Abstract
1. The arrangement of collagen fibres in the secondary osteones in human femora and tibiae has been examined. The fibres were observed in paraffin sections stained by Weidenreich's method.
2. Three fibre patterns have been observed. They differ from one another in the relative numbers of longitudinal and circumferential fibres which they contain, and in the degree of lamellation which they exhibit.
3. The incidence of the three fibre patterns has been correlated with the relative ages of the regions of bone in which they occur.
4. The possibility of a correlation between variations in fibre pattern and certain recent microradiographic observations is discussed.