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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_8 | Pages 80 - 80
11 Apr 2023
Oliveira J Simões J Noronha J Ramos A
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Validation of a new meniscal root repair technique that will be biomechanically superior to current gold standard procedures and, at the same time, will allow controlled adjustable fixation.

Medial and lateral meniscus from 10 porcine knees were collected. An iatrogenic posterior root tear was created and a single transosseous tibial tunnel technique that closely replicates the repair procedure with a 2-mm-wide-knottable braided tape was performed. Randomly, in one group (A) two simple cinch stitch were applied to suture the posterior root of the meniscus and, in the other group (B), a simple stich that holds the meniscus in two points in a crosse match configuration was used. For final fixation, alternating surgeon's knots (A group) and a doubled suture knot that allows an adjustable fixation were used (B group). All repairs were standardized for location and the repair stiches were placed in the body of the meniscus.

The new suture configuration (B group) showed a better biomechanical performance in terms of load for both the medial [151,0-560,3] 306,9±173,8N and the lateral posterior root fixation [268,2-463,1] 347,4±74,3N in comparison to the cinch stitch (A group) [219,0-365,2] 268,9±58,7N and [219,0-413,6] 318,0±72N. The maximum stiffness was also higher for the new tested suture configuration (B group) for both the medial meniscus [10,6-34,5] 18,9±9,2N/mm vs [7,1-12,7] 10,9±2,2N/mm and the lateral meniscus [16,0-27,9] 21,6±5,5N/mm vs [7,6-15,6] 12,6±3,5N/mm.

The presented new meniscal root repair is biomechanically superior to current gold standard techniques, as the cinch stich made with tape, keeping the simplicity and reproducibility of the procedure and, at the same time, is economically advantageous since a single tape in needed and allows adjustable fixation of the repair over a button.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_13 | Pages 75 - 75
1 Nov 2021
Ramos A Matos M
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Introduction and Objective

The patients with a total hip arthroplasty is growing in world manly in Europe and USA, and this solution present a high success at 10years in several orthopaedic registers. The application of total press-fit hip fixation presents the most used solution, but presents some failures associated to the acetabular component fixation, associated to the load transfer and bone loss at long term. The aim of this work is to investigate the influence of different acetabular bone loss in the strain distribution in iliac bone. To evaluate implant fixation, an experimental study was performed using acetabular press-fit component simulating different acetabular bone loss and measuring the strain distribution.

Materials and Methods

The experimental samples developed was based in an iliac bone model of Sawbones supplier and a acetabular component Titanium (Stryker) in a condition press-fit fixation and was implanted according surgical procedure with 45º inclination angle and 20º in the anteversion angle. Were developed five models with same initial bone, one with intact condition simulating the cartilage between bones and four with different bone loss around the acetabular component. These four models representing the evolution of bone support of acetabular components presented in the literature. The evolution of bone loss was imposed with a CAD CAM process in same iliac bone model. The models were instrumented with 5 rosettes in critical region at the cortical bone to measure the strain evolution along the process.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_11 | Pages 61 - 61
1 Dec 2020
Ramos A Mesnard M Sampaio P
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Introduction

The ankle cartilage has an important function in walking movements, mainly in sports; for active young people, between 20 and 30 years old, the incidence of osteochondral lesions is more frequent. They are also more frequent in men, affecting around 21,000 patients per year in USA with 6.5% of ankle injuries generating osteochondral lesions. The lesion is a result of ankle sprain and is most frequently found in the medial location, in 53% of cases.

The main objective of this work was to develop an experimental and finite element models to study the effect of the ankle osteochondral lesion on the cartilage behavior.

Materials and Methods

The right ankle joint was reconstructed from an axial CT scan presenting an osteochondral lesion in the medial position with 8mm diameter in size. An experimental model was developed, to analyze the strains and influence of lesion size and location similar to the patient. The experimental model includes two cartilages constructed by Polyjet™ 3D printing from rubber material (young modulus similar to cartilage) and bone structures from a rigid polymer. The cartilage was instrumented with two rosettes in the medial and lateral regions, near the osteochondral region. The fluid considered was water at room temperature and the experimental test was run at 1mm/s. The Finite element model (FE) includes all the components considered in the experimental apparatus and was assigned the material properties of bone as isotropic and linear elastic materials; and the cartilage the same properties of rubber material. The fluid was simulated as hyper-elastic one with a Mooney-Rivlin behavior, with constants c1=0.07506 and c2=0.00834MPa. The load applied was 680N in three positions, 15º extension, neutral and 10º flexion.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_4 | Pages 22 - 22
1 Apr 2019
Ramos A Bola M Simoes JA
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Introduction

Shoulder arthoplasty has increased in the last years and its main goal is to relieve pain and restore function. Shoulder prosthesis enters in the market without any type of pre-clinical tests. Within this paper we present study experimental and computational tests as pre-clinical testing to evaluate total shoulder arthoplasty performance.

Materials and methods

An in vitro experimental simulator was designed to characterize experimentally the intact and implanted shoulder glenoid articulation. Fourth generation Sawbones® composite left humerus and scapula were used and the cartilage was replicated with silicone for the intact articulation (figure 1). In the intact experimental articulation we considered the inferior glenohumeral ligament as an elastic band with equivalent mechanical properties. For the implanted shoulder, the Comprehensive® Total Shoulder System (Biomet®) with a modular Hybrid® glenoid base and Regenerex® central post was considered (figure 2). The prostheses were implanted by an experienced surgeon and clinical results from orthopedic registers were collected.

The system structures were placed to simulate 90º in abduction, including the following muscle forces: Deltoideus 300N, Infraspinatus 120N, Supraspinatus 90N and Subscapularis 225N. The finite element model was created with tetrahedral linear elements with linear elastic and isotropic material for the humerus in figure 3, (Young's modulus for cortical bone − 16.5 GPa; trabecular bone − 124 MPa). Anisotropic behavior was considered for the scapula model (E11 = 342.1 MPa, E22 = 212.8 MPa, E33 = 194.4 MPa). The shoulder prosthesis was of polyethylene with 1GPa and titanium with 110 GPa. The Poisson's ratio was 0.3 in all material, except for polyethylene where we assumed a value of 0.4. A long-term post-operative condition was simulated.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_5 | Pages 29 - 29
1 Apr 2019
Soares dos Santos M Bernardo R Ramos A Ferreira JAF Simões JA
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Introduction

An increasing trend in the incidence of primary and revision bone replacements has been observed throughout the last decades, mainly among patients under 65 years old.10-year revision rates are estimated in the 5–20% range, mainly due to peri-implant bone loss. Recent advances allow the design of implants with custom-made geometries, nanometer-scale textured surfaces and multi-material structures. Technology also includes (bio)chemical modifications of the implants' surfaces. However, these approaches present significant drawbacks, as their therapeutic actuations are unable to: (1) perform long-term release of bioactive substances, namely after surgery; (2) deliver personalized stimuli to target bone regions and according to bone-implant integration states.

The Innovative Concept

Here we propose the design of instrumented active implants with ability to deliver personalized biophysical stimuli, controlled by clinicians, to target regions in the bone-implant interface throughout the patients' lifetime. The idea is to design bone implants embedding actuators, osseointegration sensors, wireless communication and self-powering systems. This work proposes an advanced therapeutic actuator for personalized bone stimulation, and a self-powering system to electrically supply these advanced implants.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_2 | Pages 24 - 24
1 Jan 2017
Bola M Ramos A Simões J
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Total shoulder arthroplasty is a well-tested procedure that offers pain relief and restores the joint function. However, failure rate is still high, and glenoid loosening is pointed as the main reason in orthopedic registers. In order to understand the principles of failure, the principal strain distributions after implantation with Comprehensive® Total Shoulder System of Biomet® were experimental and numerically studied to predict bone behavior.

Fourth generation composite left humerus and scapula from Sawbones® were used. These were implanted with Comprehensive® Total Shoulder System (Biomet®) with a modular Hybrid® glenoid base and Regenerex® glenoid and placed in situ by an experienced surgeon. The structures were placed in order to simulate 90º abduction, including principal muscular actions. Muscle forces used were as follows: Deltoideus 300N, Infraspinatus 120N, Supraspinatus 90N, Subscapularis 225N.

All bone structures were modeled considering cortical and the trabecular bone of the scapula. The components of prosthesis were placed in the same positions than those in the in vitro models. Geometries were meshed with tetrahedral linear elements, with material properties as follows: Elastic modulus of cortical bone equal to 16 GPa, elastic modulus of trabecular bone equal to 0.155 GPa, polyethylene equal to 1GPa and titanium equal to 110 GPa. The assumed Poisson's ratio was 0.3 in all except for polyethylene where we assumed a value of 0.4. The prosthesis was considered as glued to the adjacent bone. The finite element model was composed of 336 024 elements.

At the glenoid cavity, the major influence of the strain distributions was observed at the posterior-superior region, in both cortical and trabecular bone structures. The system presents critical region around holes of fixation in glenoid component. At the trabecular bone, the maximum principal strains at the posterior-superior region ranged from 2250 µε to 3000 µε. While at the cortical bone, the maximum principal strains were 300 µε to 400 µε.

The results observed evidence some critical regions of concern and the effect of implant in the bone strains mainly at the posterior-superior region of the glenoid cavity is pronounced. This indicates that this region is more affected by the implant if bone remodeling is a concern and it is due to the strain-shielding effect, which has been connected with loosening of the glenoid component.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_2 | Pages 51 - 51
1 Jan 2017
Ramos A Mesnard M
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The Temporomandibular joint (TMJ) is a complex and important joint for daily activities, and the alloplastic implant is recommended as the best solution, after repeated surgeries, failed autogenous grafts, highly inflammatory metabolic arthritis, fibrous or bony ankyloses. Some complications in total TMJ replacement are associated with implant design, screw fixation failure, implant displacement, fibrous tissue formation, (Speculand, et al. 2000). Some numeric studies evaluate the number of screws needed to guarantee the good fixation and suggest a minimum of three (Ramos et al. 2015), but is a controversy conclusion. The Biomet Microfixation TMJ stock prosthesis, Jacksonville, FL, USA is one of the three or four in the market. Clinical studies published by this device between 2005 and 2015 indicate a success rate of around 84 to 91% with improvements in mouth opening, a decrease in pain score and improved quality of life. The present study analyses experimentally the load transfer of this device.

The intact, clean cadaveric ramus was instrumented with four rosettes model (KFG-1-120-D17-11 L3M2S, by Kywoa Electronic Instruments Co™, Japan), one in lateral region, two in lateral region and one in lingual face. The condyle was loaded with the temporal reaction; the load was applied constant velocity of 1mm/min in three continuum phases and with three stops at 100N, 200N and 300N. Next, the Biomet microfixation implant was fixed to the same cadaveric mandibular ramus after resection. The implant was 50mm in length. It was fixed with five 6AL/4V Titanium self-tapping screws with 2.7mm diameter were long enough to establish a bi-cortical support. The screws were screwed into the bone with a torque-screwdriver a constant torque of 0.2Nm. The same rosettes were analyzed before and after implantation and the mandible displacement two.

The experimental results for the mandibular ramus present a linear behavior up to 300N load in condyle, with the Biomet implant influencing strain distribution; the maximum influence was near the implant (rosette #4) is around 59%. The average vertical displacement of the mandibular ramus (300N) was measured by machine: 1.18 (±0.02) mm for the intact mandibular ramus and 1.21 (±0.02) mm for the implanted one, which represents a 2.8% differences between the experimental models and reduce of stiffness. The maximum principal strain deformation was observed in the rosette #3 with 1360µε more 20% than the intact mandible for 300N of reaction.

The experimental results show that the Biomet TMJ mandibular ramus implant changes the load transfer in the ramus, compared to the intact, with its strain shielding effect. The results indicate the minimum number of screws is three to guarantee a good load transfer but the surface preparation of condyle presents an important factor.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_2 | Pages 64 - 64
1 Jan 2017
Pereira J Ramos A Completo A
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Positioning of the hip resurfacing is crucial for its long term survival and is critical in young patients for some reasons; manly increase the wear in the components and change the load distribution. THR have increased in the last years, mainly in young patients between 45 to 59 years old. The resurfacing solution is indicated for young patients with good bone quality. A long term solution is required for these patients to prevent hip revision. The resurfacing prosthesis Birmingham Hip Resurfacing (BHR) was analyzed in the present study by in vitro experimental studies. This gives indications for surgeons when placing the acetabular cup.

One synthetic left model of composite femur (Sawbones®, model 3403), which replicates the cadaveric femur, and four composite pelvic bones (Sawbones®, model 3405), were used to fix the commercial models of Hip resurfacing (Birmingham model). The resurfacing size was chosen according to the head size of femurs with 48 mm head diameter and a cup with 58 mm. They were introduced by an experimented surgeon with instrumental of prosthesis. The cup is a press fit system and the hip component was cemented using bone cement Simplex, Stryker Corp. The acetabular cup was analyzed in 4 orientations; in anteverion with 15º and 20°; and in inclination 40 and 45°. Combinations of these were also considered

The experimental set-up was applied according to a system previously established by Ramos et al. (2013) in the anatomic position. The femur rotates distally and the Pelvic moves vertically as model changes, such that the same boundary conditions are satisfied. This system allows compensating motions of the acetabular cup orientation. A vertical load of 1700 N was applied on all cases, which have resulted in joint reaction force of 2.4 kN. The femur and iliac bone was instrumented with rosettes. 5 repetitions at each position were conducted.

When the femur was instrumented with three rosettes in medial, anterior and posterior aspect, the maximum strain magnitude was observed in the medial aspect of femur with a minimum principal strain of −2070µε for 45° inclination and 20° of anterversion. The pubic region was found most critical region after instrumenting the Iliac bone with four rosettes, with a minimum principal strain around −2500µε (rosette 1), for the 45° inclination and 20° of anterversion. We have observed the great influence of the inclination on the strain distribution, changing its magnitude from compression to traction in different bone regions.

The minimum principal strain is more critical in medial aspect of the femur and the influence of strain is about 7% when orientation and inclination change. The maximum influence was observed in the anterior aspect, where the anteversion presents a significant influence. The results show the interaction between inclination and anterversion in all aspects, being observed lower values in lower angles.

The orientation of the acetabular cup significantly influences the strain distribution on the iliac surface. Besides, as anterversion increases, more strains are induced, mainly in the region of iliac body (rosette 3).


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 126 - 126
1 Jan 2016
Ramos A Duarte RJ
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Introduction

The number of total hip replacements (THR) increased around 3.5% by year in last decade. Osteoarthritis is the most important disease in the hip, with a prevalence of 10% in the older population (>85 years), according to the Swedish THA Register. THR have been increasing in last years, mainly in young patients between 45 to 59 years old. This type of patients needs a long term solution to prevent hip revision. Two commercial solutions for young patients, the resurfacing prosthesis and press fit one, were analysed in the present study by experimental and numerical models.

Methods

Two synthetic left models of composite femur (Sawbones®, model 3403), which replicates the cadaveric femur, and two composite pelvic bones were used to introduce two Comercial models of Hip resurfacing (Birmingham model) and Press-fit stem (Laffit Selft –locking stem press-fit model). The commercial hip stems were chosen according to the femurs head size (resurfacing) and the femur size to press-fit Hip stem. Then, they were introduced by an experimented surgeon. The experimental set-up was applied according to a system defined previously by Ramos et al. (2013). Numerical models were implemented by replicating the experimental tests. A 3D scanning was used to identify the stem position in each model. The properties of cortical and cancel bone and hip prosthesis were also taken into account by these models. Contact was established in the interfaces for both press-fit solutions. The femur rotates distally and Pelvic moves up and down according model changes, in order to guarantee models with the same boundary conditions.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 127 - 127
1 Jan 2016
Ramos A Duarte RJ
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Introduction

Hip resurfacing arthoplasty (HRA) is an alternative to total hip arthroplasty (THA), which has increased in the last years, especially in young patients. A suitable positioning of the resurfacing head is important, mainly because it is strongly related with the neck fracture. The goal of this work was to evaluate the influence of the resurfacing head positioning in the load distribution along the femurs’ structures.

Materials and methods

Using 3D scan technology, the exterior geometry of a composite femur, used to create the FE models, was obtained. Three resurfacing models were used in three different positions in the frontal plane. A model with a positive offset of +5mm (Resurfacing #1), in neutral position (Resurfacing #2), and with a negative offset of −5mm (Resurfacing #3) was developed. A Birmingham® Hip Resurfacing prosthesis was chosen according to the femurs’ head. It was positioned in the femur and acetabulum by an experimented surgeon. The metal on metal contact pair was implemented. Models were aligned with 7° and 9°, considering the position of the anatomical femurs in sagittal and frontal planes. Models were constrained on the wing of the ilium and ischial tuberosity, allowing only vertical and rotational movements on the iliac side. Femurs were constrained on its distal side, allowing only rotational movements.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XL | Pages 151 - 151
1 Sep 2012
Ramos A Relvas C Completo A Simoes JA
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Introduction

The orthopaedic market offers more than two hundred different hip femoral stems. Of these, very few have undergone scientific studies with published results. The differences of designs of the stem are mainly related to surface texture and geometry sections. The development of a new cemented hip prosthesis is certainly a very hard task if aiming the improvement of actual performance.

Materials and Methods

This study presents the influence of geometric variables in a novel hip stem concept which was based on the comparison of the performance of the best cemented stems actually in the market. The study was developed using finite element analysis and experiments with in vitro femoral replacements. A numerical simplified model of the hip replacement was designed to generate the final geometry of the femoral stem section. After an in vitro cemented commercial stem was done, with the best cemented stem a Lubinus, Charnley, Stanmore and Müller. Realistic numerical models also allowed us to determine cement mantle stresses of commercial femoral stems that were compared with those obtained for the new concept stem. The new model was then prototyped and tested through in vitro fatigue tests. Finally fatigue tests were also performed to determine the density of cracks in the cement mantles, as well as debonding for both conventional and new designs.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 272 - 272
1 Jul 2008
RAMOS-VÉRTIZ A
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Purpose of the study: The outcomes of different stabilization methods for unstable forearm fractures are described.

Material and methods: From January 1980 through December 2000, 29 patients were treated at the central military hospital orthopedics uint for proximal forearm fractures, 27 underwent surgery. We used the Beaufils classification, depending on the localization of the ulnar fracture. Type 1: metaphyseal fracture (n=12) with dislocation of the radial cup; type 2: epiphyseal fracture with transolecraneal dislocation (n=6); type 3: metaphyso-epiphyseal fracture with anterior dislocation (n=5); type 4: metaphyso-epiphyseal fracture with posterior dislocation (n=5).

Results: Outcome was assessed at six months to 20 years follow-up. According to the Morrey classification, outcome was excellent for six patients, good for nine, fair for seven and poor for three. Six patients had a stiff joint, one had a synostosis and three nonunion.

Conclusion: To achieve satisfactory outcome, it is crucial to achieve internal fixation of the proximal ulna and reconstruction of the radial length. Resection without replacement of the radial cup is contraindicated in these associated fractures.