterior instrumentation has been extensively used for thoracic or thoracic and lumbar scoliosis. In the advent of all-pedicle screw constructs there is debate on whether thoracolumbar/lumbar scoliosis is best treated through an anterior or a posterior instrumented arthrodesis. Methods. We reviewed the medical notes and radiographs of 19 consecutive adolescent patients with Lenke 5C idiopathic scoliosis (17 female-2 male, prospectively collected single surgeon's series). We measured the scoliosis, thoracic kyphosis and lumbar lordosis angles, apical vertebral rotation (AVR) and translation (AVT), trunk shift (TS), as well as the lower instrumented vertebra angle (LIVA) both pre-and post-operatively and at minimum 2-year follow-up. SRS 22 data was available for all patients. Results. All patients underwent posterior spinal arthrodesis of the primary thoracolumbar/lumbar curve using all-pedicle screw constructs. Mean age at surgery was 15.1 years. We identified 3 separate groups: Group 1 (9 patients) had a fusion to include the preoperative Cobb-to-Cobb levels of the curve; in Group 2 (8 patients) the fusion extended 1-2 levels distal (all patients) +/− proximal (4 patients) to the end Cobb vertebrae; in Group 3 (2 patients) the fusion extended to one level proximal to the lower end Cobb vertebra. Eight patients had compensatory thoracic curves. Mean Cobb angle before surgery was 60.3° (range: 43-91°). This was corrected by 79% to mean 13° (p<0.001) with no patient losing >2° correction at follow-up. Mean preoperative Cobb levels of the thoracolumbar/lumbar curve were 6.3; mean levels of instrumented fusion were 7 (mean extent of fusion: preoperative Cobb angle + 0.7 levels). Mean preoperative thoracic kyphosis was 34.7° and lumbar lordosis 45.3°. Mean postoperative thoracic kyphosis was 36.6° and lumbar lordosis 43°. Mean theatre time was 3.8 hours, hospital stay 7.5 days and intraoperative blood loss 0.26 blood volumes. There were no neurological complications other than one temporary brachial plexus neuropraxia (recovered before patient discharge from hospital), no wound infections or detected non-union at follow-up. Mean preoperative SRS 22 score was 3.7; this was improved to 4.5 at 2-year follow-up (p=0.01). Pain and self-image demonstrated significant improvement (p=0.02, p=0.001 respectively) with mean satisfaction rate 4.8. Comparison between Groups 1 and 2 showed similar age at surgery but higher preoperative scoliosis in Group 2 (Group 1: 54°/Group 2: 65°, p=0.05). Preoperative AVR, TS and LIVA were similar between the 2 groups (p>0.05). Preoperative AVT was significantly higher in Group 2 (Group 1: 3.3 cm/Group 2: 5 cm, p=0.01). Conclusion. Pedicle screw instrumentation can achieve excellent correction of Lenke 5C idiopathic scoliosis which is maintained at follow-up. This is associated with high patient satisfaction and low complication rates. Greater preoperative AVT and scoliosis angle predicted the need for longer fusion both distally and proximally beyond the end vertebra of the preoperative Cobb angle


Aim:. To determine radiographic variables that predict the need for distal extension of the fusion beyond Cobb-to-Cobb levels in treating thoracolumbar/lumbar (TL/L) scoliosis (Lenke 5) in adolescent patients. Method:. We reviewed the medical notes and radiographs of the senior author's consecutive series of 53 adolescent patients with TL/L scoliosis treated by posterior instrumented spinal arthrodesis using an all-pedicle screw construct. Our patients were categorised into 2 groups: patients with instrumented fusion between Cobb-to-Cobb levels of the TL/L curve (Group 1), and patients that required distal extension beyond the caudal Cobb level (Group 2). Pearson correlation and binary logistic regression analyses (significance p<0.05) were performed to identify variables that predict the need for distal extension. Results:. Groups 1 and 2 comprised 36 and 17 patients, respectively. The following preoperative parameters significantly correlated with distal extension of the fusion: TL/L scoliosis angle (TL/L), TL/L supine maximum lateral bending angle, TL/L apical vertebral translation (AVT), TL/L flexibility index (FI), lowest instrumented vertebra angle (LIVA), and compensatory thoracic scoliosis angle (TH). Binary logistic regression analysis optimised a predictive equation incorporating TL/L, AVT, FI, LIVA, and TH parameters that provides an 81% accuracy in predicting the need for Cobb-to-Cobb fusion or distal extension. There was no difference in demographic data or SRS-22 scores between the 2 groups. Discussion:. Regression analysis of preoperative radiographic variables can accurately predict the need for distal extension of the fusion beyond the preoperative Cobb-to-Cobb levels during posterior spinal arthrodesis in patients with adolescent idiopathic thoracolumbar/lumbar scoliosis. Conflict Of Interest Statement: No conflict of interest


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_14 | Pages 30 - 30
1 Mar 2013
Dachs R Dunn R
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Aim. To investigate anterior instrumented corrective fusion for thoracolumbar or lumbar scoliosis. Methods. A retrospective review of medical records and radiographs of 38 consecutively managed patients who underwent anterior spine surgery for thoracolumbar curves by a single surgeon between 2001 and 2011. The cohort consisted of 28 female and 10 male patients with idiopathic scoliosis as the commonest aetiology. Data collated and analysed included patient demographics, surgical factors, post-operative management and complications. In addition, radiographic analysis was performed on pre-operative and follow-up x-rays. Results. Thoracolumbar/lumbar curves were corrected from 70 to 27 degrees. The thoracic compensatory curve spontaneously corrected from 34 to 19 degrees. Sagittal imbalance of greater than 4 centimeters was found in 40 percent of patients preoperatively and in 16 percent post operatively (85 percent negative sagittal imbalance, 15 percent positive sagittal imbalance). Rotation according to the Nash-Moe method corrected by 1.13 of a grade. Average operative time was 194 minutes and estimated blood loss was 450 ml. The diaphragm was taken down in 36 of the 38 patients but no post-op ventilation was required. The average high care stay was 1.2 days. Average follow-up was 18 months. Good maintenance of correction was shown at most recent follow-up, with the mean thoracolumbar/lumbar curve measuring 29 degrees, and the mean compensatory thoracic curve measuring 21 degrees. There were no significant neurological or respiratory complications. Conclusion. Anterior corrective fusion for thoracolumbar and lumbar scoliosis is effective in both deformity correction and maintenance thereof. Spontaneous correction of the thoracic curve can be expected and thus limit the fusion to the lumbar curve. Despite the concerns of taking down the diaphragm, there is minimal morbidity. NO DISCLOSURES


Lowest instrumented vertebra (LIV) selection is critical to preventing complications following posterior spinal arthrodesis (PSA) for thoracolumbar/lumbar adolescent idiopathic scoliosis (TL/L AIS), but evidence guiding LIV selection is limited. This study aimed to investigate the efficacy of PSA using novel unilateral convex segmental pedicle screw instrumentation (UCS) in correcting TL/L AIS, to identify radiographic parameters correlating with distal extension of PSA, and to develop a predictive equation for distal fusion extension using these parameters. We reviewed data (demographic, clinical, radiographic, and SRS-22 questionnaires) preoperatively to 2-years' follow-up for TL/L AIS patients treated by PSA using UCS between 2006 to 2011. 53 patients were included and divided into 2 groups: Group-1 (n=36) patients had PSA between Cobb-to-Cobb levels; Group-2 (n=17) patients required distal fusion extension. A mean curve correction of 80% was achieved. Mean postoperative LIV angle, TL/L apical vertebra translation (AVT), and trunk shift were lower than previous studies. Six preoperative radiographic parameters significantly differed between groups and correlated with distal fusion extension: thoracic curve size, thoracolumbar curve size, LIVA, AVT, lumbar flexibility index, and Cobb angle on lumbar convex bending. Regression analysis optimised an equation (incorporating the first five parameters) which is 81% accurate in predicting Cobb-to-Cobb fusion or distal extension. SRS-22 scores were similar between groups. We conclude that TL/L AIS is effectively treated by PSA using UCS, six radiographic parameters correlate with distal fusion extension, and a predictive equation incorporating these parameters reliably informs LIV selection and the need for fusion extension beyond the caudal Cobb level


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 437 - 437
1 Aug 2008
Schwab F Farcy J Bridwell K Berven S Glassman S Horton W Shainline M
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Précis: A recently developed Classification of adult scoliosis was utilised to study surgical treatment in 339 patients. At 12 month follow up after surgery for thoracolumbar/lumbar scoliosis greatest improvement in outcome scores were noted in the following patients: lost lumbar lordosis, treatment with osteotomies, fusion to the sacrum for marked sagittal imbalance. Complication rates were greatest for: fusion to the sacrum, sagittal imbalance greater than 4cm. Introduction: A recently proposed radiographic Classification of adult scoliosis offers a useful system with high clinical impact and reliability. Continued work is required to apply this system in the development of treatment guidelines. The purpose of this study was to anal surgical treatment outcomes, and complications, by Classification subtype at 12 months post-operative follow up. Material and Method: This study included 339 patients: Type IV (thoracolumbar major) and Type V (lumbar major) adult scoliosis (Spinal Deformity Study Group). All patients had complete full-length spine radiographs and outcomes questionnaires (SRS, ODI and SF-12). An analysis of classification subtypes (modifiers) included outcome scores by surgical treatment. The latter included approach (anterior, posterior, both), use of osteotomies, and extension to the sacrum (or not). Results: Lordosis modifier was strongly correlated with baseline disability and post-operative improvement. Type C (loss of lordosis) patients had the lowest baseline outcome but also greatest improvement with surgery (p< 0.05). Subluxation modifier had impact on preoperative but not on postoperative outcomes measures. Marked sagittal balance had the worst outcomes of all groups if fusion fell short of the sacrum. Patients with osteotomies saw greater improvement than those without (p< 0.05). Anterior, posterior or combined procedures showed no significant difference in outcomes. Peri- and post-operative complications did not vary by lordosis modifier, subluxation modifier but were elevated for fusion to the sacrum (p< 0.05). Conclusion: At 12 month follow up for surgical treatment of adult thoracolumbar/lumbar scoliosis greatest improvement in outcome scores were noted in the following patients: lost lumbar lordosis, treatment with osteotomies, fusion to the sacrum for marked sagittal imbalance. Complication rates were greatest for: fusion to the sacrum, sagittal imbalance greater than 4cm. Further longitudinal follow up will permit validation of optimal treatment by Classification type of adult spinal deformity and refine patient and surgeon expectations of operative care


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 438 - 438
1 Aug 2008
Schwab F Farcy J Bridwell K Berven S Glassman S Horton W Shainline M
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Précis: A multi-centre prospective effort focused on analysis of a previously reported Classification of adult scoliosis. 809 thoracolumbar/lumbar deformities were studied. Radiographic analysis (deformity apex, lumbar lordosis, intervertebral subluxation), outcomes measures (ODI, SRS instruments) and surgical rates were examined. The Classification into Types, based on deformity apex location, and addition of modifiers (lordosis, subluxation) established clinically significant groups (disability, pain). In addition to high clinical impact, the Classification was also able to predict surgical rates. Introduction: A recently proposed radiographic classification of adult scoliosis offers a reliable method of categorizing patients. Continued work on this classification is expected to develop treatment guidelines. This investigation anald treatment patterns of a large patient population of thoracolumbar and lumbar adult scoliosis, emphasizing surgical rates and approaches by classification subtypes. Methods: This investigation anald 809 Type IV (thoracolumbar major) and Type V (lumbar major) curves from the Spinal Deformity Study Group database. Enrolled patients had complete SRS, ODI and SF-12 outcomes questionnaires and free standing full-length spine radiographs. Analysis compared non-operative versus surgical treatment (no imposed protocol) with surgical treatment assessed by approach (anterior, posterior, both), +/− osteotomies. Results: Of 809 patients, 348 were treated surgically (43%) and classified as lordosis type A (n=422), B (n=313), C (n=74). Surgical rates were greater for B vs. A (51% vs. 37%, p< 0.05)), trend for A vs. C (46%). Subluxation modifier scores: 0 (n=360), + (n=159), ++ (n=290). Surgical rates were greater for ++ vs. 0 (52% vs. 36 %, p< 0.05), trend vs. + (42 %). Greater sagittal imbalance was more likely to receive surgical treatment. Loss of lumbar lordosis (modifier B, C) was associated with increased osteotomy rates and posterior or circumferential treatment versus anterior only procedures (most common in modifier A). Greater subluxation (modifier ++) was associated with more circumferential surgery. Greater sagittal imbalance was associated with higher rate of posterior only surgery. Discussion: In this analysis, greater lordosis or subluxation modifier score was associated with higher surgical rates. Loss of lordosis and greater subluxation grade was associated with higher rates of circumferential surgery than lordotic spines or those without significant subluxation. This information suggests the ability of this classification system to predict treatment. Longitudinal follow up will permit validation of optimal treatment by classification of adult spinal deformity


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 516 - 516
1 Nov 2011
Bourghli A Obeid I Aurouer N Vital J
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Purpose of the study: Revision surgery for scoliosis in adults is a technical challenge. Indications include flat back, non-union, and syndromes adjacent to the instrumentation The purpose of this work was to evaluate the pertinence of the transforaminal lumbar interbody fusion (TLIF) method for revision surgery for scoliosis in adults. Material and methods: In our spinal surgery unit, 23 patients underwent revision surgery for thoracolumbar and lumbar scoliosis. A unique posterior approach was used. The TLIF was performed systematically at the lumbosacral level, at the non-union when it was present, and at the level of the Smith-Petersen osteotomies, as well as the levels above and below a transpedicular osteotomy. Seventeen patients presented flat back, ten non-union, five degenerative disease distal to the instrumentation and one degeneration proximal to the instrumentation. Nine patients had several indications for surgical revision. Five transpedicular osteotomies were performed in five patients. Results: Mean follow-up was 30 months (range 18–48). On average 2.3 levels (range 1–4) were involved in the TLIF. The fusion was extended to the sacrum in 22 patients. The mean operative time was 5h50m (range 3–8 hours). Mean blood loss was 2100ml (400–4500). Postoperative lumbar lordosis (L1S1) was 53.5°, giving an improvement of 23° copared with the preoperative lordosis. Among the postoperative complications, there was one neurological complications which recovered partially at last follow-up one case of deep infection of the operative site which require partial removal of the implants and one case of recurrent non-union. There was no loss of correction in the frontal or sagittal planes with the exception of one patient who developed an infection. None of the patients in the series required complementary anterior surgery. Conclusion: For revision surgery of scoliosis in the adult, a circumferential arthrodeis is needed to maintain the fusion. The TLIF method has the advantage of allowing intersomatic fusion via the posterior approach alone without opening the spinal canal. We consider that the TLIF technique is an alternative to two-phase procedures for revision surgery for scoliosis in adults. This method has given a good percentage of fusion in our series with little loss of correction


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_15 | Pages 9 - 9
7 Nov 2023
Blankson B Dunn R Noconjo L
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Adolescent idiopathic scoliosis (AIS) is a complex three-dimensional deformity of the spine characterized by a Cobb angle of at least 10 degrees. The goal of surgery is to not only prevent progression but restore sagittal and coronal balance, protecting cardiopulmonary function and improving cosmesis. We reviewed the impact of deformity correction surgery in terms of radiology and patient reported outcome(PROMs). The senior authors prospectively maintained database from 2003 –2022 was retrospectively analysed in terms of pre- and post-operative patient reported outcome measures (SRS 22) as well as radiological parameters. 44 patients with AIS were identified with pre and post op PROMS. The average age at surgery was 15yrs with 84% female. 38% had a Lenke 1 curve and 3 patients had Lenke 6 curves. 73% had posterior surgery. There was a total improvement in SRS 22 scores by 7.8%. Patients reported significant satisfaction with treatment 4.8/5 and improvement in self-image with a change of 0.4 (p<0.001). However, no difference in function, pain and mental health were recorded. Overall, proximal thoracic (PT) curves improved from 24 degrees to 11 degrees (p<0.001), Main thoracic (MT) curve 55 degrees to 19 degrees and Thoracolumbar/Lumbar curves (TL/L) 45 degreesto 11 degrees. Pre-operative flexibility and post-operative correction were 0.40 and 0.41 respectively for PT curve. MT was 0.32 and 0.67. That for TL/L was 0.57 and 0.71 respectively. Surgery yields significant main curve correction correlating with high patient reported satisfaction rate. Although total SRS 22 score yielded 7.8% improvement, sub-analysis of self-image showed the most significant improvement


The current study aims to compare the clinico radiological outcomes between Non-Fusion Anterior Scoliosis (NFASC) Correction and Posterior Spinal Fusion (PSF) for Lenke 5 curves at 2 years follow up. Methods:38 consecutive Lenke 5 AIS patients treated by a single surgeon with NFASC (group A) or PSF (group B) were matched by age, Cobb's angle, and skeletal maturity. Intraoperative blood loss, operative time, LOS, coronal Cobbs, and SRS22 scores at 2 years were compared. Flexibility was assessed by modified Schober's test. Continuous variables were compared using student t-tests and categorical variables were compared using chi-square. The cohort included 19 patients each in group A and B . Group A had M:F distribution of 1:18 while group B had 2:17. The mean age in group A and group B were 14.8±2.9 and 15.3±3.1 years respectively. The mean follow-up of patients in groups A and B were 24.5±1.8 months and 27.4±2.1 months respectively. Mean pre-op thoracolumbar/lumbar (TL/L) cobbs for group A and group B were 55°±7° and 57.5°±8° respectively. At two years follow up, the cobbs for group A and B were 18.2°±3.6° and 17.6°±3.5° respectively (p=0.09). The average operating time for groups A and B were 169±14.2 mins and 219±20.5 mins respectively (p<0.05). The average blood loss of groups A and B were 105.3±15.4 and 325.3±120.4 respectively (p<0.05). The average number of instrumented vertebra between groups A and B were 6.2 and 8.5 respectively (p<0.05). The average LOS for NFASC and PSF was 3.3±0.9 days and 4.3±1.1 days respectively (p<0.05). No statistically significant difference in SRS 22 score was noted between the two groups. No complications were recorded. Our study shows no significant difference in PSF and NFASC in terms of Cobbs correction and SRS scores, but the NFASC group had significantly reduced blood loss, operative time, and fewer instrumented levels. NFASC is an effective alternative technique to fusion to correct and stabilize Lenke 5 AIS curves with preservation of spinal motion


The current study aims to find the role of Enhance Recovery Pathway (ERP) as a multidisciplinary approach aimed to expedite rapid recovery, reduce LOS, and minimize morbidity associated with Non Fusion Anterior Scoliosis Correction (NFASC) surgery. A retrospective analysis of 35 AIS patients who underwent NFASC with Lenke 1 and Lenke 5 curves with a minimum of 1 year of follow-up was done. Patient demographics, surgical details, postoperative analgesia, mobilization, length of stay (LOS), patient satisfaction survey score with respect to information and care, and 90 days complications were collected. The cohort included 34 females and 1 male with a mean age of 15.2 years at the time of surgery. There were 16 Lenke 1 and 19 Lenke 5 in the study. Mean preoperative major thoracic and thoracolumbar/lumbar Cobb's angle were 52˚±7.6˚ and 51˚±4.5˚ respectively. Average blood loss and surgical time were 102 ±6.4 ml and 168 ± 10.2 mins respectively. Average time to commencing solid food was 6.5±1.5 hrs. Average time to mobilization following surgery was 15.5± 4.3 hrs. The average duration to the stopping of the epidural was 42.5±3.5 hrs. The average dose of opioid consumption intraoperatively was 600.5±100.5 mcg of fentanyl i.v. and 12.5±4.5 mg morphine i.v. Postoperatively opioids were administered via an epidural catheter at a dose of 2 mg of morphine every 24 hours up to 2 days and an infusion of 2mcg/hr of fentanyl along with 0.12-0.15% ropivacaine. The average duration to transition to oral analgesia was 55.5±8.5 hrs .20 patients had urinary catheter and the average time to removal of the catheter was 17.5±1.4 hrs. 25 patients had a chest tube and the average time to remove of chest tube was 25.5±3.2 hrs. The average length of hospital stay was 3.1±0.5 days. No patient had postoperative ileus or requirement of blood transfusion or any other complications. No correlation was found between LOS and initial cobb angle. The application of ERP in AIS patients undergoing NFASC results in reduced LOS and indirectly the cost, reduced post-operative opioid use, and overall improve patient satisfaction score


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXI | Pages 10 - 10
1 Jul 2012
Subramanian AS Tsirikos AI
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Purpose of the study. To compare the effectiveness of unilateral and bilateral pedicle screw techniques in correcting adolescent idiopathic scoliosis. Summary of Background Data. Pedicle screw constructs have been extensively used in the treatment of adolescent patients with idiopathic scoliosis. It has been suggested that greater implant density may achieve better deformity correction. However, this can increase the neurological risk related to pedicle screw placement, prolong surgical time and blood loss and result in higher instrumentation cost. Methods. We reviewed the medical notes and radiographs of 139 consecutive adolescent patients with idiopathic scoliosis (128 female-11 male, prospectively collected single surgeon's series). We measured the scoliosis, thoracic kyphosis (T5-T12), and lumbar lordosis (L1-L5) before and after surgery, as well as at minimum 2-year follow-up. SRS 22 data was available for all patients. Results. All patients underwent posterior spinal arthrodesis using pedicle screw constructs. Mean age at surgery was 14.5 years. We had 2 separate groups: in Group 1 (43 patients) correction was performed over 2 rods using bilateral segmental pedicle screws; in Group 2 (96 patients) correction was performed over 1 rod using unilateral segmental pedicle screws with the 2. nd. rod providing stability of the construct through 2-level screw fixation both proximal and distal. Group 1. Mean Cobb angle before surgery for upper thoracic curves was 37°. This was corrected by 71% to mean 11° (p<0.001). Mean Cobb angle before surgery for main thoracic curves was 65°. This was corrected by 71% to mean 20° (p<0.001). Mean Cobb angle before surgery for thoracolumbar/lumbar curves was 60°. This was corrected by 74% to mean 16° (p<0.001). No patient lost >2° correction at follow-up. Mean preoperative thoracic kyphosis was 24° and lumbar lordosis 52°. Mean postoperative thoracic kyphosis was 21° and lumbar lordosis 50° (p>0.05). Mean theatre time was 5.5 hours, hospital stay 8.2 days and intraoperative blood loss 0.6 blood volumes. Complications: 1 transient IOM loss/no neurological deficit; 1 deep wound infection leading to non-union and requiring revision surgery; 1 rod trimming due to prominent upper end. Mean preoperative SRS 22 score was 3.9; this improved to 4.5 at follow-up (p<0.001). Pain and self-image demonstrated significant improvement (p=0.001, p<0.001 respectively) with mean satisfaction rate 4.9. Group 2. Mean Cobb angle before surgery for upper thoracic curves was 42°. This was corrected by 52% to mean 20° (p<0.001). Mean Cobb angle before surgery for main thoracic curves was 62°. This was corrected by 70% to mean 19° (p<0.001). Mean Cobb angle before surgery for thoracolumbar/lumbar curves was 57°. This was corrected by 72% to mean 16° (p<0.001). No patient lost >2° correction at follow-up. Preoperative scoliosis size for all types of curves correlated with increased surgical time (r=0.6, 0.4). Mean preoperative thoracic kyphosis was 28° and lumbar lordosis 46°. Mean postoperative thoracic kyphosis was 25° and lumbar lordosis 45° (p>0.05). Mean theatre time was 4.2 hours, hospital stay 8.4 days and intraoperative blood loss 0.4 blood volumes. Complications: 1 deep and 1 superficial wound infections treated with debridement; 1 transient brachial plexus neurapraxia; 1 SMA syndrome. Mean preoperative SRS 22 score was 3.7; this improved to 4.5 at follow-up (p<0.001). Pain, function, self-image and mental health demonstrated significant improvement (p<0.001 for all parameters) with mean satisfaction rate 4.8. Comparison between groups showed no significant difference in regard to age at surgery, preoperative and postoperative scoliosis angle for main thoracic and thoracolumbar/lumbar curves, as well as SRS scores and length of hospital stay. Better correction of upper thoracic curves was achieved in Group 1 (p<0.05), but upper thoracic curves in Group 2 were statistically more severe before surgery (p<0.05). Increased surgical time and blood loss was recorded in Group 1 (p<0.05, p=0.05 respectively). The implant cost was reduced by mean 35% in Group 2 due to lesser number of pedicle screws. Conclusion. Unilateral and bilateral pedicle screw instrumentation has achieved excellent deformity correction in adolescent patients with idiopathic scoliosis, which was maintained at follow-up. This has been associated with high patient satisfaction and low complication rates. The unilateral technique using segmental pedicle screw correction has reduced surgical time, intraoperative blood loss and implant cost without compromising surgical outcome for the most common thoracic and thoracolumbar/lumbar curves. The bilateral technique achieved better correction of upper thoracic scoliosis


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 238 - 238
1 Sep 2005
Tokala D Mukerjee K Grevitt M
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Study design: Retrospective study. Objectives: To determine whether apical vertebrectomy for correction of severe spinal deformity in patients with cerebral palsy or mental retardation significantly improves curve correction and to study complications of such a procedure. Summary of Background data: Although a combined anterior-posterior procedure for correction of severe deformity in cerebral palsy patients is well established, apical vertebrectomy to improve correction has not been described. Subjects: 5 patients (2M, 3F) operated on between 2000–2003 (anterior apical vertebrectomy followed by posterior instrumented fusion), mean age 14 years, average follow-up 1.5 years. All had group II (Lonstein & Akbarnia) rigid (mean 96degrees bending to 83degrees) thoracolumbar/lumbar curves with marked pelvic obliquity. Results: Preoperative mean Cobb angle of 96 degrees corrected to 36 degrees, (63% correction, and 57% correction over and above the bending Cobb angle), 42 degrees at final follow-up. Mean apical vertebral translation (AVT) correction was 57 % (86mm to 37mm) and regional AVT correction 53%. Pelvic tilt correction was 72% (29degrees to 9degrees). Thoracic kyphosis remained unchanged but lumbar lordosis of 4.2 degrees (range−66 to +68) was corrected to 63 degrees. Mean blood loss was 1100mls (range 300–3000) for anterior surgery and 3400mls for posterior surgery. Operative time was 3 hours for anterior surgery. There were no intra-operative or post-operative complications (infection, pseudarthrosis, metalwork failure). Subjective outcome was excellent in all patients. Conclusion: In patients with rigid, rotated curves with wide apical translation, apical vertebrectomy and posterior instrumented fusion can achieve significant correction of Cobb angle over and above the bending cobb angle and also the AVT and pelvic tilt leading to high parent / caregiver satisfaction and improvement in functional status of the patient


Bone & Joint Open
Vol. 4, Issue 9 | Pages 689 - 695
7 Sep 2023
Lim KBL Lee NKL Yeo BS Lim VMM Ng SWL Mishra N

Aims

To determine whether side-bending films in scoliosis are assessed for adequacy in clinical practice; and to introduce a novel method for doing so.

Methods

Six surgeons and eight radiographers were invited to participate in four online surveys. The generic survey comprised erect and left and right bending radiographs of eight individuals with scoliosis, with an average age of 14.6 years. Respondents were asked to indicate whether each bending film was optimal (adequate) or suboptimal. In the first survey, they were also asked if they currently assessed the adequacy of bending films. A similar second survey was sent out two weeks later, using the same eight cases but in a different order. In the third survey, a guide for assessing bending film adequacy was attached along with the radiographs to introduce the novel T1-45B method, in which the upper endplate of T1 must tilt ≥ 45° from baseline for the study to be considered optimal. A fourth and final survey was subsequently conducted for confirmation.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 196 - 197
1 Mar 2003
Ouellet J Webb J
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Introduction: Historically, anterior spinal surgery for scoliosis has led to better coronal correction, though at the expense of sagittal alignment specifically at the thoracolumbar junction. The purpose of the study was to ascertain the effectiveness in maintenance of coronal and sagittal balance of anterior spinal surgery and instrumentation for AIS. Methods: 17 patients with idiopathic scoliosis treated with anterior spinal fusion using a single rod AO USS construct were reviewed in a retrospective fashion. Inclusion in study group required a minimum two years follow-up with complete radiographic and clinical follow up. Results: There were 14 lumbar curves of which seven were King I and seven thoracolumbar / lumbar curves. Seven patients had supplemental structural anterior support in the lumbar spine. Four had femoral allograft rings and three had cages (2 Harms, 1 Synex cages). Three thoracic curves were operated on of which two were King III, and one King II. The mean pre-operative Cobb angle was corrected from 48° to 14° post-op and 16° on the last follow-up (24 to 53 months) representing 71% of correction. Apical vertebral translation was corrected to 70%, comparable to the 60% correction of trunk shift at last follow-up. Sagittal contour of instrumented segment for the thoracic curve did not change. The pre-operative sagittal contour across the instrumented levels for the 14 1umbar was 5.6° of lordosis which changed to 0.5° of lordosis post-operatively. At last follow-up it was 2° of kyphosis. Specifically there were 7 of 14 that had greater that 10° of surgically induced kyphosis across the fusion mass. At last follow-up three patients had further kyphosis across the instrumented levels. The overall sagittal vertical axis did not change irrespective of the focal sagittal alignment. There was a net increase in lumbar lordosis below the fusion mass. Three patients had asymptomatic pseudoarthroses. There was no failure of instrumentation and no patient required further surgery. Conclusion: The authors conclude that single rod anterior spinal instrumentation for AIS is effective in maintaining coronal and sagittal alignment though one needs to pay particular attention to sagittal contour. The increase in lumbar lordosis below the fusion may well explain the maintained sagittal balance


Bone & Joint Open
Vol. 5, Issue 3 | Pages 243 - 251
25 Mar 2024
Wan HS Wong DLL To CS Meng N Zhang T Cheung JPY

Aims

This systematic review aims to identify 3D predictors derived from biplanar reconstruction, and to describe current methods for improving curve prediction in patients with mild adolescent idiopathic scoliosis.

Methods

A comprehensive search was conducted by three independent investigators on MEDLINE, PubMed, Web of Science, and Cochrane Library. Search terms included “adolescent idiopathic scoliosis”,“3D”, and “progression”. The inclusion and exclusion criteria were carefully defined to include clinical studies. Risk of bias was assessed with the Quality in Prognostic Studies tool (QUIPS) and Appraisal tool for Cross-Sectional Studies (AXIS), and level of evidence for each predictor was rated with the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) approach. In all, 915 publications were identified, with 377 articles subjected to full-text screening; overall, 31 articles were included.


Bone & Joint Open
Vol. 5, Issue 10 | Pages 886 - 893
15 Oct 2024
Zhang C Li Y Wang G Sun J

Aims

A variety of surgical methods and strategies have been demonstrated for Andersson lesion (AL) therapy. In 2011, we proposed and identified the feasibility of stabilizing the spine without curettaging the vertebral or discovertebral lesion to cure non-kyphotic AL. Additionally, due to the excellent reunion ability of ankylosing spondylitis, we further came up with minimally invasive spinal surgery (MIS) to avoid the need for both bone graft and lesion curettage in AL surgery. However, there is a paucity of research into the comparison between open spinal fusion (OSF) and early MIS in the treatment of AL. The purpose of this study was to investigate and compare the clinical outcomes and radiological evaluation of our early MIS approach and OSF for AL.

Methods

A total of 39 patients diagnosed with AL who underwent surgery from January 2004 to December 2022 were retrospectively screened for eligibility. Patients with AL were divided into an MIS group and an OSF group. The primary outcomes were union of the lesion on radiograph and CT, as well as the visual analogue scale (VAS) and Oswestry Disability Index (ODI) scores immediately after surgery, and at the follow-up (mean 29 months (standard error (SE) 9)). The secondary outcomes were total blood loss during surgery, operating time, and improvement in the radiological parameters: global and local kyphosis, sagittal vertical axis, sagittal alignment, and chin-brow vertical angle immediately after surgery and at the follow-up.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVII | Pages 9 - 9
1 Jun 2012
Hamzaoglu A Berk H Alanay A Ozturk C
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Introduction. The potential structural effect of the sacral tilt on the development of disc wedging adjacent to lowest instrumented vertebra (LEV), and consequent postoperative coronal trunk decompensation in the surgical treatment of idiopathic scoliosis are well known. The aim of this study is firstly to establish the possible role of sacral tilt, limb length inequality, and associated pelvic girdle anomalies in the cause of idiopathic scolisosis, and secondly to determine the effect of sacral tilt on adjacent disc wedging below LEV in some idiopathic curves such as thoracolumbar/lumbar curves, and double major curves postoperatively. Methods. Between 2006 and 2008, 159 patients with idiopathic scoliosis from outpatient clinics were included in analyses. In all patients, standing posteroanterior and lateral spinal column and Ferguson radiographs were routinely taken. If direct radiographs suggested iliac bone asymmetry, hemi-pelvis volume measurements were done with CT scan. Curve type, sacral tilt, L5 tilt, iliac asymmetry, and limb-length differences were measured. As a second part of study, 87 surgically treated patients with double major curves were examined retrospectively in terms of adjacent subjacent disc wedging below LEV and sacral tilt. Results. In the first part of the study, the mean age of patients was 14·21 years (range 2–25) and all but 14 were female. The curve types were lumbar in 31 patients, thoracolumbar in 42, double major in 55, thoracic in 27, and triple in four. Sacral tilt towards the convex side of TL/L curve was present in 117 (74%) patients with an average of 8° measured from Ferguson graphs. L5 tilt towards the convex side of TL/L curve, and limb length inequality of less than 5 mm on the convex side of TL/L curve were more prevalent in patients with sacral tilt (57%) than in those without sacral tilt (p=0·021). On hemi-pelvis volume measurement, patients with no sacral tilt (n=42) had no difference in both sides whereas patients with sacral tilt (n=117) showed significant difference, with the convex side being smaller. We noted a correlation between L5 tilt and sacral tilt (p=0·048) and between sacral tilt and hemi-pelvis volume (p=0·024). There was no correlation between sacral tilt and pelvic asymmetry, age, sex, curve type, or amount of limb length inequality. In the second part of the study, disc wedging adjacent to LEV was present in 75 of 87 patients and sacral tilt was present in 72 of 75 (96%) (p=0·008). Six patients had limb length inequality of more than 1 cm, showing the postoperative trunk decompensation, which was corrected by elevating the shorter leg by shoe-lift. Conclusions. This study revealed significant association between sacral tilt and hemi-pelvis hypoplasia independent from age. This association may have a primary role in the cause of this disease. Although LEV is paralel to pelvis, intervertebral disc adjacent to LEV is often wedged and there is lumbosacral hemicurve distally below the instrumentation in patients treated by either anterior or posterior surgery. We believe that lumbosacral hemicurve due to sacral tilt behaves like hemivertebra, which is impossible to detect with preoperative standing anteroposterior radiographs. Ferguson view is necessary to detect the sacral tilt. The postoperative trunk decompensation is greater with presence of sacral tilt and limb length inequality


Bone & Joint Open
Vol. 3, Issue 1 | Pages 85 - 92
27 Jan 2022
Loughenbury PR Tsirikos AI

The development of spinal deformity in children with underlying neurodisability can affect their ability to function and impact on their quality of life, as well as compromise provision of nursing care. Patients with neuromuscular spinal deformity are among the most challenging due to the number and complexity of medical comorbidities that increase the risk for severe intraoperative or postoperative complications. A multidisciplinary approach is mandatory at every stage to ensure that all nonoperative measures have been applied, and that the treatment goals have been clearly defined and agreed with the family. This will involve input from multiple specialities, including allied healthcare professionals, such as physiotherapists and wheelchair services. Surgery should be considered when there is significant impact on the patients’ quality of life, which is usually due to poor sitting balance, back or costo-pelvic pain, respiratory complications, or problems with self-care and feeding. Meticulous preoperative assessment is required, along with careful consideration of the nature of the deformity and the problems that it is causing. Surgery can achieve good curve correction and results in high levels of satisfaction from the patients and their caregivers. Modern modular posterior instrumentation systems allow an effective deformity correction. However, the risks of surgery remain high, and involvement of the family at all stages of decision-making is required in order to balance the risks and anticipated gains of the procedure, and to select those patients who can mostly benefit from spinal correction.


The Bone & Joint Journal
Vol. 102-B, Issue 12 | Pages 1703 - 1708
1 Dec 2020
Miyanji F Pawelek J Nasto LA Simmonds A Parent S

Aims

Spinal fusion remains the gold standard in the treatment of idiopathic scoliosis. However, anterior vertebral body tethering (AVBT) is gaining widespread interest, despite the limited data on its efficacy. The aim of our study was to determine the clinical efficacy of AVBT in skeletally immature patients with idiopathic scoliosis.

Methods

All consecutive skeletally immature patients with idiopathic scoliosis treated with AVBT enrolled in a longitudinal, multicentre, prospective database between 2013 and 2016 were analyzed. All patients were treated by one of two surgeons working at two independent centres. Data were collected prospectively in a multicentre database and supplemented retrospectively where necessary. Patients with a minimum follow-up of two years were included in the analysis. Clinical success was set a priori as a major coronal Cobb angle of < 35° at the most recent follow-up.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 108 - 108
1 Mar 2009
Ramieri A Cellocco P Barci V Costanzo G
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Introduction: Currently, percutaneous vertebroplasty and kyphoplasty are commonly used for the treatment of vertebral osteoporotic compression fractures (Phillips et al., 2003). Even without fractures, an osteoporotic vertebral body may develop some structural modifications with dystrophic features, defined as “intravertebral clefts” and “intravertebral vacuum” (Missori et al, 2005). These conditions may be painful and the MRI is the imaging technique of choice for their evaluation. Materials and methods: A prospective consecutive series of 21 elderly patients with pain in the thoracolumbar or lumbar spine were evaluated. MRI findings showed modifications of the vertebral body consistent with algodystrophy. Lesions were treated by means of percutaneous augmentation with PMAA, using a single pedicle approach. The outcomes of such procedure were evaluated with a visual analogue scale for pain (Chen et al, 2005). Results and conclusions: Percutaneous augmentation has not determined any complications neither early nor late. Outcomes have showed to be good or excellent, except for a patient with insufficient amount of injected PMMA. Augmentation of the vertebral body showed to be effective in reducing or solving pain, in spite of the biomechanical alterations due to algodystrophic phenomena. During kyphoplasty, particularly when performed for painful Schmorl nodes, balloon inflation creates a positive pressure room inside the vertebral body opposed to the negative pressure caused by abnormality of the discovertebral junction. This phenomenon makes it possible to fill the vacuum with PMMA without the risk of cement leakage