Abstract
1. In growing rats oestrogen, cortisone and thyroxine in high doses suppress bone formation, and this effect is probably part of a general suppression of body growth.
2. Growth hormone and thyroxine in small doses stimulate both body growth and bone formation.
3. Testosterone has no effect on bone formation.
4. Oestrogen and cortisone suppress bone resorption. The effect of cortisone may be modified in conditions of calcium depletion.
5. Thyroxine appears on the other hand to increase bone resorption.
6. Testosterone has no effect on bone resorption.
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