Tricalcium-phosphate and hydroxyapatite bone-graft extender for use in impaction grafting revision surgery: AN IN VITRO STUDY ON HUMAN FEMORA

E. H. van Haaren; T. H. Smit; K. Phipps; P. I. J. M. Wuisman; G. Blunn; I. C. Heyligers

doi:10.1302/0301-620X.87B2.14749

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Tricalcium-phosphate and hydroxyapatite bone-graft extender for use in impaction grafting revision surgery

AN IN VITRO STUDY ON HUMAN FEMORA

E. H. van Haaren
T. H. Smit
K. Phipps
P. I. J. M. Wuisman
G. Blunn
I. C. Heyligers

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Tricalcium-phosphate and hydroxyapatite bone-graft extender for use in impaction grafting revision surgery

van Haaren EH, Smit TH, Phipps K, Wuisman PIJM, Blunn G, Heyligers IC. Tricalcium-phosphate and hydroxyapatite bone-graft extender for use in impaction grafting revision surgery. J Bone Joint Surg Br. 2005;87-B(2):267-271. doi:10.1302/0301-620X.87B2.14749

van Haaren, E. H., et al. “Tricalcium-phosphate and hydroxyapatite bone-graft extender for use in impaction grafting revision surgery.” The Journal of Bone & Joint Surgery British Volume, vol. 87-B, no. 2, 2005, pp. 267-271., https://doi.org/10.1302/0301-620X.87B2.14749

van Haaren, E. H., Smit, T. H., Phipps, K., Wuisman, P. I. J. M., Blunn, G., & Heyligers, I. C. (2005). Tricalcium-phosphate and hydroxyapatite bone-graft extender for use in impaction grafting revision surgery. The Journal of Bone & Joint Surgery British Volume, 87-B(2), 267-271. https://doi.org/10.1302/0301-620X.87B2.14749

van Haaren, E. H., Smit, T. H., Phipps, K., Wuisman, P. I. J. M., Blunn, G. and Heyligers, I. C. (2005) “Tricalcium-phosphate and hydroxyapatite bone-graft extender for use in impaction grafting revision surgery.” The Journal of Bone & Joint Surgery British Volume, 87-B(2), pp. 267-271. Available at: https://doi.org/10.1302/0301-620X.87B2.14749

van Haaren, E. H., T. H. Smit, K. Phipps, P. I. J. M. Wuisman, G. Blunn, and I. C. Heyligers. “Tricalcium-phosphate and hydroxyapatite bone-graft extender for use in impaction grafting revision surgery.” The Journal of Bone & Joint Surgery British Volume 87-B, no. 2 (2005): 267-271. https://doi.org/10.1302/0301-620X.87B2.14749

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Abstract

Impacted morsellised allografts have been used successfully to address the problem of poor bone stock in revision surgery. However, there are concerns about the transmission of pathogens, the high cost and the shortage of supply of donor bone. Bone-graft extenders, such as tricalcium phosphate (TCP) and hydroxyapatite (HA), have been developed to minimise the use of donor bone. In a human cadaver model we have evaluated the surgical and mechanical feasibility of a TCP/HA bone-graft extender during impaction grafting revision surgery.

A TCP/HA allograft mix increased the risk of producing a fissure in the femur during the impaction procedure, but provided a higher initial mechanical stability when compared with bone graft alone. The implications of the use of this type of graft extender in impaction grafting revision surgery are discussed.

Correspondence should be sent to Dr I. C. Heyligers at Department of Orthopaedic Surgery, Atrium Medical Centre, P O Box 4446, 6401 CX Heerlen, The Netherlands; e-mail: heyligers@atriummc.nl

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Journal

The Journal of Bone & Joint Surgery British Volume

Volume

87-B No.2 | Pages 267 - 271

Section

Research

Published

01 February 2005

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E. H. van Haaren

Research Fellow

Department of Orthopaedic Surgery, Skeletal Tissue Engineering Group Amsterdam (STEGA)

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T. H. Smit

Biomechanical Engineer

Department of Physics and Medical Technology STEGA Vrije Universiteit Medical Centre, P O Box 7057, 1007 MB Amsterdam, The Netherlands.

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K. Phipps

Biomechanical Engineer

The Centre for Biomedical Engineering, Institute of Orthopaedics and Musculo-Skeletal Science, University College London, RNOH Trust, Brockley Hill, Stanmore, Middlesex HA7 4LP, UK.

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P. I. J. M. Wuisman

Orthopaedic Surgeon

Department of Orthopaedic Surgery, Skeletal Tissue Engineering Group Amsterdam (STEGA)

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G. Blunn

Biomechanical Engineer

The Centre for Biomedical Engineering, Institute of Orthopaedics and Musculo-Skeletal Science, University College London, RNOH Trust, Brockley Hill, Stanmore, Middlesex HA7 4LP, UK.

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I. C. Heyligers

Orthopaedic Surgeon

Department of Orthopaedic Surgery, Skeletal Tissue Engineering Group Amsterdam (STEGA)

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