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Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_III | Pages 242 - 242
1 Nov 2002
Bentley G Goldberg A Biant L Hunter M Carrington R
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Many methods have been described over the past 5 years for repair of articular cartilage defects. The best reported results have been from the use of autologous chondrocyte transplantation (ACT)(1) and mosaicplasty.(2) There have, however, been no prospective clinical trials of these two methods. In this trial 70 patients were prospectively randomized to receive either autologous chondrocyte transplantation (37) or mosaicplasty (33) in the knee. 37 patients were female and 33 male. The average age was 32 years (16 – 44). The indications for surgery were persistent pain and mechanical symptoms in the knee with an isolated defect of the articular cartilage. 38 (56%) were post-traumatic, 12 (16%) due to osteochondritis dissecans, 10 (14%) due to previous meniscectomy, and 10 (14%) due to chondromalacia patellae. The size of the defects ranged from 2cm2 to 12cm2 (mean 4.8cm2). There were 35 defects on the medial femoral condyle, 13 on the lateral femoral condyle, 17 on the patella and 5 on the trochlear. 31 patients were undergoing primary surgery and 39 secondary surgery. All were independently reviewed using the Visual Analogue Pain Score, the Cincinatti Pain Score and the Stanmore Score. Patients were arthroscoped at one year with MRI scan and biopsies where possible.

Results: The visual analogue pain score improved overall from a mean of 5.4 (range 3.4 – 7.4) pre-operatively to 3.9 (1.8 – 5.1) at one year review. Similarly the Cincinatti pain score improved from 6.5 pre-operatively to 10.2 post-operatively and the Cincinatti function score improved from 46 to 62 at one year before sport commenced. Overall 71% (49) patients were excellent or good on the clinical scoring scales, 15% (11) were fair, and 14% (10) were poor. The 10 poor results were no different from the main group with regard to age, sex, pain level or site or size of lesion. However, 5 were secondary procedures, 2 had multiple lesions, and 3 had had previous ruptured anterior cruciate ligaments. Arthroscopy and biopsy of 21 lesions so far after one year has shown mature articular cartilage in 2, and immature cartilage in 19. In all cases there was bonding of the repair tissue to the underlying bone. This study is already clarifying the role of ACT and mosaicplasty in the management of cartilage defects in the knee and also the necessity for the use of periosteal covering membrane.


The purpose of this study was to evaluate the influence of trochlear design in total knee replacement with and without patellar resurfacing.

Methods and Results: In 1992 a trial was set up, including all patients undergoing primary PFC (Johnson & Johnson) total knee replacement. Patients were randomised to either patellar resurfacing or retention. The patients were assessed using the American Knee Society rating, a clinical anterior knee pain score and BOA patient satisfaction score. Assessment was performed without knowing whether the patella had been resurfaced.

In July 1998 we began using the PFC Sigma. This incorporates a deeper trochlear groove with a 5° valgus angle.

We compared the results for the two types of prosthesis. In the PFC group there were 474 knees in 390 patients. Follow-up was from 2 to 9 years (mean 5.5 years). The overall prevalence of anterior knee pain) was 25.1% (58 knees) and 5.3% (13 knees) in the non-resurfaced group (n=231) versus the resurfaced group (n=243) respectively. Anterior knee pain became apparent in all cases within 18 months.

In the PFC sigma group there were 67 knees in 62 patients. Follow-up was from 18 months to 3 years (mean 2 years). The incidence of anterior knee pain was 0 in the resurfaced group (n=30) versus 37.8% (14 knees) in the non-resurfaced group (n=37). Knee scores were lower in the non-resurfaced groups for each prosthesis.

Conclusion: The prevalence of anterior knee pain was significantly higher in knees with non-resurfacing of the patella. The asymmetrical, deeper femoral groove improves anterior knee pain with the resurfaced patella but may contribute to it if not resurfaced. We recommend patellar resurfacing in all cases where technically possible.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 125 - 125
1 Jul 2002
Maruthainar N Graham D Surace F Bentley G
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The issue of preservation or sacrifice of the posterior cruciate ligament in total knee arthroplasty remains unresolved.

We report the results of 200 consecutive total knee arthroplasties performed at our hospital under the direction of the senior author. Pre-operatively, patients were randomly chosen to receive either a Kinemax (posterior cruciate retaining) or a Press-Fit-Condylar (posterior cruciate sacrificing) prosthesis. We implanted 97 Kinemax and 103 Press-Fit-Condylar prostheses which were prospectively followed-up by clinical and radiographic assessment. Review at mean follow-up of 2.7 years showed a satisfactory clinical result in both groups [Surace, et al., 1994].

We present the results of our further review, with maximum follow-up of over nine years (mean: 5.9 years). Revision of the implant has been performed in five knees (three Kinemax and two Press-Fit-Condylar). The polythene spacer had to be replaced in one patient with a Press-Fit-Condylar implant.

Patients were assessed with the Hospital for Special Surgery Knee Score and radiologically assessed with the Knee Society Roentgenographic Evaluation and Scoring System. Pre-operative demographics and disease states of the patients were similar, with an average Hospital for Special Surgery Knee Score of 63. At the latest assessment the average knee score was good (85). Remarkably, the mean knee score for the posterior cruciate sacrifice and the PCL groups remains similar (mean: 85). Radiographic evaluation demonstrated that the prosthetic components of both groups were in comparable alignment. The posterior cruciate ligament retained (Kinemax) patient group showed a mean 5.9 degrees of the valgus angle at the knee. The angle in the posterior cruciate ligament sacrifice (PFC implant) group was 6.2 degrees. Evaluation of the radiolucent depths below the femoral, tibial and any patella component showed a mean total depth of 1.5 mm (pcl retaining) and 1.7 mm (pcl sacrificing).

Our study presents a quantitative perspective of the results of total knee replacement with proven implant systems and performed in a general orthopaedic unit by both consultants and surgeons in training. The Kinemax (Howmedica) and Press-Fit-Condylar (DePuy Johnson and Johnson) implant systems have both previously demonstrated good results and continue to be available with little subsequent modification.

To our knowledge, there have been no other large prospectively randomised studies of posterior cruciate ligament preservation or sacrifice in total knee replacement.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 119 - 119
1 Jul 2002
Davidson A Bentley G
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We clinically and radiologically reviewed 79 uncemented PFC acetabular components inserted by our unit during a seven-year period, June 1991 to June 1998. Of these, 50 (63.3%) were primary and 29 (26.7%) were revision arthroplasties. The mean follow-up was five years (60 months), with a range of 12 to 95 months. Sixteen (20%) were excluded from the study, leaving 63 (26.7%) for review. Three (4.7%) cases were deemed to have failed (at 63, 69, 79 months), all of which were primary arthroplasties. One of them was found to be loose at revision and the other two cups had 2 mm of periacetabular radiolucency in only one zone, but had no definite evidence of loosening.

The remaining 60 (95.3%) cases showed no radiological evidence of migration of any cups, and no hip had a radiolucent line in all three zones of the acetabulum. Clinical review gave a mean Harris hip score of 96.5. Fifty (79.4%) reported no pain from the hip. One case (1.6%) had undergone recent revision of the stem, at which time the cup was found to be stable. Three (4.7%) reported slight, occasional pain. Another three (4.7%) described mild pain that did not compromise their average activities and was relieved by simple analgesia. Two cases (3.2%) complained of moderate pain that placed some limitations on their activities and required regular analgesia, and one elderly patient who had an ankylosed contralateral hip and ipsilateral sciatic nerve palsy described marked pain (1.6%), and these were considered poor outcomes. In all of these cases the cups were clinically and radiologically stable.

In conclusion, 81% of outcomes were excellent, painfree THRs. A further 4.75% had good and 4.75% fair results. 4.75% had poor outcomes and 4.75% of cases failed. We conclude that the PFC cup merits continued use and follow-up, and together with other uncemented cup designs, may produce benefits in the form of quality and longevity of results in total hip arthroplasty.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 157 - 157
1 Jul 2002
Waters T Bentley G
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The purpose of this study was to evaluate the role of patellar resurfacing in total knee replacement surgery. We reviewed 48 patients who had undergone bilateral knee replacement with patellar resurfacing on only one side. Follow-up was from 18 months to 9.5 years and the patients were assessed using the Knee Society rating, a clinical anterior knee pain score and BOA patient satisfaction score. Patients were also asked specifically if they had a preference for either knee. Assessment was performed without knowing which patella had been resurfaced.

52.1% of patients favoured the resurfaced knee, 8% the unresurfaced knee and 39.9% had no particular preference. The overall prevalence of anterior knee pain was 8.3% in the resurfaced cases (3 mild, 1 moderate) and 27.1% in the unresurfaced knees (8 mild, 3 moderate, 2 severe). No significant difference was found between knee scores.

This study shows a significantly higher rate of anterior knee pain in unresurfaced patellae and preference for the resurfaced side.