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Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 324 - 324
1 Jul 2008
Steele RG Newman JH Hutabarat S Evans R Ackroyd CE
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Purpose of Study: Fixed bearing unicompartmental knee replacement (UKR) has become popular since several series have shown good 10 year survivorship and excellent function. However little is known about survival during the second decade.

Method: From the Bristol database of over 4000 knee replacements 203 St. George Sled UKR’s which had already survived 10 years were identified. The mean age at surgery was 67 years (48–85), with 64% being female. This cohort has been further reviewed at an average of 14.8 years (10–30) from surgery to determine survivor-ship and function.

Results: Survivorship during the second decade was 87.5%. 58 patients (69 knees) had deceased with implant in situ, only 2 after revision. A further 15 UKR’s have been revised at an average of 13 years post op; 7 for progression of disease, 4 for tibial loosening, 3 for polyethylene wear, 2 for femoral component fracture and 2 for infection.

99 knees were followed for 15 years and 21 knees for 20 years. The average Bristol knee score of the surviving knees fell from 86 to 79 during the second decade.

A previous study showed an 89% 10 year survivor-ship and this is now extended to 82% at 15 years and 76.5% at 20 years.

Conclusion: Satisfactory survival of fixed bearing UKR can be achieved in the second decade suggesting that the indications for mobile bearings require careful definition since there is a higher incidence of complications in many people’s hands.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 325 - 325
1 Jul 2008
Kulkarni MM Eldridge JD Newman JH
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Introduction: Anterior Knee pain is a very common presentation in Orthopaedic out patient clinics. However, Trochlear Dysplasia as a condition is still not very well understood.

Materials and Methods: Operative findings in patients undergoing Trochleaplasty and in young patients undergoing Patella-femoral arthroplasty were studied. Patients having trochlear dysplasia were identified. All these patients were sent a questionnaire to explore the variety of symptoms they experienced. 87 patients were identified for the study. 71(82%) patients responded to the questionnaire.

Results: Two subgroups were identified, one with dislocation of patella and the other without dislocation of the patella. Patients in patella dislocation group were younger (12 years vs 24) than those who presented without dislocation of patella. Patella dislocation group had more patients with anterior knee pain (71% vs 52%) as teenagers as compared to the group without dislocations. Symptoms such as giving way, lack of trust and unable to participate in sports were more commonly seen in the group with patella dislocation whereas, limited walking distance and difficulty with climbing the stairs were more commonly seen in the group without dislocation. Symptoms such as pain, catching and locking were seen equally amongst the two groups.

Conclusion: We believe that the patients with trochlear dysplasia have a bimodal presentation. Patients with dislocation of patella present earlier than those without patella dislocation. These two groups also have different symptoms at presentation. It is important to identify these subgroups correctly for appropriate management.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 329 - 329
1 Jul 2008
Davis CR Newman JH Davies AP
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The purpose of this study was to determine the incidence of revision total knee replacement (TKR) within 5 years of the index procedure at a large multi-surgeon unit using a single prosthesis and to determine the cause of failure of those implants.

This was a retrospective review of all primary Kine-max Plus TKR performed at the Avon Orthopaedic Center between 1.1.1990 and 1.1.2000. Cases were identified that required revision arthroplasty in any form within 5 years of the index procedure. Case notes and Xrays were reviewed to determine causes of failure.

There were 2826 primary Kinemax Plus TKR performed during the study period. Of these 20 were known to have required revision surgery within 5 years. 8 were revised for deep infection of the prosthesis and 12 for aseptic causes. The overall incidence of premature failure of the Kinemax Plus TKR at 5 years was 0.71%. The incidence of aseptic premature failure at 5 years was 0.42%. Detailed examination of the clinical records indicated that some form of technical error at the time of the index arthroplasty was responsible for the early failure of 6 prostheses. This equates to 0.21% of the procedures performed. Aseptic loosening of the remaining 6 cases could not be attributed to a specific cause.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 325 - 325
1 Jul 2008
Clare TD Newman JH
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Introduction: Following previously gratifying results in older patients the study aims to quantify the outcomes and identify any contraindications in patient selection for patello-femoral replacements using the Avon pros-thesis in patients under 55 years old.

Method: We present early outcome results for a prospective cohort study of patients under 55 years of age.110 knees in 86 patients (median age 47years, range 25–54) have been treated with Avon patello-femoral replacement (88 in females and 22 in males). Diagnoses included lateral facet OA (59 knees), patella dislocation (36 knees), trochlear dysplasia (39 knees) and post patellectomy instability (7 knees). 108 knees had undergone previous surgery. 14 knees required additional intra-operative procedures (including 11 lateral releases and 2 patella realignments). All patients were assessed pre-operatively using the Oxford, Bristol and WOMAC scores.

Results: No knees have been lost to follow-up. 82 knees have post operative scores available (mean follow-up 27 months). 8 have been revised (6 due to progression of OA). The mean Oxford, Bristol and WOMAC scores all improved: 18 to 32, 56 to 83 and 39 to 25 respectively. Asymptomatic deterioration of the tibio femoral joint is seen in some cases of primary OA but not with trochlear dysplasia. 21 knees required post-operative additional procedures including 6 lateral releases, 3 patella realignments and 5 revisions. Equally good results were seen when comparing patients with the 3 main diagnoses. Trochlear dysplasia is strongly predicted by young age at onset of symptoms and patellar dislocation.

Conclusion: Many of this type of patient, with disabling symptoms, wish to “live now”. The short-term improvements are frequently dramatic. Comparison of underlying pathologies has not identified groups that are performing less well to suggest restricting current indications. As yet there is no suggestion of prosthetic failure. Revision has presented little difficulty since minimal bone is resected primarily.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 17 - 18
1 Mar 2008
Patel R Stygall J Harrington J Harrison M Newman S Haddad F
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To quantify the intraoperative cerebral microemboli load during primary total knee arthroplasty (TKA) using transcranial Doppler ultrasound and to investigate whether a patent foramen ovale influences cerebral embolic load in general.

Patients undergoing primary TKA, with no history of stroke, TIA, ongoing CNS disease or alcoholism were included. All operations were carried out under a standardised general anaesthetic and performed by two consultant orthopaedic surgeons. Microemboli l oad was recorded, using transcranial Doppler ultrasound (TCD), onto VHS tape for subsequent playback and analysis. Patent foramen ovale detection was performed using bolus intravenous injection of agitated saline followed by valsalva manoeuvre technique and TCD. Timing of specific surgical steps was recorded for each operation and emboli load calculated for that period.

Results: 50 TKA patients were studied (31 females, 19 males); 28 right and 22 left TKAs were performed. Cerebral microembolisation occurred in 19 patients (42%). Mean microembolic load was 3.56 per patient (range 0–21). PFO was detected in 9 patients (18%). Two thirds of PFO positive patients displayed cerebral microemboli. However, 36.6% (n=15) of PFO negative patients also displayed microemboli intraoperatively. Deflation of the tourniquet was followed by a larger microembolic load than the other phases of the operation.

Conclusion: Intraoperative cerebral microembolisation occurs in a significant proportion of patients during total knee arthroplasty. The presence of a patent foramen ovale does not appear to influence the incidence microemboli intraoperatively. Specific surgical activities are associated with generating greater embolic loads. These questions will be comprehensively assessed in the larger study currently underway.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 167 - 167
1 Mar 2008
Hollinghurst D Stoney J Ward T Gill H Beard D Newman J Murray D
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Medial unicompartmental replacement (UKR) has been shown to have superior functional results to total knee replacement (TKR) in appropriately selected patients, and this has been associated with a resurgence of interest in the procedure. This may relate to evidence showing that the kinematic profile of UKR is similar to the normal knee, in comparison to TKR, which has abnormal kinematics. Concerns remain over the survivorship of UKR and work has suggested the anterior cruciate ligament (ACL) may become dysfunctional over time. Cruciate mechanism dysfunction would produce poor kinematics and instability providing a potential mechanism of failure for the UKR.

Aim: To test the hypothesis that the sagittal plane kinematics (and cruciate mechanism) of a fixed bearing medial UKR deteriorate over time (short to long term).

A cross sectional study was designed in which 24 patients who had undergone successful UKR were recruited and divided into early (2–5 years) and late (> 9 years) groups according to time since surgery. Patients performed flexion/extension against gravity, and a step up. Video fluoroscopy of these activities was used to obtain the Patellar Tendon Angle (PTA), the angle between the long axis of the tibia and the patella tendon, as a function of knee flexion. This is a previously validated method of assessing sagittal plane kinematics of a knee joint.

This work suggests the sagittal plane kinematics of a fixed bearing UKR is maintained in the long term. There is no evidence that the cruciate mechanism has failed at ten years. However, increased tibial bearing conformity from ‘dishing’, and adequate muscle control, cannot be ruled out as possible mechanisms for the satisfactory kinematics observed in the long term for this UKA.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 143 - 144
1 Mar 2008
Friedman R Longo J Cherry K Newman M Jessup D Bal S
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Purpose: Ceramic/ceramic bearing surfaces have the advantage of significantly decreased wear and high biocompatibility compared to CoCr/PE or ceramic/PE. The purpose of this randomized, controlled, multi-center, prospective study was to evaluate the clinical and roentgenographic results of 469 ceramic/ceramic versus 321 ceramic/PE THA at a 2 to 7 year follow-up.

Methods: The ceramic/ceramic THA had a polished alumina femoral head articulating with a polished alumina acetabular liner seated into the metal acetabular shell designed to avoid any impingement of the ceramic liner on the femoral component. Evaluations were completed preoperatively, at 6 months and yearly postoperatively.

Results: Mean age of the 790 patients was 59 years, with slightly more females. There were no significant demographic differences between the two groups. The main diagnoses were OA in 74% and osteonecrosis in 19%. Preoperatively the mean Harris Hip Score (HHS) and WOMAC scores were 44 and 41, respectively, and did not differ significantly between the two groups. At follow-up, the mean HHS was 93 for the ceramic/ ceramic THA and 93 for the ceramic/PE THA. The mean WOMAC scores showed no differences at follow-up. Roentgenographic analysis revealed one acetabular cup migration with a PE liner. One ceramic liner fractured upon insertion that was not properly positioned prior to impaction. Otherwise, there were no revisions or complications related to either bearing surface.

Conclusions: This short-term study has demonstrated efficacy and safety of a ceramic/ceramic bearing surface compared to the standard ceramic/PE surface currently used in clinical practice, with no failures or complications related to the bearing surface. Further follow-up is indicated to determine the long-term outcome.

Funding : Commerical funding

Funding Parties : Encore Orthopaedics


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 18 - 19
1 Mar 2008
Prem H Aravindan S Mowbray M Newman-Sanders A
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70 patients who underwent dynamic MRI scanning for chronic anterior knee pain were retrospectively evaluated. All patients had been symptomatic for over a year. 43 patients had been treated conservatively and 27 had undergone surgical procedures (arthroscopy -13, lateral release- 9, tibial tubercle transfer 5). The extent of subluxation, tilt and cartilage abnormalities on MRI scans, during resisted extension were assessed. Functional scoring (Oxford, Lysholm and Tegner scores) was done through questionnaires and correlated with the radiological findings.

54 (77%) patients were found to have some patellofemoral abnormality on the scans. Subluxation was the most common finding with mild subluxation in 30, moderate in 18 and severe in 17 knees. Mild tilt was seen in 26 knees and moderate to severe tilt in 14 knees. Tilt was found in association with subluxation except in 8 cases. Grade 1 and 2 cartilage wear were seen in 13 knees and Grade 3 and 4 in 21 knees.

The “Tibial Tubercle to Trochlear Groove distance” (TTD) was measured in all knees and correlated with subluxation. The average distance was 13.5mm, 13.6mm and 18.8mm for mild, moderate and severe subluxation respectively. All patients with a TTD _ 20mm had moderate or severe subluxation. The specificity of a TTD _ 20mm for severe maltracking was 100% but the sensitivity was only 42%.

The TTD appears to be the single most significant parameter determining patella tracking. We have proposed an algorithm for the surgical and non-surgical treatment of chronic anterior knee pain. We recommend lateral release for those with moderate and severe subluxation and a tibial tubercle transfer as well in those with a TTD _ 20mm. The functional scores did not zshow a significant correlation with the grading of subluxation.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 259 - 259
1 May 2006
Davies H Khan OH Weale AE Newman JH
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Purpose of study: To examine the fate of the non operated on compartment of the knee, following unicompartmental knee replacement (UKR), by radiological assessment 10 years after operation.

Summary of methods and results: A total of 50 UKRs were performed on 45 carefully selected patients between 1989 and 1992. Fifteen patients died, two patients were lost to follow-up and two knees were revised. The radiographs of the remaining 30 knees were reviewed three times by blind and randomised assessment using Ahlback and Altman scoring systems to measure the progression of osteoarthritis within the joints. Standard long-leg weight-bearing anteroposterior views of the knee and skyline views of the patello-femoral joint were taken before, at eight months and ten years after operation. Two knees showed evidence of progression of osteoarthritis within the patello-femoral joint and three knees showed some progression of the opposite tibio-femoral compartment.

Statement of conclusion: Our study provides evidence that after ten years progressive OA within the retained compartments following UKR is rare and usually minor.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 256 - 256
1 May 2006
Hassaballa MA Mehendale S Porteous AJ Newman JH
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Aim: To assess the results of aseptic and aseptic cases using the PFC/TC3 system, and to correlate this with the restoration of joint line height.

Method: 148 patients underwent revision TKR using the PFC/TC3 system. No re-revision cases were included in this series. Data was prospectively collected (using the Bristol Knee Score) pre-operatively and at a mean of 4.2 years post-revision. 31 revisions were for infection and 53 revisions were for aseptic loosening. Revision for infection was done as a two-stage procedure and aseptic as a single operation. Measurements of the joint line height were made pre and post-operatively using Figgie’s method. The cases were divided into 3 groups on the basis of joint line restoration:

Lowered by more than 5 mm

Restored

Elevated more than 5 mm

Results: The mean pre-op total score for the infection group was 35/100 and 40/100 for the aseptic loosening group. The total score post-operatively was 67 for the infection group and 73 for the aseptic loosening group. The joint line was restored in 50% of infected cases and in 60% of aseptic loosening cases.

Conclusion: although the overall results were slightly less satisfactory for the infected revision group, there was no significant difference between the two groups either in total BKS scores or in reproduction of the joint line. The average outcome was much less good than for primary TKR.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 256 - 257
1 May 2006
Hassaballa M Weal A Porteous A Newman J
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Purpose: This study was carried out to compare the alteration in skin sensation following midline, medial and short medial incisions for knee replacement.

Method: 88 patients with 102 replaced knees were examined for altered skin sensation over the front of the knee, all were at least 18 months from their knee replacement. Twenty-one knees had a medial incision, 38 a midline incision and 43 a short medial incision for UKR.

A scale of −2 to +2 was used to measure different degrees of skin hypo or hyperaesthia. A purpose-designed grid, designed to fit different knee sizes, was used to record sensations. A computer programme was created to record all patients’ data including the length and shape of the incision in relation to anatomical landmarks.

A parallel histological study was carried out on 18 skin specimens taken from the 2 standard incisions. The specimens were prepared and stained for nerve endings. The number of nerve endings in each incision was calculated.

Results Histologically, less cutaneous nerve endings were seen in specimens from midline incisions than medial incisions.

Discussion: Altered skin sensation is unpleasant to many patients at least initially and may affect function especially kneeling. The midline line incision seems to produce less dermal parasthesia than the medial incision, this probably relates to both the wound position and the density of nerve endings. As expected, the length of incision correlated with the area of numbness when comparing short and long medial incisions.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 257 - 257
1 May 2006
Hassaballa MA Revill A Penny B Newman JH Learmonth ID
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Introduction: Correct prosthesis alignment and joint line reproduction in total knee replacement (TKR) is vital for a successful clinical outcome. It is acknowledged that the ideal coronal alignment of the knee following TKR should be between 4–10 degrees of valgus. A neutral or varus knee is associated with a higher failure rate. Previous studies have shown that ideal alignment is achieved in only around two-thirds of cases.

Joint line elevation > 8mm has been associated with inferior clinical outcome, and depression associated with retropatellar pain and increased risk of patella subluxation.

Recently, modifications have been made to the Kine-max-Plus Total Knee System instrumentation, theoretically providing better internal fixation to prevent a varus cut and a 12 mm measured resection from the “normal” tibial plateau. This study aims to examine whether these changes result in an improvement in alignment, and a more reliable restoration of joint line.

Materials and Methods: Two consecutive series, each of 75 patients who had undergone TKR using either the old (Group A) or the new (Group B) instrumentation were included in the study. Antero-posterior and lateral preoperative and postoperative knee radiographs were assessed using the American knee society radiographic analysis for prosthesis postionoing by 2 independent observers. The Tibial and Femoral Component Angles in the coronal plane (cTCA and cFCA) and in the sagittal plane (sTCA and sFCA) were measured, as was the change in joint line height.

Conclusion: Our results suggest that use of the new instrumentation is associated with better restoration of joint line, and is more effective in preventing implantation of the tibial component in varus. These figures relating to a modern instrumentation system provide a yardstick against which computer assisted and robotic surgery can be judged. Long-term follow-up will be required to assess the clinical significance of these results.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 251 - 251
1 May 2006
Newman J Hendrix M
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Introduction: This study assesses the prevalence of trochlear dysplasia as a cause of patello-femoral arthritis (PFOA), though for many years the condition was scarcely recognised and not recorded.

Method: Since 1989 385 primary isolated patello-femoral replacements have been performed in Bristol for patello-femoral arthritis.

The diagnoses recorded were:

Lateral facet PFOA 227

Symmetrical PFOA 95

Medial facet PFOA 24

Dislocation 15

Subluxation 33

Post traumatic 6

Trochlear dysplasia was noted either retrospectively or as “other diagnosis” in only 10 cases between 1989 and 2003, however in the last year, the condition became recognised locally, and has been recorded in 11 of the 48 cases performed.

A recent review of 40 cases aged under 55 showed evidence of causative trochlear dysplasia in more than 50%.

This was based on:

Trochlear dysplasia recorded on operative note 8

A positive crossing sign on a true lateral xray 19

A sulcus angle > 144° 20

Conclusion: Trochlear dysplasia frequently leads to severe symptomatic patello-femoral arthritis, often at an early age, and can be helped by isolated patello-femoral replacement. Since only 38 of the 385 cases had undergone re-alignment procedures it seems likely that the condition initially presents in a variety of ways.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 251 - 251
1 May 2006
Nicol S Howard M Newman J
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Introduction: Progressive symptomatic tibiofemoral arthritis following PFJR is an important cause of failure. This study is designed to quantify radiologically the degree of tibiofemoral disease progression in patients who have undergone PFJR in our institution.

Patients and Methods: A prospective series of 102 consecutive Avon PFJRs in 78 patients with a minimum follow-up of five years was analysed.

Available AP weight bearing radiographs of the knee taken at 8 months and 5 years postoperatively were examined in a random order twice by each of two surgeons who were blinded to the patient details and length of follow up. The severity of arthritis was graded using the classifications of Ahlback and Altman, giving a measure of arthritis progression.

Results and Discussion: Arthritis was seen to progress in 8.5–17% of medial and 11–17% of lateral compartments after PFJR. Statistically significant progression was demonstrated using the Altman but not the less sensitive Ahlback scoring system, suggesting that the former should be used in scoring the tibiofemoral joint prior to PFJR. Of those patients who had a preoperative tibiofemoral Altman score of zero, 87% showed no radiological evidence of disease progression at minimum 5 year follow up, suggesting that these are the ideal candidates for PFJR.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 108 - 108
1 Mar 2006
Hassaballa M Aueng J Hardy J Newman J Learmonth I
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Aim: The Low Contact Stress (LCS) Total Knee Replacements (TKR) is a well-established mobile bearing prosthesis with more than 25 year experience, while the Kinemax Plus is a well established fixed bearing prosthesis. We examined whether reproducing the joint line height to within 5 mm of the pre-operative joint line height had any impact on the clinical outcome in the two different types of Total Knee Replacements.

Method: 48 consecutive LCS knee replacements with a minimum of 2 years follow up had their pre and postoperative joint line (using Figgie’s method) and range of movement (ROM) measured. We used the Oxford Knee Score as a clinical outcome measurement tool.

A cohort group of 53 CR Kinemax plus TKR from the Bristol Knee group was matched for age and sex. They had the same parameters measured.

Results: Accurate joint line restoration was achieved significantly more frequently (P< 0.05) in the Kinemax group. Better post-operative ROM also occurred in the Kinemax group than the LCS, p = 0.03 and the former produced a bigger gain in ROM p < 0.01. However, no difference in the Oxford Knee Score existed between the two prostheses, p = 0.28.

Joint line: elevation K+ LCS

0–2 mm (16/48) = 33% (26/53) = 49% 2–5 mm (14/48) = 29% (14/53) = 26%> 5 mm (18/48) = 38% (12/53) = 25%

There was no significant difference in the ROM or Oxford Knee Score when the joint line was not elevated versus elevated for each prosthesis. However, there was suggestion that the ROM in LCS might be more sensitive to joint line changes, although this was not significant.

ROM

K+ LCS

Normal joint line 116° 105°

Elevated joint line 108° 101°

Conclusion: Accurate joint line restoration could not be shown to correlate with either improved ROM or Oxford knee score; probably because of the small mount of elevation encountered and the small study size. There was a significantly greater post-operative increase in ROM with the Kinemax Plus relative to the LCS, and a significantly closer restoration of the joint line with the Kinemax Plus, both with respect to the actual measurement and with respect to the proportion of cases in which the joint line was accurately reproduced. This is surprising since in most K+ cases additional distal femur had been resected to avoid a tight knee. While in the LCS group special efforts had been made to achieve accurate restoration of the joint level.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 173 - 174
1 Mar 2006
Ridgeway S Bhatnagar P Kharendesh P Gibbs J Newman K Khaleel A Elliott D
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Aim: To describe a radiographic biomechanical classification of tibial plateau fractures which dictates treatment. To compare the intra- and interobserver reliability and reproducibility of this, the Chertsey (C1-3) classification, and the Schatzker (SK1-6) classification.

Method: This classification system has been used at this institution for 8 years by the orthopaedic trauma consultants and consists of C1 – valgus fractures, C2 – Varus fractures and C3 axial fractures. Our treatment regime is based on this classification and results presented in a sperate study. These consultants were excluded from the study on reliability and reproducibility. 2 Orthopaedic consultants, 2 orthopaedic registrars and 2 radiologists were selected randomly to classify 30 sets of AP and Lateral radiographs, of randomly selected patients treated in this institution with tibial plateau fractures, consisting of 9 SK1-3/C1, 8 SK4/C2 and 13 SK5,6/C3 fractures, and again with the same radiographs in a random order 1 month later. Radiographs of fractures treated conservatively were excluded. Statistical analysis included Kappa concordance according to Landis and Koch, and the Mann-Whitney U test.

Results: The Schatzker system was only moderately reliable (K=0.66), and the Chertsey classification system significantly more reliable (K=0.82) (p=0.03) with regards to interobserver reliability. Excellent reproducibility (intra-observer reliability) was seen amongst all observers. The consultant orthopaedic surgeons were significantly more reliable than the radiologists, but not the orthopaedic registrars. No particular fracture type in any classification proved to be significantly more difficult to classify.

Conclusion: We present a classification used in our institution based on plain radiographs, which depicts investigations and treatment. The Chertsey classification is significantly more reliable between observers than the Schatzker classification and is reproducible.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 100 - 100
1 Mar 2006
Newman J Ackroyd C Evans R Gleeson R Webb J
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Introduction Unicompartmental Knee Replacement (UKR) has now become an accepted and widely used treatment for unicompartmental arthritis. Our unit has performed over 1000 UKRs in the past 22 years. The optimal mechanical design of the implant has yet to be determined.

Methods After gaining ethical approval a prospective randomised trial was commenced in 1999 to compare the 2–5 year results of a fixed bearing with a mobile bearing prosthesis. 104 knees in 91 patients underwent a UKR, the mean age of the group was 65 years and a mean weight of 80kg. 57 had a St Georg Sled fixed bearing prosthesis and 47 an unconstrained mobile bearing Oxford UKR. All were prospectively reviewed using the Oxford and Bristol Knee Scores.

Results All 104 knees have been reviewed at 2 years, with none lost to follow-up. 3 patients in the Oxford group suffered a dislocated meniscus and a further 4 required revision, as well as 3 in the St Georg Sled group. The overall function of the 2 groups was the same, but the Oxford mobile bearing group had significantly more persistent pain (p=0.013).

Conclusion The results in both groups were less satisfactory than previous series from this unit probably due to the efforts being made to use minimal incision. However the early complication rate was higher with the mobile bearing devise. This must be balanced against the possible better long-term survival.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 106 - 107
1 Mar 2006
Patel R Stygall J Harrington J Newman S Haddad F
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Aims: To assay the intraoperative cerebral microemboli load during primary total knee arthroplasty(TKA) using transcranial Doppler ultrasound. A battery of ten neuropsychiatric tests were carried out pre and post operatively to examine the change in cognitive outcome. The relationship between emboli load and neuropsychiatric outcome was examined.

Methods: Patients undergoing primary TKA, with no history of stroke, TIA, ongoing CNS disease or alcoholism included. Pre (baseline) and post operative (6 weeks and 6 months) neuropsychiatric tests performed. Scores were recorded as “z change” scores compared with baseline. All operations were carried out under a standardised general anaesthetic and performed by two consultant orthopaedic surgeons. Microemboli load recorded, using transcranial Doppler ultrasound (TCD), onto VHS tape for subsequent playback and analysis.

Results: 50 TKA patients were studied. Cerebral microembolisation occurred in 63% of TKA patients. Mean microembolic load for TKA patients was 3.83 (range=0–57).

There was no significant change in neuropsychiatric outcome from baseline in these patients at 6 weeks or 6 months. Those patients that experienced cerebral microembolisation did not significantly differ in neuropsychiatric outcome from those that did not.

Conclusion: Intraoperative cerebral microembolisation occurs in almost half of patients during knee arthroplasty. Emboli loads are low and do not appear to cause early or late changes in neuropsychiatric outcome.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 110 - 110
1 Mar 2006
Ackroyd C Newman J Eldridge J
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Introduction: Isolated patello-femoral arthritis occurs in up to 10% of patients suffering osteoarthritis of the knee. Reports of patello-femoral replacements have given indifferent results. We report our experience of 350 cases of the Avon Arthroplasty.

Method: In 1994 after experience with the Lubinus prosthesis which had a 50% failure rate at eight years, we defined the design criteria for a new prosthesis. Since September 1996, 350 knees have been treated with this design. Prospective review was undertaken and 150 knees have reached 2 years and 80 knees are at five years with 10 knees at eight years. The outcome was assessed using pain scores, Bartlett’s patella score and the Oxford knee score.

Results: The patients recovered function rapidly and 20 cases (6%) suffered early complications which resolved. The median pain score improved from 15/40 points to 38 at five years. The movement increased from 114 to 120 at five years. The Bartlett patella score improved from 11/30 points to 25 at five years. The Oxford knee score improved from 19/48 points to 40 points at five years.

The functional results are similar or better than those of a total knee replacement. Fourteen patients developed mal-alignment (4%) two of which required distal realignment. There have been no cases of deep infection, fracture, wear or loosening. Twenty seven knees (7%) developed evidence of disease progression, twenty two of which (6%) have required revision to a total knee replacement. Nineteen patients (5%) complained of some persistent anterior knee pain of uncertain cause.

Conclusions: Results to date show a large improvement in pain and function and this improved design has reduced the problems of mal-alignment and polythene wear. There is a low complication rate and an excellent range of movement. Disease progression remains a problem which is not predictable. This type of prosthesis offers an alternative to total knee replacement in this small group of patients with isolated patello-femoral disease with a low morbidity.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 80 - 81
1 Mar 2006
Pollard T Newman J Barlow N Price J Willett K
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Introduction: Proximal femoral fracture (PFF) is the leading cause of Trauma admission. Deep surgical wound infection occurs in approximately 3% of these patients. The purpose of this study was to assess the cost of deep infection to the patient, in terms of mortality and social consequences, and to the National Health Service, in terms of financial burden.

Methods: 61 consecutive patients (51 females, 10 males) treated for PFF, complicated with deep surgical wound infection over a seven-year period are presented. A control group consisting of 122 patients, without infection, were individually case matched (2:1) for factors that affect outcome after PFF (age, sex, ASA grade, fracture type, operation, and pre-fracture residence, social dependence, and mobility). Outcomes included length of admission (Trauma unit, rehabilitation bed, community hospital), number of operations, antibiotic administration and outpatient treatment, final destination, and mortality at one, three, and six months. A total cost of treatment was obtained from this data and supplied finance department figures.

Results: MRSA was responsible for 31 cases. Infected cases required an average of two wound debridements. 16 patients had a Girdlestones procedure of whom two were subsequently revised to total hip replacement. For all patients, the average Trauma unit admission was 58 days in the infected cases, with a further 40 days spent in rehabilitation or community beds, versus 16 days and 27 days respectively in the controls (p < 0.001). 34% of infected cases died before discharge versus 15% of controls (p = 0.004). For the patients surviving to discharge, the mean total hospital stay was 124 days for the infected cases versus 45 days in the controls (p < 0.001). A higher proportion of the survivors in the control group returned to their original residence compared to the infected survivors (p = 0.002). The mortality rates in the infected group were 15% at 1 month, 31% at 3 months, and 38% at six months, versus 9%, 20%, and 25% respectively in the control group (p = 0.36, 0.12, 0.12). The median cost of treatment per infected case was 23960 versus 7390 per control case.

Conclusions: Deep surgical wound infection after proximal femoral fracture is a devastating complication for both the patient and the NHS. It is associated with a higher in-patient mortality, and fewer survivors return to their pre-fracture residence. Hospital stay is greatly increased and survivors spend 4 months on average in hospital. Additional costs are huge and are incurred at all levels. The extra financial cost of treating a single infected case would fund the treatment of two non-infected cases. These costs should be considered when allocating funds and beds to Trauma services, in addition to ensuring measures known to minimise infection rates are in place.