Abstract
1. The case is reported of a woman aged sixty-five with widespread osteosclerosis as a feature of IgA myelomatosis.
2. Improvement was noted after treatment by cyclophosphamide and prednisolone.
3. Only two previously reported cases of myeloma with osteosclerosis of comparable extent have been found, but in forty-seven other cases in the literature some sclerosis has been noted.
4. The finding of sclerotic lesions should not rule out multiple myeloma.