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DOMINANT INHERITANCE IN FAMILIAL GENERALISED ARTICULAR HYPERMOBILITY



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Abstract

Two individuals with generalised articular hypermobility are described. There are many affected members in both kindreds, and the pedigrees indicate that the disorder is transmitted as an autosomal dominant trait. Orthopaedic complications and deformities are common in one family but absent in the other. It is suggested therefore that the two disorders are distinct and separate genetic entities.

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