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Research

ANATOMY AND MICROENVIRONMENT OF THE INTERVERTEBRAL DISC

The European Orthopaedic Research Society (EORS) 31st Annual Meeting, Porto, Portugal, 27–29 September 2023. Part 1 of 2.



Abstract

Degeneration of the intervertebral disc (IVD), and subsequent low back pain, is an almost inevitable cause of disability. The underlying mechanisms are complex and current therapeutic strategies mainly focus on symptomatic relief rather than on the intrinsic regeneration of the IVD. This talk will provide an overview of special anatomical features and the composition of the IVD as well as its cellular microenvironment. Selected promising conceptional regenerative approaches will be discussed.


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