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THE BEHAVIOUR OF PENICILLIN IN SYNOVIAL CAVITIES



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Abstract

1. The behaviour of penicillin injected locally into knee joints is investigated and found to be the only satisfactory way of using the drug in joint wounds and infections.

2. Penicillin persists within the joint for forty-eight hours after injection unless the effusion is being actively absorbed.

3. The additional administration of penicillin by intramuscular injection is recommended when other considerations demand it.

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