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Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_14 | Pages 7 - 7
1 Jul 2016
Lokikere N Saraogi A Sonar U Porter M Kay P Wynn-Jones H Shah N
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Distal femoral replacement is an operation long considered as salvage operation for neoplastic conditions. Outcomes of this procedure for difficult knee revisions with bone loss of distal femur have been sparsely reported.

We present the early results of complex revision knee arthroplasty using distal femoral replacement implant, performed for severe osteolysis and bone loss.

Retrospective review of clinic and radiological results of 25 consecutive patients operated at single centre between January 2010 and December 2014. All patients had single type of implant. All data was collected till the latest follow up. Re-revision for any reason was considered as primary end point.

Mean age at surgery was 72.2 years (range 51 – 85 years). Average number of previous knee replacements was 2.28 (range 1 to 6). Most common indications were infection, aseptic loosening and peri-prosthetic fracture. Average follow up was 24.5 months (range: 3–63 months). 1 patient died 8 months post-op due to unrelated reasons. Re-revision rate was 2/25 (8%) during this period. One was re-revised for aseptic loosening and one was revised for peri-prosthetic fracture of femur. Two other peri-prosthetic fractures were managed by open reduction and internal fixation. All 3 peri-prosthetic fractures occurred with low energy trauma.

It is noteworthy that there was no hinge or mechanical failures of the implant. Peri-prosthetic fracture in 12% of patients in this series is of concern. There are no similar studies to compare this data with. The length of the stem, type of fixation of the stem, weight of the distal femoral component of implant can be postulated as factors contributing to risk of peri-prosthetic fracture.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_11 | Pages 18 - 18
1 Jun 2016
Grammatopoulos G Hodhody G Lane J Taylor A Kendrick B Glyn-Jones S
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Image-guided intra-articular hip injection of local-anaesthetic and steroid is commonly used in the management of hip pain. It can be used as a diagnostic and/or therapeutic tool and is of low cost (£75). The aim of this study was to assess how often a hip injection has a therapeutic effect.

This is a retrospective, consecutive, case series of intra-articular hip injections performed in a tertiary referral hospital over a 2-year period (2013–4). Patients were identified from the radiology department's prospectively entered database. Clinical information, reason for injection and subsequent management was obtained from hospital records. All patients prospectively reported their pain levels in a numeric pain scale diary (out of 10) at various time points; pre-, immediately post-, 1st day-, 2nd day- and 2 weeks- post-injection. Only patients with complete pain scores at all time points were included (n=200, of the 250 injections performed over study period, 80%).

The majority of injections were performed for osteoarthritis (OA) treatment (82%). The pain was significantly reduced from a pre-injection score of 7.5 (SD:2) to 5.0 (SD:3) immediately post-injection(p<0.001); only 24 (11%) reported any worsening of pain immediately post-injection. Pain significantly reduced further to 3.8(SD:3) at 2-weeks post-injection (p<0.001). 50% of patients had at least a 3 point drop in reported pain. No improvement was seen in 18 patients and 10 (5%) reported worse pain at 2-weeks compared to pre-injection. Of the OA cohort, 10% have required repeat injections, 45% required no further intervention and 45% underwent or are due for hip replacement. No immediate complications occurred.

Intra-articular hip injection reduced pain in 86% of cases and has delayed any further surgical treatment for at least 2 years in over 50% of OA cases. It is hence a cost-effective treatment modality. Further work is necessary to describe factors predicting response.


Bone & Joint Research
Vol. 5, Issue 6 | Pages 206 - 214
1 Jun 2016
Malak TT Broomfield JAJ Palmer AJR Hopewell S Carr A Brown C Prieto-Alhambra D Glyn-Jones S

Objectives

High failure rates of metal-on-metal hip arthroplasty implants have highlighted the need for more careful introduction and monitoring of new implants and for the evaluation of the safety of medical devices. The National Joint Registry and other regulatory services are unable to detect failing implants at an early enough stage. We aimed to identify validated surrogate markers of long-term outcome in patients undergoing primary total hip arthroplasty (THA).

Methods

We conducted a systematic review of studies evaluating surrogate markers for predicting long-term outcome in primary THA. Long-term outcome was defined as revision rate of an implant at ten years according to National Institute of Health and Care Excellence guidelines. We conducted a search of Medline and Embase (OVID) databases. Separate search strategies were devised for the Cochrane database and Google Scholar. Each search was performed to include articles from the date of their inception to June 8, 2015.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_11 | Pages 13 - 13
1 Jun 2016
Aqil A Patel S Jones G Lewis A Cobb J
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Introduction

Outcomes following large joint arthroplasty are influenced by the accuracy of implant placement. Patient specific (PS) technology has been used in knee arthroplasty surgery however, its application in total hip arthroplasty remains relatively unexplored.

Aims

We investigated whether conventional or PS guides, resulted in a more accurate reconstruction of the pre-operative head centre position.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_13 | Pages 3 - 3
1 Jun 2016
Lokikere N Jakaraddi C Wynn-Jones H Shah N
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Primary total hip replacement (THR) in patients with abnormal/altered proximal femoral anatomy/narrow canals presents a technical challenge. There are only limited standard prosthetic stems available to deal with narrow canals or abnormal morphology. Many prefer to use expensive custom implants which often have a lag time to manufacture and do not always have long term published outcomes.

We present results of the Asian C-stem (which is a standard implant available on the shelf) used in patients predominantly of Caucasian origin with abnormal proximal femoral anatomy.

We retrospectively reviewed clinic-radiological results of 131 patients (131 stems) who underwent primary THR using Asian C-stem at Wrightington Hospital till their latest follow up. Revision for any reason was considered as primary end point.

Mean age at surgery was 50.8 years (16 – 80). The 2 commonest indications were primary osteoarthritis (66 patients) and hip dysplasia (54 patients). Mean follow up was 43.5 months with a minimum follow up of 12 months and maximum follow up of 97 months. There were 2 recurrent dislocations and 1 hip subluxed twice. One dislocation needed revision surgery. 1 patient underwent acetabular revision for loosening. There was no stem failure, obvious loosening or loss of fixation in any patients in our series with regards to the Asian C-stem. There were no infections and intra-operative perforations or fractures.

C-stem Asian is a reliable implant for patients undergoing THR with abnormal proximal femoral anatomy or narrow canals. Long term follow up is essential.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_11 | Pages 29 - 29
1 Jun 2016
Purbach B Siney P Jones HW Kay P Wroblewski B
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Introduction

Primary hip replacement in young active patients is on the increase. Due to the demands set by the patient, implants used in this patient group should have a proven long-term clinical and radiological outcome. We report our results in patients under the age of 50 using the C-Stem femoral component – a cemented triple tapered polished stem.

Methods

Since the C-stem femoral component was introduced into clinical practice in 1993, 6906 C-stems have been used in primary hip replacements at our hospital. In this group, 896 patients were under the age of 50 at the time of surgery. We report the first 300 consecutive C-stems from this group. The surgical technique of using a bone block to allow subsidence and clearing of the calcar to increase loading of the proximal femur medially was routinely used together with a femoral cement gun and pressurizer.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_11 | Pages 32 - 32
1 Jun 2016
Sharma V Shamoon R Maheson M Jones SA
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Introduction

The Corail stem is a fully HA coated tapered implant that has demonstrated long-term success. On the NJR it has become one of the most commonly used implants in the UK. The aim of our study was to document our experience of the revision of this implant together highlighting some important technical considerations.

Patients/Materials & Methods

A retrospective review of a consecutive case series of revision procedures where the Corail stem was extracted. We considered time since implantation, collared or uncollared design, indication for revision, Paprosky classification of femoral deficiency, endo-femoral reconstruction or extended approach/osteotomy, subsequent reconstruction either further primary type implant (cemented or cementless) or revision femoral implant.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_11 | Pages 40 - 40
1 Jun 2016
Johal S Siney P Wroblewski B Purbach B Board T Jones HW
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Introduction

Large acetabular bone defects caused by aseptic loosening are common. Reconstruction of large segmental defects can be challenging. Various implants and operative techniques have been developed to allow further acetabular revision in cases where bone stock is poor. Reconstitution of bone stock is desirable especially in younger patients. The aim of the study was to review the clinical and radiological results of hip revision with structural acetabular bone grafts using fresh frozen allograft and cemented components.

Method

Between 1990 and 2014, 151 first time revisions for aseptic acetabular loosening with acetabular reconstruction with a fresh frozen structural allograft and cemented components were performed at our hospital.

Graft dimensions, number of screws used and socket coverage by the graft were measured on the post-operative AP radiograph.

Follow-up radiographs were analysed for socket loosening, quality of graft union, graft and graft resorption.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_11 | Pages 52 - 52
1 Jun 2016
Grammatopoulos G Kendrick B Glyn-Jones S McLardy-Smith P Taylor A Gundle R
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Introduction

The value of Debridement-Antibiotics-and-Implant-Retention (DAIR) in prosthetic-joint-infection (PJI) is still a matter of debate as most studies to-date are underpowered with variable end-points. In our, tertiary referral, bone infection unit we consider DAIR to be a suitable option in all PJIs with soundly fixed prostheses, despite chronicity. The aims of this study were to define the long-term outcome following DAIR in hip PJI and identify factors that influence it.

Methods

This is a retrospective consecutive case series of DAIRs performed between 1997 and 2013. Only infected cases confirmed by established criteria were included. Data recorded included patient demographics, medical history (ASA grade, Charlson and KLICC scores), type of surgery performed (DAIR or DAIR + exchange of modular components) and organism grown. Outcome measures included complications, implant survivorship and functional outcome (Oxford Hip Score, OHS).


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_8 | Pages 68 - 68
1 May 2016
Jones G Clarke S Jaere M Cobb J
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The treatment of patients with osteoarthritis of the knee and associated extra-articular deformity of the leg is challenging. Current teaching recognises two possible approaches: (1) a total knee replacement (TKR) with intra-articular bone resections to correct the malalignment or (2) an extra-articular osteotomy to correct the malalignment together with a TKR (either simultaneously or staged).

However, a number of these patients only have unicompartmental knee osteoarthritis and, in the absence of an extra-articular deformity would be ideal candidates for joint preserving surgery such as unicompartmental knee replacement (UKR) given its superior functional outcome and lower cost relative to a TKR [1).

We report four cases of medial unicondylar knee replacement, with a simultaneous extra-articular osteotomy to correct deformity, using novel 3D printed patient-specific guides (Embody, UK) (see Figure 1). The procedure was successful in all four patients, and there were no complications. A mean increase in the Oxford knee score of 9.5, and in the EQ5D VAS of 15 was observed.

To our knowledge this is the first report of combined osteotomy and unicompartmental knee replacement for the treatment of extra-articular deformity and knee osteoarthritis. This technically challenging procedure is made possible by a novel 3D printed patient-specific guide which controls osteotomy position, degree of deformity correction (multi-plane if required), and orientates the saw-cuts for the unicompartmental prosthesis according to the corrected leg alignment.

Using 3D printed surgical guides to perform operations not previously possible represents a paradigm shift in knee surgery. We suggest that this joint preserving approach should be considered the preferred treatment option for suitable patients.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_7 | Pages 90 - 90
1 May 2016
Cobb J Collins R Brevadt M Auvinet E Manning V Jones G
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Normal human locomotion entails a rather narrow base of support (BoS), of around 12cm at normal walking speeds. This relatively narrow gait requires good balance, and is beneficial, as it minimises the adduction moment at the knee. Normal knees have a slightly oblique joint line, and slight varus, which allow the normal human to walk rapidly with a narrow BoS. Patients with increased varus and secondary osteoarthritis have a broader BoS, which exacerbates the excessive load, making walking painful and ungainly.

We wondered if there would be a difference between the base of support of patients whose knee kinematics had been preserved, by retaining the native jointline obliquity and the acl, in comparison with those whose alignment had been altered to a mechanically correct ‘neutral’ alignment.

Materials and Methods

Of 201 patients measured following knee arthroplasty, 31 unicondylar patients and 35 total knee patients, with a single primary arthroplasty, and no co-morbidities, over 1 year post-operatively were identified. Two control groups of controls, a younger cohort of 112 people and 17 in an age matched older cohort.

All operations were performed by the same surgeon. The total knees were cruciate retaining devices, inserted in mechanical alignment, and the unicondylar knees were inserted retaining the native alignment and joint-line obliquity.

The gait of all subjects was analysed on an instrumented, calibrated treadmill with underlying force plates. Patients start by walking at a comfortable speed for them for 5 minutes, before the speed of the treadmill is increased at 1/2 km/h increments until maximum walking speed obtained, spending 30 seconds at each. After the flat test, it was then repeated on a downhill slope of 6°.

Base of Support is interpreted as the distance between the centre point of heel strike and toe off from one foot to that of the other.

The top walking speed in the unicondylar group was significantly greater than that of the total knee group, as we reported in 2013.

TKA patients have an average BoS of 14cm, while UKA patients and controls have a 12cm BoS. The BoS did not reduce with speed. This 2cm, or 17% increase in BoS is significant. Shapiro-Wilk tests demonstrate a normal distribution to the results, and ANOVA testing reveals a significant difference (p<0.05) within the groups between the speeds of 4.5 to 9. Post-Hoc Bonferroni testing reveal a significant difference between the TKA group and each of the other three groups.

On the downhill test (figure 1), the mean BoS in the TKA group increased to 16cm. This increase is highly significant, with a p value of <0.001, while the increase in the UKA group at higher speeds failed to reach significance, and the controls both stayed at 12cm. 6 Bi-uni knees tested acted just like the UKAs.

Discussion

A narrow base of support minimises excessive loads across the joint line. Maintenance of jointline obliquity and an ACL enables this feature to be returned to normal following uni, or bi-uni, while a well aligned TKA seems to prevent it.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_9 | Pages 85 - 85
1 May 2016
Asada S Ouyang Y Jones H Ismaily S Noble P
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Introduction

Restoration of knee function after total knee arthroplasty (TKA) often entails a balance between normal kinematics and normal knee stability, especially in performing demanding physical activities. The ultra-congruent (UC) knee design prioritizes stability over kinematics through close conformity between the femoral component and the tibial insert in extension. This configuration is intended to provide AP stability in the absence of the posterior cruciate ligament during activities that would otherwise cause anterior femoral subluxation. In this study we examine the kinematics of an ultra-congruent knee design in comparison with the intact knee and with conventional articulations used in PCL-retaining (CR) and PCL-substituting (PS) TKR designs.

Materials and Methods

The 3D tibio-femoral kinematics of 6 fresh frozen cadaveric human knees were tested during loaded simulation of squatting in a computer-controlled knee testing rig. Muscle forces were simulated by loading rectus femoris and vastus intermedius (150N), vastus lateralis (100N), vastus medialis (75N), and the hamstring muscles (60N) (total: 385N). Testing was performed on the intact knee, and after implanting a standard design of total knee prosthesis with the posterior cruciate ligament intact (CR-TKA), resected (PCL-substituting insert; PS-TKA), and a UC insert (UC-TKA group). The 3D positions of the tibia and femur were tracked with a high resolution 12 camera motion analysis system (Motion Analysis Inc.) and used to position 3D CT reconstructions of each bone. The translation and rotation of the femur with respect to the tibia were calculated by projecting the femoral transcondylar axis onto a plane normal to the longitudinal anatomical axis of the tibia coincident with the transverse axis of the tibial plateau.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_8 | Pages 67 - 67
1 May 2016
Jones G Jaere M Clarke S Cobb J
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Introduction

Opening wedge high tibial osteotomy is an attractive surgical option for physically active patients with early osteoarthritis and varus malalignment. Unfortunately use of this surgical technique is frequently accompanied by an unintended increase in the posterior tibial slope, resulting in anterior tibial translation, and consequent altered knee kinematics and cartilage loading(1).

To address this unintended consequence, it has been recommended that the relative opening of the anteromedial and posterolateral corners of the osteotomy are calculated pre-operatively using trigonometry (1). This calculation assumes that the saw-cut is made parallel to the native posterior slope; yet given the current reliance on 2D images and the ‘surgeon's eye’ to guide the saw-cut, this assumption is questionable.

The aim of this study was to explore how accurately the native posterior tibial slope is reproduced with a traditional freehand osteotomy saw-cut, and whether novel 3D printed patient-specific guides improve this accuracy.

Methods

26 fourth year medical students with no prior experience of performing an osteotomy were asked to perform two osteotomy saw-cuts in foam cortical shell tibiae; one freehand, and one with a 3D printed surgical guide (Embody, London) that was designed using a CT scan of the bone model. The students were instructed to aim for parallelity with a hinge pin which had been inserted (with the use of a highly conforming 3D printed guide) parallel to the posterior slope of the native joint.

For the purpose of analysis, the sawbones were consistently orientated along their mechanical and anatomical tibial axes using custom moulded supports. Digital photographs taken in the plane of the osteotomy were analysed with ImageJ software to calculate the angular difference in the sagittal plane between the hinge-pin and saw-cut. Statistical analysis was performed with SPSS v21 (Chicago, Illinois); a paired t-test was used to compare the freehand and patient-specific guide techniques. Statistical significance was set at a p-value <0.05.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_9 | Pages 92 - 92
1 May 2016
Lancaster-Jones O Al-Hajjar M Williams S Jennings L Thompson J Isaac G Fisher J
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Introduction and Aims

In order to improve the longevity and design of an implant, a wide range of pre-clinical testing conditions should be considered including variations in surgical delivery, and patients' anatomy and biomechanics. The aim of this research study was to determine the effect of the acetabular cup inclination angle with different levels of joint centre mismatch on the magnitude of dynamic microseparation, occurrence and severity of edge loading and the resultant wear rates in a hip joint simulator.

Methods

The six-station Leeds Mark II Anatomical Physiological Hip Joint Simulator and 36mm diameter ceramic-on-ceramic bearings (BIOLOX® delta) were used in this study. A standard gait cycle, with a twin-peak loading (2.5kN peak load and approximately 70N swing phase load), extension/flexion 15°/+30° and internal/external ±10° rotations, was applied. Translational mismatch in the medial-lateral axis between the centres of rotation of the head and the cup were considered. In this study, mismatches of 2, 3 and 4 (mm) were applied. Two acetabular cup inclination angles were investigated; equivalent to 45° and 65° in-vivo. These resulted in a total of six conditions [Figure 1] with n=6 for each condition. Three million cycles were completed under each condition. The lubricant used was 25% (v/v) new-born calf serum supplemented with 0.03% (w/v) sodium azide to retard bacterial growth. The wear of the ceramic bearings were determined using a microbalance (XP205, Mettler Toledo, UK) and a coordinate measuring machine (Legex 322, Mitutoyo, UK). The stripe wear was analysed using RedLux software. The dynamic microseparation displacement was measured using a linear variable differential transformer. Mean wear rates and 95% confidence limits were determined and statistical analysis (one way ANOVA) completed with significance taken at p<0.05. Results Increasing the medial-lateral joint centre mismatch from 2 to 3 to 4mm resulted in an increased dynamic microseparation [Figure 2]. A similar trend was observed for the wear. A higher level of medial-lateral mismatch increased the wear rate under both 45° and 65° cup inclination angle conditions [Figure 3]. The mean wear rates obtained under 65° were significantly higher compared to those obtained under the 45° cup inclination angle conditions for a given medial-lateral mismatch in the joint centre (p=0.02 for 2mm mismatch, p=0.02 for 3 mm mismatch, and p<0.01 for 4mm mismatch).


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_10 | Pages 9 - 9
1 May 2016
Roche C Flurin P Grey S Wright T Zuckerman J Jones R
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Introduction

Due to the predictability of outcomes achieved with reverse shoulder arthroplasty (rTSA), rTSA is increasingly being used in patients where glenoid fixation is compromised due to presence of glenoid wear. There are various methods to achieve glenoid fixation in patients with glenoid wear, including the use of bone grafting behind the glenoid baseplate or the use of augmented glenoid baseplates. This clinical study quantifies clinical outcomes achieved using both techniques in patients with severe glenoid wear at 2 years minimum follow-up.

Methods

80 patients (mean age: 71.6yrs) with 2 years minimum follow-up were treated by 7 fellowship trained orthopaedic surgeons using rTSA with bone graft behind the baseplate or rTSA with an augmented glenoid baseplate in patients with severe posterior glenoid wear. 39 rTSA patients (14 female, avg: 73.1 yrs; 25 male, avg: 71.5 yrs) received an augmented glenoid (cohort composed of 24 patients with an 8° posterior augment baseplate and 15 patients with a 10° superior augment baseplate) for treatment of CTA, RCT, and OA with a medially eroded scapula. 41 rTSA patients (27 female, avg: 73.0 yrs; 14 male, avg: 66.9 yrs) received glenoid bone graft (cohort composed of 5 patients with allograft and 36 patients with autograft) for treatment of CTA, RCT, and OA with a medially eroded scapula. Outcomes were scored using SST, UCLA, ASES, Constant, and SPADI metrics; active abduction, forward flexion, and internal/external rotation were also measured to quantify function. Average follow-up was 31.2 months (augment 28.3; graft 34.1). A two-tailed, unpaired t-test identified differences (p<0.05) in pre-operative, post-operative, and pre-to-post improvements.


Bone & Joint Research
Vol. 5, Issue 5 | Pages 178 - 184
1 May 2016
Dean BJF Jones LD Palmer AJR Macnair RD Brewer PE Jayadev C Wheelton AN Ball DEJ Nandra RS Aujla RS Sykes AE Carr AJ

Objectives

The PROximal Fracture of the Humerus: Evaluation by Randomisation (PROFHER) trial has recently demonstrated that surgery is non-superior to non-operative treatment in the management of displaced proximal humeral fractures. The objective of this study was to assess current surgical practice in the context of the PROFHER trial in terms of patient demographics, injury characteristics and the nature of the surgical treatment.

Methods

A total of ten consecutive patients undergoing surgery for the treatment of a proximal humeral fracture from each of 11 United Kingdom hospitals were retrospectively identified over a 15 month period between January 2014 and March 2015. Data gathered for the 110 patients included patient demographics, injury characteristics, mode of surgical fixation, the grade of operating surgeon and the cost of the surgical implants.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_6 | Pages 23 - 23
1 Feb 2016
Jones M Morris A Pope A Ayer R Breen A
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Purpose and Background:

The spread of upright MRi scanning is a relatively new development in the UK. However, there is a lack of information about whether weight bearing scans confer any additional useful information for low back conditions.

Methods and Results:

Forty-five patient referrals to the upright MRI Department at the AECC for weight bearing lumbar spine scans between November 1st 2014 and June 30th 2015, and the resulting radiologists' reports were reviewed. Age, gender, clinical history, summary of findings, type of weight bearing scanning performed (sitting, standing, flexion, extension) were abstracted. All patients were scanned in a 0.5T Paramed MRopen scanner and all also received supine lumbar spine sagittal and axial scans.

The patients comprised 18 females and 27 males, mean age 52 years, (SD 15.5). Thirty had leg pain, 6 of which was bilateral. In 15, a stenotic lesion was suspected. Other reasons for referral were; possible malignancy (1), effects of degenerative change (4), spondylolisthesis (2), fracture, (1), previous surgery (3), trauma (1), sacroiliitis (1) and instability (3).

In 12/45 cases, reportable findings were more prominent, and sometimes only identifiable, on weight bearing scans, while in a further 4, the reverse was true. All but one of these involved disruption of the spinal or root canals. Eight of them also involved positional alignment.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_5 | Pages 49 - 49
1 Feb 2016
d'Entremont AG Jones CE Wilson DR Mulpuri K
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Perthes disease is a childhood disorder often resulting in femoral head deformity. Categorical/dichotomous outcomes of deformity are typical clinically, however quantitative, continuous measures, such as Sphericity Deviation Score (SDS), are critical for studying interventions. SDS uses radiographs in two planes to quantify femoral head deformity. Limitations of SDS may include non-orthogonal planes and lost details due to projections. We applied this method in 3D, with specific objectives to: 1. Develop SDS-like sphericity measures from 3D data 2. Obtain 2D and 3D sphericity for normal and Perthes hips 3. Compare slice-based (3D) and projection-based (2D) sphericity CT images of 16 normal (8 subjects) and 5 Perthes hips (4 subjects) were segmented to create 3D hip models. Ethics board approval was obtained for this study. SDS consists of roundness error (RE) in two planes and ellipsoid deformation (ED) between planes. We implemented a modified SDS which was applied to (a) orthogonal projections simulating radiographs (sagittal/coronal; 2D-mSDS), and (b) largest radii slices (sagittal/coronal; 3D-mSDS). Mean 2D-mSDS was higher for Perthes (27.2 (SD 11.4)) than normal (11.9 (SD 4.1)). Mean 3D-mSDS showed similar trends, but was higher than 2D (Perthes 33.6 (SD 5.3), normals 17.0 (SD 3.1)). Unlike 2D-mSDS, 3D-mSDS showed no overlap between groups. For Perthes hips, 2D-mSDS was consistent with SDS. For normal hips, 2D-mSDS was higher than expected (similar to Stulberg II). Projection-based (2D) measures may produce lower mSDS due to spatial averaging. Slice-based (3D) measures may better distinguish between normal and Perthes shapes, which may better differentiate effectiveness of treatments.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 89 - 89
1 Jan 2016
Cobb J Collins R Manning V Zannotto M Moore E Jones G
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The Oxford Hip Score (OHS), the Harris Hip Score (HHS) and WOMAC are examples of patient reported outcome measures (PROMs) have well documented ceiling effects, with many patients clustered close to full marks following arthroplasty. Any arthroplasty that offers superior function would therefore fail to be detectable using these metrics. Two recent well conducted randomised clinical trials made exactly this error, by using OHS and WOMAC to detect a differences in outcome between hip resurfacing and hip arthroplasty despite published data already showing in single arm studies that these two procedures score close to full marks using both PROMS.

We had observed that patients with hip resurfacing arthroplasty (HRA) were able to walk faster and with more normal stride length than patients with well performing hip replacements, but that these objective differences in gait were not captured by PROMs. In an attempt to capture these differences, we developed a patient centred outcome measure (PCOM) using a method developed by Philip Noble's group. This allows patients to select the functions that matter to them personally against which the success of their own operation will be measured.

Our null hypothesis was that this PCOM would be no more successful than the OHS in discriminating between types of hip arthroplasty.

22 patients with a well performing Hip Resurfacing Arthroplasty were identified. These were closely matched by age, sex, BMI, height, preop diagnosis with 22 patients with a well performing conventional THA. Both were compared with healthy controls using the novel PCOM and in a gait lab.

Results

PROMs for the two groups were similar, while HRA scored higher in the PCOM. The 9% difference was significant (p<0.05).

At top walking speed, HRA were 10% faster, with a 9% longer stride length.

Discussion

Outcome measures should be able to detect differences that are clinically relevant to patients and their surgeons. The currently used hip scores are not capable of delivering this distinction, and assume that most hip replacements are effectively perfect. While the function of hip replacements is indeed very good, with satisfaction rates high, objective measures of function are essential for innovators who are trying to deliver improved functional outcome.

The 9% difference in PCOM found in this small study reflects the higher activity levels reported by many, and of similar magnitude to the 10% difference in top walking speed, despite no detectable difference in conventional PROMS. PCOMs may offer further insight into differences in function. For investigators who wish to develop improvements to hip arthroplasty, PCOMs and objective measures of gait may describe differences that matter more to patients than conventional hip scores.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_4 | Pages 24 - 24
1 Jan 2016
St Mart J Whittingham-Jones P Davies N Waters T
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Introduction

Bone loss in the distal femur and proximal tibia is frequently encountered with both complex primary and revision knee replacement surgery. Metaphyseal sleeves provide a good option for enhanced fixation in managing such defects on both the tibia and femur. We present our results in 48 patients (50 knees) with a minimum 12 month follow up (range 12 to 45).

Methods

48 patients (50 knees) who had revision knee arthroplasty for either septic or aseptic loosening. All were graded Type II or III using the Anderson Orthopaedic Research Institute (AORI) grading system of both femoral and tibial defects. A large portion of aseptic loosening revisions were for extreme osteolysis of a bicondylar knee prosthesis.