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AGE CHANGES IN THE ORGANIC FRACTION OF BONE



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Abstract

1. The relative concentrations of organic material in adjacent microscopic regions of bone have been studied by three methods, and the results suggest that this concentration varies considerably.

2. The variations in the organic concentration in bone have been correlated with the age of the bone and its inorganic concentration.

3. It is suggested that the progressive calcification of bone as its age increases, occurs, to some extent, at the expense of the organic fraction of the tissue.

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