Long femoral nails for neck of femur fractures and prophylactic fixation have a risk of anterior cortex perforation. Previous studies have demonstrated the radius of curvature (ROC) of a femoral nail influencing the finishing point of a nail and the risk of anterior cortex perforation. This study aims to calculate a patients femoral ROC using preoperative XR and CT and therefore nail finishing position. We conducted a retrospective study review of patients with long femoral cephalomedullary nailing for proximal femur fractures (OTA/AO 31(A) and OTA/AO 32) or impending pathological fractures at a level 1 trauma centre between January 1, 2015 and December 31, 2020 with both full length lateral X-ray and CT imaging. Femoral ROC was calculated on both imaging modalities. Outcomes measured including nail finishing position, anterior cortex encroachment and impingement. The mean femoral ROC was 1026mm on CT and 1244mm on XR. CT femoral ROC strongly correlated with nail finishing point with a spearmans coefficient of 0.77. Additionally, femurs with a ROC <1000mm were associated with a higher risk of anterior encroachment (OR 6.12) and femurs with a ROC <900mm were associated with a higher risk of anterior cortex impingement (OR 6.47). To our knowledge this is the first study to compare a measured femoral ROC to nail finishing position. The use of CT to measure femoral ROC and to a lesser extent XR was able to predict both nail finishing position and risk of anterior cortex encroachment. Preoperative XRs and CTs were able to identify patients with a small femoral ROC. This predicted patients at risk of anterior cortex impingement, anterior cortex encroachment and nail finishing position. We may be able to select femoral nails that resemble the native femoral ROC and mitigate the risk of anterior cortex perforation

Summary. The significance of matching radius of curvature of the radial head implant and the capitellum in implant selection is evaluated. A mismatch of radius of curvature could lead to point loading, reducing contact area, creating large contact stresses, resulting in arthritis, pain, and other complications. Introduction. Radial head (RH) implant size is chosen by reconstruction outside of the radiocapitellar joint capsule measuring the RH diameter and length, which is replicated for implant selection. RH radius of curvature (RC) is rarely part of the decision although important in determining contact area. Methods. Eleven fresh-frozen cadaver humeri were denuded, with articular cartilage intact. These were held horizontally in an MTS machine; capitellum faced up, and covered with a Tekscan transducer. RH implants were attached by vice to the MTS driving piston. Four different RH implant models were compared: Ascension, Integra Katalyst, Stryker Small and Medium, all CoCr. All implants were 21mm in outer diameter, except the Stryker small implant (18mm). Cyclic axial loading was applied through the RH implant to the capitellum. Contact area and stress concentrations were captured by the transducer. Loading was applied with stroke control until steady state loading occurred between specified values of 115N-65N, within 1N of peak and 5N of base values. Using the Stryker 21mm implant loading at 155N-65N and 195N-105N simulated over-sizings of +2mm and +4mm. Results. Percent difference between RH and Capitellar RC's were plotted against corresponding Contact Areas of 21mm sized RH implants, and a linear regression done. Negative values corresponded with larger RH than capitellar RC values. The resulting slope was 92.19, showing a significant increase in contact area with decreased RH to capitellar ratios, with an R. 2. value of 0.8122, showing a linear trend. Total stresses were calculated for all maximum contact areas, using the peak values. Discussion. Clinical RH implant sizing comes from native head diameter, not curvature. Improper RC could lead to point loading, reducing contact area, creating large contact stresses, resulting in arthritis, pain, and other complications. This can be seen through the linear relation between contact area and RC. With an RH implant RC of greater value than capitellar RC, the contact area decreases significantly, resulting in increased stress. The significance of RC matching in implant selection. Increases in stress are greater for differences in RC values, than for improper sizing of diameter (D=85.7%) or length (+2mm, +4mm). With the decrease in contact area with increased implant RC, and the changes in stress compared to improper sizings (length and diameter), it can be seen that implant RC is an important feature in RH implant selection

Clinically significant proximal junctional kyphosis (PJK) occurs in 20% of children treated with posterior distraction-based growth friendly surgery. In an effort to identify modifiable risk factors, it has been theorized biomechanically that low radius of curvature (ROC) implants (i.e., more curved rods) may increase post-operative thoracic kyphosis, and thus may pose a higher risk of developing PJK. We sought to test the hypothesis that EOS patients treated with low ROC (more curved rods) distraction-based treatment will have a greater risk of developing PJK as compared to those treated with high ROC (straighter) implants. This is a retrospective review of prospectively collected data obtained from a multi-centre EOS database on children treated with rib-based distraction with minimum 2-year follow-up. Variables of interest included: implant ROC at index (220 mm or 500 mm), patient age, pre-operative scoliosis, pre-operative kyphosis, and scoliosis etiology. In the literature, PJK has been defined as clinically significant if revision surgery with superior extension of the upper instrumented vertebrae was performed. In 148 scoliosis patients, there was a higher risk of clinically significant PJK with low ROC (more curved) rods (OR: 2.6 (95%CI 1.09-5.99), χ2 (1, n=148) = 4.8, p = 0.03). Patients had a mean pre-operative age of 5.3 years (4.6y 220 mm vs 6.2y 500 mm, p = 0.002). A logistic regression model was created with age as a confounding variable, but it was determined to be not significant (p = 0.6). Scoliosis etiologies included 52 neuromuscular, 52 congenital, 27 idiopathic, 17 syndromic with no significant differences in PJK risk between etiologies (p = 0.07). Overall, patients had pre-op scoliosis of 69° (67° 220mm vs 72° 500mm, p = 0.2), and kyphosis of 48° (45° 220mm vs 51° 500mm, p = 0.1). The change in thoracic kyphosis pre-operatively to final follow up (mean 4.0 ± 0.2 years) was higher in patients treated with 220 mm implants compared to 500 mm implants (220 mm: 7.5 ± 2.6° vs 500 mm: −4.0 ± 3.0°, p = 0.004). Use of low ROC (more curved) posterior distraction implants is associated with a significantly greater increase in thoracic kyphosis which likely led to a higher risk of developing clinically-significant PJK in EOS patients

End-stage osteoarthritis is characterised by pain and reduced physical function, for which total knee arthroplasty (TKA) is recognised to be a highly effective treatment. Most implants are multi radius in design, though modern kinematic theory suggests a single flexion/extension axis is located in the femur. A recently launched TKA implant (Triathlon, Stryker US), is based on this theory, adopting a single radius of curvature femoral component. It is hypothesised that this design allows better function, and specifically, that it results in enhanced efficiency of the quadriceps group through a longer patello-femoral moment arm. Change in power output was compared between single and multi radius implants as part of a larger ongoing randomised controlled trial to benchmark the new implant. Power output was assessed using a Leg Extensor Power Rig, well validated for use with this population, pre-operatively and at 6, 26 and 52 weeks post-operatively in 101 Triathlon and 82 Kinemax implants. All patients were diagnosed with osteoarthritis, and drawn from a single centre. Output was reported as maximal wattage (W) generated in a single leg extension, and expressed as a proportion of the contralateral limb power output to act as an internal control. The results are shown in the table below. Two-way repeated measures ANOVA demonstrated a significant effect of TKA on the quadriceps power output, F = 249.09, p = <0.001 and also a significant interaction of the implant group on the output F = 11.33, p = 0.001. Independent samples t-tests of between group differences at the four assessment periods highlighted greater improvement in the single radius TKA group at all post-operative assessments (p <0.03), see table. The theoretical enhanced quadriceps efficiency conferred by single radius design was found in this study. Power output was significantly greater at all post-operative assessments in the single radius compared to the multi radius group. This difference was particularly relevant at early 6 week and 1 year assessment. Lower limb power output is known to link positively to functional ability. The results support the hypothesis that TKAs with a single radius design have enhanced recovery and better function

The August 2013 Trauma Roundup. 360 . looks at: reverse oblique fractures do better with a cephalomedullary device; locking screws confer no advantage in tibial plateau fractures; it’s all about the radius of curvature; radius of curvature revisited; radial head replacement in complex elbow reconstruction; stem cells in early fracture haematoma; heterotrophic ossification in forearms; and Boston in perspective

We assessed the management of 11 neglected developmental dislocated hips in terms of shape of the acetabulum and femoral head pre-operatively and the level of the position of the reduction immediately post-operatively. We compared it with medium term clinical and radiological results. The shape of the acetabulum and the femoral head can be determined in two planes doing CT or MR of the pelvis. The studies were done to determine the development of the acetabulum and the anatomical fit of the femoral head in the acetabulum. Radius of curvature in the axial and coronal planes was determined of the acetabulum and the femoral head. MR spin echo specification for visualization of the cartilage bone was used. Post-operative radiological namely CT when still in spika, and Shenton’s line and central location of the hip in the direction of the triradiate were subsequently assessed. Radius of curvature was determined in 6 cases. It varied according to age, but for the older patients the acetabulum was 5mm smaller on average on the coronal views. Eight hips were treated with open reduction. Postoperatively one hip gradually subluxed and dislocated eventually. The hips that remained reduced were initially inferiorly located with an irregular Shenton’s line. Three were treated conservatively with pelvic support osteotomies and planned bone lengthening procedures. Shape of the femoral head and acetabulum is the most important determining factor in open reduction of neglected DDH. Axial plane MR radius of curvature is not necessarily a true reflection of the shape of the acetabulum. MR coronal views with cartilage enhancement are necessary in assessing the shape of the acetabulum. The inferior position of the reduced hip can be ascribed to the conical shape of the acetabulum and is associated with a maintained reduction

Introduction. Arthritis of the glenohumeral joint is usually associated with erosion and flattening of the articular surfaces. The aim of this study was to evaluate the influence of the articular flattening on the joint reaction forces and the humeral head translations during abduction and rotation. Method. Analysis was conducted with a 3D finite element model of the shoulder, including the scapula, the humerus and 6 muscles: middle, anterior and posterior deltoid, supraspinatus, subscapularis, and infraspinatus. Both the glenoid and humeral head were eroded to artificially reproduce the flattening of an arthritic joint. Two situations were studied:. 1) an intact joint with a radius of curvature of 24mm for the humeral head and 26mm for the glenoid;. 2) an eroded joint with a radius of curvature of 40mm for the humeral head and 42mm for the glenoid. Movements of external rotation (0–45°) and abduction (0–150°) were performed by muscles’ activation. Contact forces caused by muscles wrapping on bony surfaces were accounted for. Joints forces, glenohumeral contact point locations and humeral head translations were calculated for the intact and eroded joint. Results: For the eroded joint, articular forces were up to seven times higher during rotation and five times higher during abduction. For the intact joint, the glenohumeral contact point and humeral head remained centred. On the other hand, for the eroded joint, eccentric contact points with large antero-posterior and supero-inferior humeral head translations were observed. Animated views showed that this fact was clearly related to the rocking-horse effect. Conclusions: This study showed that flattening of the glenohumeral joint due to osteoarthritis increases dramatically the articular forces and humeral head translations. This phenomenon is by itself responsible for progression of the joint’s erosion and flattening and acts as a vicious cycle. It also partly explains the reduced range of motion observed clinically. Accordingly, to limit the risks of rocking-horse effect after shoulder arthroplasty, the joint’s reconstruction should restore a natural articular radius of curvature, with a centre of rotation in the middle of the humeral head

1. Introduction. Such a Total Knee Arthroplasty (TKA) that is capable of making high knee flexion has been long awaited for the Asian and Muslim people. Our research group has developed the TKA possible to attain complete deep knee flexion such as seiza sitting. Yet as seiza is peculiar to the Japanese, other strategies will be necessary for our TKA to be on the overseas market. Still it is impractical to prepare many kinds of modifications of our TKA to meet various demands from every country/region. To this end, we contrived a way to modularize the post-cum alignment of our TKA in order to facilitate the following three activities containing high knee flexion: praying for the Muslim, gardening or golfing for the Westerner, sedentary siting on a floor for the Asian. We performed simulation and experiment, such as a mathematical model analysis, FEM analysis and a cadaveric study, thereby determining the optimal combination of moduli for the above activities respectively. 2. Methods. We modularized the post-cum alignment by three parameters in three levels respectively (Fig.1). The shape of the post's sagittal section and the total shape of cum were unchanged. The three parameters for modularization were the post location which was shifted anterior and posterior by 5 mm from the neutral position, the post inclination which was inclined forward and backward by 5° from the vertical, and the radius of curvature of the post's horizontal section which was increased and decreased by 2 mm from the original value. It is crucial to decrease contact stress between the post and cum during praying for the Muslim and during gardening or golfing for the Westerner, which would be realized by choosing the optimal location and inclination of post when kneeling for the Muslim and when squatting for the Westerner respectively (Fig.2). As for the Asian, it is desirable for them to perform various kinds of sedentary sittings on a floor without difficulties, which would be facilitated by choosing the optimal radius of curvature value to increase range of rotation when the knee is in high-flexion (Fig.2). First we performed a mathematical model analysis to introduce the kinetic data during sit-to-stand activities. Then by using the above kinetic data we performed the FEM analysis to determine the contact stress between the post and cum during praying, gardening or golfing. Finally we carried out the cadaveric study to determine the range of rotation at high flexion of the knee. 3. Results and Discussion. The results of FEM analysis demonstrated that the best modular set for the activities for Muslim and Westerners were so that the post location should be shifted by 5 mm and the post inclination should not be applied (Fig.3). The results of cadaveric study demonstrated that the radius of horizontal curvature should be increased by 2mm so as to increase the range of rotation especially when the knee is in high flexion. The subjects for our future study are to verify the validities of the above results through our simulator tests

Introduction:. This study evaluates the impact of radii-related differences in posterior cruciate ligament retaining (PCR) primary total knee arthroplasty (TKA) prosthetic designs on knee biomechanics during level walking 1-year after surgery. The multi-radius (MR) design creates at least two instantaneous flexion axes by changing the radius of curvature of the femoral component throughout the arc of knee motion. The femoral component of the single-radius (SR) design has only one radius and therefore a fixed axis. Methods:. Subjects scheduled for computer-navigated TKA (n = 37: SR n = 20 [9M, 11F], MR n = 17 [8M, 9F]; 69.8 ± 7.1 years, 87.6 ± 20.8 kg, 1.68 ± 0.09 m), and demographic-matched controls without knee pathology n = 23 [13M, 10F], provided informed consent under the Banner IRB (Sun Health panel). All surgical subjects received similar pre-, peri-, and post-operative care under the direction of three surgeons from a single orthopedic practice. Position and force data were collected using 28 reflective markers (modified Helen Hayes [Kadaba et al 1990]) tracked by ten digital IR cameras (120 Hz) (Motion Analysis Corp., Santa Rosa, CA) and four force platforms (1200 Hz) (AMTI, Watertown, MA) embedded in an 8m walkway. Data were recorded and smoothed (Butterworth filter, 6 Hz) using EVaRT 5.0.4 software (Motion Analysis Corp.). Gait cycle parameters were calculated using the ‘Functional Hip Center’ and ‘Original Knee Axis’ models in Orthotrak 6.6.1 (Motion Analysis Corp.). Data from each group were height and weight normalized and ensemble averaged by affected limb (right limb for controls) using custom code written in Labview (National Instruments Corp, Austin, TX). Descriptive statistics for the maximum and minimum knee kinematic, kinetic, and temporal spatial values in the stance and swing phases of the gait cycle were generated for each group. Between-group comparisons were made using an ANOVA with post hoc testing as appropriate (SPSS 14.0 (SPSS Inc, Chicago, IL)). Results:. Total range of motion was similar between surgical groups but MR was 5° more extended than SR throughout stance (p < 0.05) (Figure 1). MR knee power absorption (Figure 2) and medial knee force were less than controls (p < 0.05). SR and controls were similar for several knee parameters (p > 0.05) (Table 1). Discussion:. The performance of the SR design was more control-like in several parameters at one year. A shifting radius of curvature, which alters patella-femoral moment arm geometry and resulting quadriceps force [D'Lima et al 2001], may contribute to reduced knee power in the MR group. The fluctuating radius of curvature may also generate collateral ligament laxity with increasing flexion angles [Wang et al 2005, Whiteside et al 1989] contributing to the observed deficit in medial knee forces. The increased knee extension angles in the MR group are indicative of a stabilizing adaptation throughout the range of motion. While previous biomechanics studies following TKA have revealed few to no significant differences in gait performance due to implant design, the use of computer navigation and standard order sets, which control for alignment and other confounding variables, may generate tighter data sets that reveal differences masked by variation within surgical groups rather than between them

Introduction: Accurate recovery of humeral head geometry in shoulder arthroplasty is an important requirement for a good functional outcome. Despite this, spherical prosthetic components are implanted when the total proximal humerus is described as ovoid. 1. However, 60 to 80 % of the head is spherical. 1. If, in the normal glenohumeral joint, only the spherical portion is in contact with the glenoid then recovery of normal mechanics is likely with a spherical prosthetic component. Contact patterns have been examined ex vivo. 2. under static conditions but do not reflect the likely in vivo contact pattern under dynamic loading and have not been correlated to changes in sphericity of the articular surface. A recent study of the distal femur found that thickness of normal articular cartilage is positively correlated with loading. 3. and, thus, contact. The objective of this study was to determine the feasibility of using a surface laser scanner to determine cartilage thickness and, therefore, likely contact area and to correlate changes in thickness to changes in sphericity of the articular surface. Methods: A cadaveric arm without bony deformity or evidence of rotator cuff disease was dissected free of soft tissue and mounted on a rigid block within the frame of a surface laser scanner (Kestrel3D Ltd., UK). The articular surface of the humerus was scanned at a resolution of 200 μm. The cartilage was then dissolved away and the humerus re-scanned. The x,y,z coordinate data of the re-scanned bone were used to match the sub-chondral bone with the cartilage from the previous scan using Pointstream™ software (Kestrel3D Ltd., UK). The cloud point data for the cartilage and bony surfaces were exported into modelling software (McNeal and Assoc., Seattle, WA) and the surface area of the head divided into ten equal sections. For each slice of both the cartilage and bony surface, the radius of curvature was calculated using a least square fit optimisation technique. 4. The differences in radius of curvature between the cartilage surface and subchondral bone surface were used to calculate the cartilage thickness for each slice. The standard deviation from the radius of curvature was used to calculate the degree of deviation from sphericity. Results: For the first 60 % of the surface area, the deviation from sphericity was 0.5% of the radius with a cartilage thickness of 0.74 mm. The deviation from sphericity and cartilage thickness for 100% of the articular surface was > 1% and 0.63 mm, respectively. Conclusions: The experiment proved that the surface laser scanner can be used to elucidate the relationship between contact patterns and articular curvature of the proximal humerus. The changes in sphericity concur with results from previous studies. 1. Assuming cartilage thickness correlates to contact patterns at the normal glenohumeral joint, the change in cartilage thickness suggests that contact may occur only at the spherical portion of the head. Knowledge of this relationship may aid in future prosthetic design considerations or in modification of the osteotomy technique. To further support these findings, a 50μm laser scanner is being developed and will be used on a larger sample size

Several studies have suggested that, in TKR, gender specific-prostheses are needed to accommodate anatomic differences between males and females. This study was performed to examine whether gender is a factor contributing to the variability of the size, shape and orientation of the patellofemoral sulcus. 3D computer models of the femur were reconstructed from CT scans of 20 male and 20 female femora. The patellofemoral groove was quantified by measuring landmarks at 10 degree increments around the epicondylar axis. The orientation of the groove was defined by the tracking path generated by a sphere moving from the top of the groove to the intercondylar notch. To assess the influence of gender on the shape of the distal femur, all morphologic parameters were normalized for differences in bone size. Overall, the distal femur was 15% larger in males compared to females. The male condyles were 4% wider than the female for constant AP depth (p=0.13). When normalized for bone size, there was no gender difference in most patello-femoral dimensions, including the length, width, angle or tilt of the sulcus. Female femora had a less prominent medial anterior ridge (p=0.07), and a larger normalized radius of curvature of the tracking path (p=0.03). In addition, the orientation of the sulcus differed by 1–2 degrees in both the coronal and axial planes. Overall, gender explained 4.7% of the anatomic variation of the parameters examined, varying from 0 to 15.9%. The size, shape and orientation of the patello-femoral groove are highly variable. While the patello-femoral morphology of male and female femora are very similar, some of the anatomic variability is related to gender, particularly the prominence of the medial ridge and the sulcus radius of curvature. The biomechanical and clinical significance of these differences after TKA have yet to be determined

Purpose. There have been a number of described techniques for sizing the diameter of radial head implants. All of these techniques, however, are dependent on measurements of the excised native radial head. When accurate sizing is not possible due to extensive comminution or due to a previous radial head excision, it has been postulated that the proximal radioulnar joint (PRUJ) may be used as an intraoperative landmark for correct sizing. The purpose of this study was to: 1) determine if the PRUJ could be used as a reliable landmark for radial head implant diameter sizing when the native radial head in unavailable, and (2) determine the reliability of measurements of the excised radial head. Method. Twenty-seven fresh-frozen denuded ulnae and their corresponding radial heads (18 males, 9 females) were examined. The maximum diameter (MaxD), minimum diameter (MinD) and dish diameter (DD) of the radial heads were measured twice, 3–5 weeks apart, using digital calipers. Two fellowship-trained upper extremity surgeons, an upper extremity fellow and a senior orthopedic resident were then asked to independently select a radial head implant diameter based on the congruency of the radius of curvature of the PRUJ to that of the radial head trial implants. The examiners were blinded to the native radial head dimensions. This selection was repeated 3–5 weeks later by two of the investigators. Correlation between radial head measurements and radial head implant diameter sizes was assessed using Pearsons correlation coefficient (PCC) and inter and intra-observer reliability were assessed using intra-class correlation coefficient (ICC). Results. There was a positive correlation between each of the radial head measurements (MaxD, MinD and DD) and the selected radial head implant diameters (PCC of 0.56, 0.59 and 0.51 respectively; p<0.01). Measuring the MaxD, MinD and DD of the radial head showed excellent inter-observer reliability (ICC of 0.99, 1.00 and 0.82 respectively) and excellent intra-observer reliability (ICC of 0.99, 0.98 and 0.75 respectively). The PRUJ sizing method used to determine the diameter of the radial head implant showed poor inter-observer reliability with an ICC of 0.34 but good intra-observer reliability (ICC = 0.76). Conclusion. Measurements of the diameter of the excised radial head showed excellent intra and inter-observer reliability suggesting that the excised radial head, when available, should be used to select the radial head implant diameter. The inter-observer reliability of using the PRUJ for sizing the diameter of radial head implants was poor, indicating that this method is an unreliable technique for radial head implant diameter sizing. However, the high intra-observer reliability of the PRUJ method indicates that an observer tends to make the same size estimation, even weeks apart. This study suggests that the PRUJ radius of curvature may be different than that of the radial head. Further studies are needed to verify this hypothesis

Notching of the anterior femoral cortex during total knee arthroplasty is thought to be a possible risk factor for subsequent periprosthetic femoral fracture. Understanding the stress pattern caused by notching may help the orthopedic surgeon reduce the risk of fracture. A validated, three dimensional, finite element model of the femur using gait loads has been used to analyze the stress concentrations caused by anterior femoral cortex notching. Three factors that increase these stresses were identified. The notch depth, radius of curvature, and its proximity to the end of the femoral prosthesis influence the state of stress in the surrounding bone. The purpose of this study was to characterize the stress concentration caused by anterior femoral notching during total knee replacement (TKR) in order to determine when a patient is at risk for a periprosthetic fracture of the femur. We concluded that notches greater than 3 mm with sharp corners located directly at the proximal end of the femoral implant produced the highest stress concentrations and may lead to a significant risk of periprosthetic femur fracture. One complication that can occur during TKR is notching of the anterior femoral cortex which results in a stress concentration. It is important to characterize this stress riser in order to determine when a stemmed femoral component should be used to minimize the risk of fracture. Three factors that affected the stress concentration were identified. First, increasing the notch depth lead to significant increased stress concentrations. When the depth was greater than 3 mm, local stresses increased markedly. Second, the radius of curvature was found to be inversely related to stress concentration. As the radius decreased, the local stress increased. Third, the proximity of the notch to the prostheses affected the stress concentration. Notches that were 1 mm proximal to the implant resulted in much larger stresses than those that were 10 mm away. A validated, three dimensional finite element model of a femur subjected to a gait loading pattern was used to characterize the stress concentration caused by anterior femoral notching. The results compared well to previous work reported in the literature

Notching of the anterior femoral cortex during total knee arthroplasty is thought to be a possible risk factor for subsequent periprosthetic femoral fracture. Understanding the stress pattern caused by notching may help the orthopedic surgeon reduce the risk of fracture. A validated, three dimensional, finite element model of the femur using gait loads has been used to analyze the stress concentrations caused by anterior femoral cortex notching. Three factors that increase these stresses were identified. The notch depth, radius of curvature, and its proximity to the end of the femoral prosthesis influence the state of stress in the surrounding bone. The purpose of this study was to characterize the stress concentration caused by anterior femoral notching during total knee replacement (TKR) in order to determine when a patient is at risk for a periprosthetic fracture of the femur. We concluded that notches greater than 3 mm with sharp corners located directly at the proximal end of the femoral implant produced the highest stress concentrations and may lead to a significant risk of periprosthetic femur fracture. One complication that can occur during TKR is notching of the anterior femoral cortex which results in a stress concentration. It is important to characterize this stress riser in order to determine when a stemmed femoral component should be used to minimize the risk of fracture. Three factors that affected the stress concentration were identified. First, increasing the notch depth lead to significant increased stress concentrations. When the depth was greater than 3 mm, local stresses increased markedly. Second, the radius of curvature was found to be inversely related to stress concentration. As the radius decreased, the local stress increased. Third, the proximity of the notch to the prostheses affected the stress concentration. Notches that were 1 mm proximal to the implant resulted in much larger stresses than those that were 10 mm away. A validated, three dimensional finite element model of a femur subjected to a gait loading pattern was used to characterize the stress concentration caused by anterior femoral notching. The results compared well to previous work reported in the literature

Patients undergoing revision surgery of a primary total hip arthroplasty often exhibit bone loss and poor bone quality, which make achieving stable fixation and osseointegration challenging. Implant components coated in porous metals are used clinically to improve mechanical stability and encourage bone in-growth. We compared ultra-porous titanium coatings, known commercially as Gription and Porocoat, in an intra-articular model by press-fitting coated cylindrical implants into ovine femoral condyles and evaluating bone in-growth and fixation strength 4, 8 and 16 weeks post-operatively. Bilateral surgery using a mini-arthrotomy approach was performed on twenty-four Dorset-Rideau Arcott rams (3.4 ± 0.8 years old, 84.8 ± 9.3 kg) with Institutional Animal Care Committee approval in accordance with the Canadian Council on Animal Care. Cylindrical implants, 6.2 mm in diameter by 10 mm in length with surface radius of curvature of 35 mm, were composed of a titanium substrate coated in either Porocoat or Gription and press-fit into 6 mm diameter recipient holes in the weight-bearing regions of the medial (MFC) and lateral (LFC) femoral condyles. Each sheep received 4 implants; two Gription in one stifle (knee) and two Porocoat in the contralateral joint. Biomechanical push-out tests (Instron ElectroPuls E10000) were performed on LFCs, where implants were pushed out relative to the condyle at a rate of 2 mm/min. Force and displacement data were used to calculate force and displacement at failure, stiffness, energy, stress, strain, elastic modulus, and toughness. MFCs were fixed in 70% ethanol, processed undecalcified, and polished sections, approximately 70 µm thick (Exakt Micro Grinding system) were carbon-coated. Backscattered electron images were collected on a scanning electron microscope (Hitachi SU3500) at 5 kV and working distance of 5 mm. Bone in-growth within the porous coating was quantified using software (ImageJ). Statistical comparisons were made using a two-way ANOVA and Fisher's LSD post-hoc test (Statistica v.8). Biomechanical evaluation of the bone-implant interface revealed that by 16 weeks, Gription-coated implants exhibited higher force (2455±1362 N vs. 1002±1466 N, p=0.046) and stress (12.60±6.99 MPa vs. 5.14±7.53 MPa, p=0.046) at failure, and trended towards higher stiffness (11510±7645 N/mm vs. 5010±8374 N/mm, p=.061) and modulus of elasticity (591±392 MPa vs. 256±431 MPa, p=0.61). Similarly, by 16 weeks, bone in-growth in Gription-coated implants was approximately double that measured in Porocoat (6.73±3.86 % vs. 3.22±1.52 %, p=0.045). No statistically significant differences were detected at either 4 nor 8 weeks, however, qualitative observations of the exposed bone-implant interface, made following push-out testing, showed more bony material consistently adhered to Gription compared to Porocoat at all three time points. High variability is attributed to implant placement, resulting from the small visual window afforded during surgery, unique curvatures of the condyles, and presence of the extensor digitorum longus tendon which limited access to the LFC. Ultra-porous titanium coatings, know commercially as Gription and Porocoat, were compared for the first time in a challenging intra-articular ovine model. Gription provided superior fixation strength and bone in-growth, suggesting it may be beneficial in hip replacement surgeries where bone stock quality and quantity may be compromised

For many years, it has been taught that the human knee is a ‘hinge’ joint and that the motion of the knee is controlled by a ‘four-bar link’. This classic view of the motions of the knee suggests that there is a prescribed path for the knee as it proceeds from extension to flexion and flexion to extension. This prescribed motion includes ‘rollback’, a term used for the progressive posterior displacement of the femur on the tibia as the knee moves from extension to flexion,. Most of the total knee prostheses available today have been designed to permit the movements that are required by this model of knee motion. The design features necessary to permit this motion are a lack of constraint between the tibial and femoral components, and a ‘J’ curve of the posterior part of the femoral component such that the radius of curvature is smaller on the posterior portion of the component than on the distal part. Studies of the anatomy of the knee date back to the 1800s, before radiological studies were possible. Radiological evidence does not support the four-bar link and rollback theories or indicate that a ‘J’ curve is necessary. Rather, radiographs suggest that the knee is more of a ball-in-socket joint on the medial side with little or no rollback in normal function. Three-dimensional studies of the moving human knee both in vitro and in vivo also demonstrated that the knee joint moves as a ball-in-socket joint on the medial side, and that the lateral side displaces posteriorly or anteriorly as necessary to accommodate the rotational position of the tibia relative to the femur. These kinematic findings have led to the design of a pros-thesis that mimics the normal knee. The femoral prosthesis has a single radius of curvature to each condyle both in the sagittal and coronal planes. The mating tibial component has an exactly conforming geometry on the medial side leading to ball-in-socket type of kinematics. The lateral side of the tibial component allows anterior or posterior displacement of the femur, mining the normal changes that take place with internal and external rotation. Initial clinical results total knee arthroplasty procedures performed with this prosthesis are just passing the three-year follow-up interval. There have been no reports of catastrophic problems, and surgeons have been pleased with the stability, the rapidity with which function is regained, and the excellent range of motion following arthroplasty. Patients who have a more traditional total knee arthroplasty in one knee and the medial pivot prosthesis in the other prefer the medial pivot because of the feeling of stability

Joint hemiarthroplasty replaces one side of a synovial joint and is a viable alternative to total joint arthroplasty when one side of the joint remains healthy. Most hemiarthroplasty implants used in current clinical practice are made from stiff materials such as cobalt chrome or ceramic. The substitution of one side of a soft cartilage-on-cartilage articulation with a rigid implant often leads to damage of the opposing articular cartilage due to the resulting reductions in contact area and increases in cartilage stress. The improvement of post-operative hemiarthroplasty articular contact mechanics is of importance in advancing the performance and longevity of hemiarthroplasty. The purpose of the present study was to investigate the effect of hemiarthroplasty surface compliance on early in-vitro cartilage wear and joint contact mechanics. Cartilage wear tests were conducted using a six-station pin-on-plate apparatus. Pins were manufactured to have a hemispherical radius of curvature of 4.7 mm using either Bionate (DSM Biomedical) having varying compliances (80A [E=20MPa], 55D [E=35MPa], 75D [E=222MPa], n=6 for each), or ceramic (E=310GPa, n=5). Cartilage plugs were cored from fresh unfrozen bovine knee joints using a 20 mm hole saw and mounted in lubricant-containing chambers, with alpha calf serum diluted with phosphate buffer solution to a protein concentration of 17 g/L. The pins were loaded to 30N and given a stroke length of 10 mm for a total of 50,000 cycles at 1.2 Hz. Volumetric cartilage wear was assessed by comparing three-dimensional cartilage scans before and during wear testing. A two-way ANOVA was used for statistical analysis. To assess hemiarthroplasty joint contact mechanics, 3D finite element modelling (ABAQUS v6.12) was used to replicate the wear testing conditions. Cartilage was modeled using neo-Hookean hyper-elastic material properties. Contact area and peak contact stress were estimated. The more compliant Bionate 80A and 55D pins produced significantly less volumetric cartilage wear compared with the less compliant Bionate 75D and ceramic pins (p 0.05). In terms of joint contact mechanics, the more compliant materials (Bionate 80A and 55D) had significantly lower maximum contact stress levels compared to the less compliant Bionate 75D and ceramic pins (p < 0 .05). The results of this study show a relationship between hemiarthroplasty implant surface compliance and early in vitro cartilage wear, where the more compliant surfaces produced significantly lower amounts of cartilage wear. The results of the joint contact mechanics analysis showed that the more compliant hemiarthroplasty materials produced lower maximum cartilage contact stresses than the less compliant materials, likely related to the differences in wear observed. More compliant hemiarthroplasty surfaces may have the potential to improve post-operative cartilage contact mechanics by increasing the implant-cartilage contact area while reducing peak contact stress at the implant-cartilage interface, however, such materials must be resistant to surface fatigue and longer-term cartilage wear/damage must be assessed

Introduction. Despite the positive outcomes in shoulder joint replacements in the last two decades, polyethylene wear debris in metal-on-polyethylene artificial shoulder joints is well-known as a limitation in the long-term survival of shoulder arthroplasties systems. Consequently, there is an interest in the use of novel materials as an alternative to hard bearing surfaces such as pyrolytic carbon layer (PyroCarbon). Materials and Methods. In the present study, the unique Newcastle Shoulder Wear Simulator was used (Smith et al., 2015; Smith et al., 2016) to evaluate the wear behavior of four commercially available PyroCarbon humeral heads 43 mm diameter, articulating against conventional ultra-high molecular weight polyethylene (UHMWPE) glenoid inserts with a radius of curvature of 17.5 mm to form an anatomic total shoulder arthroplasty. A physiological combined cycled “Repeat-motion-load” (RML) (Ramirez-Martinez et al., 2019) obtained from the typical activities of daily life of patients with shoulder implants was applied as a simulator input. A fifth sample of the same size and design was used as a soak control and subjected to dynamic loading without motion during the wear test. The mean volumetric wear rate of PyroCarbon-on-polyethylene was evaluated over 5 million cycles gravimetrically and calculated on the basis of linear regression, as well as the change in surface roughness (S. a. ) of the components using a non-contacting white light profilometer throughout the test. Results. The gravimetric analysis showed a mean volumetric wear rate and standard deviation of 19.3±9.5 mm. 3. /million cycles for the UHMWPE glenoid inserts, whereas PyroCarbon humeral head counterparts did not exhibit a loss in mass throughout the test. The roughness values of the UHMWPE glenoid inserts decreased (P < .001), changing from 296±28 nm to 32±8 nm at the end of the test. In contrast, the PyroCarbon humeral heads did not show a significant change (P = .855) over the 5 million cycles; remained in the same range (21±2 nm to 20±10 nm) with no evidence of wear damage on the surface. Conclusions. This is the first in-vitro shoulder simulator study of a PyroCarbon on UHMWPE articulation. Wear rates were similar to that found to well-proven metal on UHMWPE shoulder arthroplasties. While it was interesting to see that the PyroCarbon did not roughen over the test duration, the lack of an appreciable reduction in wear of the UHMWPE component when articulated with an expensive and complex to manufacture PyroCarbon component likely means there is little clinical cost-benefit in the use of a PyroCarbon on UHMWPE shoulder implant. Declaration of competing interest. Prof. Ian A. Trail received some royalties and research support from Wright Medical Group N.V. None of the other authors, their immediate families, and any research foundation with which they are affiliated did not receive any financial payments or other benefits from any commercial entity related to the subject of this article. For any figures or tables, please contact authors directly

Prior implant designs have relied on a four-bar link theory and featured J-curve femoral components intended to recreate femoral rollback of the native knee, but this design could lead to anterior femoral sliding or paradoxical motion. Recent kinematic analyses of the native human knee have shown the medial compartment to be more stable to anteroposterior translation than the lateral, resulting in a “medial pivot” motion as the knee flexes. “Medial pivot” designs in total knee arthroplasty were introduced in the 1990s to attempt to re-create this motion. They consist of an asymmetric tibial insert with a highly congruent medial compartment and less conforming lateral compartment. The femoral component has a single radius of curvature and a high degree of conformity. In vivo fluoroscopic studies have shown medial pivot designs to be successful in achieving its intended motion, while other cruciate-retaining designs had a higher incidence of paradoxical anterior translation and lateral condylar lift-off. Furthermore, numerous investigations have shown medial pivot designs to have excellent outcomes and survivorship at up to 10 years post-operatively. However, the contention in this debate that medial pivot designs avoid the need for ligament balancing is incorrect. Appropriate ligament balancing remains a crucial aspect of any successful total knee arthroplasty and is no less important based on the implant design utilised. In the Methods section of all prior reports using a medial pivot design, the authors have noted that appropriate ligament balancing was obtained both in flexion and extension consistent with the recommended technique with other primary TKA implant designs. From a kinematic standpoint, this makes absolute sense. If a patient has a valgus imbalance with loose medial structures, then as the knee is brought into flexion the femur will not maintain congruency and contact with the conforming tibial surface – thus the medial pivot motion will be lost. Thus, balancing remains critical. Lastly, although not the focal point of this debate, whether re-creation of a medial pivot motion in total knee arthroplasty actually improves patient outcomes remains an area of debate. A recent investigation by Warth and Meneghini, et al. demonstrated that re-creation of a medial-pivot pattern intra-operatively did not correlate with patient-reported outcomes at 1-year post-operatively. Thus, although the concept of a medial pivot design has merit, whether this will consistently improve outcomes and patient satisfaction remains to be seen

Humeral head size is defined by the radius of curvature and the thickness of the articular segment. This ratio of radius to thickness is within a narrow range with an average of 0.71. The articular surface of the normal humeral head measured within the AP plane is defined by three landmarks on the non-articular surface of the proximal humerus. The perfect circle concept can be applied for assessment of the anatomic reconstruction of the post-operative x-rays and more importantly can be used intra-operatively as a guide when choosing the proper prosthetic humeral head component. The humeral head is an elliptical shape with its AP dimension being approximately 2 mm less than the SI dimension. This shape contributes to the roll and translation of the normal shoulder but is not replicated by the spherical shape of the prosthetic humeral head. The glenoid vault has a consistent 3D shape and use of the vault model within 3D planning software can define the patient's pre-morbid anatomy, specifically the location of the joint line and patient specific version and inclination. Use of this tool can assist the surgeon in defining the optimal implant and its location. In patients with little or no bone loss, a symmetric glenoid implant is often ideal for resurfacing. When there is asymmetric bone loss, often seen posteriorly with osteoarthritis, an asymmetric posteriorly augmented component can improve the ability to correct the deformity while maintaining the native joint line. It is suggested that these augmented implants in selected patients will help restore and maintain humeral alignment and lessen the risk for residual posterior humeral head subluxation and eccentric loading of the glenoid component