Aseptic loosening is one of the highest causes for revision in total knee arthroplasty (TKA). With growing interest in anatomically aligned (AA) TKA, it is important to understand if this surgical technique affects cemented tibial fixation any differently than mechanical alignment (MA). Previous studies have shown that lipid/marrow infiltration (LMI) during implantation may significantly reduce fixation of tibial implants to bone analogs [1]. This study aims to investigate the effect of surgical alignment on fixation failure load after physiological loading. Alignment specific physiological loading was determined using telemetric tibial implant data from Orthoload [2] and applying it to a validated finite element lower limb model developed by the University of Denver [3]. Two high demand activities were selected for the loading section of this study: step down (SD) and deep knee bend (DKB). Using the lower limb model, hip and ankle external boundary conditions were applied to the ATTUNE® knee system for both MA and AA techniques. The 6 degree of freedom kinetics and kinematics for each activity were then extracted from the model for each alignment type. Mechanical alignment (MA) was considered to be neutral alignment (0° Hip Knee Ankle Angle (HKA), 0° Joint Line (JL)) and AA was chosen to be 3° varus HKA, 5° JL. It is important not to exceed the limits of safety when using AA as such it is noted that DePuy Synthes recommends staying within 3º varus HKA and 3º JL. The use of 5º JL was used in this study to account for surgical variation [Depuy-Synthes surgical technique DSUS/JRC/0617/2179]. Following a similar method described by Maag et al [1] ATTUNE tibial implants were cemented into a bone analog with 2 mL of bone marrow in the distal cavity and an additional reservoir of lipid adjacent to the posterior edge of the implant. Tibial implant constructs were then subjected to intra-operative ROM/stability evaluation, followed by a hyperextension activity until 15 minutes of cement curing time, and finally 3 additional ROM/stability evaluations were performed using an AMTI VIVO simulator. The alignment specific loading parameters were then applied to the tibial implants using an AMTI VIVO simulator. Each sample was subjected to 50,000 DKB cycles and 120,000 SD cycles at 0.8 Hz in series; approximating 2 years of physiological activity. After physiological loading the samples were tested for fixation failure load by axial pull off.Introduction
Methods
Patella implant research is often overlooked despite its importance as the third compartment in a total knee replacement. Wear and fracture of resurfaced patellae can lead to implant failure and revision surgeries. New simulation techniques have been developed to analyze the performance of patella designs as they interact with the trochlear groove in total knee components, and clinical validation is sought to ensure that these simulations are appropriate. The objective of this work was to subject several patellar designs to patient-derived deep knee bend (DKB) inputs on a 6 degree of freedom (DOF) simulator and compare the resultant wear scars to clinical retrievals. Previously reported DKB profiles were developed based on Introduction
Materials and Methods
Aseptic loosening of total knee replacements is a leading cause for revision. It is known that micromotion has an influence on the loosening of cemented implants though it is not yet well understood what the effect of repeated physiological loading has on the micromotion between implants and cement mantle. This study aims to investigate effect of physiological loading on the stability of tibial implants previously subjected to simulated intra-operative lipid/marrow infiltration. Three commercially available fixed bearing tibial implant designs were investigated in this study: ATTUNE®, PFC SIGMA® CoCr, ATTUNE® S+. The implant designs were first prepared using a LMI implantation process. Following the method described by Maag et al tibial implants were cemented in a bone analog with 2 mL of bone marrow in the distal cavity and an additional reservoir of lipid adjacent to the posterior edge of the implant. The samples were subjected to intra- operative range of motion (ROM)/stability evaluation using an AMTI VIVO simulator, then a hyperextension activity until 15 minutes of cement cure time, and finally 3 additional ROM/stability evaluations were performed. Implant specific physiological loading was determined using telemetric tibial implant data from Orthoload and applying it to a validated FE lower limb model developed by the University of Denver. Two high demand activities were selected for the loading section of this study: step down (SD) and deep knee bend (DKB). Using the above model, 6 degree of freedom kinetics and kinematics for each activity was determined for each posterior stabilized implant design. Prior to loading, the 3-D motion between tibial implant and bone analog (micromotion) was measured using an ARAMIS Digital Image Correlation (DIC) system. Measurement was taken during the simulated DKB at 0.25Hz using an AMTI VIVO simulator while the DIC system captured images at a frame rate of 10Hz. The GOM software calculated the distance between reference point markers applied to the posterior implant and foam bone. A Matlab program calculated maximum micromotion within each DKB cycle and averaged that value across five cycles. The implant specific loading parameters were then applied to the three tibial implant designs. Using an AMTI VIVO simulator each sample was subjected to 50,000 DKB and 120,000 SD cycles at 0.8Hz in series; equating to approximately 2 years of physiological activity. Following loading, micromotion was measured using the same method as above.Introduction
Methods
The aim of this study was to document the survivorship and patient reported outcome of the Avon patello-femoral replacement in a consecutive series with follow up of 10 years or more. All cases performed in Bristol from 1996 onwards were prospectively recorded. Follow up was at 1,2,5,7,10,12 and 15 years with the Bristol Patella Score, the Oxford and WOMAC scores and SF12. Implant survival was analysed using the Kaplan-Meier method. There were 323 PFJ replacements (280 individuals). Follow up was available for 286 cases in 250 patients (89% follow up). The 10 year survival rate was 77%, falling to 67% at 15 years. The most common reason for revision was tibio-femoral progression (45/74 revisions), with loosening or polyethylene wear recorded in 8 cases. The best results were seen in the youngest and the oldest patients. Good improvements were seen in PROMs, with the mean OKS improving from 19.5 to 34.1 at 2 years and 32.7 at the 15 years. The Avon patello-femoral knee replacement is a successful long-term treatment for isolated patello-femoral knee osteoarthritis, although further improvements are expected in subsequent series, particularly as indications for surgery have evolved over time.
The aim of this study is to document the outcome of a large cohort of patients treated with the Bereiter trochleoplasty with between 1 and 12 years of follow up. 215 consecutive cases in 186 patients were recorded prospectively. All patients were offered yearly clinical and radiological review. PROMs were recorded including the IKDC, OKS, Kujala and SF-12. Patients unable to attend clinic were assessed with PROMS and radiographs from their local institutions where possible. There were 133 females and 53 males, with a mean age of 21 (14–38). There were no infections and only 6 patients reported further dislocations. There was one flap breakdown and no identified cases of secondary osteoarthritis. PROMs were available for 194 cases in 167 patients (90% follow up). 84% of patients were satisfied, 87% felt their symptoms had improved and 69% had gone back to sport. All scores improved (all p<0.001) except for the SF-12 mental score (p=0.42), with averages comparable to the results of MPFL reconstruction. Good outcomes were observed despite the difficult patient population in which these cases were performed. The Bereiter trochleoplasty is an effective method of treating recurrent patella instability in patients with severe trochlea dysplasia.
For many patients, total knee replacement (TKR) provides pain relief and restores motion for many years [1]. Some patients, however, experience early failures and require revision surgery. One of the suggested contributors to early failure has been excessive wear due to malalignment [2]. Previous work has shown that varus-valgus malalignment results in extreme condylar loading and could lead to high wear [3]. The purpose of this experiment, therefore, was to evaluate medial/lateral load sharing in an in vitro wear simulation. Wear testing was conducted on midsized Attune and Sigma fixed bearing cruciate substituting TKR components (DePuy Synthes). The two systems differ in many aspects; notably, Attune employs antioxidant-stabilized moderately-crosslinked polyethylene and a gradually changing sagittal femoral curvature while Sigma uses remelted moderately-crosslinked polyethylene and a mulit-radius femoral design. Wear was evaluated across a wide range of medial/lateral (M/L) load splits: 10/90, 60/40, and 90/10 using an AMTI six-station knee simulator (Figure 1). Simulation was conducted for 3 million cycles using at 1 Hz using previously described methods [4] with ‘High Kinematic’ displacement controlled inputs in 25% bovine calf serum (Hyclone) at 37 ± 2°C supplemented with sodium azide and EDTA. Polyethylene wear was determined gravimetrically with load soak compensation every 0.5 Mcyc.Introduction
Methods
Previous studies have demonstrated the need of accurate reduction of ankle syndesmosis. Measurement of syndesmosis is difficult on plain radiographs. Recently, a difference of 2mm in anterior and posterior measurements at incisura of the inferior tibio-fibular joint on CT has been described as a measure of malreduction (depicted as ‘G’ for ease of description). Our practice changed towards routine post operative bilateral CT following syndesmosis fixation to assess the reduction and identify potential problems at an early stage. The aim of this primarily radiological study was to determine if the use of bilateral cross sectional imaging brings additional benefit above the more conventional practice of unilateral imaging. Between 2007 and 2009, nineteen patients with ankle fractures involving the syndesmosis were included in the study group who had bilateral CT post operatively. The values of ‘G’ and the mean diastasis (MD) were calculated, representing the average measurement between the fibula and the anterior and posterior incisura.Introduction
Method
The use of a quadrupled hamstring graft in ACL reconstruction is well established. There are many described techniques in securing graft fixation, the optimal method is not yet established. The aim of this study was to review the results of a single surgeon series using the above implants looking at functional outcome for the patient and implant survivorship. Patients were recruited for the study who had completed 8 months of post-op rehabilitation following primary ACL reconstruction and that had received the same surgical technique using the same implants from one surgical team. Patients undergoing a revision procedure were excluded. All patients received the same post-operative rehabilitation. Those who met the inclusion criteria were contacted via a postal survey using the Lysholm and Tegner questionnaires. In total 77 patients were eligible for inclusion, consisting of 10 females and 67 males with a mean age of 31 (range 16-56). A 77% survey return rate was achieved with average follow up of 25 months (range 9-44). The mean Lysholm score was 82.1, with 59% ranking their knee as good or excellent. On average patients dropped 1.8 levels on the Tegner activity rating from a pre-injury average of 7.5 to post rehabilitation average of 5.7. There was a 100% survivorship of implants with no revisions undertaken due to implant failure. The study has shown that this cohort of patients has produced self reported outcomes analogous to findings in the current literature. No obvious problem with implants was observed. It has highlighted the multiple factors associated with the outcome of ACL reconstruction and demonstrates that the quadrupled HT graft using Bio-Intrafix and Rigidfix implants produces short to mid-term functional and activity levels in keeping with the literature standard.
To review the results of a single surgeon series using the above implants looking at functional outcome and implant survivorship. The outcome of ACL reconstruction is multi-factorial. There are many described ways of securing a 4-srandd hamstring ACL graft with no clear gold standard.AIMS
BACKGROUND
