Abstract
Purpose
Comparison between Aprotinin and Tranexamic acid on blood conservation in scoliosis surgery.
Null hypothesis
There is no difference in the control of blood loss between 2 drugs.
Methods and results
Medical records of 40 (20 received Aprotinin and 20 Received Tranexamic acid) patients that underwent posterior correction of scoliosis were evaluated for age, weight, aetiology, Cobb angle, levels instrumented, cell saver use, pre and post-operative HB levels. The results are as under.
Conclusion
Both drugs appears to be equally effective in controlling the blood loss. The study is limited by small numbers and retrospective design, but available data does not prove superiority of one over the other drug.
