PAPER 148: TOTAL JOINT REPLACEMENT CLINICAL OUTCOMES: THE DIFFERENCE BETWEEN GENDERS

Abstract

Purpose: Medical research has classically been based on the male model, this is no different in the design of arthroplasty implants. Focus has recently shifted to gender-specific implant design but little evidence exists in the literature as to gender specific outcomes. We hypothesized that outcomes in arthroplasty patients are affected by gender.

Method: Patients were retrospectively identified from a prospectively collected database of total joint arthroplasties performed at one center. Six surgeons performed 1123 primary unilateral cemented TKA’s, and 989 primary unilateral cementless THA’s over a period of seven years. General demographic data was collected along with preoperative and 1-year clinical outcomes including the Knee Society (KSS)/Harris Hip Scores (HHS) and Oxford Knee/Hip scores. These were compared to determine differences, if any, between genders using independent samples t-test and chi-square test for proportions.

Results: The TKA sample was comprised of 540 (55%) females and 449 (45%) males. The THA sample included 744 (66%) females and 379 (34%) males. In the TKA group, females were significantly younger, had higher BMI and differing rates of comorbidities and complications. Female KSS, Oxford and flexion outcomes were significantly inferior to male scores pre-operatively and at 1-year follow-up. Significantly more females reported higher pain scores than males from pre-op to one year. Interestingly, females showed significantly more improvement from pre-op to one year in both scores. In the THR group there were varying rates of complications and comorbidities by gender. Females did significantly worse in the HHS and Oxford hip score from pre-op until one year when results equalized. Similarly pain scores were higher for females preop and at 6 weeks but became equivalent thereafter. Females showed significantly greater improvement from pre-op to 1 year for both outcome scores.

Conclusion: As reported in the literature, results of this study indicate that women choose arthroplasty at a later stage of disease than men do, presenting with inferior functional status. The effect of waiting seems most marked in the knee arthroplasty population with inferior outcomes and pain relief persisting out to one year. Surgeons must counsel females differently about expectations and recovery in joint arthroplasty.