DOES THE USE OF CELL SALVAGE AND TRANEXAMIC ACID REDUCE THE NEED FOR HOMOLOGOUS BLOOD TRANSFUSION IN REVISION HIP SURGERY?

Phillips S, Chavan R, Porter M, et al. DOES THE USE OF CELL SALVAGE AND TRANEXAMIC ACID REDUCE THE NEED FOR HOMOLOGOUS BLOOD TRANSFUSION IN REVISION HIP SURGERY?. Orthop Procs. 2008;90-B(SUPP_II):297-297. doi:10.1302/0301-620X.90BSUPP_II.0900297d

Phillips, SJ, et al. “DOES THE USE OF CELL SALVAGE AND TRANEXAMIC ACID REDUCE THE NEED FOR HOMOLOGOUS BLOOD TRANSFUSION IN REVISION HIP SURGERY?.” Orthopaedic Proceedings, vol. 90-B, no. SUPP_II, 2008, pp. 297-297., https://doi.org/10.1302/0301-620X.90BSUPP_II.0900297d

Phillips, S., Chavan, R., Porter, M., Kay, P., Hodgkinson, Purbach, B., Hoad Reddick, A., & Frayne, J. (2008). DOES THE USE OF CELL SALVAGE AND TRANEXAMIC ACID REDUCE THE NEED FOR HOMOLOGOUS BLOOD TRANSFUSION IN REVISION HIP SURGERY?. Orthopaedic Proceedings, 90-B(SUPP_II), 297-297. https://doi.org/10.1302/0301-620X.90BSUPP_II.0900297d

Phillips, S., Chavan, R., Porter, M., Kay, P., Hodgkinson, Purbach, B. et al. (2008) “DOES THE USE OF CELL SALVAGE AND TRANEXAMIC ACID REDUCE THE NEED FOR HOMOLOGOUS BLOOD TRANSFUSION IN REVISION HIP SURGERY?.” Orthopaedic Proceedings, 90-B(SUPP_II), pp. 297-297. Available at: https://doi.org/10.1302/0301-620X.90BSUPP_II.0900297d

Phillips, SJ, R Chavan, ML Porter, P Kay, Hodgkinson, B Purbach, A Hoad Reddick, and JM Frayne. “DOES THE USE OF CELL SALVAGE AND TRANEXAMIC ACID REDUCE THE NEED FOR HOMOLOGOUS BLOOD TRANSFUSION IN REVISION HIP SURGERY?.” Orthopaedic Proceedings 90-B, no. SUPP_II (2008): 297-297. https://doi.org/10.1302/0301-620X.90BSUPP_II.0900297d

Phillips S, Chavan R, Porter M, Kay P, Hodgkinson, Purbach B, et al. DOES THE USE OF CELL SALVAGE AND TRANEXAMIC ACID REDUCE THE NEED FOR HOMOLOGOUS BLOOD TRANSFUSION IN REVISION HIP SURGERY?. Orthop Procs. 2008 Jul 1;90-B(SUPP_II):297-297. https://doi.org/10.1302/0301-620X.90BSUPP_II.0900297d

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Abstract

Introduction: We performed a retrospective case control study in 80 patients who under went revision hip surgery at our unit.

Methodology: Group A (40 patients), received tranexamic acid and intra-operative cell salvage. Group B (40 patients) a matched control did not receive these treatments. Each group was divided into 4 sub groups; revision of both components, revision of components + bone grafting, revision acetabular component +/− bone grafting and revision femoral component +/− bone graft.

Results: In group A the total number of units transfused was 139 compared to 52 in group B. This represents a reduction in blood usage of 37%. The mean amount of blood transfused from cell salvage in each group was 858mls, 477mls, 228mls and 464mls. There was a significant difference in the amount of blood returned between the groups (p< 0.0001). In the control group 37 patients needed transfusion, in the study group 22 (p< 0.0001). At our unit a cost analysis calculation has shown total revenue saving of £88,000 and a potential saving throughout the trust of £316,688 per year.

Discussion: To our knowledge this is the first study to examine the use of cell salvage and tranexamic acid in revision hip surgery. Our results show that a significant reduction in blood transfusion can be made using this technique. It is vital that blood conserving strategies are developed so that future revision surgery can continue.

Correspondence should be addressed to The Secretary, BHS, c/o BOA, The Royal College of Surgeons, 35–43 Lincoln’s Inn Fields, London WC2A 3PE.