In acute
Acute
Acute
Aims: to present a new classification of
Acute osteomyelitis and septic arthritis are uncommon diseases in childhood that affect previously healthy children. A high index of suspicion, early diagnosis, initiation of appropriate antibiotic treatment and surgical intervention are essential for a good outcome. The aim of our study was to evaluate our approach, clinical signs and the outcome of the diseases. We retrospectively analyzed clinical, laboratory and microbiologic data in children hospitalized for acute
Acute
Acute
Introduction and Aims: This disease has an insidious onset and develops as a result of increased host resistance and decreased bacterial virulence. The aim of this paper is to describe the spectrum of primary subacute forms of
Purpose of study. The aim of this study was to identify the incidence of Gram negative bacterial vertebral osteomyelitis (VO) within our unit during a 3-year study period and evaluate if this corresponds to published evidence that the occurrence is increasing. Methods. Between May 2007 and May 2010, all patients, over the age of 18 years, suffering from Gram-negative VO were identified and their microbiological diagnoses were evaluated. All patients were treated within a large tertiary spinal surgery unit in Leeds. Results. This study identified 79 patients with
Pyogenic
Background: Pyogenic
This is an ongoing retrospective study of 35 children treated from 1986 to 2001 for chronic osteomyelitis following acute
Aim. We report our ten year experience of primary
Melioidosis is a significant public health problem in endemic regions such as India. Lack of awareness, predominant empiric antibiotic use reducing culture yields, morphotypic variability of cultures and frequent misidentification by automated blood culture systems, pose myriad challenges in diagnosis and treatment. Through this series, we present our experience of Hematogenous Osteomyelitis with This was a single centre, retrospective, observational study performed at a tertiary case hospital in Mumbai, India from June 2011 to June 2021.Aim
Method
The gold standard treatment for late acute hematogenous (LAH) periprosthetic joint infection (PJI) is surgical debridement, antibiotics and implant retention (DAIR). However, this strategy is still controversial in the case of total knee arthroplasty (TKA) as some studies report a higher failure rate. The aim of the present study is to report the functional outcomes and cure rate of LAH PJI following TKA treated by means of DAIR at a long-term follow-up. A consecutive prospective cohort consisting of 2,498 TKA procedures was followed for a minimum of 10 years (implanted between 2005 and 2009). The diagnosis of PJI and classification into LAH was done in accordance with the Zimmerli criteria (NEJM 2004). The primary outcome was the failure rate, defined as death before the end of antibiotic treatment, a further surgical intervention for treatment of infection was needed and life-long antibiotic treatment or chronic infection. The Knee Society Score (KSS) was used to evaluate clinical outcomes. Surgical management, antibiotic treatment, the source of infection (primary focus) and the microorganisms isolated were also assessed.Aim
Method
Acute hematogenous periprosthetic joint infection (AHI) is a diagnosis on the rise. The management is challenging and the optimum treatment is not clearly defined. The purpose of this study was to evaluate the characteristics of AHI, and to study risk factors affecting treatment outcome. We retrospectively analysed 44 consecutive episodes with AHI in a total hip or knee arthroplasty beween 2013 and 2020 at a single center. AHI was defined as abrupt symptoms of infection ≥ 3 months after implantation in an otherwise well functioning arthroplasty. We used the Delphi criteria to define treatment failure with a minimum of 1-year follow-up.Aim
Methods
The incidence of hematogenous periprosthetic joint infections (hPJI) is unknown and the cases probably largely underreported. Unrecognized and untreated primary infectious foci may cause continuous bacteremia, further spread of microorganisms and thus treatment failure or relapse of infection. This study aimed at improving knowledge about primary foci and microbiological characteristics of this entity to establish preventive measures and improve diagnostic and therapeutic strategies to counteract hPJI. We retrospectively analysed all consecutive patients with hPJI, who were treated at our institution from January 2010 until December 2016. Diagnosis of PJI was established if 1 of the following criteria applied:(i) macroscopic purulence, (ii) presence of sinus tract, (iii) positive cytology of joint aspirate (>2000 leukocytes/μl or >70% granulocytes), (iv) significant microbial growth in synovial fluid, periprosthetic tissue or sonication culture of retrieved prosthesis components, (v) positive histopathology. PJI was classified as hematogenous if the following criteria were fulfilled additionally: (1) onset of symptoms more than 1 month after arthroplasty AND (2) i) isolation of the same organism in blood cultures OR ii) evidence of a distant infectious focus consistent with the pathogen.Aim
Method